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Managing Traumatic Stress Using a Mental Health Care Mobile App: A Pilot Study

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International Journal of Mental Health Promotion 2021年第3期23卷 385-393页

作者： Yun-Jung choi eun-jung Ko eun-Joo choi Youn-Joo Um Red Cross College of Nursing Chung-Ang UniversitySeoul156-756Korea Graduate School of Nursing Chung-Ang UniversitySeoul156-756Korea

This study aims to contribute to improving mental health services and establishing a direction for disaster survivors by verifying the effectiveness of the TLS(Training for Life Skills)app,a mental health management mobile ***,22 disaster survivors received access to the app(with guidance)for eight weeks;we analyzed its effectiveness by examining each participant’s electroencephalography data,which were collected while they were utilizing the *** results of this study show that the use of the TLS app had a significant positive effect on emotional quotient,basic rhythm quotient(left brain,right brain),alpha blocking rate(left brain,right brain),and brain quotient of disaster *** TLS mobile app is expected to not only provide psychological first aid to disaster survivors but also to improve their life skills,which may allow them to gain information about their emotions;hence,it may provide the appropriate conditions needed to enable effective self-control and health management for disaster survivors.

关键词： Mobile applications trauma disasters mental health

How to improve patient satisfaction during midazolam sedation for gastrointestinal endoscopy?

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World Journal of Gastroenterology 2017年第6期23卷 1098-1105页

作者： eun Hyo Jin kyoung Sup Hong Young Lee Ji Yeon Seo Ji Min choi Jaeyoung Chun Sang Gyun Kim Joo Sung Kim Hyun Chae Jung Department of Internal Medicine Healthcare Research InstituteSeoul National University Hospital Healthcare System Gangnam Center Department of Internal Medicine Liver Research InstituteSeoul National University College of Medicine Department of Biostatistics and Bioinformatics Healthcare Research InstituteSeoul National University Hospital Healthcare System Gangnam Center

To determine the procedure-related factors that affect sedation satisfaction and to make a suggestion to improve *** prospectively enrolled a total of 456 patients who underwent outpatient endoscopy procedures with midazolam sedation between March 2014 and August 2014. All patients completed both pre- and post-endoscopy questionnaires about sedation expectations and *** study cohort included 167 (36.6%) patients who underwent esophagogastroduodenoscopy (EGD), 167 (36.6%) who underwent colonoscopy, and 122 (26.8%) who underwent a combined procedure (EGD and colonoscopy). Over 80% of all patients were satisfied with sedation using midazolam. In univariate and multivariate analyses, total procedure time in the EGD group, younger age (≤ 50 years), and longer colonoscopy withdrawal time in the colonoscopy group were related to decreased satisfaction with sedation. However, in active monitoring and intervention group, there was no decrease in grade of satisfaction despite longer procedure time due to more procedures during colonoscopy. Younger age (≤ 50 years), longer inter-procedure time gap, and colonoscopy withdrawal time were related to decreased satisfaction in the combined EGD and colonoscopy *** is still a safe and effective sedative for gastrointestinal endoscopy. Satisfaction with sedation depends on several factors including age (≤ 50 years) and procedure time duration. To improve patient satisfaction with sedation, active monitoring of sedation status by the endoscopist should be considered for patients who require long procedure time.

关键词： Conscious sedation Patient satisfaction Endoscopy Midazolam Surveys and questionnaires

Comparative effects of plant oils and trans-fat on blood lipid profiles and ischemic stroke in rats

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The Journal of Biomedical Research 2017年第2期31卷 122-129页

作者： Haiyu Guo Young-Hwan Ban Yeseul Cha Tae-Su Kim Sung-Pyo Lee eun Suk An Jieun choi Da Woom Seo Jung-Min Yon Ehn-kyoung choi Yun-Bae Kim Veterinary Medical Center and College of Veterinary Medicine Chungbuk National University Cheongiu Chungbuk Republic of Korea Anydoctor Healthcare Co. Ltd. Cheonan Chungnam Republic of Korea

Since plant oils are believed to be better than animal fats for cerebrovascular and cardiovascular diseases, the effects of various plant oils and trans-fat on blood lipid profiles and ischemic stroke were investigated. Sprague- Dawley rats were fed a diet containing the oils or trans-fat, and then body weights, blood lipids, and effects on brain infarction and physical dysfunction induced by middle cerebral artery occlusion （MCAO） were analyzed. All the oils and trans-fat, except perilla oil, significantly increased body fats and body weight gain. Sesame oil and trans-fat specifically increased blood cholesterols and triglycerides, respectively, while perilla oil decreased both cholesterols and triglycerides. Perilla oil not only attenuated cerebral infarction, but also restored locomotor activity and rota-rod performances of MCAO rats. It is suggested that perilla oil among oils and fats could be the first choice to reduce the risk of metabolic syndrome and ischemic stroke.

关键词： plant oil trans-fat blood lipid body fat ischemic stroke physical activity

The Western Model of Integrative Oncology-the Contribution of Chinese Medicine

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Chinese Journal of Integrative Medicine 2012年第9期18卷 643-651页

作者： Gustav J.Dobos Barbara Kirschbaum Kyung-eun choi Department of Internal and Integrative Medicine Kliniken Essen-MitteAcademic Teaching Hospital of the University of Duisburg-Essen Am Deimelsberg 34 a45276 EssenGermany Mamma Center Hamburg Jerusalem HospitalMoorkamp 2-620357 HamburgGermany

Western integrative oncology （IO） combines conventional mainstream medicine with complementary and alternative medicine （CAM） for the care of cancer patients. Since it includes patient orientation and the holistic approach of many CAM options, IO offers not only preventive measures, but also a wide spectrum of treatment modalities for all stages of illness, from the acute phases through the rehabilitation period. Many therapeutic methods of IO are supported by scientific evidence, for example, dietary and nutritional counseling, exercise, and mind-body medicine, among others. IO also includes therapeutic interventions of traditional Chinese medicine （TCM）. At present acupuncture, qigong, and foot massage play an important role in the Western care of cancer patients. However, unlike in China, in Western countries herbal remedies are usually only used during those periods in which chemotherapy is not applied in order to avoid herb-drug interactions. Instead,acupuncture is widely used to manage the side-effects that often accompany chemotherapy. This paper focuses on the role of Chinese medicine in Western IO and reviews the scope and limitations of IO in the care of cancer patients today. The future challenges of IO will also be discussed in this paper.

关键词： integrative oncology integrative medicine complementary and alternative medicine traditional Chinese medicine

Delayed inflammatory response evoked in nasal alloplastic implants after COVID-19 vaccination: A case report

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World Journal of Clinical Cases 2022年第23期10卷 8298-8303页

作者： Min-Gi Seo eun Kyung choi Kyu Jin Chung Department of Plastic and Reconstructive Surgery College of MedicineYeungnam UniversityDaegu 42415South Korea Department of Anesthesiology and Pain Medicine College of MedicineYeungnam UniversityDaegu 42415South Korea

BACKGROUND Delayed inflammatory reactions(DIRs)in alloplast rhinoplasty are a rare complication that may occur several months to years after *** exact causes and mechanisms are unclear,but several triggering factors,including infections,trauma,dental procedures,and vaccination,have been *** SUMMARY A 39-year-old male patient who had undergone augmentation rhinoplasty 8 years ago had DIRs after the administration of the first dose of the mRNA Pfizer coronavirus disease 2019(COVID-19)*** suddenly had tender,erythematous swelling on his face 6 d after *** there was no improvement in the patient’s condition after the conservative treatment,surgical removal of an alloplastic nasal implant was *** after the surgery,the DIRs and accompanying symptoms ameliorated rapidly.A histological study conducted during surgery was fibrosis and small fragments of the hyaline *** The correlation between DIRs and COVID-19 vaccination has not been reported yet and the exact mechanism is *** the uncontrolled inflammatory reactions on the nose leave serious sequelae,surgeons should be conscious of the correlation between COVID-19 vaccines and DIRs associated with nasal alloplastic *** further histological or microbiological studies should be performed to determine the cause of DIRs.

关键词： Delayed inflammatory reactions Alloplast rhinoplasty Silicone COVID-19 Vaccination Case report

Installing a molecular truss beam stabilizes MOF structures

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npj Computational Materials 2022年第1期8卷 1110-1118页

作者： Hong Ki Kim Jong-Yeong Jung Gyumin Kang Mu-Hyun Baik eun-Young choi Department of Chemistry Korea Advanced Institute of Science and Technology(KAIST)Daejeon34141Republic of Korea Center for Catalytic Hydrocarbon Functionalizations Institute for Basic Science(IBS)Daejeon34141Republic of Korea Korea Science Academy of KAIST 105-47 Baegyanggwanmun-roBusanjin-guBusan47162Republic of Korea

Enhancing the stability and durability of metal-organic frameworks(MOFs)is vital for practical applications because many promising MOF materials suffer from phase transitions and/or structural decompositions with humidity being a particularly damaging *** mechanical engineering,the frame of buildings and furniture can be stabilized significantly by installing a truss *** the same principle,we functionalized the organic component of MOF-5 to contain a carbazole moiety that can act as a molecular truss beam by reaching across the corner and forming a stableπ–πinteraction with a phenyl group on the edge position of the *** structural support enhanced the stability of the MOF substantially,allowing the designed MOF to maintain compositional integrity under steam conditions at 90℃for~5 *** unmodified MOF-5 shows clear signs of structural collapse after~1 h.

关键词： beam moiety durability

Role of debris flow on the change of^10Be concentration in rapidly eroding watersheds:a case study on the Seti River,central Nepal

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Journal of Mountain Science 2017年第4期14卷 716-730页

作者： KIM Dong eun SEONG Yeong Bae choi Kwang Hee YU Byung Yong Dept.of Geography Korea UniversitySeoul 02841Korea Yeongsan River Basin Environmental Office Ministry of EnvironmentGwangju 61945Korea Korea Institute of Science and Technology Seoul 02792Korea

The concentration of cosmogenic loBe in riverine sediments has been widely used as a proxy for catchment-wide denudation rate （CWDR）. One of the key assumptions of this approach is that sediments originating from sub-basins with different erosional histories are well mixed. A tragic debris flow occurred in the Seti River watershed, central Nepal, on May 5, 2012. This catastrophic debris flow was triggered by slope failure on the peak of Annapurna IV and resulted in many casualties in the lower Seti Khola. However, it provided an opportunity to test the assumption of equal mixing of sediments in an understudied rapidly eroding watershed. This study documents the CWDR of ^10Be to evaluate the extent of the influence of episodic erosional processes such as debris flow on the spatio-temporal redistribution of loBe concentrations. Our data show that the debris flow caused little change in CWDR across the debris flow event. In addition to isotopic measurement, we calculated denudation rates by using the modeled concentrations in pre- and post-landslide sediments based on the local ^10Be production rate. The modeled result showed little change across the event, indicating that the debris flow in May 2012 played a minor role in sediment evacuation, despite the rapid erosion in the catchment. Our study concludes that although the 2012 event caused many casualties and severe damage, it was a low-magnitude, high frequency event.

关键词： Seti River Beryllium-10 (^10Be) Catchment-wide denudation rate (CWDR) Debrisflow Episodic erosional processes

3D engineered tissue models for studying human-specific infectious viral diseases

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Bioactive Materials 2023年第3期21卷 576-594页

作者： Kyeong Seob Hwang eun U Seo Nakwon choi Jongbaeg Kim Hong Nam Kim Brain Science Institute Korea Institute of Science and Technology(KIST)Seoul02792Republic of Korea School of Mechanical Engineering Yonsei UniversitySeoul03722Republic of Korea Yonsei-KIST Convergence Research Institute Yonsei UniversitySeoul03722Republic of Korea Division of Bio-Medical Science&Technology KIST SchoolKorea University of Science and Technology(UST)Seoul02792Republic of Korea KU-KIST Graduate School of Converging Science and Technology Korea UniversitySeoul02841Republic of Korea

Viral infections cause damage to various organ systems by inducing organ-specific symptoms or systemic multi-organ *** on the infection route and virus type,infectious diseases are classified as respiratory,nervous,immune,digestive,or skin *** these infectious diseases can widely spread in the com-munity and their catastrophic effects are severe,identification of their causative agent and mechanisms un-derlying their pathogenesis is an urgent *** infection-associated mechanisms have been studied in two-dimensional(2D)cell culture models and animal models,they have shown limitations in organ-specific or human-associated pathogenesis,and the development of a human-organ-mimetic system is ***,three-dimensional(3D)engineered tissue models,which can present human organ-like physiology in terms of the 3D structure,utilization of human-originated cells,recapitulation of physiological stimuli,and tight cell–cell interactions,were ***,recent studies have shown that these models can recapitulate infection-associated *** this review,we summarized the recent advances in 3D engineered tissue models that mimic organ-specific viral ***,we briefly described the limitations of the current 2D and animal models in recapitulating human-specific viral infection ***,we provided an overview of recently reported viral infection models,focusing particularly on organ-specific infection ***,a future perspective that must be pursued to reconstitute more human-specific infectious diseases is presented.

关键词： 3D engineered tissue model Infectious viral disease Infection route Pathology In vivo-mimicking

Association between the early high level of serum tacrolimus and recurrence of hepatocellular carcinoma in ABO-incompatible liver transplantation

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World Journal of Gastrointestinal Surgery 2023年第12期15卷 2727-2738页

作者： Ji Won Han Jong Young choi eun Sun Jung Ji Hoon Kim Hee Sun Cho Jae-Sung Yoo Pil Soo Sung Jeong Won Jang Seung Kew Yoon Ho Joong choi Young kyoung You Department of Internal Medicine The Catholic University of KoreaSeoul 06591South Korea The Catholic University Liver Research Center College of MedicineThe Catholic University of KoreaSeoul 06591South Korea Department of Hospital Pathology The Catholic University of KoreaSeoul 06591South Korea Department of Surgery The Catholic University of KoreaSeoul 06591South Korea

BACKGROUND Clinical factors predicting graft survival(GS)after ABO-incompatible(ABOi)liver transplantation(LT),and differences between recipients with and without hepatocellular carcinoma(HCC)are *** To analyze the impact of serial serum tacrolimus trough concentration in recipients with or without(HCC)in ABOi living-donor liver transplantation(LDLT).METHODS We analyzed a historical cohort of 89 recipients who underwent ABOi LDLT,including 47 patients with *** The 1-,3-,5-,and 10-year GS rates were 85.9%,73.3%,71.4%,and 71.4%,respectively,and there were no significant differences between HCC and non-HCC *** multivariate Coxregression analyses,tacrolimus trough concentrations below 5.4 ng/mL at 24 wk post-LT,in addition to the antibody-mediated rejection(AMR)were associated with poor-graft *** HCC patients,AMR[hazard ratio(HR)=63.20,P7.3 ng/mL were significant predictive factors for HCC *** propensity score matching,patients with high tacrolimus concentrations at 4 wk had significantly poor recurrence-free *** Elevated tacrolimus levels at 4 wk after ABOi LDLT have been found to correlate with HCC ***,careful monitoring and control of tacrolimus levels are imperative in ABOi LT recipients with HCC.

关键词： ABO-incompatible Liver transplantation Tacrolimus Hepatocellular carcinoma