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Eye and Vision 2021年第2期8卷 67-74页

作者： Mehmet Fuat Alakus Mehtap Caglayan Nazım Ekin Hasan Oncul esref arac Umut Dag Halit Diri Department of Ophthalmology University of Health SciencesDiyarbakir Gazi Yasargil Research and Training HospitalDiyarbakırTurkey Department of Internal Medicine University of Health SciencesDiyarbakir Gazi Yasargil Research and Training HospitalDiyarbakırTurkey

Background:To investigate the topographic measurements and densitometry of corneas in Wilson’s disease(WD)patients with or without a Kayser-Fleischer ring(KF-r)compared to healthy ***:This cross-sectional study included 20 WD patients without a KF-r(group I),18 WD patients with a KF-r(group II),and 20 age-matched controls(group III).The Pentacam high resolution imaging system is used to determine corneal topographic measurements and ***:Mean age for groups I,II and III was 25.40±6.43 years(14-36 years),25.38±6.96 years(16-39 years),23.60±6.56 years(17-35 years),respectively(P=0.623).There was no significant difference between the groups in terms of the anterior corneal densitometry values(P>0.05),while the 6-10mm and 10-12 mm mid stroma and the 2-6 mm,6-10 mm,and 10-12 mm posterior corneal densitometry values in group II were significantly higher than those in groups I and III(for all values,Paracentral cornea.

关键词： Wilson Kayser-Fleischer ring Corneal densitometry

Monte Carlo calculations of the incineration of plutonium and minor actinides of laser fusion inertial confinement fusion fission energy (LIFE) engine

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Plasma Science and Technology 2018年第7期20卷 159-165页

作者： adem acir esref baysal gazi university faculty of technologydepartment of energy systems engineeringTeknikokullarAnkaraTurkey manisa celal bayarüniversitesi hasan ferdi turgutlu faculty of technology department of energy systems engineeringManisaTurkey

In this paper, neutronic analysis in a laser fusion inertial confinement fusion fission energy （LIFE） engine fuelled plutonium and minor actinides using a MCNP codes was investigated. LIFE engine fuel zone contained 10 vol% TRISO particles and 90 vol% natural lithium coolant mixture. TRISO fuel compositions have Mod①： reactor grade plutonium （RG-Pu）, Mod②： weapon grade plutonium （WG-Pu） and Mod③： minor actinides （MAs）. Tritium breeding ratios （TBR） were computed as 1.52, 1.62 and 1.46 for Mod（D, Mod② and Mod③, respectively. The operation period was computed as ~21 years when the reference TBR 〉 1.05 for a self- sustained reactor for all investigated cases. Blanket energy multiplication values （M） were calculated as 4.18, 4.95 and 3.75 for Mod①, Mod② and Mod③, respectively. The bumup （BU） values were obtained as ~1230, ~1550 and ~1060 GWd tM-1, respectively. As a result, the higher BU were provided with using TRISO particles for all cases in LIFE engine.

关键词： fusion nuclear Monte Carlo

Giant saccular aneurysm of the left main coronary artery

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Journal of Geriatric Cardiology 2013年第1期10卷 110-112页

作者： esref Tuncer Ugur Onsel Turk Emin Alioglu Department of Cardiology Central Hospital 2/2 Bayrakli Izmir 35050 Turkey

Coronary aneurysms represent anomalies identified in 0.15%–4.9%of patients undergoing coronary angiography. At present, there is no uniform definition of this pathology. Aneurysms of the left main coronary artery (LMCA) are extremely uncommon, with an incidence of 0.1%. It has been demonstrated that atherosclerosis is the main cause of these anomalies in adults, and Kawasaki disease in children and adolescents. Other causes include connective tissue disorders, trauma, vasculitis, congenital, mycotic, and idiopathic. These dilated sections of the coronary artery are not benign pathology because they are subject to spasm, thrombosis, and subsequent distal embolism, spontaneous dissection and rupture. Treatment options include anticoagulation, custom-made covered stents, reconstruction, resection, and exclusion with bypass. Our report on an old case illustrates the giant saccular LMCA aneurysm leading to myocardial ischemia due to coronary steal phenomenon.

关键词： Coronary aneurysm Coronary angiography Coronary artery disease

Synthesis, Spectroscopic and Electrochemical Investigations of Two vic-Dioximes and Their Mononuclear Ni（Ⅱ）, Cu（Ⅱ） and Co（Ⅱ） Metal Complexes Containing Morpholine Group

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Chinese Journal of Chemistry 2006年第11期24卷 1599-1604页

作者： KILIC, Ahmet TAS, esref GUMGUM, Bahattin YILMAZ, Ismail Department of Chemistry Harran University Sanliurfa 63510 Turkey Department of Chemistry Dicle University Diyarbakir 21280 Turkey Department of Chemistry Technical University oflstanbul Istanbul Maslak 34469 Turkey

Two vic-dioxime ligands （LxH2） containing morpholine group have been synthesized from 4-[2-（dimethylaminoethyl）] morpholine with anti-phenylchloroglyoxime or anti-monochloroglyoxime in absolute THF at -15 ℃. Reaction of two vic-dioxime ligands with MCl2·nH2O （M： Ni, Cu or Co and n=2 or 6） salts in 1 ： 2 molar ratio afforded metal complexes of type [M（LxH）2] or [M（LxH）2·2H2O]. All of metal complexes are non-electrolytes as shown by their molar conductivities （Am） in DMF （dimethyl formamide） at 10^-3 mol·L^-1. Structures of the ligands and metal complexes have been solved by elemental analyses, FT-IR, UV-Vis, ^1H NMR and ^13C NMR, magnetic susceptibility measurements, molar conductivity measurements. Furthermore, redox properties of the metal complexes were investigated by cyclic voltammetry.

关键词： morpholine electrochemistry dioxime structure metal complex cyclic voltammetry

Evaluation of CA125 and NT-proBNP values in patients undergoing transcatheter aortic valve implantation

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Journal of Geriatric Cardiology 2015年第2期12卷 100-106页

作者： Huseyin Ayhan Haca Ahmet Kasapkara Tahir Durmaz Telat Keles Cenk San Serdal Bastug Kemal esref Erdogan Nihal Akar Bayram Emine Bilen Murat Akgay Engin Bozkurt Faculty of Medicine Department of Cardiology Ytldtrtm Beyaztt University Ankara 06800 Turkey Department of Cardiology Ankara Ataturk Education and Research Hospital Ankara 06800 Turkey Faculty of Medicine Department of Cardiovascular Surgery Yddtrtm Beyaztt University Ankara 06800 Turkey

BackgroundTranscatheter 大动脉的阀门培植(TAVI ) 是在通过手术高的风险，或不能实行的病人的最低限度地侵略的、新兴的治疗。为风险分类使用的参数在病人的选择有一些缺乏。学习是在糖类抗原 125 上评估 TAVI 的影响的这的目的(CA125... 详细信息

BackgroundTranscatheter 大动脉的阀门培植(TAVI ) 是在通过手术高的风险，或不能实行的病人的最低限度地侵略的、新兴的治疗。为风险分类使用的参数在病人的选择有一些缺乏。学习是在糖类抗原 125 上评估 TAVI 的影响的这的目的(CA125 ) 和 N 终端职业人员大脑类型 Natriuretic 肽(NT-proBNP ) 作为在最近的年里经常被使用了的 biomarkers，并且也到 *** & 的这些 biomarkers 的关系；ResultsTranscatheter 大动脉的阀门培植在这研究在 31 个病人上被练习。然后，在病人学习在以前并且在 TAVI 以后的 CA125 和 NT-proBNP 层次被评估。病人也根据他们的左室的喷射部分(LVEF ) 被组织， CA125 铺平(LVEF ≥；40% 并且 <；40% ；CA125 ≤；35 U/L 和 >；35 U/L ) 。TAVI 手术成功地在所有病人被动。没有在里面医院死亡，在功能的能力的实质的改进在跟帖被检测。另外，统计上重要的减少在所有病人的 post-TAVI CA125 和 NT-proBNP 层次被检测(CA125 83.8 ±；18.1 U/L 对 64.3 ±；14.2 U/L， P = 0.008；NT-proBNP：4633.6 ±；627.6 pg/mL 对 2866.3 ±；536.8 pg/mL， P <；0.001 ) 。在根据 CA125 层次划分的组，也在 CA125 层次有统计上重要的 post-TAVI 衰落。在 CA125 > 以内；35 U/L 和 LVEF <；40% 组，对一个心律调整器的永久需要在(3.2%) 被要求病人和死亡在二被观察(6.4%) 在 TAVI 在以后的病人跟随 TAVI 能与 CA125 和 NT-proBNP 的高基线层次在病人有效地并且可靠地被执行的 *** 结果表演。当高 biomarker 层次与不希望得到的事件被联系时，这些 biomarkers 与 TAVI 实质地被减少，并且当然，这些 biomarkers 能为 TAVI 在耐心的选择被用于风险分类。

关键词：主动脉患者植入导管评价生物标志物水平划分 P值

Intraperitoneal dedifferentiated liposarcoma:A case report

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World Journal of Gastroenterology 2008年第38期14卷 5927-5929页

作者： Ali Karaman Mehmet esref Kabalar nder zcan Timur Koca Dogan Nasir Binici Department of Medical Genetics State HospitalErzurum 25240 Turkey Department of Pathology State HospitalErzurum 25240 Turkey Department of General Surgery State HospitalErzurum 25240 Turkey Department of Radiation Oncology State HospitalErzurum 25240 Turkey Department of Internal Medicine State HospitalErzurum 25240 Turkey

Dedifferentiated liposarcoma is a variant of liposarcoma with a more aggressive course. Mutations of the p53 gene have been found in different types of soft tissue sarcoma. It is generally accepted that p53 mutations in human malignant tumors are often related to a poor prognosis. In our case, analysis of p53 gene mutation in tumor samples was performed. p53 gene mutation was observed in dedifferentiated tumor tissue samples but not in well-differentiated tumor tissue samples. It has been reported that p53 gene mutation occurs most commonly in the retroperitoneum and rarely in other anatomic locations. Herein we report a case of dedifferentiated liposarcoma located at intraperitoneum.

关键词：腹膜内反分化脂肪肉瘤 p53基因基因突变基因治疗

Alteration of sister chromatid exchange frequencies in gastric cancer and chronic atrophic gastritis patients with and without H pylori infection

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World Journal of Gastroenterology 2008年第16期14卷 2534-2539页

作者： Ali Karaman Dogan Nasir Binici Mehmet esref Kabalar Hakan Dursun Ali Kurt Department of Medical Genetics State Hospital Department of Internal Medicine State Hospital Department of Pathology State Hospital Department of Gastroenterology State Hospital

AIM: To determine, by counting sister chromatid exchange (SCE) frequencies, whether genetic impairment and DNA damage have an effect on the pathogenesis of gastric cancer (GC). METHODS: Analysis of SCE is a cytogenetic technique used to show DNA damage as a result of an exchange of DNA fragments between sister chromatids. We analyzed SCE frequency in 24 patients with GC, 26 patients with chronic atrophic gastritis (CAG), and 15 normal controls. The presence of H pylori was confirmed by urease test, toluidine-blue stain and hematoxylin-eosin stain. RESULTS: SCE was significantly increased in H pylori- negative GC patients, and in H pylori-negative CAG patients compared with controls (7.41 ± 1.36 and 6.92 ± 1.20, respectively, vs 5.54 ± 0.8, P 0.05). On other hand, the SCE frequencies in H pylori-positive GC patients were higher than those in H pylori-positive CAG patients (9.20 ± 0.94 vs 7.93 ± 0.81, P < 0.01). Furthermore, H pylori-positive GC patients had a higher SCE frequency than H pylori- negative GC patients (9.20 ± 0.94 vs 7.41 ± 1.36, P < 0.001). Similarly, a significant difference was detected between H pylori-positive CAG patients and H pylori-negative CAG patients (7.93 ± 0.81 vs 6.92 ± 1.20, P < 0.05). CONCLUSION: We suggest the increased SCE in patients reflects a genomic instability that may be operative in gastric carcinogenesis.

关键词：胃癌慢性萎缩性胃炎发病机理幽门感染

Analysis of Triage Application in Emergency Department

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Open Journal of Emergency Medicine 2015年第3期3卷 13-17页

作者： Ali Kemal Erenler Inanc Ozel Yasemin Ece Mine Karabulut Aysun Orucoglu esref Ciftci Hitit University Corum Education and Research Hospital Department of Emergency MedicineCorumTurkey

Objectives: In this study, we aimed to determine the current status of Green Zone (GZ) application in our Emergency Department (ED). We also sought workload and economic burden of GZ on both healthcare providers and health system. Methods: We analyzed the medical data of patients admitted to the GZ of our ED in a three-year period. Demographical characteristics, complaints on admission, number of revisits and economical cost of the patients were determined. Results: During 3-year period a total of ~900,000 patients were admitted to Hitit University Corum Education and Research Hospital ED. Of these patients, 87,089 patients were treated in GZ. Upper respiratory system disease was the leading complaint on admission. Mean length of stay in ED for these patients was found to be 22.2 minutes. When repeated visits were investigated, it was found that 3029 patients presented twice to the GZ. Conclusion: Certain measures to reduce number of non-emergent patients presenting to ED must be taken immediately. Or else, dissatisfaction of both healthcare providers and patients shall remain as a potential cause of unwanted events in over-crowded EDs in the future.

关键词： Triage Overcrowding Green Zone Emergency Department

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某些农畜和实验动物饲料利用效率的遗传问题

中国畜牧兽医 1981年第6期 29-31+46页

作者：甘杰 esref Yüksel

家畜育种工作的主要目的之一是,发展那些比现有家畜能更有效地将饲料转变成肉品或其它产品的家畜品系。一般来说,大多数畜牧生产者为了改进饲料利用效率,在维持较低生产成本的同时,重点放在提高活体增重。 Biswas等(1966)指出“一头猪... 详细信息

家畜育种工作的主要目的之一是,发展那些比现有家畜能更有效地将饲料转变成肉品或其它产品的家畜品系。一般来说,大多数畜牧生产者为了改进饲料利用效率,在维持较低生产成本的同时,重点放在提高活体增重。 Biswas等(1966)指出“一头猪被养到上市重量,其成本的70—80％是饲料。猪群中各

关键词：饲料利用效率饲料消耗消耗量增重速度饲料利用率实验动物

Combination of allopurinol and hyperbaric oxygen therapy:A new treatment in experimental acute necrotizing pancreatitis?

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World Journal of Gastroenterology 2007年第46期13卷 6203-6207页

作者： Bilgin Comert Ahmet Turan Isik Sezai Aydin Ergun Bozoglu Bulent Unal Salih Deveci Nuket Mas esref Cinar Mehmet Refik Mas Division of Intensive Care Departments of Internal MedicineGulhane School of MedicineAnkara 06018Turkey Division of Geriatric Medicine Department of Internal MedicineGulhane School of MedicineAnkara 06018Turkey Department of Surgery Guven HospitalA.AyranciAnkara 06018Turkey Department of Surgery Numune Training HospitalSihhiyeAnkara 06018Turkey Department of Pathology Gulhane School of MedicineAnkara 06018Turkey Department of Anatomy Medical FacultyBaskent UniversityAnkara 06018Turkey Department of Infection Disease Gulhane School of MedicineAnkara 06018Turkey Department of Internal Medicine Gulhane School of MedicineAnkara 06018Turkey

瞄准：在试验性的老鼠在生物化学、组织病理学说的变化，氧化压力，和细菌的易位(BT ) 上调查 allopurinol 和高比重的氧(HBO ) 治疗的单个、联合的效果尖锐胰腺炎(AP ) 。方法：85 只 Sprague-Dawley 老鼠在学习被包括。85 只老鼠中的... 详细信息

瞄准：在试验性的老鼠在生物化学、组织病理学说的变化，氧化压力，和细菌的易位(BT ) 上调查 allopurinol 和高比重的氧(HBO ) 治疗的单个、联合的效果尖锐胰腺炎(AP ) 。方法：85 只 Sprague-Dawley 老鼠在学习被包括。85 只老鼠中的十五个被用作控制(假冒，组我) 。AP 在留下经由管内牛磺胆酸盐注入被导致七十只老鼠。幸存到尖锐引起坏死胰腺炎的正式就职的老鼠被使随机化进四个组。组 II 独自收到了 saline，组 III allopurinol，加 HBO 的组 IV allopurinol 和组 V HBO。浆液淀粉酶层次，氧化压力参数， BT 和组织病理学说的分数是坚定的。结果：浆液淀粉酶层次在与组 II 相比的组 III， IV 和 V 是更低的(974 +/- 110， 384 +/- 40， 851 +/- 56，和 1664 +/- 234 U/L，分别地 P < 0.05，为所有) 。联合揭示的二种处理选择显著地降低 median [25-75 百分位数] 组织病理学说的分数什么时候与单个政府相比(13 [12.5-15 ] 在 allopurinol 组， 9.5 [7-11.75 ] 在 HBO 组，并且 6 [4.5-7.5 ] 在联合的组， P < 0.01 ) 。氧化压力标记在与控制相比的所有处理组显著地更好。进胰和 mes 伤寒淋巴结的细菌的易位在与组 II 相比的组 III ， IV 和 V 是更低的(54%，23%，50%对为到胰的易位的100%，并且62%，46%，58%对为到 mes 伤寒淋巴节点的易位的100%，分别地 P < 0.05 为所有)。结论：当在试验性的老鼠 AP 独立管理了时，现在的学习证实 HBO 和 allopurinol 处理的利益。这些处理选择的联合看起来更有效地阻止胰腺的损害参数的前进。

关键词：胰腺炎别嘌呤醇高压氧法急性坏死