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Chinese Medical Journal 2012年第1期125卷 123-128页

作者： ZHU Yao-bin FAN Xiang-ming LI Xiao-feng LI Zhi-qiang WANG Qiang SUN Li-zhong LIU Ying-long Pediatric Heart Center Beijing Anzhen HospitalCapital Medical University Beijing 100029 China Pediatric Cardiac Surgery Center Fuwai Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100037 China Cardiovascular Center Beijing Anzhen HospitalCapital Medical University Beijing 100029 China

Background Pediatric patients are susceptible to lung *** lung injury in children often results in high *** liquid ventilation （PLV） has been shown to markedly improve oxygenation and reduce histologic evidence of injury in a number of lung injury *** study was designed to examine the hypothesis that PLV would attenuate the production of local and systemic tumor necrosis factor （TNF）-α in an immature piglet model of acute lung injury induced by oleic acid （OA）.Methods Twelve Chinese immature piglets were induced acute lung injury by *** animals were randomly assigned to two groups of six animals,（1） conventional mechanical ventilation （MV） group and （2） PLV with 10 ml/kg FC-77 *** Compared with MV group,the PLV group had better cardiopulmonary variables （P 〈0.05）.These variables included heart rate,mean blood pressure,blood pH,partial pressure of arterial oxygen （PaO2）,PaO2/inspired O2 fraction （FiO2） and partial pressure of arterial carbon dioxide （PaCO2）.PLV reduced TNF-α levels both in plasma and tissue compared with MV group （P 〈0.05）.Conclusion PLV provides protective effects against TNF-a response in OA-induced acute lung injury in immature piglets.

关键词： acute lung injury animal models partial liquid ventilation

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基于改进隐马尔可夫模型的网络攻击检测方法

通信学报 2010年第3期31卷 95-101页

作者：杨晓峰孙明明胡雪蕾杨静宇南京理工大学计算机系江苏南京210094

提出了一种基于改进隐马尔可夫模型的网络攻击检测方法。正常的网络行为符合一定的语法规则,异常的行为会偏离正常的语法规则。通过对正常行为样本的学习得到的基于隐马尔可夫模型的语法可以根据网络行为和语法的符合程度有效地检测正... 详细信息

提出了一种基于改进隐马尔可夫模型的网络攻击检测方法。正常的网络行为符合一定的语法规则,异常的行为会偏离正常的语法规则。通过对正常行为样本的学习得到的基于隐马尔可夫模型的语法可以根据网络行为和语法的符合程度有效地检测正常行为和攻击行为。在基于现实数据的实验测试中,得到了比较好的检测性能。

关键词：网络安全网络攻击入侵检测隐马尔可夫模型语法推断

The effect of single-operation-hole thoracoscopic surgery on elderly solitary pulmonary nodules and its effects on lung function and prognosis

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Journal of Hainan Medical University 2018年第23期24卷 71-75页

作者： feng Luo ming-Song Wang Shan-Wei Lu Jie Li Huai-Yang Xu Department of thoracic surgery Chongming Branch Hospital of Xinhua Hospital Affiliated to Shanghai Jiaotong University School of MedicineShanghai202150China Department of cardiothoracic surgery Xinhua Hospital Affiliated to Shanghai Jiaotong University School of MedicineShanghai200092China

Objective:To investigate the effect of single-operation-hole thoracoscopic surgery on elderly solitary pulmonary nodules and its effects on lung function and ***:64 patients with solitary pulmonary nodules admitted to our hospital were selected. According to the different surgical treatment methods, they were divided into the study group and the control group, each group with 32 cases. The study group was treated with single-operation-hole thoracoscopic pulmonary nodule resection, and the control group was treated with conventional multi-operation-holes thoracoscopic pulmonary nodule resection. The clinical efficacy of the two groups was compared. Results: The postoperative drainage time, intraoperative blood loss, hospitalization time, postoperative drainage volume and hospitalization cost of the study group were significantly better than those of the control group (P0.05). There was no difference in lung function between the two groups before operation (P>0.05). Compared with the control group, the lung function indexes of the postoperative study group were significantly improved (P0.05). The VAS scores of the study group were significantly lower than those of the control group on the 1st and 3rd day after operation (P0.05), but the overall health status, physiological feature, physiological function, physical pain and energy of the patients in the study group after treatment were significantly higher than those in the control group (P<0.05), but there was no significant difference in social fun

关键词： Single-operation-hole thoracoscopic surgery Solitary pulmonary nodules Pulmonary function Prognosis

超声波散射式颗粒测量及其测量结果单值性的分析

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计量学报 2006年第2期27卷 179-182页

作者：明廷锋朴甲哲张永祥海军工程大学船舶与动力工程学院湖北武汉430033

提出了一种超声波散射式颗粒测量方法,论述了该技术应用的理论基础,并在详细分析其测量原理基础上,指出了在单频率换能器和单散射角下进行颗粒测量时存在着测量结果多值性的可能。给出了解决这一关键技术问题所采取的可能方案和措施。

关键词：计量学颗粒测量声散射超声波聚焦换能器

Serological and molecular study of hepatitis E virus among illegal blood donors

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World Journal of Gastroenterology 2012年第9期18卷 986-990页

作者： Xian-feng Cheng Yu-feng Wen ming Zhu Sheng-Wei Zhan Chen Dong Ke-Xia Xiang Xiao-Bing Xia Gang Wang Ling-Fei Han Ma AnshanCenter for Disease Control and Prevention Maanshan 243000Anhui ProvinceChina Department of Preventive Medi-cine Wannan Medical CollegeWuhu 241320Anhui ProvinceChina Department of Microbiology and Immunology School of MedicineSoutheast UniversityNanjing 210096Ji-angsu ProvinceChina Department of Clinical Laboratory the Forth Peo-ple's Hospital of MaanshanMaanshan 243000Anhui ProvinceChina

AIM： To investigate the seroprevalence and molecular characteristics of hepatitis E virus （HEV） in the illegal blood donors （IBDs） of central China in the early 1990s.

关键词： Molecular Sero-epidemiology Hepatitis E He-patitis E virus Commercial blood donors

人类学仪式研究的空间转向——以瑶族送鬼仪式中人、自然与宇宙的关系建构为例

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广西师范大学学报（哲学社会科学版） 2013年第1期49卷 45-50页

作者：冯智明广西师范大学文学院广西桂林541004

20世纪70年代以来,西方社会科学界逐渐掀起"空间转向"研究思潮。瑶族"送鬼"仪式中体现的空间观念及其建构表明,人类学仪式研究的"空间转向"为仪式及空间本身的研究提供了一个崭新的范式,促进仪式研究从仪式本体研究、功能论和象征论等... 详细信息

20世纪70年代以来,西方社会科学界逐渐掀起"空间转向"研究思潮。瑶族"送鬼"仪式中体现的空间观念及其建构表明,人类学仪式研究的"空间转向"为仪式及空间本身的研究提供了一个崭新的范式,促进仪式研究从仪式本体研究、功能论和象征论等传统理论模式向人类身体、空间感知和建构理论解释的转变,更加注重仪式与人类自身及其认知、知识体系的关系。这一转向对于南方山地民族来说,具有更加独特的研究意义。

关键词：仪式空间转向瑶族

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非均匀地基与均匀地基解答之间的相似关系

岩土力学 2013年第12期34卷 3372-3376页

作者：周凤玺赖远明米海珍兰州理工大学土木工程学院兰州730050 中国科学院寒区旱区环境与工程研究所兰州730000

考虑材料特性沿厚度按幂律梯度变化的非均匀地基,研究了在竖向和水平线荷载作用下,非均匀弹性地基与均匀弹性地基解答之间的转换关系。基于应变分量之间的变形协调条件,获得了非均匀弹性半空间在线荷载作用下的应力分量和应变分量的解... 详细信息

考虑材料特性沿厚度按幂律梯度变化的非均匀地基,研究了在竖向和水平线荷载作用下,非均匀弹性地基与均匀弹性地基解答之间的转换关系。基于应变分量之间的变形协调条件,获得了非均匀弹性半空间在线荷载作用下的应力分量和应变分量的解析表达式,通过比较非均匀地基和均匀地基的解答,发现了它们之间的线性相关性,可将非均匀弹性地基在均布线荷载作用下的解答用相同条件下的均匀地基解答线性表示,得到了解答之间的相似转换系数的表达式,该系数集中反映了地基物理力学特性的非均匀程度。因此,借助于均匀地基的经典解答,可将非均匀地基问题的求解转化为对相似转换系数的计算,从而使得问题得以简化。为了方便应用,采用曲线图的形式给出了不同非均匀指数情形下的相似转换系数。

关键词：非均匀地基相似转换解析解弹性半空间

Relationship between interleukin-6 polymorphism and susceptibility to chronic hepatitis B virus infection

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World Journal of Gastroenterology 2013年第40期19卷 6888-6893页

作者： Xiao-Miao Zhao Yu-feng Gao Qin Zhou Fa-ming Pan Xu Li Department of Infectious Diseases The First Affiliated Hospital of Anhui Medical University Department of Hepatopathy The Second Affiliated Hospital of Anhui Medical University Department of Epidemiology and Biostatistics School of Public HealthAnhui Medical University

AIM:To identify the relationship between tag single nucleotide polymorphisms(tag SNPs) of interleukin-6(IL-6) gene and susceptibility to chronic hepatitis B virus(HBV) infection in a Han Chinese ***:We performed a case-control study of501 Chinese patients with chronic HBV infection and301 self-limiting HBV-infected individuals as *** DNA was isolated from the whole blood of all subjects using phenol/chloroform with MaXtract highdensity tubes. Tag SNPs were identified using genotype data from the panel(Han Chinese in Beijing) of the phase II HapMap Project. Four tag SNPs in IL-6(rs17147230A/T,rs2066992G/T,rs2069837A/G and rs2069852A/G) were genotyped by the Multiplex Snapshot technique. The genotype and allele frequencies were calculated and ***:Five haplotypes were involved in the analysis,with frequencies higher than 0.03. One of the haplotypes,TTAA,was significantly different between the two groups. Overall haplotype P values were:ATAA,P = 0.605,OR(95%CI) = 1.056(0.860-1.297); TGAG,P = 0.385,OR(95%CI) = 1.179(0.813-1.709); TGGG,P = 0.549,OR(95%CI) = 1.087(0.827-1.429); TTAA,P = 0.004,OR(95%CI) = 0.655(0.491-0.873); TTAG,P = 0.266,OR(95%CI) = 1.272(0.832-1.944). However,the four SNPs showed no significant genotype/allele associations with susceptibility to chronic HBV infection. Overall allele P values were:rs17147230,P = 0.696,OR(95%CI) = 1.041(0.850-1.276); rs2066992,P = 0.460,OR(95%CI)= 1.090(0.868-1.369); rs2069837,P = 0.898,OR(95%CI) = 0.983(0.759-1.274); rs2069852,P = 0.165,OR(95%CI) = 0.859(0.693-1.064). Overall genotype P values were:rs17147230,P = 0.625; rs2066992,P= 0.500; rs2069837,P = 0.853; and rs2069852,P =***:The four tag SNPs of IL-6 gene may be associated with susceptibility to chronic HBV infection in the Han Chinese population.

关键词： Chronic hepatitis B virus infection Interleukin-6 Single nucleotide polymorphism Genetic susceptibility Haplotype

基于Hsia算法的Hammerstein模型辨识

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系统仿真学报 2007年第23期19卷 5373-5375页

作者：沈同全孙逢春程夕明北京理工大学机械与车辆工程学院北京理工大学机械与车辆工程学院北京100081

针对采用广义最小二乘法(GLS)辨识Hammerstein模型时反复滤波,计算效率不高的问题,提出了利用Hsia算法进行Hammerstein模型辨识的策略。该法不需滤波,克服最小二乘解有偏性的同时,消除了Hammerstein模型中非线性增益的阶次对计算效率降... 详细信息

针对采用广义最小二乘法(GLS)辨识Hammerstein模型时反复滤波,计算效率不高的问题,提出了利用Hsia算法进行Hammerstein模型辨识的策略。该法不需滤波,克服最小二乘解有偏性的同时,消除了Hammerstein模型中非线性增益的阶次对计算效率降低的作用,编程简单,计算快速。仿真及试验研究证明该法省时明显,值得推广。

关键词：非线性动态过程 Hammerstein模型 Hsia算法系统辨识

A Retrospective Study of General Anesthesia Combined with Epidural Block used in 3858 Patients Underwent Hepatectomy

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麻醉与监护论坛 2011年第6期18卷 421-424页

作者： Li-Qun Yang Wei-feng Yu Yu-ming Sun Feixiang Wu Kunming Tao Department of Anesthesiology Eastern Hepatobiliary Surgery Hospita Affiliated to the Second Military MedicalUniversity Shanghai 200438China

Aim: Most of patient undergoing hepatic surgery have a long-term cirrhosis history and combined with pathophysiologic disorders, a better understanding of anesthetic character about hepatic surgery is perhaps important and beneficial. The objective of this study is to investigate the merit and defect of general anesthesia combined with epidual block used inpatients undergoing hepatectomy. Methods: The Patients were admitted from 2004 to 2009 in Eastern Hepatobiliary Surgery Hospital in Shanghai, China, and all patients were performed hepactotomy, totally 4058 patients" anethstetic records and postoperative data were analyzed, including patients underwent general combined with epidural (CGEA, n=3858), general anesthesia group (G, n=100) and epidural block group (E, n=100). The intraoperative stability of vital signs, consumption of intravenous anesthetics/analgesics, muscle relaxants and cardiovascular drugs were compared. During the postoperative awake phase, the extubation time, pain relief time and awake related complications in 3 groups were also compared. Results: General anesthesia combined with epidural block group influenced patient's heart rate and blood pressure, but using low dose of cardiovascular activator (ephedrine) can rectify this effect greatly. CGEA can markedly reduce needs of atracurium, fentanyl and inhaled anesthetics. In awake phase, General anesthesia combined with epidural block group can awake and extube earlier with lower dysphoria,uroschesis and mantains longer- term pain relief than that of other groups. Conclusions: General anesthesia combined with epidural block was safe and reasonable for hepatectomy compared with general or epidural anesthesia. The side effects of the technique were hypotension bradycardia and to light general anesthesia, which can result in awareness during surgery, and also, the use of CGEA in hepatic surgery is increasing because of the favorable recovery characteristics that facilitate early hospital discharge.

关键词：外科手术学麻醉学临床监护