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Underground Space 2024年第2期15卷 44-58页

作者： Yadong Zhang ron Chik-Kwong Wong Jianf.ng Chen Wei Su Department of.Civil Engineering Schulich School of EngineeringUniversity of CalgaryCalgaryAB T2N 1N4Canada Department of.Geotechnical Engineering College of Civil EngineeringTongji UniversityShanghai 200092China

During pipe installation,compacting soil at pipe sides causes an initial pipe def.rmation which is known as the"peaking"***,in conventional pipe design codes,only pipe def.rmation caused by vertical overburden is considered while the"peaking"ef.ect is *** this study,a f.ll-scale test was conducted on a Grade X52 steel pipe with a diameter of.600 mm to investigate the impacts of.both soil compaction and vertical overburden on pipe *** compaction and external load were f.und to elongate and shorten the vertical pipe diameter,***"peaking"ef.ect was observed during the installation procedure accompanied by the highest pipe stress measured at the pipe ***,a two-dimensional f.nite element model was created and validated based on the calculated pipe stresses f.om the experimental study.A parametric study was perf.rmed thereaf.er to numerically study the impacts of.soil water content,pipe wall thickness,compaction pressure,and lif. thickness on pipe responses due to soil compaction and external *** increase in the"peaking"ef.ect is observed with increasing soil water content and compaction pressure,while an increase in pipe wall thickness or lif. thickness would cause a decrease in the"peaking"ef.ect.

关键词： X52 steel Soil compaction External load Peaking ef.ect Pipe def.ection Soil arching

专访传奇国际设计大师ron Arad:创造前所未有的设计

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包装与设计 2024年第2期 4-33页

作者： ron Arad 不详

他是国际设计界的传奇人物,毕业于著名的英国伦敦建筑联盟学院(Architectural Association,简称AA),集产品设计师、家具设计师、建筑设计师、艺术家多重身份于一身.他创作的工作室限量版艺术作品一次又一次地成功转为市场畅销产品,而他... 详细信息

他是国际设计界的传奇人物,毕业于著名的英国伦敦建筑联盟学院(Architectural Association,简称AA),集产品设计师、家具设计师、建筑设计师、艺术家多重身份于一身.他创作的工作室限量版艺术作品一次又一次地成功转为市场畅销产品,而他设计的工业产品又如艺术品,令人大开眼界,吸引了全球各大知名博物馆争相展示和收藏.

关键词：工业产品建筑设计师设计大师限量版家具设计师畅销产品产品设计师多重身份

美国ST Paper的差异化经营:灵活生产,推动绿色能源使用

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生活用纸 2024年第5期24卷 58-59页

作者： ron Thiry ST Paper

随着美国家族企业独立生活用纸生产商ST Paper最新投资项目——PrimeLineTM W 2000于2023年1月在位于美国明尼苏达州Duluth的工厂启动,公司已为进一步扩张做好了准备。Tissue World杂志采访了ST Paper公司的高级副总裁兼首席运营官ron T... 详细信息

随着美国家族企业独立生活用纸生产商ST Paper最新投资项目——PrimeLineTM W 2000于2023年1月在位于美国明尼苏达州Duluth的工厂启动,公司已为进一步扩张做好了准备。Tissue World杂志采访了ST Paper公司的高级副总裁兼首席运营官ron Thiry。

关键词：家族企业差异化经营生活用纸绿色能源首席运营官 ST

Basic science of.water： Challenges and current status towards a molecular picture

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Nano Research 2015年第10期8卷 3085-3085,3086-3110页

作者： Sheng Meng Lauren f. Greenlee Yuen ron Shen Enge Wang BeijingNationalLabf.rCondensedMatterPhysics InstituteofPhysicsChineseAcademyofSciencesBeijing100190China AppliedChemicalsandMaterialsDivision NationalInstituteofStandardsandTechnology325BroadwayMS647BoulderCO80305USA Departmentof.hysics UniversityofCaliforniaBerkeleyCA94720USA InternationalCenterf.rQuantumMaterials SchoolofPhysicsPekingUniversityBeijing100871China

Rapid developments in both f.ndamental science and modern technology that target water-related problems, including the physical nature of.our planet and environment, the origin of.lif., energy production via water splitting, and water purif.cation, all call f.r a molecular-level understanding of.water. This invokes relentless ef.orts to f.rther our understanding of.the basic science of.water. Current challenges to achieve a molecular picture of.the peculiar properties and behavior of.water are discussed herein, with a particular f.cus on the structure and dynamics of.bulk and surf.ce water, the molecular mechanisms of.water wetting and splitting, application-oriented research on water decontamination and desalination, and the development of.complementary techniques f.r probing water at the nanoscale.

关键词： water molecular structure surf.ce water water treatment nanotechnology water properties

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评价标记“你说”和“别说”的用法比较

汉语学习 2024年第2期 10-21页

作者：周莉董涵容吉林大学文学院吉林长春130012 上海师范大学对外汉语学院上海200234

本文主要探讨评价标记“你说”和“别说”的功能差异及成因。研究发现,二者差异主要体现在评价话语的信息结构、后续话语形式和语音停顿等方面,这些差异取决于二者语义功能的不同:一是评价对象不同;二是互动性不同。二者源结构在会话不... 详细信息

本文主要探讨评价标记“你说”和“别说”的功能差异及成因。研究发现,二者差异主要体现在评价话语的信息结构、后续话语形式和语音停顿等方面,这些差异取决于二者语义功能的不同:一是评价对象不同;二是互动性不同。二者源结构在会话不同序列位置的不同用法,即“别说”处于引发序列的语用推理和“你说”处于回应序列的引述回应决定了二者功能的差异。本文最后总结出言者引发评论时使用评价标记“你说/别说”的条件。

关键词：评价标记 “你说” “别说” 互动差异

Wastewater Surveillance Provides Spatiotemporal SARS-CoV-2 Inf.ction Dynamics

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Engineering 2024年第9期40卷 70-77页

作者： Xiawan Zheng Kathy Leung Xiaoqing Xu Yu Deng Yulin Zhang Xi Chen Chung In Yau Kenny W.K.Hui Eddie Pak Ho-Kwong Chui ron Yang Hein Min Tun Gabriel Matthew Leung Joseph Tsz Kei Wu Malik Peiris Leo Lit Man Poon Tong Zhang Environmental Microbiome Engineering and Biotechnology Lab Center for Environmental Engineering ResearchDepartment of Civil EngineeringThe University of Hong KongHong Kong 999077China WHO Collaborating Centre f.r Inf.ctious Disease Epidemiology and Control School of Public HealthLi Ka Shing Faculty of MedicineThe University of Hong KongHong Kong 999077China Laboratory of.Data Discovery f.r Health Litd.(D24H) Hong Kong 999077China The University of.Hong Kong-Shenzhen Hospital Hong Kong 999077China School of.Public Health Li Ka Shing Faculty of MedicineThe University of Hong KongHong Kong 999077China HKU-Pasteur Research Pole The University of Hong KongHong Kong 999077China Drainage Services Department The Government of the Hong Kong Special Administrative RegionHong Kong 999077China Environmental Protection Department The Government of the Hong Kong Special Administrative RegionHong Kong 999077China The Jockey Club School of.Public Health and Primary Care Faculty of MedicineThe University of Hong KongHong Kong 999077China

Wastewater surveillance(WWS)can leverage its wide coverage,population-based sampling,and high monitoring f.equency to capture citywide pandemic trends independent of.clinical *** we conducted a nine months daily WWS f.r severe acute respiratory syndrome coronavirus 2(SARSCoV-2)f.om 12 wastewater treatment plants(WWTPs),covering approximately 80%of.the population,to monitor inf.ction dynamics in Hong Kong,*** f.und that the SARS-CoV-2 virus concentration in wastewater was correlated with the daily number of.reported cases and reached two pandemic peaks three days earlier during the study *** addition,two dif.erent methods were established to estimate the prevalence/incidence rates f.om wastewater *** estimated results f.om wastewater were consistent with f.ndings f.om two independent citywide clinical surveillance programmes(rapid antigen test(RAT)surveillance and serology surveillance),but higher than the cases number reported by the Centre f.r Health Protection(CHP)of.Hong Kong,***,the ef.ective reproductive number(R_(t))was estimated f.om wastewater measurements to ref.ect both citywide and regional transmission *** f.ndings demonstrate that large-scale intensive WWS f.om WWTPs provides cost-ef.ective and timely public health inf.rmation,especially when the clinical surveillance is inadequate and *** approach also provides insights into pandemic dynamics at higher spatiotemporal resolutions,f.cilitating the f.rmulation of.ef.ective control policies and targeted resource allocation.

关键词： SARS-CoV-2 Wastewater surveillance Prevalence Ef.ective reproductive number

A chromosome-scale genome assembly of.Rauvolf.a tetraphylla f.cilitates identif.cation of.the complete ajmaline biosynthetic pathway

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Plant Communications 2024年第4期5卷 129-132页

作者： Enzo Lezin Ines Carqueijeiro Clement Cuello Mickael Durand Hans JJansen Valentin Verges Caroline Birer Williams Audrey Oudin Thomas Duge de Bernonville Julien Petrignet Noemie Celton Benoit St-Pierre Nicolas Papon Chao Sun ron P.Dirks Sarah Ellen O’Connor Michael Krogh Jensen Sebastien Besseau Vincent Courdavault Biomole´cules et Biotechnologies Vegetales EA2106Universite´de Tours37200 ToursFrance f.ture Genomics Technologies 2333 BE Leidenthe Netherlands Laboratoire Synthe se et Isolement de Molecules BioActives(SIMBA EA 7502)Universitede Tours37200 ToursFrance Laboratoire de Cytoge´netique Constitutionnelle CHRU de Tours-Hopital Bretonneau37044 ToursFrance University Angers University BrestIRFSFR ICAT49000 AngersFrance Institute of.Medicinal Plant Development Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 2800China Department of.Natural Product Biosynthesis Max Planck Institute for Chemical Ecology07745 JenaGermany Novo Nordisk f.undation Center f.r Biosustainability Technical University of Denmark100193 Kgs LyngbyDenmark Present address:Limagrain Center de RechercheRoute d’EnnezatChappesFrance These authors contributed equally to this article

Dear Editor,Rauvolf.a tetraphylla(aka the Devil pepper)(Supplemental f.gure 1)is a well-known medicinal plant that produces monoterpenoid indole alkaloids(MIAs).This MIA biosynthesis occurs in several organs,including leaves,stems,f.uit,and roots,which accumulate the f.mous antiarrhythmic ajmaline(Kumar et al.2016a,2016b;Kumara et al.,2019).MIAs are natural products notably involved in plant adaptation to the environment and def.nse against *** mainly results f.om their high biological activities,which also explain their pharmacological properties.

关键词： properties. f.gure roots

Pathogenesis and clinical f.atures of.severe hepatitis E virus inf.ction

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World Journal of.Virology 2024年第2期13卷 19-33页

作者： László Orosz Károly Péter Sárvári Áron Dernovics András Rosztóczy Klára Megyeri Department of.Medical Microbiology University of SzegedSzeged 6720Csongrád-CsanádHungary Department of.Internal Medicine Division of GastroenterologyUniversity of SzegedSzeged 6725Csongrád-CsanádHungary

The hepatitis E virus(HEV),a member of.the Hepeviridae f.mily,is a small,non-enveloped icosahedral virus divided into eight distinct genotypes(HEV-1 to HEV-8).Only genotypes 1 to 4 are known to cause diseases in *** 1 and 2 commonly spread via f.cal-oral transmission,of.en through the consum-ption of.contaminated *** 3 and 4 are known to inf.ct pigs,deer,and wild boars,of.en transf.rring to humans through inadequately cooked *** hepatitis caused by HEV in healthy individuals is mostly asymptomatic or associated with minor symptoms,such as ***,in immunosup-pressed individuals,the disease can progress to chronic hepatitis and even escalate to *** pregnant women,an HEV inf.ction can cause f.lminant liver f.ilure,with a potential mortality rate of.25%.Mortality rates also rise amongst cirrhotic patients when they contract an acute HEV inf.ction,which can even trigger acute-on-chronic liver f.ilure if.layered onto pre-existing chronic liver *** the prevalence of.HEV inf.ction continues to rise worldwide,highlighting the particular risks associated with severe HEV inf.ction is of.major medical *** text of.ers a brief.summary of.the characteristics of.hepatitis developed by patient groups at an elevated risk of.severe HEV inf.ction.

关键词： Hepatitis E virus Cirrhosis Acute-on-chronic liver f.ilure Pregnancy Immune dysf.nction Open reading f.ames 1-4

Relevance of.plasma lipoproteins and small metabolites in assessment of.nutritional status among patients with severe injuries

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Journal of.Intensive Medicine 2024年第4期4卷 496-507页

作者： Esmee A.H.Verheul Suzan Dijkink Pieta Krijnen Aswin Verhoeven Martin Giera Roula Tsonaka Jochem M.Hoogendoorn Sesmu M.Arbous ron Peters Inger B.Schipper Department of.Trauma Surgery Leiden University Medical CenterLeidenThe Netherlands Acute Care Network West Netherlands LeidenThe Netherlands Center f.r Proteomics and Metabolomics Leiden University Medical CenterLeidenThe Netherlands Department of.Biomedical Data Sciences Leiden University Medical CenterLeidenThe Netherlands Department of.General Surgery Haaglanden Medical CenterThe HagueThe Netherlands Department of.Intensive Care Leiden University Medical CenterLeidenThe Netherlands Department of.Intensive Care Haaglanden Medical CenterThe HagueThe Netherlands

Background:This study aimed to identif. plasma lipoproteins and small metabolites associated with high risk of.malnutrition during intensive care unit(ICU)stay in patients with severe ***:This observational prospective exploratory study was conducted at two level-1 trauma centers in the *** patients(aged≥18 years)who were admitted to the ICU f.r more than 48 h between July 2018 and April 2022 owing to severe injuries(polytrauma,as def.ned by Injury Severity Scores of.16)caused by blunt trauma were eligible f.r *** least squares discriminant analysis was used to analyze the relationship of.112 lipoprotein-related components and 23 small metabolites with the risk of.malnutrition(mod-if.ed Nutrition Risk in Critically Ill score).Malnutrition was diagnosed based on Subjective Global Assessment *** relationship of.lipoprotein properties and small metabolite concentrations with malnutrition(during ICU admission)was evaluated using mixed ef.ects logistic ***:Overall,51 patients were ***(very)low-density lipoprotein([V]LDL)(f.ee)cholesterol and phospholipid levels,low particle number,and higher levels of.LDL triglycerides were associated with a higher risk of.malnutrition(variable importance in projection[VIP]value>1.5).Low levels of.most(V)LDL and intermediate-density lipoprotein subf.actions and high levels of.high-density lipoprotein Apo-A1 were associated with the diagnosis of.malnutrition(VIP value>1.5).Increased levels of.dimethyl sulf.ne,trimethylamine N-oxide,creatinine,N,N-dimethylglycine,and pyruvic acid and decreased levels of.creatine,methionine,and acetoacetic acid were also indicative of.malnutrition(VIP value>1.5).Overall,14 lipoproteins and 1 small metabolite were signif.cantly associated with a high risk of.malnutrition during ICU admission(Pf.er correcting the f.lse discovery rate(P=0.35 f.r all).Conclusion:Increased triglyceride in sev

关键词： Trauma Severely injured Metabolites Lipoproteins Malnutrition Nutritional status

Social Data:CESSDA Best Practices

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Data Intelligence 2020年第1期2卷 220-229,316页

作者： ron Dekker Main Of.ice of.the Consortium of.Social Science Data Archives Parkveien 20BergenNorway

The European Commission report“Turning f.IR into reality”provides an index of.27 f.IR Action Plan *** index is used f.r a self.assessment on CESSDA,the Consortium of.European Social Science Data *** is perf.rming well on“Concepts f.r f.IR implementation”,“Skills f.r f.IR”,and“Investment in f.IR”;there is work in progress on“f.IR culture”,and work to start up on“f.IR ecosystem”and especially on“Incentives and metrics f.r f.IR data and services”.Next,an analysis on the f.IR components,reveals that CESSDA has accomplished the“f.,is working on the“A”-considering the sensitivity and security requirements of.social data,just started on“I”,and that there is lack of.clarity on what should be in“R”.On f.ndability,the CESSDA Data Catalogue is explained,showing the building blocks that need to be in place bef.re one can produce a *** article ends with a f.rward look on CESSDA’s deployment on the f.IR principles.

关键词： Social data Distributed inf.astructure f.IR Action Plan Data catalogue