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Determination of Chlorine in Human Urine by Detecting Backscattering Signals with a New Optical Assembly

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Chinese Chemical Letters 2006年第5期17卷 679-682页

作者： Ke Jun TAN Yuan fang li cheng Zhi HUANG Xue lian liU College of Chemistry and Chemical Engineering Southwest University Chongqing 400715

Detection of backscattering signals （BSS） generally suffers from the interference of reflected light, and it is hard to apply these signals for analytical purpose. Herein we provided an optical assembly, which effectively eliminated the interference of reflected light so that the scattering signals of analyte could be measured distinctly. With this assembly, chlorine in human urine could be detected with the limit of detection （LOD） of 2.0 ng/mL by measuring the enhanced BSS signals produced between the interactions of chlorine with silver nitrate.

关键词： Chlorine urine backscattering signals.

c-Jun N-terminal kinase 3 deficiency protects axotomized retinal ganglion cells via affecting mitochondria involved apoptosis pathway

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International Journal of Ophthalmology(English edition) 2019年第1期12卷 30-37页

作者： Rong-Rong Wang cheng-fang li De-Zu Wang cheng-Wu Zhang Gui-Xiang liu Qingdao University Department of Ophthalmology Jimo Traditional Chinese Medicine Hospital Department of Ophthalmology Affiliated Qingdao Hiser Hospital of Qingdao University Institute of Advanced Materials Nanjing Tech University Department of Ophthalmology Affiliated Hospital of the Medical College of Qingdao University

AIM: To illustrate the isoform-specific role and mechanism of c-Jun N-terminal kinases(JNKs) in mouse optic nerve axotomy induced neurotrauma. METHODS: We firstly investigated the expression of JNK1, JNK2, and JNK3 in the retinal ganglion cells(RGCs) by double-immunofluorescent staining. Then we created optic nerve axotomy model in wild type as well as JNK1, JNK2, JNK3, isoform specific gene deficiency mice. With that, we checked the protein expression profile of JNKs and its active form, and quantified the survival RGCs number by immunofluorescence staining. We further explored the molecules underlying isoform specific protective effect by real-time polymerase chain reaction(PCR) and Western blotting assay. RESULTS: We found that all the three isoforms of JNKs were expressed in the RGCs. Deficiency of JNK3, but not JNK1 or JNK2, significantly alleviated optic nerve axotomyinduced RGCs apoptosis. We further established that expression of Noxa, a pro-apoptotic member of BH3 family, was significantly suppressed only in JNK3 gene deficiency mice. But tumor necrosis factor receptor 1(TNFR1) and Fas, two key modulators of death receptor mediated apoptosis pathway, did not display obvious change in the expression. CONCLUSION: It is suggested that mitochondria mediated apoptosis, but not death receptor mediated apoptosis got involved in the JNK3 gene deficiency induced RGCs protection. Our study provides a novel insight into the isoform-specific role of JNKs in neurotrauma and indicates some cues for its therapeutics.

关键词： retinal ganglion cells c-Jun N-terminal kinases optic nerve mitochondria Noxa neurotrauma

Study of glue extrusion after endoscopic N-butyl-2-cyanoacrylate injection on gastric variceal bleeding

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World Journal of Gastroenterology 2009年第39期15卷 4945-4951页

作者： Yan-Mei Wang liu-fang cheng Nan li Kai Wu Jun-Shan Zhai Ya-Wen Wang Department of Gastroenterology the Second Affiliated Hospital of PLA General Hospital Beijing 100091 China

AIM:To investigate glue extrusion after endoscopic N-butyl-2-cyanoacrylate injection on gastric variceal bleeding and to evaluate the long-term efficacy and safety of this ***:A total of 148 cirrhotic patients in our hospital with esophagogastric variceal bleeding(EGVB) were included in this study.N-butyl-2-cyanoacrylate was mixed with lipiodol in a 1:1 ratio and injected as a bolus of 1-3 mL according to variceal *** underwent endoscopic follow-up the next week,fourth week,second month,fourth month,and seventh month after injection and then every 6 mo to determine the cast *** abdominal X-ray fi lm and ultrasound or computed tomographic scan were also carried out in order to evaluate the time of variceal disappearance and complete extrusion of the *** average follow-up time was 13.1 ***:The instantaneous hemostatic rate was 96.2%.Early re-bleeding after injection in 9 cases(6.2%) was estimated from rejection of *** re-bleeding occurred in 12 patients(8.1%) at 2-18 *** glue cast was extruded into the lumen within one month in 86.1% of patients and eliminated within one *** erosion was seen at the injection position and mucosa edema in the second *** glue casts were extruded in 18 patients(12.1%) after one week and in 64 patients(42.8%) after two *** kinds of glue clumping shapes and colors on endoscopic examination were observed in 127 patients(86.1%) within one month,including punctiform,globular,pillar and *** one patients(27.9%) had glue extrusion after 3 mo and 28 patients(28.9%) after six *** extrusion time was not related to the injection volume of *** was seen in 70.2%(104 cases) *** main complication was re-bleeding resulting from *** prognosis of the patients depended on the severity of the underlying liver ***:Endoscopic injection of cyanoacrylate is highly effective for gastric varices *** glue clump

关键词： Gastric variceal bleeding Glue extruded N-butyl-2-cyanoacrylate Portal hypertension

Human cytomegalovirus DNA and immediate early protein 1/2 are highly associated with glioma and prognosis

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Protein & Cell 2020年第7期11卷 525-533页

作者： Le Wen Fei Zhao Yong Qiu Shuang cheng Jin-Yan Sun Wei fang Simon Rayner Michael A.McVoy Xing-Jun Jiang Qiyi Tang fang-cheng li Fei Hu Min-Hua Luo Joint Center of Translational Precision Medicine Guangzhou Institute of PediatricsGuangzhou Women and Children's Medical CenterGuangzhou 510623China State Key Laboratory of Virology CAS Center for Excellence in Brain Science and Itelligence TechnologyWuhan Instute of VirologyWuhan 430071China Chinese Institute for Brain Research Beijing 102206China Wuhan Brain Hospital Ministry of TransportationWuhan 430010China Depatment of Medical Genetics Oslo University Hospital and University of OsloOsloNorway Department of Pediatrics Virginia Commonwealth University School of MedicineRichmondVirginiaUSA Department of Neurosurgery Xiangya HospitalCentral South UniversityChangha 410008China Department of Microbiology Howard University College of MedicineWashingtonDCUSA University of Chinese Academy of Sciences Bejing 100049China

Dear Editor,Gliomas are the most common brain tumors in adults which encompass all primary central nervous system(CNS)tumors of glial cell *** World Health Organization(WHO)classifies gliomas into four grades based on the histologic/prognostic *** of the unclear etiol-ogy and pathogenesis,therapeutic efficacy and prognosis is poor.

关键词： glioma prognosis pathogenesis

Endometriosis of the lung: A case report and review of literature

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World Journal of Clinical Cases 2023年第18期11卷 4326-4333页

作者： Jin Yao Hong Zheng Hui Nie cheng-fang li Wen Zhang Jin-Jing Wang Department of Pathology Affiliated Hospital of Zunyi Medical UniversityZunyi 563000Guizhou ProvinceChina

BACKGROUND Lung endometriosis is an extremely rare gynecological *** literature reports suggest that the majority of patients will present with only generic symptoms,such as hemoptysis,pneumothorax,and hemopneumothorax,which often leads to *** date,there are 18 case reports of lung endometriosis that describe the clinical manifestation,imaging changes,treatment,and prognosis of the *** provide further insights into this rare disease,we present a new case report and a brief review of pulmonary *** SUMMARY We report here about a 19-year-old woman who was admitted to the hospital for repeated catamenial hemoptysis over a 3-mo *** tomography(CT)imaging during menstruation revealed patchy high-density shadows,approximately 0.5 cm3 in size,in the right middle lobe of the *** patient’s hemoptysis and changes in the CT scans resolved after *** right middle lobectomy,right lower lung repair,and closed thoracic drainage were *** histopathology confirmed lung *** was no recurrence of symptoms at the 6 mo *** We propose diagnosing lung endometriosis by thoroughly taking reproductive history,clinical details,imaging,and histopathology followed by treatment with surgical resection.

关键词： Lung endometriosis Immunophenotype Differential diagnosis Pathogenesis Case report

Regeneration of Al-doped liNi_(0.5)Co_(0.2)Mn_(0.3)O_(2) cathode material by simulated hydrometallurgy leachate of spent lithium-ion batteries

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Transactions of Nonferrous Metals Society of China 2022年第2期32卷 593-603页

作者： fang-cheng li Gang ZHANG Zong-liang ZHANG Jian YANG fang-yang liU Ming JIA liang-xing JIANG School of Metallurgy and Environment Central South UniversityChangsha 410083China Zhongtian Supercapacitor Technology Co. Ltd.Nantong 226463China Zhongtian Emerging Materials Co. Ltd.Nantong 226463China

A uniform Al-doped liNi_(0.5)Co_(0.2)Mn_(0.3)O_(2) cathode material was prepared using a coprecipitation method to take advantage of the positive effect of Al on regenerated NCM(Ni,Co,Mn)cathode materials and ameliorate cumbersome and high-cost impurity removal processes during lithium-ion battery *** the Al^(3+) content in the leachate was 1 at.%with respect to the total amount of transition metals(Ni,Co,and Mn),the produced Al-doped NCM cathode material increased concentrations of lattice oxygen and Ni^(2+).The initial specific capacity at 0.1C was 167.4 mA·h/g,with a capacity retention of 79.1%after 400 cycles at ***,this Al-doped sample showed improved rate performance and a smaller electrochemical *** findings provide a reference for developing industrial processes to resynthesize cathode materials with improved electrochemical performance by incorporating Al^(3+) impurities produced during lithium-ion battery recycling.

关键词： spent lithium-ion battery regeneration Al doping ternary cathode material coprecipitation

A Hybrid Approach for Pavement Crack Detection Using Mask R-CNN and Vision Transformer Model

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Computers, Materials & Continua 2025年第1期82卷 561-577页

作者： Shorouq Alshawabkeh li Wu Daojun Dong Yao cheng liping li Faculty of Engineering China University of GeosciencesWuhan430074China

Detecting pavement cracks is critical for road safety and infrastructure *** methods,relying on manual inspection and basic image processing,are time-consuming and prone to *** deep-learning(DL)methods automate crack detection,but many still struggle with variable crack patterns and environmental *** study aims to address these limitations by introducing the Masker Transformer,a novel hybrid deep learning model that integrates the precise localization capabilities of Mask Region-based Convolutional Neural Network(Mask R-CNN)with the global contextual awareness of Vision Transformer(ViT).The research focuses on leveraging the strengths of both architectures to enhance segmentation accuracy and adaptability across different pavement *** evaluated the performance of theMaskerTransformer against other state-of-theartmodels such asU-Net,TransformerU-Net(TransUNet),U-NetTransformer(UNETr),SwinU-NetTransformer(Swin-UNETr),You Only Look Once version 8(YoloV8),and Mask R-CNN using two benchmark datasets:Crack500 and *** findings reveal that the MaskerTransformer significantly outperforms the existing models,achieving the highest Dice SimilarityCoefficient(DSC),precision,recall,and F1-Score across both ***,the model attained a DSC of 80.04%on Crack500 and 91.37%on DeepCrack,demonstrating superior segmentation accuracy and *** high precision and recall rates further substantiate its effectiveness in real-world applications,suggesting that the Masker Transformer can serve as a robust tool for automated pavement crack detection,potentially replacing more traditional methods.

关键词： Pavement crack segmentation transportation deep learning vision transformer Mask R-CNN image segmentation

Tailoring light–Matter Interactions in Overcoupled Resonator for Biomolecule Recognition and Detection

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Nano-Micro Letters 2025年第1期17卷 262-280页

作者： Dongxiao li Hong Zhou Zhihao Ren cheng Xu chengkuo Lee Department of Electrical and Computer Engineering National University of SingaporeSingapore 117583Singapore Center for Intelligent Sensors and MEMS(CISM) National University of SingaporeSingapore 117608Singapore

Plasmonic nanoantennas provide unique opportunities for precise control of light–matter coupling in surface-enhanced infrared absorption(SEIRA)spectroscopy,but most of the resonant systems realized so far suffer from the obstacles of low sensitivity,narrow bandwidth,and asymmetric Fano resonance ***,we demonstrated an overcoupled resonator with a high plasmon-molecule coupling coefficient(μ)(OC-Hμresonator)by precisely controlling the radiation loss channel,the resonator-oscillator coupling channel,and the frequency detuning *** observed a strong dependence of the sensing performance on the coupling state,and demonstrated that OC-Hμresonator has excellent sensing properties of ultra-sensitive(7.25%nm^(−1)),ultra-broadband(3–10μm),and immune asymmetric Fano *** characteristics represent a breakthrough in SEIRA technology and lay the foundation for specific recognition of biomolecules,trace detection,and protein secondary structure analysis using a single array(array size is 100×100μm^(2)).In addition,with the assistance of machine learning,mixture classification,concentration prediction and spectral reconstruction were achieved with the highest accuracy of 100%.Finally,we demonstrated the potential of OC-Hμresonator for SARS-CoV-2 *** findings will promote the wider application of SEIRA technology,while providing new ideas for other enhanced spectroscopy technologies,quantum photonics and studying light–matter interactions.

关键词： Plasmonic nanoantennas light-matter interaction Surface-enhanced infrared absorption Overcoupled Biosensing

A Multi-Objective Particle Swarm Optimization Algorithm Based on Decomposition and Multi-Selection Strategy

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Computers, Materials & Continua 2025年第1期82卷 997-1026页

作者： li Ma Cai Dai Xingsi Xue cheng Peng School of Computer Science Shaanxi Normal UniversityXi’an710119China Fujian Provincial Key Laboratory of Big Data Mining and Applications Fujian University of TechnologyFuzhou350118China Information Construction and Management Center and Institute of Artificial Intelligence and Educational New Productivity Ningxia Normal UniversityGuyuan756099China

The multi-objective particle swarm optimization algorithm(MOPSO)is widely used to solve multi-objective optimization *** the article,amulti-objective particle swarm optimization algorithmbased on decomposition and multi-selection strategy is proposed to improve the search ***,two update strategies based on decomposition are used to update the evolving population and external archive,***,a multiselection strategy is *** first strategy is for the subspace without a non-dominated *** the neighbor particles,the particle with the smallest penalty-based boundary intersection value is selected as the global optimal solution and the particle far away fromthe search particle and the global optimal solution is selected as the personal optimal solution to enhance global *** second strategy is for the subspace with a non-dominated *** the neighbor particles,two particles are randomly selected,one as the global optimal solution and the other as the personal optimal solution,to enhance local *** third strategy is for Pareto optimal front(PF)discontinuity,which is identified by the cumulative number of iterations of the subspace without non-dominated *** the subsequent iteration,a new probability distribution is used to select from the remaining subspaces to ***,an adaptive inertia weight update strategy based on the dominated degree is designed to further improve the search ***,the proposed algorithmis compared with fivemulti-objective particle swarm optimization algorithms and five multi-objective evolutionary algorithms on 22 test *** results show that the proposed algorithm has better performance.

关键词： Multi-objective optimization multi-objective particle swarm optimization decomposition multi-selection strategy