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In Vitroand in VivoEfficacy of an Experimental Compound against Rhipicephalus (Boophilus) microplusTicks

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pharmacology & pharmacy 2013年第1期4卷 41-45页

作者： Guadalupe Santillán-Velazquez Froylán Ibarra-Velarde Blas flores p.rez Margarita Romero-Avila Yazmin Alcalá-Canto Héctor Salgado-Zamora Yolanda Vera Montenegro Department of parasitology Veterinary Faculty of Medicin and Zootechnics National University Autonomus of Mexico Mexico City Mexico Faculty of Chemistry National University Autonomus of Mexico Mexico City Mexico Laboratory of Organic Chemistry School of Biological Sciences National Politechnic Institute Mexico City Mexico

The aim of the present study was to evaluate the ixodicide efficacy of the experimental compound 712-BF-016 against Rhipicephalus (Boophilus) microplus ticks in vitro and in cattle. The in vitro efficacy was initially tested against R. Boophilus microplus larvae using the Larval packet Test (LpT). In a 2nd study the ixodicide efficacy was tested against adult ticks using the Adult Inmersion Test (AIT). Finally, a field test with the compound was carried out using 24 steers experimentally infested with R. (Boophilus) microplus ticks which were divided into 4 groups of 6 animals each for treatment. Groups 1 and 2 received the experimental compound at concentrations of 16% and 20%, respectively, which were applied as an aspersion in a total volume of 4 liters/animal. Group 3 was equally treated but with a commercial ixodicide containing cipermethrin at a 16% concentration. Group 4 served as untreated control. The efficacy was measured on days 1, 2, 3 after treatment as the percentage of ticks present from the treated groups, relative to the ticks present in the untreated control. The results indicated a percentage mortality of 93.21% for LpT and 98.02% for AIT. The efficacy produced in cattle was 61.78%, 76.43% and 85.34% for groups 1, 2 y 3, respectively. It is concluded that there was no concordance between the results obtained in vitro with those found in cattle. possibly the excipient used for the formulation of the experimental compound was not suitable and had some influence on the results.

关键词： Rhipicephalus (Boophilus) microplus Ixodicide LpT AIT Cattle

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Genotoxic and Cytotoxic Damage by Cyclophosphamide and Adriamycin as a Response to Treatment in Breast Cancer patients: pilot Study

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Journal of Cancer Therapy 2015年第2期6卷 163-168页

作者： Jimena Garibay-Garcia Fernando Mejia-Sanchez Eduardo Ramírez-San-Juan Miriam V. flores-Merino Julieta Castillo-Cadena Research Center in Medical Science Autonomous University of the State of Mexico Toluca Mexico National School in Biological Science Instituto Politécnico Nacional Mexico City Mexico

The aim of this study was to evaluate the genotoxicity induced by cyclophosphamide-adriamycin treatment in breast cancer patients through the frequencies of Sister Chromatid Exchange (SCE), Replication Index (RI), Mitotic Index (MI) and Cell proliferation Index (CpI) and to study the possible association between biomarkers of genotoxicity and the early response to treatment. The frequencies were obtained before and immediately after therapy from 17 patients with breast cancer (p ponse to treatment was assessed after two years resulting in 12 patients in a state of remission. MI and CpI had high values after treatment in women with active cancers compared to those in a state of remission, however there were not significant differences. Conclusions: It is possible that MI y CpI biomarkers can serve as indicators for early assessment of treatment with cyclophosphamide-adriamycin. It should be noted that these are preliminary results and further study is necessary.

关键词： Sister Chromatid Exchange Genotoxicity Biomarkers Breast Cancer Cyclophosphamide Adriamycin

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增强式训练对下肢肌构筑、肌腱结构、刚度和体能表现的影响:系统综述和meta分析

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中国体育教练员 2022年第4期30卷 24-24,71页

作者：邓鉴峰(译) RAMírez-DELACRUZ M BRAVO-SáNCHEZ A esteban-GARCíA p 上海体育学院上海200438 不详

增强式训练(plyometric training)是一种提高专项运动表现的力量训练方法。增强式训练的动作通常包括3个阶段:预先拉长阶段(离心收缩阶段),离心-向心过渡阶段(等长收缩阶段)和主动收缩阶段(向心收缩阶段)。在预先离心拉长阶段,肌腱被拉... 详细信息

增强式训练(plyometric training)是一种提高专项运动表现的力量训练方法。增强式训练的动作通常包括3个阶段:预先拉长阶段(离心收缩阶段),离心-向心过渡阶段(等长收缩阶段)和主动收缩阶段(向心收缩阶段)。在预先离心拉长阶段,肌腱被拉长产生保护性抑制的同时,有利于存储更多的弹性势能,而在由离心收缩到向心收缩的过程中,肌腱所储存的弹性势能由肌腱传导至骨骼肌。

关键词： meta分析保护性抑制离心收缩下肢肌向心收缩等长收缩主动收缩弹性势能

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Forecast of the Luminescent phenomena of Silicon Rich Oxide Films off Stoichiometry by Means of the Global Reaction Model

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Journal of Modern physics 2015年第11期6卷 1679-1694页

作者： Néstor David Espinosa-Torres José álvaro David Hernández de la Luz José Francisco Javier flores-Gracia José Alberto Luna-López Javier Martínez-Juárez Gregorio flores-Carrasco IC-CIDS Benemérita Universidad Autónoma de puebla Puebla México Ex Graduate Research Trainee at plasma processing Laboratory Chemical Engineering Department McGill University Montreal Canada Department of Materials Science and Engineering and Chemical Engineering University Carlos III of Madrid and IAAB Madrid Spain

The Global Reaction Model describes a set of chemical reactions that can potentially occur during the process of obtaining silicon rich oxide (SRO) films, regardless of the technique used to grow such films which are an outside stoichiometry material. particularly, chemical reactions that occur during the process of growing of SRO films by LpCVD technique are highlighted in this model. We suggest and evaluate either some types of molecules or resulting nanostructures and we predict theoretically, by applying the density functional theory, the contribution that they may have to the phenomenon of luminescence which is measured in SRO films. Also, we have calculated the opto-electronic properties of SRO films. The suggested model provides enough information required to identify the molecular structures resulting from the presence of defects in SRO films and also those corresponding to charged structures. It is also possible to detect the molecular structures which are modified due to the effect of heat treatment, and identify the presence of different oxidation states inclusive the formation of siloxanes.

关键词： Global Reactions Model Silicon Rich-Oxide Defects LpCVD Luminescence

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Mollusk Species Richness on the Rocky Shores of the State of Guerrero, Mexico, as Affected by Rains and Their Geographical Distribution

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Natural Resources 2012年第4期3卷 248-260页

作者： flores-Rodríguez pedro flores-Garza Rafael García-Ibánez Sergio Valdés-González Arcadio Violante-González Juan Santiago Cortés Enedina Galeana-Rebolledo Lizeth Torreblanca-Ramírez Carmina Unidad Académica de Ecología Marina Universidad Autónoma de Guerrero Acapulco México Universidad Autónoma de Nuevo León Laboratorio de Acuacultura Facultad de Ciencias Biológicas Ciudad Universitaria San Nicolás de los Garza México

Natural processes in ecosystems shows significant variations in species richness with regular cycles that can be altered by natural or anthropogenic activities;the present research was in order to understand on some of these variations. The objectives were: 1) determine the species richness of rocky intertidal mollusks;2) track their geographical distribution at State level;and 3) determine the changes in species richness as a result of rainfall on an annual cycle. For these purposes it was sampled in March, June, September and December 2005, the sampled area was 20 m2for each collecting site;the sampling unit was a pVC rectangle frame one by two meter per side. The mollusks found within the sampling units were collected, identified and counted. The species distribution was analyzed by sites and regions, considered species richness per season, and the distributional patterns by rainy season historical records. A total of 62 mollusks species were found, its richness associated with substrate stability and wave intensity on each site, Gastropods had the highest species richness. When analyzing the regional distribution and sites, it was found a pattern of species richness roughly constant in the proportion of species with wide distribution (generalists) versus those of restricted spatial representation (specialists). Gastropods had the highest number of species with restricted spatial representation. Seasonal rainfall differences did not quantitatively altered on the overall the species of mollusks in the rocky intertidal sampled zone however, in the analysis per Class, Gastropoda indicated changes in species richness influenced by rainfall, which were not observed in Bivalvia and polyplacophora, suggesting that those changes might depend on adaptive processes or the lack of adaptation of gastropod species to the characteristics of the rocky intertidal habitat.

关键词： Rocky Shore Species Richness Geographic Distribution Rain Effects Mollusks

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Interaction Between Heficoverpa zea Damage with Corncob Diseases on Genetically Modified Corn in Sinaloa, México

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Journal of Life Sciences 2014年第4期8卷 329-334页

作者： Luis A. Aguirre Uribe Gustavo A. Frías Trevino Agustín Hernández Juárez Mariano flores Davila Emesto Cerna Chavez Jerónimo Landeros flores Yisa M. Ochoa Fuentes plant Health Department Universidad A utónoma Agraria Antonio Narro Buenavista Saltillo 25315 Coahuila México

GM （genetically modified） corn with the CrylAb, mCry3A and Vip3Aa20 protein of Bt （Bacillus thuringiensis） and its respective isoline as control with and without chemical control for corn earworm were used in this research. Fusarium corncob damage was lower on GM corn with （12.5%） and without （25.7%） insecticide treatment as compared with the isoline that had 48.3% and 83.1% of damaged corncobs with and without chemical control, respectively. Corn smut cob damage was also lower on GM corn with （3.2%） and without （6.3%） insect control compared with 15.5% and 49.7% damage with and without insecticide treatment, respectively. Fusarium sp. corncob rot was also lower on GM corn with 5.7% and 9.5% whereas a 24.6% and 63% rot was observed on the isoline with and without insecticide control, respectively. Ustilago maydis severity was also lower on Bt corn finding 0.07% and 0.25% damage on treatments with and without insect control as compared with the isoline that showed an 11.6% and a 41.4% smut rot with and without insecticide treatment, respectively. The authors conclude that GM corn resistant to Helicoverpa zea prevents damage by the pest, eliminating the entrance pathway for Fusarium sp. and Ustilago maydis.

关键词： Bacillus thuringiensis transgenic Fusarium Ustilago maydis mycotoxins corn smut.

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Soil Carbon Storage in Experimental Forest plantations with Tropical Species

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Open Journal of Forestry 2022年第1期12卷 1-18页

作者： Celia De La Mora-Orozco José Germán flores Garnica Irma Julieta González Acuña Juan De Dios Benavides Solorio César S. Magaña Martínez Laura Izascum p.rez Valencia Instituto Nacional de Investigaciones Forestales Agrícolas y Pecuarias Tepatitlán México Instituto Nacional de Investigaciones Forestales Agrícolas y Pecuarias Guadalajara México Instituto Nacional de Investigaciones Forestales Agrícolas y Pecuarias Santiago Ixcuintla México Instituto Tecnológico José Mario Molina pasquel y Henríquez Unidad Académica Arandas Arandas México

Forest ecosystems represent a third of the total organic carbon (TOC) stored in the soil. However, studies still need to be carried out to generate reliable information on its soil carbon storage potential in an experimental plantation. Therefore, the objective of this research was to determine the storage of total organic carbon (TOC) in the soil in two experimental forest plantations with tropical species, located in the state of Nayarit, México. The research was carried out in two experimental plantations with tropical species, located at the Santiago Ixcuintla Experimental Field (CESIX) and at the El Verdine?o Experimental Site (SEEV). The established species are Swietenia macrophylla King (mahogany), Cedrela odorata L. (cedar) and Tabebuia rosea Bertoil (pink trumpet-tree). In addition, data from dasometric variables were used in order to define if any of these variables had a similar variation to the soil TOC stock by species. The sampling was done under a randomized block experimental design in each experimental forest plantation (CESIX and SEEV). Nine composite samples were collected in the soil under the tree species at a depth of 0 - 30 cm, and 1.5 m distance from the tree. To determine the soil TOC, an elemental analyzer with a thermal conductivity detector Thermo Scientific (Flash 2000) was used. The results showed that TOC presented mean values of 103.60 and 219.98 t·hap>-1p> at a depth of 0 - 30 cm in CESIX and SEEV respectively. The highest TOC waspan>pan>pan>pan>pan style="font-family:;" "=""> obtained in soil under mahogany;142.95 t·hap>-1p> in CESIX and 284.41 t·hap>-1p> in SEEV. The analysis of the differences in TOC between the two plantations was highly significant. In the analysis of the species, it showed a statistically significant difference (p < 0.0001), defining that the soil unde

关键词： Carbon Sequestration Dasometric Variables Tropical Trees

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Isolation and Characterization of Mercury Resistant Trichoderma Strains from Soil with High Levels of Mercury and Its Effects on Arabidopsis thaliana Mercury Uptake

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Advances in Microbiology 2018年第7期8卷 600-613页

作者： JoséLuis Hernández-flores JoséGerardo Bernal Melo Andrés Cruz Hernández Miguel A.Ramos López Carlos Saldana Gutiérrez Sergio Romero Gomez Victor p.rez Moreno Rosa p.Calvillo Medina JoséHumberto Valenzuela Soto Sergio pacheco Hernández George H.Jones Sergio Casas flores Juan Campos-Guillen Laboratorio de Bioseguridad y Análisis de Riesgo Departamento de Ingeniería Genética de PlantasCentro de Investigación y de Estudios Avanzados del IPNIrapuatoGto.México Facultad de Química Universidad Autónoma de QuerétaroCerro de las Campanas s/nQuerétaroQro.México Escuela de Agronomía Universidad De La Salle Bajíocampus Campestre.LeónGto.México Facultad de Ciencias Naturales Universidad Autónoma de QuerétaroAv.De las Ciencias S/NQuerétaroQro.México Centro de Investigación en Química Aplicada Blvd.Enrique Reyna Hermosillo No.140SaltilloCoahuilaMéxico Department of Biology Emory UniversityAtlantaGeorgiaUSA IpICYT División de Biología Molecular.Camino a la presa San JoséNo.2055Colonia Lomas 4a sección.C.P.San Luis PotosíMexico

Traditional mining activities are usually correlated with high levels of soil pollution, which is a major environmental concern. Extensive mining activities have taken place in the San Joaquin region in the State of Querétaro, México resulting in high levels of mercury soil pollution (up to 1532 ± 300 mg/kg). We isolated mercury-resistant fungal strains from the San Joaquin region soils and identified them through morphologic characteristics and ITS rDNA region sequence analysis. We determined that fungi isolated belong to the genus Trichoderma. All the isolates selected showed the ability to catalyze the volatilization of Hg. For air sampling, an active sampling device was constructed and using acid KMnO4 as an absorbent, the concentration of mercury in solution was determined through the cold vapor atomic absorption method. The results show mercury volatilization from the fungal species assay, with a maximum of 213.04 ± 32.6 μg/m3 while mycelium accumulation ranged from less than 17.5 ± 2.9 to 20.0 ± 3.4 μg/g. The fungal isolates were also evaluated for their ability to reduce mercury uptake in Arabidopsis thaliana. These observations suggest the utility of Trichoderma for the mobilization of mercury in those contaminated soils.

关键词： Volatilization Mercury Trichoderma Soil Bioremediation

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Differential Effect on Two Immobility Responses by Chronic Administration of 1,3-di-o-Tolyl-Guanidine (Sigma Receptor Agonist) in Rats with Neonatal Ventral Hippocampal Lesion

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pharmacology & pharmacy 2014年第7期5卷 681-690页

作者： Blanca Estela Jaramillo Fidel De la Cruz Genaro Vargas Oscar O. Morales Gonzalo flores Sergio R. Zamudio Linda Garcés-Ramírez Departamento de Fisiología Escuela Nacional de Ciencias Biológicas Instituto Politécnico Nacional México D. F. México Instituto de Fisiología Benemérita Universidad Autónoma de Puebla Puebla México programa Educativo de la Ingeniería en Biotecnología Universidad Politécnica de Pachuca Zempoala Hidalgo México

The effect of chronic administration of the sigma agonist: 1,3-di-o-tolyl-guanidine (DTG), in neonatal ventral hippocampal lesioned (nVHL) rats, on the immobility by clamping and dorsal immobility, were investigated. The nVHL increases the duration of immobility by clamping, but does not affect the duration of the dorsal immobility. We found that DTG augments the duration of the dorsal immobility in the unlesioned rats, but does not modify the duration of immobility induced by clamping the neck. DTG also counteracts the increase in the duration of the immobility by clamping produced by nVHL. However, the increase in the duration of the dorsal immobility produced by DTG is counteracted by nVHL. These results are discussed with respect to the differential effect on the two immobility responses tested, suggesting that they are different forms of immobility mediated by different mechanisms although they behaviorally share common characteristics.

关键词： Immobility Response Sigma Receptor DTG Schizophrenia Neonatal Ventral Hippocampal Lesion

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Bismuth Oxide Carbonate Structures Synthesized by Microwave—Assisted Solvothermal Approach and Its Use as Catalyst for the Degradation of Azo Dye in a Solution

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Journal of Minerals and Materials Characterization and Engineering 2019年第6期7卷 468-479页

作者： M. A. Luna-Alvarado M. Estrada-flores M. E. Manríquez-Ramírez C. M. reza-San Germán Departamento de Ingeniería Química Industrial Escuela Superior de Ingeniería Química e Industrias Extractivas Instituto Politécnico Nacional Ciudad de México México

Because the textile industry wastewater is polluted with azo dyes, and in order to improve a process of wastewater remediation, the synthesized sample was evaluated in the photocatalysis of methylene blue and compared with commercial Bi2O3 and anatase TiO2. Structures of bismuth oxide carbonate (Bi2O2CO3) were successfully synthesized using a solution at 0.03 M concentration of sodium bismuthate as precursor and ethylene glycol as dissolvent by solvothermal microwave-assisted approach. The semiconductor catalyst samples were characterized by X-ray diffraction (XDR), scanning electron microscope (SEM) and Brunauer-Emmett-Teller analysis (BET). The application of the synthesized sample as catalyst, obtained a 68% of degradation. This result is better than the commercial Bi2O3 and close to the anatase TiO2 degradation. This sample shows a variation in the formula (with the presence of carbonates) but also shows an acceptable degradation percentage according to TiO2 results, making Bi2O2CO3 a possible substitute of TiO2.

关键词： Carbonate Bismuth Oxide photocatalysis Microwave-Solvothermal Synthesis Methylene Blue Degradation

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