检索结果-南通市图书馆

维普期刊数据库

Technologies and studies of gas exchange in two-stroke aircraft piston engine:A review

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Aeronautics 2024年第1期37卷 24-50页

作者： yu ZHOU Xueyu LI Shuiting DING Shuai ZHAO Kun ZHU Longtao SHAO farong DU Gerui WANG Zheng XU Research Institute of Aero-Engine Beihang UniversityBeijing 100191China Aircraft/Engine Integrated System Safety Beijing Key Laboratory Beijing 100191China School of Transportation Science and Engineering Beihang UniversityBeijing 100191China Civil Aviation University of China Tianjin 300300China Aero Engine Academy of China Beijing 101304China School of Energy and Power Engineering Beihang UniversityBeijing 100191China Beihang Hangzhou Innovation Institute yuhang Hangzhou 310052China

The in-cylinder gas exchange process is crucial to the power performance of two-stroke aircraft piston engines,which is easily influenced by complex factors such as high-altitude performance variation and in-cylinder flow *** paper reviews the development history and characteristics of gas exchange types,as well as the current state of theory and the validation methods of gas exchange technology,while also discusses the trends of cutting-edge technologies in the *** paper provides a theoretical foundation for the optimization and engineering design of gas exchange systems and,more importantly,points out that the innovation of gas exchange types,the modification of theoretical models,and the technology of variable airflow organization are the key future research directions in this field.

关键词： Aircraft piston engine Aircraft power systems Gas exchange High-altitude performance In-cylinder flow Two-stroke Unmanned Aerial Vehicles(UAVs)

维普期刊数据库

Effect of Octadecadienoic Acid on Proliferation and Apoptosis of Glioma Cells and Its Mechanism

在线全文

学校读者我要写书评

暂无评论

Medicinal Plant 2023年第4期14卷 24-26,34页

作者： Mingren XIE Xia yuAN Shan QI Lei yu farong yu School of Public Security Gansu University of Political Science and LawLanzhou 730070China

[Objectives] To explore the inhibitory effect of octadecadienoic acid (ODA) on proliferation and apoptosis of glioma cells and its mechanism. [Methods] Cultured human glioma cells (cell density 2×10^(6) cells/L) were divided into three groups: solvent control group (DMSO, 30 μL/L), 5-FU group (10 mg/L) and octadecadienoic acid group (0.3, 0.6, 1.2 mg/L). The toxic effects of ODA on glioma cells were detected by trypan blue and thiazolium blue (MTT). The expression of P53, PI3K, P21, PKB/Akt and caspase-9 protein in glioma cells were detected by enzyme-linked immunosorbent assay (ELISA). [Results] The cell count under optical microscope showed that the inhibition rate of cell proliferation in low, medium and high dose ODA groups and 5-FU group was significantly higher than that in solvent control group ( P 0.05). The results of MTT showed that compared with the solvent control group, the inhibition rate of cell proliferation in low, medium and high dose ODA groups and 5-FU group significantly increased ( P <0.01);compared with 5-FU group, the inhibition rate of cell proliferation in high dose ODA group significantly increased ( P <0.01). The results of flow cytometry showed that compared with the solvent control group, the number of cells in G_(0)/G_(1) phase increased significantly ( P <0.05, P <0.01), the number of cells in G_(2)/M phase decreased significantly ( P <0.01) and the apoptosis rate increased significantly ( P <0.01) in the low, medium and high dose ODA groups and 5-FU group;compared with 5-FU group, the number of cells in G_(2)/M phase decreased significantly ( P <0.01) and the apoptosis rate increased significantly ( P <0.01) in ODA group. ELISA testing results showed that the expression levels of P53, P13K and PKB/Akt in low, medium and high dose ODA groups and 5-FU group were significantly lower than those in solvent control group ( P <0.01), and only the expression level

关键词： Octadecadienoic acid Glioma cells Inhibition effect Apoptosis

Effects of Noise Pollution on Functions of the Liver and Kidney of Rats

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Meteorological and Environmental Research 2018年第4期9卷 41-43页

作者： yu farong yu Xin Li Zuoping Lian Xiuzhen Xie Mingren Li Denglou Key Laboratory of Evidence of Science and Technology Research and Application of Gansu Province Gansu Institute of Political Science and Law Lanzhou 730070 China University of Southern California Los Angeles 90033 USA

To study the effects of noise pollution on the functions of the liver and kidney of rats, a total of 40 male SPF Wistar rats were randomly divided into a control group and three experimental groups. The rats in the experimental groups were respectively stimulated with 38, 55 and 70 dB noise for 15 days, and the levels of blood components were determined by an automatic biochemical analyzer. The results showed that in compari-son with the control group, the level of the blood glucose in the experimental groups increased by 23.53%, 52.94% and 88.24%, respectively, and the differences were statistically significant （P〈0.01）. The levels of triglyceride in the blood rose by 20.83%, 38.54% and 79.68%, respectively, and the differences were also statistically significant （P〈0.01）. The level of globulin in the blood increased by 16.49%, 21.13% and 51.78%, and the level of albumin in the blood rose by 9.51 %, 12.67% and 17.89%, respectively. The level of total bilirubin in the blood increased by 27.04%, 41.63% and 73.67%, respectively, and the differences were statistically significant （P〈0.01）. The level of creatinine in the blood rose by 9.72%, 10.21% and 20.99%, respectively. The level of amylase in the blood reduced by 6.6%, 13.05% and 23.89%, respectively. The level of creatine kinase in the blood decreased by 19.81%, 27.37% and 36.81 %, respectively, and the level of urea in the blood reduced by 11.19%, 12.77% and 19.26%, respectively. The results revealed that noise pollution could significantly affect the levels of blood components and the functions of the liver and kidney of rats.

关键词： Noise pollution Functions of the liver and kidney Wistar rats

Semisynthesis of homogeneous spike RBD glycoforms from SARS-CoV-2 for profiling the correlations between glycan composition and function

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

National Science Review 2024年第2期11卷 145-154页

作者： farong Ye Cheng Li Feng-Liang Liu Xinliang Liu Peng Xu Rong-Hua Luo Wenping Song Yong-Tang Zheng Tianlei Ying Biao yu Ping Wang Center for Chemical Glycobiology Frontiers Science Center for Transformative Molecules Zhangjiang Institute for Advanced Study School of Chemistry and Chemical Engineering Shanghai Jiao Tong University MOE/NHC/CAMS Key Laboratory of Medical Molecular Virology Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection Shanghai Institute of Infectious Disease and BiosecurityShanghai Engineering Research Center for Synthetic ImmunologySchool of Basic Medical Sciences Shanghai Medical College Fudan University Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of yunnan Province Center for Biosafety Mega-Science Kunming Institute of ZoologyChinese Academy of Sciences State Key Laboratory of Bioorganic and Natural Products Chemistry Center for Excellence in Molecular Synthesis Shanghai Institute of Organic Chemistry Chinese Academy of Sciences Shenzhen Research Institute of Shanghai Jiao Tong University

Vaccines have been the primary remedy in the global fight against coronavirus disease 2019（COVID-19）.The receptor-binding domain（RBD） of the spike protein, a critical viral immunogen, is affected by the heterogeneity of its glycan structures and relatively low immunogenicity. Here, we describe a scalable synthetic platform that enables the precise synthesis of homogeneously glycosylated RBD, facilitating the elucidation of carbohydrate structure–function relationships. Five homogeneously glycosylated RBDs bearing biantennary glycans were prepared, three of which were conjugated to T-helper epitope(Tpep) from tetanus toxoid to improve their weak immune response. Relative to natural HEK293-derived RBD, synthetic RBDs with biantennary N-glycan elicited a higher level of neutralising antibodies against SARS-CoV-2 in mice. Furthermore, RBDs containing Tpepelicited significant immune responses in transgenic mice expressing human angiotensin-converting enzyme 2. Our collective data suggest that trimming the N-glycans and Tpepconjugation of RBD could potentially serve as an effective strategy for developing subunit vaccines providing efficient protection.

关键词： peptide ligation glycosylation glycoprotein

圈养条件下亚成体雌性金钱豹肺微血管铸型的扫描电镜观察

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

兽类学报 2014年第2期34卷 205-208页

作者：谢明仁俞文张璐俞发荣甘肃省证据科学技术研究与应用重点实验室兰州730070

金钱豹（Pantherapardus）属国家一级重点保护野生动物。关于人（Homosapiens，真炳攸等，1990）、鼠（Ferrieira et al．，2001）、家兔（俞诗源和李重阳，1995）、牦牛（Bosgrunniens，柳东阳，2007）、绵羊（Schraufnagel et al．，1... 详细信息

金钱豹（Pantherapardus）属国家一级重点保护野生动物。关于人（Homosapiens，真炳攸等，1990）、鼠（Ferrieira et al．，2001）、家兔（俞诗源和李重阳，1995）、牦牛（Bosgrunniens，柳东阳，2007）、绵羊（Schraufnagel et al．，1995）、

关键词：金钱豹肺微血管构筑

维普期刊数据库

Gas exchange optimization in aircraft engines using sustainable aviation fuel:A design of experiment and genetic algorithm approach

在线全文

学校读者我要写书评

暂无评论

Energy and AI

Energy and AI 2024年第3期17卷 261-280页

作者： Zheng Xu Jinze Pei Shuiting Ding Longfei Chen Shuai Zhao Xiaowei Shen Kun Zhu Longtao Shao Zhiming Zhong Huansong Yan farong Du Xueyu Li Pengfei Yang Shenghui Zhong yu Zhou Hangzhou International Innovation Institute Beihang UniversityHangzhou311115China Research Institute of Aero-Engine Beihang UniversityBeijing102206China Civil Aviation University of China Tianjin300300China Aircraft/Engine Integrated System Safety Beijing Key Laboratory Beijing100083China Aero Engine Academy of China Beijing101304China School of Energy and Power Engineering Beihang UniversityBeijing100083China AVIC Chengdu Aircraft Design and Research Institute Chengdu610091China AVIC Nanjing Engineering Institute of Aircraft Systems Nanjing211106China School of Transportation Science and Engineering Beihang UniversityBeijing100083China Faculty of Science and Engineering University of Nottingham Ningbo ChinaNingbo315100China

The poppet valves two-stroke(PV2S)aircraft engine fueled with sustainable aviation fuel is a promising option for general aviation and unmanned aerial vehicle propulsion due to its high power-to-weight ratio,uniform torque output,and flexible valve ***,its high-altitude gas exchange performance remains unexplored,presenting new opportunities for optimization through artificial intelligence(AI)*** study uses validated 1D+3D models to evaluate the high-altitude gas exchange performance of PV2S aircraft *** valve timings of the PV2S engine exhibit considerable flexibility,thus the Latin hypercube design of experiments(DoE)methodology is employed to fit a response surface model.A genetic algorithm(GA)is applied to iteratively optimize valve timings for varying *** optimization process reveals that increasing the intake duration while decreasing the exhaust duration and valve overlap angles can significantly enhance high-altitude gas exchange *** optimal valve overlap angle emerged as 93°CA at sea level and 82°CA at 4000 m *** effects of operating parameters,including engine speed,load,and exhaust back pressure,on the gas exchange process at varying altitudes are further *** higher engine speed increases trapping efficiency but decreases the delivery ratio and charging efficiency at various *** effect is especially pronounced at elevated *** increase in exhaust back pressure will significantly reduce the delivery ratio and increase the trapping *** study demonstrates that integrating DoE with AI algorithms can enhance the high-altitude performance of aircraft engines,serving as a valuable reference for further optimization efforts.

关键词： Poppet valves two-stroke Design of experiment Genetic algorithm optimization Heavy fuel aircraft engine High altitude gas exchange performance

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

虚拟解剖技术研究进展的文献计量分析

中国公共安全(学术版) 2018年第2期 108-113页

作者：杨博俞发荣甘肃政法学院甘肃省证据科学技术研究与应用重点实验室

为更客观和直观地展示虚拟解剖技术的研究成果,探索虚拟解剖技术的研究热点和演进趋势,为司法鉴定领域研究人员提供参考依据。通过文献计量的方法对CNKI数据库中关于虚拟解剖技术的文献,分别从文献发表年度、来源期刊、文献作者、作者... 详细信息

为更客观和直观地展示虚拟解剖技术的研究成果,探索虚拟解剖技术的研究热点和演进趋势,为司法鉴定领域研究人员提供参考依据。通过文献计量的方法对CNKI数据库中关于虚拟解剖技术的文献,分别从文献发表年度、来源期刊、文献作者、作者机构、关键词、引文、研究对象和方法等方面进行深入挖掘并通过数据表和图谱的形式呈现出来。研究发现虚拟解剖技术是当前研究的热点;作者、作者机构、来源期刊相对集中,研究阵地突出;虚拟解剖技术面临研究领域广泛但不深入的问题。虚拟解剖技术在司法实践中虽仍有较多不足之处但发展前景广阔。因此在未来发展中应结合新技术的应用逐渐弥补虚拟解剖技术的短板,使其真正服务于临床和司法实践。

关键词：虚拟解剖文献计量分析研究进展法医

Effects of Maca Extract on Endurance and Blood Antioxidant Enzyme Activity of Rats

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Medicinal Plant 2018年第4期9卷 94-96页

作者： Zuoping LI farong yu Mingren XIE Sports Teaching Department Gansu Institute of Political Science and Law Key Laboratory of Evidence of Science and Technology Research and Application Gansu Institute of Political Science and Law

[Objectives] The aim was to investigate the effects of maca extract on endurance and blood antioxidative enzyme activity of rats.[Methods]The Wistar rats treated with/without maca extract( 8. 0,16. 0,and 32. 0 g/kg) were given with free access to circulating *** administration was conducted for 15 consecutive d. On the 16 th d,the endurance and blood malondialdehyde( MDA),superoxide dismutase( SOD) and glutathione peroxidase( GSH-Px) levels of the rats were determined. [Results] Compared with those of the rats without maca extract treatment,the swimming time before sinking of the rats administered with 8. 0,16. 0,and 32. 0 g/kg of maca extract was increased by 34. 38%,84. 25% and 126. 07%( P < 0. 01),the total swimming time was increased by 37. 42%,47. 03% and 107. 24%( P <0. 01),the times of sinking was reduced by 17. 65%,33. 28% and 55. 50%( P < 0. 05,P < 0. 01),the blood MDA level was reduced by 34.63%,54. 13% and 63. 73%( P < 0. 01),the blood SOD activity was increased by 67. 78%,108. 25% and 154. 49%( P < 0. 01),and the blood GSH-Px level was increased by 48. 57%,110. 28% and 154. 86%( P < 0. 01). [Conclusions]Maca extract has the functions of resisting fatigue and enhancing athletic,and the mechanisms are related to the reduction of blood MDA level and the increase of blood SOD and GSH-Px activity.

关键词： Maca extract Endurance Antioxidative enzymes Wistar rat

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

全息技术在物证技术领域的应用

中国公共安全(学术版) 2017年第1期 133-137页

作者：杨博俞发荣甘肃政法学院

近年来,物证技术工作面临诸多难题。传统的物证记录、提取、检验鉴定方法缺陷凸显,不能满足当前司法实践的需要。全息技术因其真正的三维显现为物证技术的发展提供了一种新思路、新方法。从当前物证技术工作所存在的问题入手,通过检索... 详细信息

近年来,物证技术工作面临诸多难题。传统的物证记录、提取、检验鉴定方法缺陷凸显,不能满足当前司法实践的需要。全息技术因其真正的三维显现为物证技术的发展提供了一种新思路、新方法。从当前物证技术工作所存在的问题入手,通过检索近年国内外全息技术在物证技术领域中应用的相关文献进行综合分析,对全息技术的技术原理以及在物证技术领域中的应用等多个方面进行综述,指出了当前制约全息技术应用于物证技术领域的瓶颈,以期以新技术的引用推动物证技术的进步。

关键词：全息技术物证技术检验提取