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The Use of Bovine Collagen and Skin Graft for Reconstruction of the Glans Penis Following Cancer Resection

The Use of Bovine Collagen and Skin Graft for Reconstruction of the Glans Penis Following Cancer Resection

作     者:Zhongyi Sun Varsha R. Sinha Ezekiel E. Young Brian Bensadigh Carmen Ceron Bruce R. Kava Jennifer N. Landon Christopher J. Salgado 

作者机构:Division of Plastic Surgery DeWitt Daughtry Department of Surgery Leonard M. Miller School of Medicine University of Miami Miami USA 

出 版 物:《Open Journal of Urology》 (泌尿学期刊(英文))

年 卷 期:2012年第2卷第3期

页      面:216-218页

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主  题:Glans Penis Bovine Collagen Integra Penis 

摘      要:Penile reconstruction following cancer resection has long been a challenge due to demand for both aesthetic and functional preservation. Although various methods have attempted to achieve both goals, none have succeeded entirely. In this report, we introduce a novel reconstructive technique on a 64-year-old patient with squamous cell carcinoma of the glans penis. The technique consisted of two staged procedures. First, a dermal substitute, consisting of bovine collagen, was sutured onto the defect after partial glansectomy and three weeks later, the integrated dermis was covered with autologous non-meshed partial thickness skin graft. Use of this dermal substitute in a staged fashion allowed for ability to await final pathologic margins prior to definitive reconstruction and increased dermal thickness. After 9-month follow-up, sexual function returned within 3 months and the patient remained healed. We found this technique to be useful in concurrently preserving penile function and cosmesis. Future studies should include more patients and longer follow-up.

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