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Engineering high-performance dielectric chiral shells with enhanced chiral fields for sensitive chiral biosensor

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Rare Metals 2024年第3期43卷 1197-1206页

作者： Yi-fan wang Shan-Shan Huang Zhen-Dong Dai Shi-Lin Xian Xuan-Nan Wu Fu-Hua Gao Yi-Dong Hou College of Physics Sichuan UniversityChengdu610065China Graduate School of Sichuan University Sichuan UniversityChengdu610065China

Chiral metamaterials have been a topic of significant research interest in recent years due to their potential for various applications in nanophotonic devices and chiral ***,the intrinsic Ohmic loss in surface plasmonic resonance has limited their practical use,resulting in large light dissipation and weak chiroptical ***,we report on the development of high-performance dielectric chiral shells(DCS)through a two-step Si deposition process on a self-assembled microsphere *** form DCS sample completely oyercomes the cancelation effect originated from the disorder property of the micro-sphere monolayer in macroscale,and at a wavelength of approximately 710 nm,the measured optimal chiral signal(g-factor)and transmittance can reach up to 0.7 and 0.3,*** strong chiroptical effect comes from the asymmetric circular displacement currents(i.e.,magnetic modes)enabled by the specific shell *** chiral shell geometry,electromagnetic properties,sensor sensitivity of chiral molecules and figure of merit are systematically *** DCSs demonstrate highly sensitive detection of chiral biomolecules owing to their easily accessible geometry and enhanced uniform chiral field.

关键词： Dielectric chiral shells(DCS) Si deposition Magnetic resonance Highly sensitive sensor Chiral field

Sharp Isolated Toughness Bound for Fractional(k,m)-Deleted Graphs

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Acta Mathematicae Applicatae Sinica 2024年

作者： Wei GAO Wei-fan wang Yao-jun CHEN Department of Mathematics Nanjing University School of Information Science and Technology Yunnan Normal University Department of Mathematics Zhejiang Normal University

Modifiable risk factors for esophageal cancer in endoscopic screening population:A modeling study

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Chinese Medical Journal 2024年第3期137卷 350-352页

作者： Qian Zhang fan wang Hao Feng Jie Xing Shengtao Zhu Hao Zhang Yang Li Wenqiang Wei Shutian Zhang Department of Gastroenterology Beijing Friendship HospitalCapital Medical UniversityNational Clinical Research Center for Digestive DiseaseBeijing Digestive Disease CenterBeijing Key Laboratory for Precancerous Lesion of Digestive DiseaseBeijing 100050China Center for Applied Statistics and School of Statistics Renmin University of ChinaBeijing 100872China Statistical Consulting Center Renmin University of ChinaBeijing 100872China National Cancer Center National Clinical Research Center for CancerCancer InstituteChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Department of Gastroenterology Jizhong Energy Fengfeng Group HospitalHandanHebei 056000China RSS and China-Re Life Joint Lab on Public Health and Risk Management Renmin University of ChinaBeijing 100872China

To the Editor:Esophageal cancer,one of the most common cancer types in China,with an estimated 346,633 new cases and 323,600 deaths in 2022,is becoming an increasingly serious clinical and public health problem.^([1])The successful promotion of the self-management strategy has indicated that lifestyle modifications can be valuable in the primary prevention of cancer *** a healthy lifestyle has become a novel strategy for primary prevention and risk reduction in high-risk *** epidemiological studies have identified several lifestyle-related risk factors for esophageal cancer,including smoking and diet.^([2])Each factor can typically explain a modest proportion of cancer ***,when combined,these known risk factors may substantially affect the risk of esophageal ***,some risk factors for esophageal cancer are non-modifiable,including age,low socioeconomic status,and family *** and how these non-modifiable risk factors affect primary cancer prevention by intervening with modifiable risk factors remain unclear.

关键词： esophageal prevention promotion

Clinical features and treatment outcomes of major depressive disorder with genital symptoms

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Chinese Medical Journal 2024年第5期137卷 622-624页

作者： Xiaohui Wu Yuncheng Zhu Ping Sun Shuo wang Zhiguo Wu Jia Huang Lan Cao Yun wang Yousong Su Zhijian Yao Zuowei wang fan wang Yong wang Daihui Peng Jun Chen Yiru fang Department of Clinical Research Center&Division of Mood Disorders Shanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghai 200030China Department of Mood Disorders Shanghai Hongkou Mental Health CenterShanghai 200083China Department of Psychiatry Nanjing Medical University Affiliated Brain HospitalNanjingJiangsu 210029China Department of Psychiatry&Affective Disorders Center Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China CAS Center for Excellence in Brain Science and Intelligence Technology Shanghai 200031China Shanghai Key Laboratory of Psychotic Disorders Shanghai 200118China

To the Editor:Major depressive disorder(MDD)is a mood disorder characterized by complex patterns of emotional,cognitive,and behavioral symptomology and deficits in daily *** symptoms,including a reduction in libido and menstrual disturbances,have been considered to be a classic symptom of MDD for many *** evidence has reached a broad consensus that the incidence of genital symptoms is higher in patients with MDD than in the general population.A systematic review and meta-analysis found a bidirectional association between MDD and genital symptoms,with patients with MDD showing a 50–70%increased risk of developing genital symptoms,while individuals with genital symptoms had a 130–210%increased risk of developing MDD.^([1])As previously reported,50–70%of people with MDD experience sexual dysfunction.^([2])To date,few studies have focused on the comparison of clinical features between patients with MDD with and without genital symptoms,and the longitudinal prognosis.

关键词： symptoms Clinical features

J-family genes redundantly regulate flowering time and increase yield in soybean

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The Crop Journal 2024年第3期12卷 944-949页

作者： Haiyang Li Zheng Chen fan wang Hongli Xiang Shuangrong Liu Chuanjie Gou Chao fang Liyu Chen Tiantian Bu fanjiang Kong Xiaohui Zhao Baohui Liu Xiaoya Lin Guangdong Key Laboratory of Plant Adaptation and Molecular Design/Guangzhou Key Laboratory of Crop Gene Editing/Innovative Center of Molecular Genetics and Evolution School of Life SciencesGuangzhou UniversityGuangzhou 510006GuangdongChina

Soybean(Glycine max)is a short-day crop whose flowering time is regulated by *** longjuvenile trait extends its vegetative phase and increases yield under short-day *** variation in J,the major locus controlling this trait,modulates flowering *** report that the three J-family genes influence soybean flowering time,with the triple mutant Guangzhou Mammoth-2 flowering late under short days by inhibiting transcription of E1-family genes.J-family genes offer promising allelic combinations for breeding.

关键词： Soybean Flowering time Yield J-family genes

人工智能伦理视角下机器非殖民化的批判性设计研究

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南京艺术学院学报（美术与设计） 2024年第2期 122-127页

作者：王帆南京艺术学院设计学院江苏南京210013

文章从机器视觉的诡谲追溯了算法决策是如何在技术系统中编码偏见的,价值失范等伦理问题深植于机器学习驱动的算法社会中,也与人工智能作为采掘业的地球基础设施深度纠缠。笔者思考在计算思维驱动的技术修复解决方案之外,具有非殖民化... 详细信息

文章从机器视觉的诡谲追溯了算法决策是如何在技术系统中编码偏见的,价值失范等伦理问题深植于机器学习驱动的算法社会中,也与人工智能作为采掘业的地球基础设施深度纠缠。笔者思考在计算思维驱动的技术修复解决方案之外,具有非殖民化边界思维的批判性设计是否可以作为替代方案,以当代技术蕴含的隐喻为基础重新想象技术中的默认设置。

关键词：批判性设计人工智能伦理机器学习设计思维

中国参与解决国际热点问题的理念、原则和实践

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外交评论（外交学院学报） 2024年第1期41卷 1-23,I0001,I0002页

作者：王帆外交学院北京100037

党的十八大以来,随着中国综合国力进一步增强,中国在地区热点问题上的参与度和可见度逐步提升。中国始终恪守公平、公正、非暴力的立场和角色,并逐步由参与外交斡旋转向建设性发挥外交调停的作用,其倡议和方案愈益成为解决热点问题的共... 详细信息

党的十八大以来,随着中国综合国力进一步增强,中国在地区热点问题上的参与度和可见度逐步提升。中国始终恪守公平、公正、非暴力的立场和角色,并逐步由参与外交斡旋转向建设性发挥外交调停的作用,其倡议和方案愈益成为解决热点问题的共识。在参与推动朝核、伊核、阿富汗、巴以等重大地区热点问题政治解决的过程中,中国已然积累了诸多丰富经验,提出了“建设性参与”、“标本兼治”和“对话协商”等一系列原则,并采取了以热点问题暂时解决推动根本解决、以非传统安全合作促进传统安全问题解决、促进争议问题解决与地区发展之间联动以及推动地区对话与合作机制建设等实践策略。这些理念、原则和实践丰富和完善了当前的全球治理观念和路径,为世界的安全、稳定与繁荣,为塑造新型国际关系、建构人类命运共同体作出了重要贡献。

关键词：中国外交国际热点问题地区安全全球治理人类命运共同体

迷茫世界的引航灯塔与提质增速的持久动力——2023年国际形势与中国外交

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当代世界 2024年第1期 8-15页

作者：王帆外交学院

当今世界正进入新的动荡变革期。发展与安全问题仍然突出,两场局部战争影响深远,三大地缘政治板块明显活跃。国际格局发生裂变和重组,竞争态势下“小多边”俱乐部加速形成,使“脱钩断链”出现新的表现形式。经济全球化正在遭遇严重冲击... 详细信息

当今世界正进入新的动荡变革期。发展与安全问题仍然突出,两场局部战争影响深远,三大地缘政治板块明显活跃。国际格局发生裂变和重组,竞争态势下“小多边”俱乐部加速形成,使“脱钩断链”出现新的表现形式。经济全球化正在遭遇严重冲击,贸易保护主义和逆全球化浪潮正在导致经济碎片化。欧洲发生“新冷战”的可能性上升,“全球南方”群体性崛起,助推地缘格局版图重组。人类正处在何去何从的十字路口,需要方向性的引领和选择。面对当前世界诸多的不确定性因素和风险挑战,中国秉持和平发展、合作共赢理念,提出一系列创新性的全球治理方案,推动对外工作不断开创新局面,以自身持续发展为世界进步创造新机遇、作出新贡献。

关键词：中国外交国际形势动荡变革期大国关系全球治理

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Efficacy of Huoxue Qianyang Qutan Recipe on essential hypertension:A randomized,double-blind,placebo-controlled trial

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Journal of Integrative Medicine 2024年第4期22卷 484-492页

作者： Jun Xie Yu-long Ma Ming-tai Gui Lei Yao Jian-hua Li Ming-zhu wang Xun-jie Zhou Yi-fan wang Ming-yi Zhao Hui Cao Bo Lu De-yu Fu Department of Cardiology Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghai 200437China Shanghai University of Traditional Chinese Medicine Shanghai 200120China

Background:Hypertension,a prevalent disease,is a significant risk factor for coronary heart *** Qianyang Qutan Recipe (HQQR),a traditional Chinese herbal remedy,has been used for treating hypertension over several ***:This study assesses HQQR’s efficacy for controlling blood pressure among patients with hypertension related to blood stasis,yang hyperactivity and ***,setting,participants and interventions:A randomized controlled trial was conducted at the Yueyang Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine,China,from July 2020 to June *** components of HQQR were identified using thin-layer chromatography and high-performance liquid *** aged18–80 years,exhibiting traditional Chinese medicine syndromes of blood stasis,yang hyperactivity or phlegm,along with grades 1 or 2 hypertension,were randomly categorized into two *** intervention group was given HQQR granules alongside conventional hypertension treatment,while the control group was given placebo granules in addition to conventional treatment for 12 *** outcome measures:The primary outcome was clinic blood pressure,whereas secondary outcomes included metabolic indices (e.g.,homeostasis model assessment of insulin resistance[HOMA-IR],total cholesterol[TC],low-density lipoprotein cholesterol and triglyceride),target organ damage indices (left ventricular mass index and urinary albumin creatinine ratio[UACR]) and inflammation indices(interleukin-6[IL-6]and high-sensitivity C-reactive protein[hs-CRP]).Results:HQQR’s primary components were identified as salvianolic acid B,emodin and ferulic *** the216 participants (108 in each group),compared to the control,the intervention group exhibited significant improvements (P<0.001) in clinic systolic blood pressure ([136.24±7.63]vs[130.06±8.50]mmHg),clinic diastolic blood pressure ([84.34±8.72]vs[80.46±6.05]mmHg),home systoli

关键词： Huoxue Qianyang Qutan Recipe Hypertension Target organ damage Glycolipid metabolism Inflammatory Chinese herbal compound