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Incidence and prognosis of olfactory and gustatory dysfunctions related to SARS-CoV-2.Omicron strain infection in china:A national multicenter survey of 35,566 individuals

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第2期10卷 113-120页

作者： Meng-Fan Liu Rui-Xia Ma Xian-Bao Cao Hua Zhang Shui-Hong Zhou Wei-Hong Jiang Yan Jiang Jing-wu Sun Qin-Tai yang Xue-Zhong Li Ya-Nan Sun Li Shi Min Wang Xi-Cheng Song fu-Quan Chen Xiao-Shu Zhang Hong-Quan Wei Shao-Qing Yu Dong-Dong Zhu Luo Ba Zhi-Wei Cao Xu-Ping Xiao Xin Wei Zhi-Hong Lin {2.-Hong Chen Chun-Guang Shan Guang-Ke Wang Jing Ye Shen-Hong Qu Chang-Qing Zhao Zhen-Lin Wang Hua-Bin Li {2. Liu Xiao-Bo Cui Sheng-Nan Ye Zheng Liu Yu Xu Xiao Cai Wei Huang Ru-Xin Zhang Yu-Lin Zhao Guo-Dong Yu Guang-Gang Shi Mei-Ping Lu yang Shen Yu-Tong Zhao Jia-Hong Pei Shao-Bing Xie Long-Gang Yu Ye-Hai Liu Shao-Wei Gu Yu-Cheng yang Lei Cheng Jian-{2. liu Graduate School of Beijing university of Chinese Medicine BeijingChina department of Otorhinolaryngology Head and Neck Surgery China-Japan Friendship HospitalBeijingChina department of Otorhinolaryngology Head and Neck Surgery The First People's Hospital of YinchuanYinchuanChina department of Otorhinolaryngology The First People's Hospital of Yunnan ProvinceKunmingChina department of Otorhinolaryngology The First Affiliated Hospital of Xinjiang Medical UniversityUrumqiChina department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of Zhejiang University School of MedicineHangzhouChina department of Otorhinolaryngology Head and Neck Surgery Xiangya Hospital Central South UniversityChangshaChina department of Otorhinolaryngology Head and Neck Surgery The Affiliated Hospital of Qingdao UniversityQingdaoChina department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of USTCHefeiChina department of Otorhinolaryngology Head and Neck Surgery The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouChina department of Otorhinolaryngology Head and Neck Surgery Qilu Hospital of Shandong UniversityJinanChina department of Otorhinolaryngology Head and Neck Surgery The Second Affiliated Hospital of Harbin Medical UniversityHarbinChina department of Otolaryngology The Second Hospital of Shandong UniversityShandong UniversityJinanChina department of Otorhinolaryngology Head and Neck Surgery Peking University People's HospitalBeijingChina department of Otorhinolaryngology Head and Neck Surgery Yantai Yuhuangding HospitalQingdao UniversityYantaiChina department of Otorhinolaryngology Head and Neck Surgery Xijing HospitalThe Fourth Military Medical UniversityXi'anChina Gansu Provincial Center for Disease Control and Prevention LanzhouChina department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of China Medical UniversityShenyangChina department of Otorhinolaryngology Head and Neck Surgery Tongji Hospit

Objective:This cross-sectional study aimed to determine the epidemiology of olfactory and gustatory dysfunctions related to COVID-19 in ***:This study was conducted by 45 tertiary Grade-A hospitals in *** and offline questionnaire data were obtained from patients infected with COVID-19 between December 2.,2.2.,and February 2.,*** collected information included basic demographics,medical history,smoking and drinking history,vaccination history,changes in olfactory and gustatory functions before and after infection,and other postinfection symptoms,as well as the duration and improvement status of olfactory and gustatory ***:Complete questionnaires were obtained from 35,566 *** overall incidence of olfactory and taste dysfunction was 67.75%.Being female or being a cigarette smoker increased the likelihood of developing olfactory and taste *** received four doses of the vaccine or having good oral health or being a alcohol drinker decreased the risk of such *** infection,the average olfactory and taste VAS scores were 8.41 and 8.51,respectively;after infection,they decreased to 3.69 and 4.2. and recovered to 5.83.and 6.55 by the time of the *** median duration of dysosmia and dysgeusia was 15 and 12.days,respectively,with 0.5%of patients having symptoms lasting for more than 2. *** overall self-reported improvement rate was 59.16%.Recovery was higher in males,never smokers,those who received two or three vaccine doses,and those that had never experienced dental health issues,or chronic accompanying ***:The incidence of dysosmia and dysgeusia following infection with the SARS-CoV-2.virus is high in *** and prognosis are influenced by several factors,including sex,SARS-CoV-2.vaccination,history of head-facial trauma,nasal and oral health status,smoking and drinking history,and the persistence of accompanying symptoms.

关键词： epidemiologic studies incidence olfactory disorders prognosis SARS-CoV-2 taste disorders

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CD98-induced CD147 signaling stabilizes the Foxp3 protein to maintain tissue homeostasis

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Cellular & Molecular Immunology 2021年第12期18卷 2618-2631页

作者： JieJie Geng Ruo Chen feng-fan yang Peng Lin Yu-meng Zhu Xianghui {2. Ke Wang Zhuan feng Jiao wu Hai Zhang Qi-jing Li Zhi-Nan Chen Ping Zhu department of Clinical Immunology Xijing HospitalFourth Military Medical UniversityXi’anP.R.China National Translational Science Center for Molecular Medicine&department of Cell Biology Fourth Military Medical UniversityXi’anP.R.China department of Immunology Duke University Medical CenterDurhamNCUSA

Regulatory T cell(Treg)stability is necessary for the proper control of immune activity and tissue ***,it remains unclear whether Treg stability must be continually reinforced or is established during development under physiological ***3 has been characterized as a central mediator of the genetic program that governs Treg ***,we demonstrate that to maintain Foxp3 protein expression,Tregs require cell-to-cell contact,which is mediated by the CD147-CD98 *** Tregs are produced,CD147,which is expressed on their surface,is stimulated by CD98,which is widely expressed in the physiological *** a result,CD147’s intracellular domain binds to CDK2.and retains it near the membrane,leading to Foxp3 dephosphorylation and the prevention of Foxp3 *** addition,the optimal distribution of Foxp3+Tregs under both pathological and physiological conditions depends on CD98 ***,our study provides direct evidence that Foxp3-dependent Treg stability is reinforced in the periphery by the interaction between CD147 and CD98 in the surrounding *** importantly,Tregs with high CD147 expression effectively inhibit inflammatory responses and maintain Foxp3 stability,which has guiding significance for the application of Tregs in immunotherapy.

关键词： Treg Stability CD147 CD98 CDK2 Immune therapy

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土壤农业利用适宜性评价方法与规范编制说明

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土壤通报 2024年第5期55卷 1201-1204页

作者：吴克宁康龙李潇陈章全赵玉国毕如田赵华甫冯喆中国地质大学(北京)土地科学技术学院北京100083 农业农村部农田建设管理司北京100125 国务院第三次全国土壤普查领导小组办公室北京100125 中国科学院南京土壤研究所土壤与农业可持续发展国家重点实验室江苏南京210008 山西农业大学资源环境学院山西太古030801

土壤农业利用适宜性评价是第三次全国土壤普查工作的重要内容之一。为确保评价工作的科学有效性,保障土壤普查工作全面开展的顺畅性,文章对土壤农业利用适宜性评价的工作内容和评价方法进行了介绍,对土壤农业利用适宜性评价技术规范编... 详细信息

土壤农业利用适宜性评价是第三次全国土壤普查工作的重要内容之一。为确保评价工作的科学有效性,保障土壤普查工作全面开展的顺畅性,文章对土壤农业利用适宜性评价的工作内容和评价方法进行了介绍,对土壤农业利用适宜性评价技术规范编制过程中的重要修改内容进行了说明。

关键词：第三次全国土壤普查土壤调查与评价农业利用适宜性评价

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Rejuvenated metallic glass strips produced via twin-roll casting

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Journal of Materials Science & Technology 2020年第3期38卷 73-79页

作者： Long Zhang Yi wu Shidong feng Wen Li Hongwei Zhang Huameng fu Hong Li Zhengwang Zhu Haifeng Zhang Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China Shenyang Ligong university Shenyang 110159China Advanced Manufacturing Technology Research Centre Department of Industrial and Systems EngineeringThe Hong Kong Polytechnic University999077Hong KongChina State Key Laboratory of Metastable Materials Science and Technology Yanshan UniversityQinhuangdao 066004China

The energy state and atomic level structure of metallic glasses(MGs)are very sensitive to their cooling rates,and a lower cooling rate generally causes a lower energy and more relaxed state of *** this work,the Zr41.2.Ti13.8 Cu12.5 Ni10 Be2..5(Vit.1)ribbons with a thickness of 40μm and 110μm and the strips with a thickness of 32.μm and 490μm were produced by single-roll melt spinning and twin-roll casting,*** increase in thickness of either ribbons or strips results in a lower energy state with a smaller relaxation enthalpy,a lower content of free volume,and a higher *** the cooling rate of the twin-roll produced 32.μm-thick strip is almost one magnitude lower than that of the single-roll produced 110μm-thick ribbon,the former,however,possesses a rejuvenated energy state as compared to the *** dynamics simulations reveal that the squeezing force during twin-roll casting affects the evolution of connection types of clusters,and the 2.atom and 4-atom connections are prone to be retained,which results in a higher energy state of *** a rejuvenation process during twin-roll casting can overwhelm the relaxation process caused by the lower cooling ***,twin-roll casting is not only a method being capable for producing strips with a large thickness,but also prone to obtain a high energy state of the MG strip.

关键词： Metallic glass Metallic glass strip Twin-roll casting Rejuvenation Cluster connection

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Side-chains Engineering of Conjugated Polymers toward Additive-free Non-fullerene Organic Solar Cells

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Chinese Journal of Polymer Science 2021年第1期39卷 43-50,I0005页

作者： feng Liu Dan Wang Jun-Yu Li Cheng-Yi Xiao Yong-Gang wu Wei-Wei Li Guang-Sheng fu College of Physics Science&Technology Hebei UniversityBaoding 071002China Beijing Advanced Innovation Center for Soft Matter Science and Engineering&State Key Laboratory of Organic-Inorganic Composites Beijing University of Chemical TechnologyBeijing 100029China

Side-chain engineering plays a significant role in the design of conjugated materials. In this work, a series of conjugated polymers PBDB-T-R with functionalized groups at the end of side units were developed as electron donor for organic solar cells(OSCs). The donor polymers PBDB-T-I and PBDB-T-OAc with iodine and acetate end groups exhibited similar absorption and energy levels, but showed much improved PCEs in OSCs compared to the polymer PBDB-T-H without substitutions at the end groups. Additionally, we found that PBDB-T-I and PBDB-T-OAc based cells exhibited optimized performance when using chloroform as solution-processed solvent without any additives. These results indicate that these conjugated polymers can act as self-additive to fabricate photoactive layers via solution process in OSCs.

关键词： Organic solar cells Non-fullerene End group Additive Crystallinity

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Synthesis,Structural Characterization,Fluorescence Properties and Herbicidal Activity of Bis(substituted salicylaldehyde)Carbohydrazide Dibutyltin Complexes

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Chinese Journal of Structural Chemistry 2021年第12期40卷 1639-1646,1553页

作者： feng Yong-Lan JIANG wu-Jiu ZHANG fu-Xing KUANG Dai-Zhi Key Laboratory of functional Metal-organic Compounds of Hunan Province Key Laboratory of Functional Organometallic Materials of College of Hunan ProvinceDepartment of Chemistry and Material ScienceHengyang Normal UniversityHengyangHunan 421008China

A series of dibutyltin complexes,(Bu_(2.Sn)_(2.L,[(Bu_(2.Sn)_(2.L]3.and H_(2.LSnBu_(2.,were synthesized by microwave-assisted methanolic solvothermal method,where H4L is[_(2.-(OH)-R-ArCH=NNH]_(2.CX,and X=O,R=4-NEt_(2.(Tl),5-Br(T_(2.);X=S,R=H(T3);R=5-Br(T4).Their structures were characterized by elemental analysis,IR and(^(1)H,^(13)C)-NMR *** molecular structure of T_(2. was confirmed by X-ray *** crystal of T_(2. belongs to monoclinic system,space group ***-coordinated distorted triangular bipyramids and six-coordinated distorted octahedral configurations were formed by the coordination of oxygen and nitrogen atoms of ligand with two dibutyltins,thus forming a trimeric hexanuclear butyltin complex by the cross coordination of three units(Bu_(2.Sn)_(2.L with enol *** T_(2. and T4 exhibit fluorescence emission in DMF solvents and DMF-water *** fluorescence intensity of T_(2.-DMF-H_(2.0 system decreases almost linearly with the increase of water volume fraction(WVF).The aggregation fluorescence enhancement effect of T4-DMF-H_(2.0 solution system increases with the increase of WVF at the range of 0-_(2.0%*** WVF is more than _(2.0%,the fluorescence intensity decreases with the increase of *** addition,T1〜T4 have broad growth activities on target plants,such as Portulaca oleracea L.,Amaranthus spinosus L.,Cassia tora L.,Brassica campestris *** *** Tsen et Lee,and Amaranthus tricolor L.,and can be used as a candidate herbicide for further research.

关键词： bis(substituted salicylaldehyde)carbohydrazide dibutyltin fluorescence properties herbicidal activity

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Gene Transcription Profile in Mice Vaccinated with Ultraviolet-attenuated Cercariae of Schistosoma japonicum Reveals Molecules Contributing to Elevated IFN-γ Levels

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Acta Biochimica et Biophysica Sinica 2005年第4期37卷 254-264页

作者： Xiang ZHU Zhao-Song ZHANG Min-Jun JI Hai-Wei wu Yong WANG Xiao-Ping CAI Lei ZHANG Shu-Ying HU Lin-Lin fu feng LIU Chuan SU Guan-Ling wu {2. of Pathogenic Biology,Nanjing Medical {2..Nanjing 2.002..china departmentofPathogenicBiology NanjingMedicalUniversityNanjing210029China

Vaccination with ultraviolet-attenuated cercariae of Schistosoma japonicum induced protectiveimmunity against challenge infection in experimental animal *** preliminary study on the transcrip-tion levels of IFN-γ and IL-4 in splenic CD4~+ T cells revealed that attenuated cercariae elicited predomi-nantly a Th1 response in mice at the early stage,whereas normal cercariae stimulated primarily Th2.dependent *** analysis on the gene profile of the skin-draining lymph nodes demonstratedthat the levels of IFN-γ were significantly higher in vaccinated mice than those in infected mice at day 4,7and 14 post-vaccination or ***,for IL-12.and IL-4,the potent inducers of Th1 andTh2.responses,respectively,as well as IL-10,there were no differences over the course of the experimentbetween the infected and vaccinated *** explore the underlying factors that may potentially contributeto elevated IFN-γ in vaccinated mice,the mRNA profiles of the skin-draining lymph nodes at day 4 post-exposure were compared using oligonucleotide *** the 847 probe sets with increased signalvalues,we focused on chemokines,cytokines and relevant receptors,which were validated by semi-quantitativeRT-PCR,A comprehensive understanding of the immune mechanisms of attenuated cercariae-inducedprotection may contribute to developing efficient vaccination strategies against ***,especiallyduring the early stare of infection.

关键词： Schistosoma japonicum attenuated cercariae oligonucleotide microarray IFN-γ chemokines

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Impact of intravenous dexmedetomidine on postoperative bowel movement recovery after laparoscopic nephrectomy: A consortprospective, randomized, controlled trial

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World Journal of Clinical Cases 2021年第26期9卷 7762-7771页

作者： Shan-Shan Huang fu-Xi Song Shao-Zhong yang Shuai Hu Lian-Ying Zhao Shu-Qin Wang Qi wu Xin Liu {2. Qi department of Anesthesiology Qilu HospitalCheeloo College of MedicineShandong UniversityJinan 250012Shandong ProvinceChina department of Anesthesiology The Second HospitalCheeloo College of MedicineShandong UniversityJinan 250033Shandong ProvinceChina

BACKGROUND Postoperative ileus is a frequent postoperative complication,especially after abdominal *** excitation is the primary factor for postoperative *** activation becomes increased by surgical stress,postoperative pain,and ***(DEX)can inhibit sympathetic nerve activity,inflammation,and *** To observe whether DEX promotes bowel movements in patients after laparoscopic *** One hundred and twenty patients undergoing laparoscopic nephrectomy were assigned to three groups:C(normal saline infusion),D1(DEX 0.02.g/kg/h),and D2.DEX 0.04μg/kg/h).The primary outcomes were the recorded times to first flatus,defecation,and eating after *** secondary outcomes were postoperative pain,assessed using the numerical rating scale(NRS),adverse effects,and the duration of the postoperative hospital *** The times to first flatus,defecation,and eating in groups D1 and D2.were significantly shorter than those in group C(P2. h after surgery were significantly lower in groups D1 and D2.than in group C(P0.05).CONCLUSION Postoperative infusion of DEX at 0.04μg/kg/h facilitates bowel movements in patients undergoing laparoscopic nephrectomy.

关键词： Dexmedetomidine Bowel movement Recovery Flatus Postoperative

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Color-electric conductivity in a viscous quark-gluon plasma

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Chinese Physics C 2021年第5期45卷 157-165页

作者： Bing-feng Jiang Shao-wu Shi De-fu Hou Jia-rong Li Center for Theoretical Physics and department of Physics Hubei Minzu UniversityEnshi 445000China Key Laboratory of Quark and Lepton Physics(MOE)and Institute of Particle Physics Central China Normal UniversityWuhan 430079China

Several different transport processes, such as heat, momentum, and charge transports, may occur simultaneously in a thermal plasma system. The corresponding transport coefficients are heat conductivity, shear viscosity, and electric conductivity. In the present study, we investigate the color-electric conductivity of the quark-gluon plasma(QGP) in the presence of shear viscosity, focusing on the connection between the charge transport and momentum transport. To achieve this goal, we solve the viscous chromohydrodynamic equations obtained from the QGP kinetic theory associated with the distribution function modified by shear viscosity. According to the solved color fluctuations of hydrodynamic quantities, we obtain the induced color current through which the color-electric conductivity is derived. Numerical analysis shows that the conductivity properties of the QGP are mainly demonstrated by the longitudinal part of the color-electric conductivity. Shear viscosity has an appreciable impact on real and imaginary parts of the color-electric conductivity in some frequency regions.

关键词： color-electric conductivity quark-gluon plasma shear viscosity viscous chromohydro-dynamics

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Two new kaempferol glycosides from the seeds of Camellia semiserrata Chi

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Chinese Chemical Letters 2011年第7期22卷 835-838页

作者： Ling Tang Xiao Juan wu Bao Min feng Li Ying Shi Xue Yan fu Yong Qi Wang Mei feng Liu College of Bioengineering Dalian University Dalian 116622 China Liaoning Key Laboratory of Bioorganic Chemistry Dalian University Dalian 116622 China Pharmaceutical department Ningxia Medical University Yinchuan 750004 China School of Chemistry and Chemical Engineering South China University of Technology Guangzhou 510640 China

Two new acetylated kaempferol glycosides were isolated from the seeds of Camellia semiserrata Chi, their structures were elucidated as kaempferol-3-O-[（3-O-acetyl）-a-L-rhamnopyranosyl（1 →3）（4-O-acetyl）-α-L-rhamnopyranosyl（1→ 6）-β-D-glucopyranoside] （1） and kaempferol-3-O-[（2.O-acetyl）-α-L-rhamnopyranosyl （1 →3）（4-O-acetyl）-α-L-rhamnopyranosyl（1 →6）-β-D- gluco-pyranoside] （2. by spectral experiments （including ESI-MS, 1D- and 2.-NMR）..

关键词： Camellia semiserrata Chi Kaempferol glycosides Theaceae

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