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Non-alcoholic fatty liver disease is not independent risk factor for cardiovascular disease event:A cohort study

World Journal of Hepatology 2020年第6期12卷 323-331页

作者： Nima Motamed Hossein Ajdarkosh Maral Ahmadi Dhayaneethie Perumal G Hossein Ashrafi Mehdi Nikkhah Amir Hossein Faraji Mansooreh Maadi Mahmoodreza Khoonsari Nader Rezaie Behzad Farahani Fahimeh Safarnezhad Tameshkel Mitra Ameli Mahshid Panahi mohammad Hadi Karbalaie Niya farhad Zamani Department of Social Medicine Zanjan University of Medical SciencesZanjan ***Iran Gastrointestinal and Liver Diseases Research Center Iran University of Medical SciencesTehran ***Iran Faculty of Science Engineering and ComputingKingston UniversityKingstonLondon KT12EEUnited Kingdom Cancer Theme SEC Faculty Penrhyn Road Kingston UniversityLondon KT12EEUnited Kingdom Department of Pulmonology Firouzgar HospitalIran University of Medical SciencesTehran ***Iran Department of Cardiology Iran University of Medical SciencesTehran ***Iran

BACKGROUND There are no consistent results between previous studies for an independent association between non-alcoholic fatty liver disease(NAFLD)and cardiovascular disease(CVD)*** To determine if there is an independent association between NAFLD and CVD *** In the present study,valid outcome data of 4808 subjects were available for phase 2 of our cohort *** subjects had been followed up for seven years from phase 1,beginning in 2009-2010 to phase 2 during *** and multiple Cox proportional models were used to determine the association between NAFLD in the primary phase of the cohort and subsequent fatal and non-fatal CVD events during *** The incidence of non-fatal CVD events in males with NAFLD was significantly higher(P=0.004)than in males without NAFLD.A positive association was demonstrated between NAFLD and non-fatal CVD events in males(Hazard ratio=1.606;95%CI:1.166-2.212;P=0.004)by the simple Cox proportional hazard model,but no independent association was detected between these in the multiple Cox *** No independent association was detected between NAFLD and *** is likely that diabetes mellitus and age may be the principle mediators in this regard.

关键词： Non-alcoholic fatty liver disease Cardiovascular disease Cohort Type 2 diabetes mellitus Risk factor Follow up

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Evaluation of Serum Iron, Zinc and Their Relationships with Glycemic Control Status in Iranian Elderly Women with Type 1 Diabetes Mellitus

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Journal of Pharmacy and Pharmacology 2015年第9期3卷 411-416页

作者： Mahshid mohammadian Attabak Toofani Milani mohammad Reza Hassas Siamak Rashidi Elmira Roshani Asl Sadegh Rostaminasab Mohadeseh Nemati Farid Javandust Narmin Mokarizadeh farhad fathi younesi Department of Biochemistry Urmia University of Medical Sciences Urmia 57147 West Azerbaij'an Iran Aria Medical Laboratory Urmia University of Medical Sciences Sanandaj *** Kurdistan Iran Department of Medicine Urmia University of Medical Sciences Urmia 5 714 7 West Azerbaijan Iran Department of Biochemistry Faculty of Medicine Shahid Beheshti University of Medical Sciences Tehran *** Tehran Iran

It seems that defects on micro-minerals levels have an etiologic role involved in type 1 diabetes mellitus pathogenicity. The aim of our study were to evaluate the serum levels of zinc and iron and investigate their possible relationship between these biochemical parameters with demographic conditions and glycemic control in patients with type 1 diabetes mellitus disorder. In this case-control based study, 68 female with type 1 diabetes mellitus with a mean age of 52.2 ±2 as case group and 122 healthy women as a control group with a mean age of 49/4 ±3/2 were investigated .for biochemical analysis ,10 mL fasting venous blood sample were obtained from each subjects. FBS （fasting blood glucose）, fructosamine （glycemic control parameter） were determined （spectrophotometry method, （pars azmoon, Iran）, nitroblue tetrazoline method respectively）.serum zinc level with colorimetric method （Biorex-UK） and serum iron with photometric method （pars azmoon, Iran） were determined. Statistical analysis using SPSS software performed. Significant levels considered as P 〈 0.05. According to this study there is statistically significant difference between serum levels of iron and zinc in patients with type 1 diabetes compared to controls .indeed serum level of iron and zinc had lower level in patient group toward controls. In patients group, there are a positive correlation between age and decreased level of serum zinc （P 〈 0.05）. Also there was a significant negative correlation between the glycemic control status and serum zinc. Other studied parameters concluded BMI （body mass index）, Weight and height have not significant difference between groups. The decrease in serum iron and zinc level in women with type 1 diabetes may be related to low dietary intake or increased excretion of micro minerals or the presence of confounding factors that require more extensive intervention studies to confirm it.

关键词： Typel diabetes mellitus Iron Zinc glycemic control Iran.

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Incidence of Enterobius vermicularis in acute appendicitis: A systematic review and meta-analysis

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Journal of Acute Disease 2020年第4期9卷 152-156页

作者： Seyed Ahmad Hashemi Saeed Hosseyni Teshnizi farhad Vafaei Ali Ganji mohammadMontazami Sadeghi Azadeh Mizani Azar Shokri Vector-borne Diseases Research Center North Khorasan University of Medical SciencesBojnurdIran Infectious and Tropical Diseases Research Center Hormozgan Health InstituteHormozgan University of Medical SciencesBandar AbbasIran School of Medicine North Khorasan University of Medical SciencesBojnurdIran Department of Parasitology and Mycology School of MedicineMazandaran University of Medical SciencesSariIran

Objective: To evaluate the incidence of Enterobius vermicularis (E. vermicularis) in appendectomies in Iran from 1993 to 2018 . Methods: Data were systematically collected on the electronic databases including PubMed, GoogleScholar, ScienceDirect, Scopus, Web of Science, Magiran, Irandoc (Bareket), IranMedex, and Scientific Information Database in English or Persian. Six articles including 29694 cases of appendicitis with 258 positive cases of infection withE. vermicularis were eligible to enter into this systematic review and meta-analysis. Results: The overall prevalence of E. vermicularis in appendicitis in Iran was 1% (95%CI=0.00-0.02) with the highest rate of 3% (95%CI=0.02-0.03) and lowest rate of 0% (95%CI=0.00-0.01). Conclusions: Prevalence of E. vermicularis infectionin appendicitis in Iran is low and has no statistically significant correlation with age and gender.

关键词： Enterobius vermicularis Appendicitis Iran Systematic review Meta-analysis

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A Low Power and High Bandwidth Anti Aliasing Filter with Transconductance Structure for DAB Receivers

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通讯和计算机（中英文版） 2011年第5期8卷 373-380页

作者： mohammad Mehdi farhad Sattar Mirzakuchaki Engineering-Department of Electronic Islamic Azad University Saveh branch Saveh 39197-15179 lran Electrical Engineering Department Electronic Research Center Iran University of Science ＆ Technology Tehran 16846 Iran

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Understanding divergent domestication traits from the whole-genome sequencing of swamp-and river-buffalo populations

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National Science Review 2020年第3期7卷 686-701页

作者： Xier Luo Yu Zhou Bing Zhang Yi Zhang Xiaobo Wang Tong Feng Zhipeng Li Kuiqing Cui Zhiqiang Wang Chan Luo Hui Li Yanfei Deng Fenghua Lu Jianlin Han Yongwang Miao Huaming Mao Xiaoyan Yi Cheng Ai Shigang Wu Alun Li Zhichao Wu Zijun Zhuo Do Da Giang Bikash Mitra mohammad farhad Vahidi Shahid Mansoor Sahar Ahmed Al-Bayatti Eka Meutia Sari Neena Amatya Gorkhali Sigit Prastowo Laiba Shafique Guoyou Ye Qian Qian Baoshan Chen Deshun Shi Jue Ruan Qingyou Liu State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources Guangxi University CAS Key Laboratory of Genome Sciences and Information Beijing Institute of Genomics Chinese Academy of Sciences National Engineering Laboratory for Animal Breeding Key Laboratory of Animal Genetics Breeding and Reproduction of Ministry of Agriculture and Rural AffairsCollege of Animal Science and Technology China Agricultural University Guangdong Laboratory for Lingnan Modern Agriculture Genome Analysis Laboratory of the Ministry of Agriculture Agricultural Genomics Institute at Shenzhen Chinese Academy of Agricultural Sciences CAAS-ILRI Joint Laboratory on Livestock and Forage Genetic Resources Institute of Animal ScienceChinese Academy of Agricultural Sciences International Livestock Research Institute Faculty of Animal Science and Technology Yunnan Agricultural University Bacgiang Agriculture and Forestry University Cellular Immunology Lab Department of Zoology University of North Bengal Animal Biotechnology Department Agricultural Biotechnology Research Institute of Iran-North Region 11. National Institute for Biotechnology and Genetic Engineering 12. Animal Genetic Sources DepartmentDirectorate of Animal Resources Ministry of Agriculture 13. Department of Animal Science Faculty of Agriculture Syiah Kuala University 14. Animal Breeding DivisionNational Animal Science Research Institute Nepal Agriculture Research Council 15. Animal Science Department Universitas Sebelas Maret 16. International Rice Research Institute

Domesticated buffaloes have been integral to rice-paddy agro-ecosystems for millennia, yet relatively little is known about the buffalo genomics. Here, we sequenced and assembled reference genomes for both swamp and river buffaloes and we re-sequenced 230 individuals(132 swamp buffaloes and 98 river buffaloes)sampled from across Asia and Europe. Beyond the many actionable insights that our study revealed about the domestication, basic physiology and breeding of buffalo, we made the striking discovery that the divergent domestication traits between swamp and river buffaloes can be explained with recent selections of genes on social behavior, digestion metabolism, strengths and milk production.

关键词： Bubalus bubalis genome buffalo domestication re-sequencing traits

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Numerical Study on the Serviceability Performance of Unstiffened and Stiffened Steel Plates

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Journal of Civil Engineering and Architecture 2019年第9期13卷 553-561页

作者： farhad Riahi Tadeh Zirakian Bijan Sanaati Samrand mohammad Karimi Dept.of Civil Engineering Islamic Azad UniversityMahabad BranchMahabad 591393-3137Iran Dept.of Civil Engineering and Construction Management California State UniversityNorthridgeCA 91330USA Dept.of Civil Engineering Islamic Azad UniversityBoukan BranchBoukan 7356716-33986Iran

In this paper,the effects of transverse stiffeners for improving the buckling and post-buckling behaviors of thin steel plates under compressive loading have been investigated through consideration of two parameters,*** number and ***,the deformations associated with the buckling stability of unstiffened and stiffened plates have been evaluated through detailed *** numerical models have been developed using ABAQUS and the buckling behavior has been studied through performing nonlinear static ***’s largest deformation has been considered for comparison purposes which may not be necessarily located in the center of the plate *** use of stiffeners by and large increases the load-bearing capacity of the plates;however,it is shown that lack of proper detailing of stiffened plates may unfavorably result in the reduction of the load-bearing capacity and,in general,adversely affect the stability performance of such commonly-used slender members.

关键词： Plate stiffener buckling post-buckling numerical simulation

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Invasive candidiasis in critical care setting, updated recommendations from “Invasive Fungal Infections-Clinical Forum”, Iran

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World Journal of Critical Care Medicine 2014年第4期3卷 102-112页

作者： Ashraf Elhoufi Arezoo Ahmadi Amir mohammad Hashem Asnaashari mohammad Ali Davarpanah Behrooz Farzanegan Bidgoli Omid Moradi Moghaddam mohammad Torabi-Nami Saeed Abbasi Malak El-Sobky Ali Ghaziani mohammad Hossein Jarrahzadeh Reza Shahrami Farzad Shirazian farhad Soltani Homeira Yazdinejad Farid Zand Department of Critical Care Medicine Dubai Hospital Dubai Health Authority Department of Anesthesiology and Critical Care Sina Hospital Tehran University of Medical Sciences Department of Pulmonology and Critical Care Ghaem Hospital Mashhad University of Medical Sciences Department of Infectious Diseases and Tropical Medicine Shiraz University of Medical Sciences Tracheal Disease Research Center Shahid Behesti University of Medical Sciences Department of Anesthesiology and Critical Care Rasoul-e-Akram Hospital Iran University of Medical Sciences Department of Neuroscience School of Advanced Medical Sciences and Technologies Shiraz University of Medical Sciences Behphar Scientific Committee Behphar Group Anesthesiology and Critical Care Research Center Isfahan University of Medical Sciences Invasive Fungal Infections-Clinical Forum Intensive Care and Burn Units Motahhari Hospital Intensive Care Unit Vali-e-Asr Hospital NAJA University Department of Anesthesiology and Critical Care Golestan Hospital Ahwaz Jundishapur University of Medical Sciences Department of Anesthesiology and Critical Care Taleghani Hospital Shahid Beheshti University of Medical Sciences Shiraz Anesthesiology and Critical Care Research Center Shiraz University of Medical Sciences

Invasive candidiasis(IC) bears a high risk of morbidity and mortality in the intensive care units(ICU). With the current advances in critical care and the use of widespectrum antibiotics, invasive fungal infections(IFIs) and IC in particular, have turned into a growing concern in the ICU. Further to blood cultures, some auxil-iary laboratory tests and biomarkers are developed to enable an earlier detection of infection, however these test are neither consistently available nor validated in our setting. On the other hand, patients' clinical status and local epidemiology data may justify the empiric antifungal approach using the proper antifungal option. The clinical approach to the management of IC in febrile, non-neutropenic critically ill patients has been defined in available international guidelines; nevertheless such recommendations need to be customized when applied to our local practice. Over the past three years, Iranian experts from intensive care and infectious diseases disciplines have tried to draw a consensus on the management of IFI with a particular focus on IC in the ICU. The established IFI-clinical forum(IFI-CF), comprising the scientific leaders in the field, has recently come up with and updated recommendation on the same(June 2014). The purpose of this review is to put together literature insights and Iranian experts' opinion at the IFI-CF, to propose an updated practical overview on recommended approaches for the management of IC in the ICU.

关键词： Invasive candidiasis Intensive care unit IFI-clinical forum Recommendations Iran

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