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当代建筑 2024年第7期 110-117页

作者：无 Brett Boardman(摄影) Justin Alexander(摄影) evan zell(摄影) 杰克逊蒂斯建筑设计事务所不详

蒙蒂菲奥里的M养老住宅是悉尼市中心一个高品质养老社区中的独立住宅部分,是对原有养老社区的扩建和更新。这两栋新独立住宅楼位于兰德威克国王街,这里曾经是悉尼电车中心的所在地。

关键词：就地养老适应性社会责任

Operando NMR methods for studying electrocatalysis

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Magnetic Resonance Letters 2024年第2期4卷 54-64页

作者： Zhiyu Zhu Ruipeng Luo evan Wenbo Zhao Magnetic Resonance Research Center Institute for Molecules and MaterialsRadboud University6525 AJ Nijmegenthe Netherlands

The combination of electrochemical measurements with spectroscopic characterizations provides valuable insights into reaction *** magnetic resonance(NMR)spectroscopy,as a powerful technique due to its atomic specificity and versatility in studying gas,liquid,and solid,allows the study of electrolyte solution,catalyst and catalyst-adsorbate *** applied in operando,NMR can offer molecular-level insights into various electrochemical *** NMR has been applied extensively in battery research,but relatively underexplored for electrocatalysis in the past two *** this mini review,we first introduce the operando electrochemical NMR setups,categorized by different probe *** we review the applications of operando NMR for monitoring the electrolyte solution and the catalyst-adsorbate *** the high environmental impact of electrochemical conversion of CO_(2)into value-added products,we zoom in to the use of operando NMR in studying electrochemical CO_(2)***,we provide our perspective on further developing and applying operando NMR methods for understanding the complex reaction network of Cu-catalyzed electrochemical CO_(2)reduction.

关键词： Operando NMR In situ NMR EC-NMR Electrocatalysis Electrochemical CO_(2)reduction

A Study on Multivariable Interactions Concerning Radar Cross Section Reduction through Geometric Attributes

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Journal of Applied Mathematics and Physics 2024年第7期12卷 2582-2593页

作者： evan Sharp STEAM Institute Jacksonville University Jacksonville FL USA

This resolution 5 (25−1 factorial) study aimed to ascertain an understanding of the interactions between different geometries on the resulting Radar Cross Section (RCS) of a target. The results of the study are in line with the general understanding of the impact different geometries have on RCS but show that geometries can also influence the variance of measured RCS, and typical attributes that reduce RCS increase the variance of the measured RCS. Notably, an increased angle between the front face of a plate and the direction of the radar signal decreased RCS but increased the variance of the RCS measured.

关键词： Radar Cross Section RCS Geometrical Attributes Radar Stealth

An Expanded View of Complex Traits:From Polygenic to Omnigenic

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四川生理科学杂志 2024年第1期46卷 139-139页

作者： evan A Boyle Department of Genetics Stanford University Stanford CA 94305 USA. Electronic address: eaboyle@stanford.edu. Department of Genetics Stanford University Stanford CA 94305 USA. Electronic address: yangili@stanford.edu. Department of Genetics Stanford University Stanford CA 94305 USA Department of Biology Stanford University Stanford CA 94305 USA Howard Hughes Medical Institute Stanford University Stanford CA 94305 USA. Electronic address: pritch@stanford.edu.

A central goal of genetics is to understand the links between genetic variation and ***,one might expect diseasecausing variants to cluster into key pathways that drive disease *** for complex traits,association signa... 详细信息

关键词： Traits cluster Complex

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第2期10卷 97-104页

作者： Mihai A.Bentan evan R.Reiter Richard M.Costanzo Daniel H.Coelho Department of Otolaryngology-Head&Neck Surgery Virginia Commonwealth University School of MedicineRichmondVirginiaUSA

Objective:The aim of this study was to review findings from a large prospective national database of chemosensory disturbances associated with coronavirus disease 2019(COVID-19)*** Sources:The Virginia Commonwealth University Smell and Taste Center national database of COVID-19 chemosensory ***:A series of online surveys,first opened on April 10,2020,was made accessible nationwide to any adult with sudden chemosensory dysfunction since January *** received subsequent follow-up surveys 14 days,1 month,3 months,and 6 months after *** additional survey was sent to all participants on May 28,2022 to assess long-term *** pertaining to demographics,symptoms,comorbidities,treatments,and life impact was ***:Of 363 participants who reported complete smell recovery,51.2%recovered within 1 month,70%within 3 months,and 79%within 6 months,while 8.8%took over 1 year to completely *** all participants,7.5%had no smell *** predictors of recovery included age<40,male gender,and the presence of nasal *** predictors included difficulty breathing and prior head *** participants reported a decrease in quality of life and the presence of potential safety hazards associated with decreased smell ***:Most subjects with COVID-19-related chemosensory dysfunction recover,with the majority noting complete recovery within weeks of *** aged over 40 years and female gender were associated with lower rates of recovery.A considerable number of participants reported significant impact on quality of life and safety.

关键词： anosmia COVID-19 smell

Investigation of HCAR2 antagonists as a potential strategy to modulate bovine leukocytes

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Journal of Animal Science and Biotechnology 2024年第4期15卷 1567-1577页

作者： Laman K.Mamedova Kirby C.Krogstad Paiton O.McDonald Laxman Pokhrel Duy H.Hua evan C.Titgemeyer Barry J.Bradford Department of Animal Science Michigan State UniversityEast LansingMichigan 48824USA Department of Animal Sciences and Industry Kansas State UniversityManhattanKS 66506USA Comparative Medicine and Integrative Biology East LansingMI 48824USA Department of Chemistry Kansas State UniversityManhattanKS 66506USA

Background Dairy cows experiencing ketosis after calving suffer greater disease incidence and are at greater risk of leaving the herd. In vitro administration of beta-hydroxybutyric acid(BHBA;the primary blood ketone) has inhibitory effects on the function of bovine leukocytes. BHBA is a ligand of HCAR2 and the activation of these receptors promotes an anti-inflammatory response which may be related with immunosuppression observed in transition dairy cattle. The objective of this study was to identify and test antagonists for HCAR2 in bovine immune cells cultured with *** We observed expression of HCAR2 at the protein level within lymphocytes, monocytes, and granulocytes. The proportion of cells expressing HCAR2 tended to be greater in mid-lactation compared to early lactation cows;the increase was a result of increased proportion of T and B cells expressing HCAR2. Stimulation of HCAR2 with niacin or BHBA promoted Ca^(2+) mobilization in neutrophils and mononuclear cells. Mononuclear cells treated with BHBA had diminished intracellular Ca^(2+) responses when HCAR2 was knocked down by si RNA silencing, indicating Ca^(2+) mobilization was mediated by HCAR2 signaling. Two candidate antagonists for HCAR2, synthesized from niacin(NA-1 and NA-5), were tested;monocytes and neutrophils pre-treated with NA-1 and NA-5 had reduced Ca^(2+) mobilization after incubation with BHBA. Furthermore, NA-5 but not NA-1 prevented BHBA-associated reductions in cyclic *** We demonstrated that HCAR2 is present on bovine leukocytes and has greater expression later in lactation. We confirmed that BHBA and niacin derived HCAR2 antagonists alter bovine leukocyte activity. Our results demonstrate that both BHBA and niacin affect bovine leukocyte Ca^(2+) mobilization in a HCAR2-dependent manner.

关键词： Flow cytometry GPR109A HM74A Ketosis

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Atlas摒弃液压系统

科技纵览 2024年第6期 8-9页

作者： evan Ackerman 不详

波士顿动力公司的人形机器人实现电动化并超越了人类的能力。过去10年间,波士顿动力公司的Atlas可以说是现有能力最强、最显眼的人形机器人。但近年来,至少有8家资金雄厚的公司怀有商业野心,开发了自己的人形机器人。即使波士顿动力公... 详细信息

波士顿动力公司的人形机器人实现电动化并超越了人类的能力。过去10年间,波士顿动力公司的Atlas可以说是现有能力最强、最显眼的人形机器人。但近年来,至少有8家资金雄厚的公司怀有商业野心,开发了自己的人形机器人。即使波士顿动力公司开始销售包括电动Spot四足机器人和Stretch搬运机器人在内的其他几种系统,Atlas也仍旧只是一个研究平台,受限于有些凌乱和脆弱的液压肌肉。

关键词：人形机器人搬运机器人四足机器人 Atlas 资金雄厚电动化液压系统波士顿

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人形机器人之年

科技纵览 2024年第1期 44-47,58页

作者： evan Ackerman 不详

10年前,在迈阿密附近举行的美国国防部高级研究计划局(DARPA)机器人挑战赛(DRC)试点活动上,我看到了有史以来最先进的人形机器人在模拟福岛核灾难的场景下挣扎前行。一组经验丰富的工程师控制着每个机器人,机器人头顶有防止它们摔倒的... 详细信息

10年前,在迈阿密附近举行的美国国防部高级研究计划局(DARPA)机器人挑战赛(DRC)试点活动上,我看到了有史以来最先进的人形机器人在模拟福岛核灾难的场景下挣扎前行。一组经验丰富的工程师控制着每个机器人,机器人头顶有防止它们摔倒的安全绳。这些机器人必须展示出机动性、感知能力和操控能力,虽然它们的动作缓慢而艰难,但它们做到了。

关键词：人形机器人高级研究计划局美国国防部安全绳挑战赛感知能力迈阿密

Neonatal Direct Rigid Laryngoscopy and Bronchoscopy: A Near Miss

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Open Journal of Anesthesiology 2024年第4期14卷 126-130页

作者： Dennis E. Feierman Mark Kronenfeld Jacob Sutton Gil Zoizner evan P. Salant Department of Anesthesiology Maimonides Medical Center New York USA Rutgers Robert Wood Johnson University Hospital New Brunswick USA Meir Hospital Clalit Health Services Kefar Sava Israel

Airway management is a skill necessary for healthcare providers who manage patients. Intubation is a skill that both anesthesiologists and intensivists use daily. We present a case of a neonate that developed significant worsening stridor after a successful intubation for a hernia repair. After 4 intubation attempts, with easy visualization of the vocal cords and unsuccessful placement of the endotracheal tube, the patient was emergently brought to the operating room for evaluation.

关键词： Neonate Direct Laryngoscopy Intubation

Evaluation of Serum Anti-Müllerian Hormone (AMH) Values for 28,016 Bulgarian Women: Prognostic Statistical Model of Age Specific AMH Declining

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Open Journal of Obstetrics and Gynecology 2024年第5期14卷 651-673页

作者： Martin Vladimirov evan Gatev Desislava Tacheva Aleksandra Kalacheva Milena Bojilova Serpil Izet Alexander Angelov Nedyalko Kalatchev Iavor K. Vladimirov Sbalagrm-Sofia Sofia Bulgaria Bulgarian Academy of Science Institute of Molecular Biology Sofia Bulgaria Department of Cytology-Histology and Embryology Sofia University &#8220St. Kliment Ohridski&#8221 Sofia Bulgaria Cibalab Boulevard &#8220Akademik Ivan Evstratiev Geshov&#8221 Sofia Bulgaria Synevo Bulgaria Sofia Bulgaria

The present study aims to establish a relationship between serum AMH levels and age in a large group of women living in Bulgaria, as well as to establish reference age-specific AMH levels in women that would serve as an initial estimate of ovarian age. A total of 28,016 women on the territory of the Republic of Bulgaria were tested for serum AMH levels with a median age of 37.0 years (interquartile range 32.0 to 41.0). For women aged 20 - 29 years, the Bulgarian population has relatively high median levels of AMH, similar to women of Asian origin. For women aged 30 - 34 years, our results are comparable to those of women living in Western Europe. For women aged 35 - 39 years, our results are comparable to those of women living in the territory of India and Kenya. For women aged 40 - 44 years, our results were lower than those for women from the Western European and Chinese populations, close to the Indian and higher than Korean and Kenya populations, respectively. Our results for women of Bulgarian origin are also comparable to US Latina women at age 30, 35 and 40 ages. On the base on constructed a statistical model to predicting the decline in AMH levels at different ages, we found non-linear structure of AMH decline for the low AMH 3.5) the dependence of the decline of AMH on age was confirmed as linear. In conclusion, we evaluated the serum level of AMH in Bulgarian women and established age-specific AMH percentile reference values based on a large representative sample. We have developed a prognostic statistical model that can facilitate the application of AMH in clinical practice and the prediction of reproductive capacity and population health.

关键词： Anti-Müllerian Hormone Women Age Ovarian Response Ethnicity Prognostic Statistical Model