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Lump and travelling wave solutions of a(3+1)-dimensional nonlinear evolution equation

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Journal of Ocean Engineering and Science 2024年第2期9卷 164-172页

作者： Kalim u.Tariq Raja Nadir Tufail Department of Mathematics Mirpur University of Science and TechnologyMirpurAJK 10250Pakistan

In this paper,the(3+1)-dimensional nonlinear evolution equation is studied *** bilinear form of given model is achieved by using the Hirota bilinear *** a result,the lump waves and col-lisions between lumps and periodic waves,the collision among lump wave and single,double-kink soliton solutions as well as the collision between lump,periodic,and single,double-kink soliton solutions for the given model are ***,some new traveling wave solutions are developed by applying the exp(−φ(ξ))expansion *** 3D,2D and contours plots are drawn to demonstrate the nature of the nonlinear model for setting appropriate set of *** a result,a collection of bright,dark,periodic,rational function and elliptic function solutions are *** applied strategies appear to be more powerful and efficient approaches to construct some new traveling wave structures for various contemporary models of recent era.

关键词： The Hirota bilinear method Lump wave solution Travelling wave solution Exp(−φ(ξ))expansion technique

Latest Carboniferous-Early Permian Rifting of the Northern Gondwanan Margin and the Opening of the Northern Neotethys: New Evidence from the Carboniferous and Permian foraminiferal Assemblages from the Beyşehir-Hoyran Nappes, Central Taurides(Southern Turkey)

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Journal of Earth Science 2024年第2期35卷 394-415页

作者： Cengiz Okuyucu u.Kagan Tekin Cagri Guzgun Kaan Sayit Department of Geological Engineering Konya Technical UniversityKonya42250Turkey Department of Geological Engineering Hacettepe UniversityAnkara06800Turkey Department of Geological Engineering Middle East Technical UniversityAnkara06800Turkey

The Beyşehir-Hoyran Nappes,one of the tectonostratigraphic units of the Taurides,are thought to be originated from the Izmir-Ankara Ocean(northern branch of Neotethys).In this study,Late Paleozoic rock units from the blocks of Beyşehir-Hoyran Nappes were studied in detail using foraminiferal assemblages in two different locations from the southwest of Karaman City(southern Turkey).In both places,blocks/slices and pebbles of various origins are embedded within a highly sheared matrix of Late Cretaceous Age,and the whole unit can be regarded as a sedimentary mé*** ages of the blocks from the southwest of Karaman City range from the Late Serpukhovian(Late Mississippian)to Late Capitanian(Middle Permian)with some depositional breaks(e.g.,Bashkirian,Kasimovian).Combined with the previous data from the Mersin Mélange,which also include the remnants of the Beyşehir-Hoyran Nappes,our new findings suggest that a shallowing-upward sequence,characterized by a shallow water environment with foraminifera-bearing limestones,was deposited over the Tournaisian pelagic sequence in the Beyşehir-Hoyran Nappes till the Early Moscovian(Early Middle Pennsylvanian).This shallowing-upward sequence in the Beyşehir-Hoyran Nappes could be related to the Late Paleozoic Glaciation on the Gondwana supercontinent(Glacial Ⅱ),which resulted in a sea-level drop and deposition of platform carbonates during the Viséan–Early Moscovian(Middle Mississippian to Early Middle Pennsylvanian)time *** absence of the main part of the Middle-upper Pennsylvanian deposits(continental phase during the Middle Moscovian–Middle Gzhelian)in the Beyşehir-Hoyran Nappes can be mainly attributed to the occurrence of a mantle plume and partially to the effect of Late Paleozoic Gondwanan Glaciation(Glacial Ⅲ).Progressive uplifting by the buoyant mantle plume material has resulted in rifting at the center of the basin where the Beyşehir-Hoyran Nappes have *** rifting process led to tectonic destabiliz

关键词： foraminifera Carboniferous and Permian Beyşehir-Hoyran Nappes plume rifting Neotethys paleontology

In search of a pan-coronavirus vaccine:next-generation vaccine design and immune mechanisms

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Cellular & Molecular Immunology 2024年第2期21卷 103-118页

作者： S.Cankat M.u.Demael L.Swadling Division of Infection and Immunity Institute of Immunity and TransplantationUniversity College LondonPears BuildingLondon NW32PPUK

Members of the coronaviridae family are endemic to human populations and have caused several epidemics and pandemics in recent *** this review,we will discuss the feasibility of and progress toward the ultimate goal of creating a pan-coronavirus vaccine that can protect against infection and disease by all members of the coronavirus *** will detail the unmet clinical need associated with the continued transmission of SARS-CoV-2,MERS-CoV and the four seasonal coronaviruses(HCoV-OC43,NL63,HKu1 and 229E)in humans and the potential for future zoonotic *** will highlight how first-generation SARS-CoV-2 vaccines and natural history studies have greatly increased our understanding of effective antiviral immunity to coronaviruses and have informed next-generation vaccine *** will then consider the ideal properties of a pan-coronavirus vaccine and propose a blueprint for the type of immunity that may offer ***,we will describe a subset of the diverse technologies and novel approaches being pursued with the goal of developing broadly or universally protective vaccines for coronaviruses.

关键词： Vaccine Coronavirus Cross-reactive immunity Cross-protection universal

On some new travelling wave structures to the(3+1)-dimensional Boiti-Leon-Manna-Pempinelli model

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Journal of Ocean Engineering and Science 2024年第2期9卷 99-111页

作者： Kalim u.Tariq Ahmet Bekir Muhammad Zubair Department of Mathematics Mirpur University of Science and TechnologyMirpur 10250 AJKPakistan Neighbourhood of Akcaglan Imarli StreetNumber:28/4Eskisehir26030 Turkey

In this article,the(1/G')-expansion method,the Bernoulli sub-ordinary differential equation method and the modified Kudryashov method are implemented to construct a variety of novel analytical solutions to the(3+1)-dimensional Boiti-Leon-Manna-Pempinelli model representing the wave propagation through incompressible *** linearization of the wave structure in shallow water necessitates more critical wave capacity conditions than it does in deep water,and the strong nonlinear properties are *** novel travelling wave solutions have been observed including solitons,kink,periodic and rational solutions with the aid of the latest computing tools such as Mathematica or *** physical and analytical properties of several families of closed-form solutions or exact solutions and rational form function solutions to the(3+1)-dimensional Boiti-Leon-Manna-Pempinelli model problem are examined using Mathematica.

关键词： The(3+1)-dimensional Boiti-Leon-Manna-Pempinelli model The(1/G')-expansion method The Bernoulli sub-ODE method The modified Kudryashov method

Promotion of structural plasticity in area V2 of visual cortex prevents against object recognition memory deficits in aging and Alzheimer's disease rodents

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Neural Regeneration Research 2024年第8期19卷 1835-1841页

作者： Irene Navarro-Lobato Mariam Masmudi-Martín Manuel f.López-Aranda Juan f.López-Téllez Gloria Delgado Pablo Granados-Durán Celia Gaona-Romero Marta Carretero-Rey Sinforiano Posadas María E.Quiros-Ortega Zafar u.Khan Laboratory of Neurobiology Centro de Investigaciones Médico Sanitarias(CIMES)University of MalagaMalagaSpain Department of Medicine Faculty of MedicineUniversity of MalagaMalagaSpain Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas(CIBERNED) Institute of Health Carlos IIIMadridSpain the Donders Institute for Brain Cognition and Behaviour Radboud UniversityNijmegenThe Netherlands the Brain Metastasis Group National Cancer Research Centre(CNIO)MadridSpain the Department of Neurobiology University of California-Los AngelesLos AngelesCAUSA

Memory deficit,which is often associated with aging and many psychiatric,neurological,and neurodegenerative diseases,has been a challenging issue for *** till now,all potential drug candidates have failed to produce satisfa ctory ***,in the search for a solution,we found that a treatment with the gene corresponding to the RGS14414protein in visual area V2,a brain area connected with brain circuits of the ventral stream and the medial temporal lobe,which is crucial for object recognition memory(ORM),can induce enhancement of *** this study,we demonstrated that the same treatment with RGS14414in visual area V2,which is relatively unaffected in neurodegenerative diseases such as Alzheimer s disease,produced longlasting enhancement of ORM in young animals and prevent ORM deficits in rodent models of aging and Alzheimer’s ***,we found that the prevention of memory deficits was mediated through the upregulation of neuronal arbo rization and spine density,as well as an increase in brain-derived neurotrophic factor(BDNf).A knockdown of BDNf gene in RGS14414-treated aging rats and Alzheimer s disease model mice caused complete loss in the upregulation of neuronal structural plasticity and in the prevention of ORM *** findings suggest that BDNf-mediated neuronal structural plasticity in area V2 is crucial in the prevention of memory deficits in RGS14414-treated rodent models of aging and Alzheimer’s ***,our findings of RGS14414gene-mediated activation of neuronal circuits in visual area V2 have therapeutic relevance in the treatment of memory deficits.

关键词： behavioral performance brain-derived neurotrophic factor cognitive dysfunction episodic memory memory circuit activation memory deficits memory enhancement object recognition memory prevention of memory loss regulator of G protein signaling

miniSCIDOM: a scintillator-based tomograph for volumetric dose reconstruction of single laser-driven proton bunches

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High Power Laser Science and Engineering 2024年第2期12卷 41-50页

作者： A.Corvino M.Reimold E.Beyreuther f.-E.Brack f.Kroll J.Pawelke J.D.Schilz M.Schneider u.Schramm M.E.P.umlandt K.Zeil T.Ziegler J.Metzkes-Ng Helmholtz-Zentrum Dresden–Rossendorf DresdenGermany Technische universität Dresden DresdenGermany OncoRay–National Center for Radiation Research in Oncology Faculty of Medicine and University Hospital Carl Gustav CarusTUD Dresden University of TechnologyHelmholtz-Zentrum Dresden–RossendorfDresdenGermany Current affiliation:Institut Curie UniversitéPSLCNRS UMR3347OrsayFrance Current affiliation:universitätsklinikum freiburg FreiburgGermany

Laser plasma accelerators(LPAs)enable the generation of intense and short proton bunches on a micrometre scale,thus offering new experimental capabilities to research fields such as ultra-high dose rate radiobiology or material *** spectrally broadband,laser-accelerated proton bunches allow for tailored volumetric dose deposition in a sample via single bunches to excite or probe specific sample *** rising number of such experiments indicates a need for diagnostics providing spatially resolved characterization of dose distributions with volumes of approximately 1 cm^(3) for single proton bunches to allow for fast online *** we present the scintillator-based miniSCIDOM detector for online single-bunch tomographic reconstruction of dose distributions in volumes of up to approximately 1 cm^(3).The detector achieves a spatial resolution below 500μm and a sensitivity of 100 *** detector performance is tested at a proton therapy cyclotron and an LPA proton *** experiments’primary focus is the characterization of the scintillator’s ionization quenching behaviour.

关键词： beam monitoring detectors laser-driven proton beams scintillator-based diagnostics ultra-high dose rate

The impact of being in the COVID-19 pandemic on in-hospital mortality of non-infected patients aged 80 years and older with ST-elevation myocardial ınfarction

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Journal of Geriatric Cardiology 2024年第7期21卷 768-774页

作者： Mustafa Ebik Muhammet Gürdoğan uğurÖzkan Department of Cardiology Edirne Sultan 1.Murat State HospitalEdirneTurkey Department of Cardiology School of MedicineTrakya UniversityEdirneTurkey

The COVID-19 outbreak in late 2019 was declared a pandemic by the World Health Organization(WHO)on March 12,2020.[1]As of the latest WHO data,COVID-19 has caused over 770 million cases and nearly 7 million deaths worldwide.[2]Hospitalizations due to COVID-19 are correlated with advanced age.[3,4]According to re-ports,individuals over the age of 65 account for 80%of COVID-19-related deaths.[3,4]This is primar-ily due to the increased burden of comorbidity with age.

关键词： infected patients mortality

Development of immature ovarian teratoma after mature teratoma in a girl with familial ovarian teratoma:A case report

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World Journal of Clinical Cases 2024年第8期12卷 1442-1447页

作者： u Chul Ju Woo Dae Kang Seok Mo Kim Department of Obstetrics and Gynecology Chonnam National University Medical SchoolGwangju 61469South Korea

BACKGROuND Immature ovarian teratoma is a rare and aggressive neoplasm that affects young *** report is the first to describe the development of immature teratoma after ovarian cystectomy for mature teratoma of the ovary in an adolescent female with a family history of ovarian *** SuMMARY A 16-year-old girl who had undergone bilateral ovarian cystectomy for mature teratomas 3 years ago showed bilateral adnexal tumors during her regular ultrasonography follow-up every 6 *** received laparoscopic bilateral ovarian cystectomy,and final histopathology showed grade-1 immature teratoma of the left ovary and mature teratoma of the right *** left salpingo-oophorectomy and staging procedures were performed *** mother,maternal aunt,and maternal grandmother had also received surgeries for mature ovarian *** It is important to have guidance on management of patient and family members with familial ovarian teratomas.

关键词： familial ovarian teratomas Adolescent female Immature ovarian teratoma Management Case report

Bolstering integrity in environmental data science and machine learning requires understanding socioecological inequity

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frontiers of Environmental Science & Engineering 2024年第5期18卷 171-179页

作者： Joe f.Bozeman III School of Civil and Environmental Engineering Georgia Institute of TechnologyAtlantaGA30332USA School of Public Policy Georgia Institute of TechnologyAtlantaGA30332USA

Socioecological inequity in environmental data science—such as inequities deriving from data-driven approaches and machine learning(ML)—are current issues subject to debate and *** is growing consensus around embedding equity throughout all research and design domains—from inception to administration,while also addressing procedural,distributive,and recognitional ***,practically doing so may seem onerous or daunting to *** current perspective helps to alleviate these types of concerns by providing substantiation for the connection between environmental data science and socioecological inequity,using the Systemic Equity framework,and provides the foundation for a paradigmatic shift toward normalizing the use of equity-centered approaches in environmental data science and ML *** the integrity of environmental data science and ML is just beginning from an equity-centered tool development and rigorous application *** this end,this perspective also provides relevant future directions and challenges by overviewing some meaningful tools and strategies—such as applying the Wells-Du Bois Protocol,employing fairness metrics,and systematically addressing irreproducibility;emerging needs and proposals—such as addressing data-proxy bias and supporting convergence research;and establishes a ten-step path ***,the work that environmental scientists and engineers do ultimately affect the well-being of us all.

关键词： Equity Bias Machine Learning Data Science Justice Systemic Equity