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Open j.urnal of Geology 2018年第8期8卷 819-840页

作者： ezekiel j. seni Gabriel D. Mulibo Giovanni Bertotti Department of Geology University of Dar es Salaam Dar es Salaam Tanzania Department of Geoscience and Civil engineering Deft University of Technology Delft The Netherland

Sedimentary deposits in Block 5, offshore Tanzania basin have been imaged using two-dimensional (2D) seismic data. The seismic data and well data reveal four tectonic units representing different tectonic events in relation to structural styles, sedimentation and hydrocarbon potential evolved in Block 5. Results show that during Early to Late j.rassic, Block 5 was affected by the break-up of Gondwana and the drifting of Madagascar as evidenced by patterns of sediments and structural features. The chaotic and discontinuous reflectors are characteristics features on the sediments pattern indicating a possible transitional setting following the breakup of Gondwana. From the Late Cretaceous, Block 5 sits in more stable subsiding sag as the consequence of the high thermal subsidence. The period displayed continuous parallel reflectors with few markable faults. This was followed by the late post rift sedimentation that occurred after Middle Eocene Unconformity characterized by high wavy and sub parallel reflectors. The evolution of Block 5 through maj.r tectonic events reveals a more complete petroleum system towards the south. Thus, Block 5 responded in both space and time to a complex interplay between tectonics and sedimentation. This indicates that structural styles and associated features are potential control for hydrocarbon generation and migration.

关键词： Offshore Tanzania basin Block 5 Tectonics Sedimentation Hydrocarbon East Africa

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Magnetic resonance imaging biomarkers for pulsed focused ultrasound treatment of pancreatic ductal adenocarcinoma

生物医学研究和国际合作研究中的伦理问题研讨会

作者： ezekiel j.Emanuel Reidar K.Lie MD PhD Chief Department of Clinical Bioethics National Institutes of Health MD PhD HeadSection on International Research Department of Clinical Bioethics National Institutes of Health

＜正＞j.ne 8,2007 During the past years there has been significant-controversy over the ethics of research with human *** the ethical issues vehemently debated are the use of placebos,the guarantee of interventions af...

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World j.urnal of Gastroenterology 2020年第9期26卷 904-917页

作者： ezekiel Maloney Yak-Nam Wang Ravneet Vohra Helena Son Stella Whang Tatiana Khokhlova j.shua Park Kayla Gravelle Stephanie Totten j.o Ha Hwang Donghoon Lee Department of Radiology University of WashingtonSeattleWA 98195United States Applied Physics Laboratory University of WashingtonSeattleWA 98195United States Division of Gastroenterology University of WashingtonSeattle 98195WAUnited States Division of Gastroenterology&Hepatology Stanford University School of MedicineRedwood CityCA 94063United States

BACKGROUND The robust fibroinflammatory stroma characteristic of pancreatic ductal adenocarcinoma(PDA)impedes effective drug *** focused ultrasound(pFUS)can disrupt this stroma and has improved survival in an early clinical ***-invasive methods to characterize pFUS treatment effects are desirable for advancement of this promising treatment modality in larger clinical *** To identify promising,non-invasive pre-clinical imaging methods to characterize acute pFUS treatment effects for in vivo models of *** We utilized quantitative magnetic resonance imaging methods at 14 tesla in three mouse models of PDA(subcutaneous,orthotopic and transgenic-KrasLSLG12D/+,Trp53LSL-R172H/+,Cre or“KPC”)to assess immediate tumor response to pFUS treatment(VIFU 2000 Alpinion Medical Systems;475 W peak electric power,1 ms pulse duration,1 Hz,duty cycle 0.1%)vs sham therapy,and correlated our results with histochemical *** pFUS treatment parameters were previously shown to enhance tumor permeability to chemotherapeutics.T1 and T2 relaxation maps,high(126,180,234,340,549)vs low(7,47,81)b-value apparent diffusion coefficient(ADC)maps,magnetization transfer ratio(MTR)maps,and chemical exchange saturation transfer(CEST)maps for the amide proton spectrum(3.5 parts per million or“ppm”)and the glycosaminoglycan spectrum(0.5-1.5 ppm)were generated and analyzed pre-treatment,and immediately post-treatment,using *** were sacrificed immediately following post-treatment *** whole-tumor was selected as the region of interest for data analysis and subsequent statistical analysis.T-tests and Pearson correlation were used for statistical *** Mean high-b value ADC measurements increased significantly with pFUS treatment for all *** glycosaminoglycan CEST and T2 measurements decreased significantly post-treatment for the KPC *** MTR and amide CEST values increased significantly for the KPC *** acid focal int

关键词： Pancreatic adenocarcinoma Multiparametric magnetic resonance imaging Focused ultrasound

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The Use of Bovine Collagen and Skin Graft for Reconstruction of the Glans Penis Following Cancer Resection

作者： (美)伊齐基尔·伊曼纽尔(ezekiel j. Emanuel)

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Open j.urnal of Urology 2012年第3期2卷 216-218页

作者： Zhongyi Sun Varsha R. Sinha ezekiel E. Young Brian Bensadigh Carmen Ceron Bruce R. Kava j.nnifer N. Landon Christopher j. Salgado Division of Plastic Surgery DeWitt Daughtry Department of Surgery Leonard M. Miller School of Medicine University of Miami Miami USA

Penile reconstruction following cancer resection has long been a challenge due to demand for both aesthetic and functional preservation. Although various methods have attempted to achieve both goals, none have succeeded entirely. In this report, we introduce a novel reconstructive technique on a 64-year-old patient with squamous cell carcinoma of the glans penis. The technique consisted of two staged procedures. First, a dermal substitute, consisting of bovine collagen, was sutured onto the defect after partial glansectomy and three weeks later, the integrated dermis was covered with autologous non-meshed partial thickness skin graft. Use of this dermal substitute in a staged fashion allowed for ability to await final pathologic margins prior to definitive reconstruction and increased dermal thickness. After 9-month follow-up, sexual function returned within 3 months and the patient remained healed. We found this technique to be useful in concurrently preserving penile function and cosmesis. Future studies should include more patients and longer follow-up.

关键词： Glans Penis Bovine Collagen Integra Penis

Soil Carbon Dioxide Efflux and Atmospheric Impact in a 10-Year-Old Dipterocarpus Recovering Lowland Tropical Forest, Peninsular Malaysia

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j.urnal of Earth Science and Engineering 2017年第1期7卷 37-50页

作者： Mande Kato Hosea Ahmad Makmom Abdullah Ahamad Zaharin Aris Ahmad Ainuddin Nuruddin Nghai ezekiel Suleman Kasham j. Shamang Baj. j.lius Babarinsa Deborah Sabo Douglas Gugong K. Benj.min Bala Dogo Sim Haruna Gabriel Emmanuel Elimisiemon M. Christopher Air Pollution & Ecophysiology Laboratory Department of Environmental Planning & Management Faculty of Environmental Studies Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia Department of Environmental Sciences Faculty of Environmental Studies Universiti Putra Malaysia 43400 UPM Serdang Selangor Darul Ehsan Malaysia Environmental Forensics Research Centre Faculty of Environmental Studies Universiti Putra Malaysia 43400 UPM Serdang Selangor Darul Ehsan Malaysia Institute of Tropical Forest and Forest Product Universi(y Putra Malaysia 43400 UPM Serdang Selangor Darul Ehsan Malaysia Department of Architecture Faculty of Environmental Science Kaduna State University PM.B 2339 Kaduna Nigeria Department of Environmental Management Faculty of Environmental Science Kaduna State University P.M.B 2339 KadunaNigeria Department of Accounting Faculty of Art Kaduna State University P.M.B 2339 Kaduna Nigeria Department of Geography Faculty of Sciences Kaduna State University P M. B 2339 Kaduna Nigeria Department of Basic and Remedial Studies School of Agricultural Technology Nuhu Bamalli Polytechnic Zaria Samaru Kataf Campus Kaduna State Nigeria Department of Urban and Regional Planning P.M.B 704 FUT Akure Ondo State Nigeria

The recovering logged-over forest ecosystem increases the CO2 efflux into the atmospheric carbon pool in response to environmental factors to changes in the soil temperature and moisture. These CO2 outbursts can have a marked influence on the ecosystem carbon balance and thereby affect the atmospheric carbon pool. The study was conducted in the 10-year-old logged-over forest of Sungai Menyala forest, Port Dickson, Negeri Sembilan, Malaysia. The measurements of soil CO2 efflux were conducted using the continuous open flow chamber technique connected to a multi gas-handling unit and infrared CO2/H2O gas analyser. The aim of this study was to determine the soil CO2 efflux and the environmental variables and likewise the impact of environmental factors on soil CO2 efflux. Post-hoc comparisons were made using the Tukey test （p 〈 0.05）, and multiple linear regression to determine the impact of environmental factors on soil CO2 efflux. Soil CO2 efflux ranged from 100.22-553.40 mg m^-2 h^-1 with the highest efflux in the afternoon attributed to an increase in soil temperature and low moisture. A higher soil temperature and low moisture signify an influential factor as the forest is recovering from logging activity. Furthermore, the predictor environmental variables： SOC （soil organic carbon）, TOC （total organic carbon）, SMC （soil moisture content）, Bulk Density, SOCstock （soil organic carbon stock）, TAGB （total above ground carbon biomass）, Below Ground Carbon Biomass, soil pH, Nitrogen to Carbon ratio account for the spatial and temporal variation in soil CO： efflux into the atmosphere. The analysis revealed a strong correlation between soil CO2 efflux, changes soil properties and environmental factors with an R^2 more than 0.80 at p 〈 0.01. This is proven that logging activity accounts for the changes in environmental factors to influence soil CO2 efflux rate within 10-years of logging and forest recovering.

关键词： Biomass forest ecosystem carbon pool carbon sink and soil CO2 efflux.