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The Evaluation of the Knee Joint in Terms of Magnetic Resonance Imaging Measurements in Osteoarthritis Patients:A Comparative Study Comprising a Control Group

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Open Journal of Radiology 2014年第1期4卷 111-119页

作者： Bozkurt Gulek Gokhan Soker ertugrul Erken Yakup Yesilkaya Behice Durgun Nazan Alpaslan Eda Soker Omer kaya Eren Erken Department of Radiology Namik Kemal UniversityTekirdagTurkey Department of Radiology Numune Teaching and Research HospitalAdanaTurkey Department of Nephrology Gaziosmanpasa UniversityTokatTurkey Department of Radiology Kirsehir State HospitalKirsehirTurkey Department of Anatomy Cukurova UniversityAdanaTurkey Department of Biostatistics Cukurova UniversityAdanaTurkey Department of Physical Therapy and Rehabilitaiton Numune Teaching and Research HospitalAdanaTurkey Department of Rheumatology and Immunology Cukurova UniversityAdanaTurkey

The aim of this study was to assess the knee joints of osteoarthritis patients in terms of clinical and magnetic resonance imaging (MRI) measurements and draw definitive conclusions from these quantimetric data. In order to achieve the above-mentioned goal, the knees of individuals from two distinct groups were examined by MRI. One group consisted of osteoarthritis patients while the other comprised the control individuals. All individuals from both groups underwent clinical and MRI measurements concerning their knees. These data were compared by using the statistical software from the Statistical Package for Social Sciences (SPSS) v.15 program. Statistically significant differences were found between the control and patients groups in terms of the measurements of the second (short) diameter of the medial femoral condyle, and the intercondylar distance (p < 0.05). In addition to these findings, the Receiver Operating Characteristics (ROC) curve analysis gave statistically significant results for both of these measurements. The cutoff values for these criteria were as follows in sequence order: a sensitivity of 75% and a specificity of 52% for the medial femoral condyle, and a sensitivity of 70% and a specificity of 70% for the intercondylar distance. The ROC curve data may not be a deterministic outcome alone for this study. But it may in fact have a significant meaning when it is evaluated together with other statistically significant data. The t-test for Equality of Means, for example, gave significant results, concerning the measurements of the short axis of the medial femoral condyle and the intercondylar distance. It is well known that it is the medial portion of the knee joint which deteriorates the most during the process of osteoarthritis of the knee (OAK), and this complies with the results of this study.

关键词： Osteoarthritis Knee MRI

Predictive value of C-reactive protein/albumin ratio in acute pancreatitis

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Hepatobiliary & Pancreatic Diseases International 2017年第4期16卷 424-430页

作者： Mustafa Kaplan Ihsan Ates Muhammed Yener Akpinar Mahmut Yuksel Ufuk Baris Kuzu Sabite Kacar Orhan Coskun ertugrul kayacetin Department of Gastroenterology Turkey Yuksek Ihtisas Training and Research HospitalAnkara 06100Turkey Department of Internal Medicine Ankara Numune Training and Research HospitalAnkara 06100Turkey

BACKGROUND:Serum C-reactive protein(CRP) increases and albumin decreases in patients with inflammation and ***,their role in patients with acute pancreatitis is not *** present study was to investigate the predictive significance of the CRP/albumin ratio for the prognosis and mortality in acute pancreatitis ***:This study was performed retrospectively with 192 acute pancreatitis patients between January 2002 and June *** scores,Atlanta classification and CRP/albumin ratios of the patients were ***:The CRP/albumin ratio was higher in deceased patients compared to *** CRP/albumin ratio was positively correlated with Ranson score and Atlanta classification in particular and with important prognostic markers such as hospitalization time,CRP and erythrocyte sedimentation *** addition to the CRP/albumin ratio,necrotizing pancreatitis type,moderately severe and severe Atlanta classification,and total Ranson score were independent risk factors of *** was found that an increase of 1 unit in the CRP/albumin ratio resulted in an increase of 1.52 times in mortality risk.A prediction value about CRP/albumin ratio >16.28 was found to be a significant marker in predicting mortality with 92.1% sensitivity and 58.0% *** was seen that Ranson and Atlanta classification were higher in patients with CRP/albumin ratio >16.28 compared with those with CRP/albumin ratio ≤*** with CRP/albumin ratio >16.28 had a 19.3 times higher chance of ***:The CRP/albumin ratio is a novel but promising,easy-to-measure,repeatable,non-invasive inflammationbased prognostic score in acute pancreatitis.

关键词： Atlanta classification C-reactive protein Glasgow prognostic score Ranson score acute pancreatitis

Reconfigurable intelligent surfaces for wireless communications:Overview of hardware designs,channel models,and estimation techniques

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Intelligent and Converged Networks 2022年第1期3卷 1-32页

作者： Mengnan Jian George C.Alexandropoulos ertugrul Basar Chongwen Huang Ruiqi Liu Yuanwei Liu Chau Yuen the Wireless Research Institute ZTE CorporationBeijing 100029China the State Key Laboratory of Mobile Network and Mobile Multimedia Technology Shenzhen 518055China Department of Informatics and Telecommunications National and Kapodistrian University of AthensAthens 15784Greece Communications Research and Innovation Laboratory(CoreLab) Department of Electrical and Electronics EngineeringKoçUniversityIstanbul 34450Turkey College of Information Science and Electronic Engineering Zhejiang UniversityHangzhou 310027China School of Electronic Engineering and Computer Science Queen Mary University of LondonLondonE14NSUK. the Engineering Product Development(EPD)Pillar Singapore University of Technology and DesignSingapore 487372Singapore

The demanding objectives for the future sixth generation(6G)of wireless communication networks have spurred recent research efforts on novel materials and radio-frequency front-end architectures for wireless connectivity,as well as revolutionary communication and computing *** the pioneering candidate technologies for 6G belong the reconfigurable intelligent surfaces(RISs),which are artificial planar structures with integrated electronic circuits that can be programmed to manipulate the incoming electromagnetic field in a wide variety of *** RISs in wireless networks have been recently advocated as a revolutionary means to transform any wireless signal propagation environment to a dynamically programmable one,intended for various networking objectives,such as coverage extension and capacity boosting,spatiotemporal focusing with benefits in energy efficiency and secrecy,and low electromagnetic field *** by the recent increasing interests in the field of RISs and the consequent pioneering concept of the RIS-enabled smart wireless environments,in this paper,we overview and taxonomize the latest advances in RIS hardware architectures as well as the most recent developments in the modeling of RIS unit elements and RIS-empowered wireless signal *** also present a thorough overview of the channel estimation approaches for RIS-empowered communications systems,which constitute a prerequisite step for the optimized incorporation of RISs in future wireless ***,we discuss the relevance of the RIS technology in the latest wireless communication standards,and highlight the current and future standardization activities for the RIS technology and the consequent RIS-empowered wireless networking approaches.

关键词： reconfigurable intelligent surfaces beyond 5G 6G channel modeling hardware architecture channel estimation smart wireless environment standardization

Alverine citrate induced acute hepatitis

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World Journal of Gastroenterology 2004年第15期10卷 2303-2304页

作者： Mehmet Arhan Seyfettin Kklü Aydln S Kksal mer F Yoicu Senem Koruk Irfan Koruk ertugrul kayacetin Kavaklik mah Ahmet Apaydln cadSultan ApartmentNo 39/7Sahinbey 27060GaziantepTurkey

Alverine dtrate is a commonly used smooth muscle relaxant agent.A MEDLINE search on January 2004 revealed only 1 report implicating the hepatotoxicity of this agent.A 34- year-old woman was investigated because of the finding of elevated liver function tests on biochemical *** etiologies of hepatitis were appropriately ruled out and elevated enzymes were ascribed to alverine citrate treatment. Although alverine citrate hepatotoxicity was related to an immune mechanism in the first case,several features such as absence of predictable dose-dependent toxicity of alverine citrate in a previous study and absence of hypersensitivity manifestations in our patient are suggestive of a metabolic type of idiosyncratic toxicity.

关键词： Acute Disease Adult Female Hepatitis, Toxic Humans Propylamines

Effects of hyperbaric oxygen and Pgg-glucan on ischemic colon anastomosis

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World Journal of Gastroenterology 2006年第9期12卷 1421-1425页

作者： Suna Guzel Oguzhan Sunamak Abdullah AS Varol Celik Mehmet Ferahman Muhammed MK Nuri ertugrul Gazioglu Pinar Atukeren Ozgur Mutlu Department of General Surgery Cerrahpasa Faculty of Medicine IstanbulTurkey Department of Biochemistry Cerrahpasa Faculty of Medicine IstanbulTurkey Department of Underwater and Hyperbaric Oxygen Istanbul Faculty of Medicine IstanbulTurkey

AIM： In colorectal surgery, anastomotic failure is still a problem in ischemia. Here, we analyzed the effects of hyperbaric oxygen and beta-glucan on colon anastomoses in ischemic condition. METHODS： Colonic resection and anastomosis in rectosigmoid region were done in forty Wistar-Albino rats of four groups of equal number. Colon mesentery was ligated to induce ischemia. The first group was the control group. The subjects of second group were treated with hyperbaric oxygen; the third group with glucan and the forth group were treated with both. At the forth day, rats were sacrificed, anastomotic segment was resected and burst pressures and hydroxyproline levels of anastomotic line were measured. RESULTS： The burst pressure difference of second and third groups from the control group were meaningful （P〈0.01）; the forth group differed significantly from the control （P〈0.001）. There was no difference between the treated groups on burst pressure level （P〉0.05）. The hydroxyproline levels in all treated groups were different from the control group significantly （P〈0.001）. Hydroxyproline levels in the forth group were higher than those of the second and the third groups （P〈 0.001）. There were no significant differences between the second and the fourth groups in burst pressure and hydroxyproline levels （P〉 0.05）. CONCLUSION： Hyperbaric oxygen and glucan improve healing in ischemic colon anastomoses by anti-microbic,immune stimulating properties and seem to act synergistically when combined together.

关键词： Anastomosis Ischemic colon Hyperbaric oxygen PGG-Glucan

Viral and host causes of fatty liver in chronic hepatitis B

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World Journal of Gastroenterology 2005年第20期11卷 3056-3059页

作者： Emin Altiparmak Seyfettin K(o|¨)klü Mesut Yalinkilic Osman Yüksel Bahattin Cicek ertugrul kayacetin Tülin Sahin Department of Gastroenterohepatology Yüksek Ihtisas Hospital Sihhiye Ankara Turkey

AIM: To investigate the viral and host causes of fatty liver in chronic hepatitis B patients and the role of fat deposits in liver ***: A total of 164 patients (113 males and 51 females, average age 35±11.3 years, and range 10-62 years) with previously untreated chronic hepatitis B were included in the study. The patients were divided into two groups depending on the result of liver biopsy: group without steatosis (100 patients with ＜5% hepatosteatosis) and group with steatosis (64 patients with ＞5% hepatosteatosis). The groups were compared in terms of gender, body mass index (BMI), liver enzymes (ALT, AST, ALP, GGT), cholesterol, triglyceride, HBeAg, viral load, and histological findings. In the group with steatosis, the patients were subdivided depending on the degree of steatosis into mild group (45 patients with 5-24% steatosis), and severe group (19 patients with ＞25% steatosis). RESULTS: In the group of chronic hepatitis B with steatosis, the mean age, BMI, cholesterol, and triglyceride levels were significantly higher than those in the group without steatosis (P＜0.05). Steatosis was found in 53 (46.9%) of male patients and 11 (22%) of female patients (P＜0.05). No significant difference was found in the positivity of ALT, AST, ALP, GGT, HBeAg, viral load, histological activity index (HAI) and stage between the two groups (P＞0.05). In the group with severe steatosis, the BMI was significantly higher than that in the group with mild steatosis (P＜0.05). No significant difference was found in the other parameters between the groups (P＞0.05). CONCLUSION: Steatosis in chronic hepatitis B appears to be a result of metabolic factors of the host rather than the effect of viruses. Steatosis is unrelated to the HAI and degree of fibrosis, which are considered as the histological indicators of liver damage.

关键词： Chronic hepatitis B Steatosis

Digoxin intoxication： An old enemy in modern era

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Journal of Geriatric Cardiology 2012年第3期9卷 237-242页

作者： Bahadir Kirilmaz Serkan Saygi Hasan Gungor Ugur Onsel Turk Emin Alioglu Serdar Akyuz Fatih Asgun Istemihan Tengiz ertugrul Ercan Department of Cardiology Canakkale Onsekiz Mart University Medical Faculty Canakkale 17100 Turkey Department of Cardiology Odemis State Hospital Izmir 35750 Turkey Department of Cardiology Central Hospital Izmir 35580 Turkey Department of Cardiology Yunus Emre State Hospital Eskisehir 26190 Turkey Department of Cardiovascular Surgery Canakkale Onsekiz Mart University Medical Faculty Canakkale 17100 Turkey

Objectives Although development of new treatment modalities limited digoxin usage, digoxin intoxication is still an important issue which could be easily overlooked. In this report, we analyzed a case series definitively diagnosed as digoxin intoxication in the modern era. Methods We analyzed 71 patients hospitalized with digoxin intoxication confirmed by history, complaints, clinical and electrocardiograph （ECG） findings, and serum digoxin levels 〉 2.0 ng/mL, during a five year period. The demographic and clinical data, indications for digoxin use, digoxin dosage, concurrent medications, laboratory data, hospital monitoring, and ECG findings were obtained from all patients. Results Thirty-eight of 71 patients （53.5%） had symptoms of heart failure during admission or later. Sixty-four percent of patients were older than 75 years. The percentage of females was 67%. Atrial fibrillation, hypertension and gastrointestinal complaints were more frequent in the females （64% in females, 30% in males, P = 0.007; 81% in female, 52% in males, P = 0.01; 50% in female, 17.3% in males, P = 0.008, respectively）. The mortality rate during the hospital course was 7%. Conclusions This report demonstrated the reduced mortality rates in patients with digoxin intoxication over the study period. Gastrointestinal complaints are the most common symptoms in this population.

关键词： Digoxin intoxication Digitalis Heart failure Arrhythmia

Effect of the COVID-19 pandemic on patients with presumed diagnosis of acute appendicitis

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World Journal of Clinical Cases 2022年第29期10卷 10487-10500页

作者： Sami Akbulut Adem Tuncer Zeki Ogut Tevfik Tolga Sahin Cemalettin Koc Emek Guldogan ertugrul Karabulut Elif Seren Tanriverdi Ali Ozer Surgery and Liver Transplant Institute Inonu University Faculty of MedicineMalatya 44280Turkey Department of Biostatistics and Medical Informatics Inonu University Faculty of MedicineMalatya 44280Turkey Department of Public Health Inonu University Faculty of MedicineMalatya 44280Turkey Department of Surgery Inonu University Faculty of MedicineMalatya 44280Turkey Department of Medical Microbiology Inonu University Medical FacultyMalatya 44280Turkey

BACKGROUND Acute appendicitis(AAp) is the most frequent cause of acute abdominal pain,and appendectomy is the most frequent emergency procedure that is performed *** coronavirus disease 2019(COVID-19) pandemic has caused delays in managing diseases requiring emergency approaches such as AAp and *** To compare the demographic,clinical,and histopathological outcomes of patients with AAp who underwent appendectomy during pre-COVID-19 and COVID-19 *** The demographic,clinical,biochemical,and histopathological parameters were evaluated and compared in patients who underwent appendectomy with the presumed diagnosis of AAp in the pre-COVID-19(October 2018-March 2020) and COVID-19(March 2020-July 2021) *** Admissions to our tertiary care hospital for AAp increased 44.8% in the COVID-19 ***-19(n = 154) and COVID-19(n = 223) periods were compared for various parameters,and we found that there were statistically significant differences in terms of variables such as procedures performed on the weekdays or weekends [odds ratio(OR):1.76;P = 0.018],presence of AAp findings on ultrasonography(OR:15.4;P < 0.001),confirmation of AAp in the histopathologic analysis(OR:2.6;P = 0.003),determination of perforation in the appendectomy specimen(OR:2.2;P = 0.004),the diameter of the appendix(P < 0.001),and hospital stay(P = 0.003).There was no statistically significant difference in terms of interval between the initiation of symptoms and admission to the hospital between the pre-COVID-19(median:24 h;interquartile range:34) and COVID-19(median:36 h;interquartile range:60) periods(P = 0.348).The interval between the initiation of symptoms until the hospital admission was significantly longer in patients with perforated AAp regardless of the COVID-19 or pre-COVID-19 status(P < 0.001).CONCLUSION The present study showed that in the COVID-19 period,the ultrasonographic determination rate of AAp,perforation rate of AAp,and duration of hospital

关键词： SARS-CoV-2 COVID-19 pandemic Acute appendicitis Perforated appendicitis Negative appendectomy

Structural,Optical and Electrochromic Properties of WO3 Thin Films Prepared by Chemical Spray Pyrolysis Versus Spin Coating Technique

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光谱学与光谱分析 2018年第9期38卷 2982-2988页

作者： S.Morkoc Karadeniz Demet Tatar M.ertugrul A.E.Ekinci Department of Physics Erzincan UniversityErzincan 24000Turkey Pasinler Vocational School Atatürk UniversityErzurum 25040Turkey Department of Electrical and Electronics Engineering Atatürk UniversityErzurum 25040Turkey

In this study,Tungsten Oxide(WO_3)thin films were prepared by Chemical Spray Pyrolysis(CSP)and Spin Coating(SC)techniques and it was investigated effects of technique and parameter on the ***_3 thin films were deposited on ITO(Indium Tin Oxide)coated *** structural,optical and electrochromic properties of the WO_3 thin films were characterized by XRD,SEM,UV,and CV *** sharpest(200)peak was observed in the XRD spectra and optical band gaps were calculated around 2.6～3.1 eVvia UV-Vis spectra for all of the *** fibrous reticulated surface(filamentous like)morphology for the films deposited by CSP technique and smooth surface morphology with high optical transmittance for the film deposited by SC Technique were obtained from SEM *** addition to these results,it was revealed that all the samples exhibit good electrochromic performance.

关键词： Spray pyrolysis Spin coating WO3