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A FAST,HIGH SENSITIVITY AND HIGH MASS ACCURACY API TIME-OF-FLIGHT MASS SPECTROMETER AND ITS APPLICATIONS

质谱学报 1999年第Z1期 11-12页

作者： SHEN Shida, erol Gulcicek, Bruce Andrien, Craig Whitehouse (Analytica of Branford inc., 29 Business Park Dr., Branford, Connecticut 06405, USA)

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Presence of Fragmented QRS Complexes in Patients with Obstructive Sleep Apnea Syndrome

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Chinese Medical Journal 2015年第16期128卷 2141-2146页

作者： Muhammet Rasit Sayin Murat Altuntas Ziyaeddin Aktop Ibrahim I Oz Nesimi Yavuz Ibrahim Akpinar erol Sagatli Turgut Karabag Mustafa Aydin Department of Cardiology School of MedicineBulent Ecevit UniversityZonguldakTurkey Department of Pulmonology Uzun Mehmet State HospitalZonguldakTurkey Department of Radiology School of MedicineBulent Ecevit UniversityZonguldakTurkey Department of Cardiology Ataturk State Hospital Zonguldak Turkey

Background：Obstructive sleep apnea syndrome （OSAS） is a disease with increasing prevalence,which is mainly characterized by increased cardiopulmonary mortality and *** is well-known that OSAS patients have increased prevalence of cardiovascular diseases including coronary heart disease,heart failure,and *** aim of this study was to evaluate the presence of prolonged and fragmented QRS complexes,which have previously been associated with cardiovascular mortality,in OSAS ***：Our study included 51 patients （mean age 41.6 ± 10.1 years） who were recently diagnosed with OSAS （apnea-hypopnea index [AHI] ≥5 events/h） and never received *** control group consisted of 34 volunteers （mean age 43.1 ± 11.6 years） in whom OSAS was excluded （AHI 〈5 events/h）.The longest QRS complexes was measured in the 12-lead electrocardiogram （ECG） and the presence of fragmentation in QRS complexes was ***：Fragmented QRS frequency was significantly higher in patients with OSAS （n =31 [61%] vs.n =12 [35%],P =0.021）.QRS and QTc durations were also significantly longer in OSAS patients than controls （99.8 ± 13.9 ms vs.84.7 ± 14.3 ms,P 〈 0.001;411.4 ± 26.9 ms vs.390.1 ± 32.2 ms,P =0.001,respectively）.Analysis of the patient and controls groups combined revealed a weak-moderate correlation between AHI and QRS duration （r =0.292,P =0.070）.OSAS group had no correlation between AHI and QRS duration （r =-0.231,P =0.203）.Conclusions：In our study fragmented QRS frequency and QRS duration were found to increase in OSAS *** parameters are related with increased cardiovascular *** the prognostic importance of ECG parameters,it may be reasonable to recommend more detailed evaluation of OSAS patients with fragmented or prolonged QRS complexes with respect to presence of cardiovascular diseases.

关键词： Electrocardiogram Fragmented QRS Obstructive Sleep Apnea QRS Duration QT Duration

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基于颗粒真实几何形状的铁路道砟剪切过程三维离散元分析

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工程力学 2015年第5期32卷 64-75,83页

作者：边学成李伟李公羽 erol Tutumluer 浙江大学岩土工程研究所浙江杭州310058 伊利诺伊香槟分校土木与环境工程系美国伊利诺伊州61801

铁路道床由尺寸和形状各异的道砟颗粒组成,道砟颗粒的形状对道床的强度、变形等力学特性具有显著影响,反映颗粒单一方向尺寸分布特征的级配曲线难以全面描述形状不规则的道砟颗粒的几何特征。该文利用计算机视觉成像技术获得道砟颗粒在... 详细信息

铁路道床由尺寸和形状各异的道砟颗粒组成,道砟颗粒的形状对道床的强度、变形等力学特性具有显著影响,反映颗粒单一方向尺寸分布特征的级配曲线难以全面描述形状不规则的道砟颗粒的几何特征。该文利用计算机视觉成像技术获得道砟颗粒在三个相互垂直方向的投影图,提取投影图轮廓并计算其几何特征参数;基于颗粒三视图重建与真实道砟颗粒具备相同几何特征的三维模型,引入到自行开发的三维块体离散元数值模拟程序中,建立了真实道砟颗粒料的三维离散元分析模型。通过与多种竖向压力作用下的室内直剪试验结果进行对比,验证了该方法可靠性;并在此基础上对道砟颗粒料在直剪试验中的变形和细观力学特性进行了深入详细的分析。

关键词：道砟计算机视觉技术几何特征离散元方法直剪试验

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Does Anti-Vascular Endothelial Growth Factor Treatment Delay Photoreceptor Maturation in Preterm Infants?

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Open Journal of Ophthalmology 2020年第1期10卷 10-20页

作者： Elcin Süren,Ersan Cetinkaya Mehmet Fatih Kücük Musatafa Kalayci Muhammet Kazim erol Antalya Training and Research Hospital Department of OphthalmologyAntalyaTurkey

Purpose: To investigate the effects of intravitreal anti-vascular endothelial growth factor (VEGF) for treatment of type-1 or aggressive posterior retinopathy of prematurity (ROP) on photoreceptor maturation in preterm infants using spectral domain optical coherence tomography (SD-OCT). Methods: A study group of 36 patients with ROP treated with anti-VEGF therapy was compared to a control group of 80 patients with ROP. All patients had undergone SD-OCT imaging at least once between 40 and 44 weeks post-menstrual age (PMA). Two imaging specialists evaluated the images for ellipsoid zone (EZ) development, cystoid macular edema (CME), sub-retinal fluid (SRF) at the fovea, and cone outer segment tips (COST). The outer nuclear layer thickness and the distance from the EZ to the central fovea was measured. Results: EZ development was observed in 18 (50%) patients in the study group and 68 (85%) in the control group (p = 0.002). CME was observed in 17 (47.2%) patients in the study group and 17 (21.2%) in the control group. The distance between the EZ and central fovea was 868 ± 440 μm in the study group and 725 ± 380 μm in the control group (p = 0.02). COST was not observed in any patient. Regression analysis indicated that anti-VEGF treatment and CME affect EZ development. Conclusions: Early photoreceptor maturation is correlated with preterm birth week but not ROP stage. Anti-VEGF treatment delays photoreceptor maturation in preterm infants.

关键词： Cystoid Macular Edema Photoreceptor Retinopathy of Prematurity Vascular Endothelial Growth Factor

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An Unusual Paraneoplastic Syndrome of Synchronous Bladder Tumor and Prostate Cancer: Polymyositis

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Open Journal of Urology 2015年第10期5卷 179-181页

作者： Huseyin Badem Mehmet erol Yildirim Serife Badem Ozlem Sahin Balcik Sedat Tastemur Ersin Cimentepe Urology Department Turkey Yuksekİhtisas HospitalAnkaraTurkey Urology Department Turgut Ozal Universty HospitalAnkaraTurkey Radiology Department Turkey Yuksekİhtisas HospitalAnkaraTurkey Haematology Department Turgut Ozal Universty HospitalAnkaraTurkey

Introduction: Polymyositis (PM) is a type of inflammatory myopathy that is associated with a broad range of malignant disorders. An association of PM with synchronous carcinoma of the bladder and prostate is extremely rare. Case: A 65-year-old man admitted to hematology with complaints of severe progressive weakness of lower extremities, hematuria and irritative urinary symptoms lasting for a month. The hemogram and erythrocyte sedimentation rate were normal. ALT was normal but AST was 405.56 U/l. There was marked elevation of serum creatine kinase (CK) and lactate dehydrogenase, which were 14,065.15 U/l and 1267.50 U/l, respectively. PSA was 4.28 and DRE was positive. The abdominal ultrasound revealed a 24 × 20 mm soft tissue echogenicity lesion at the right wall and a 35 × 21 mm soft tissue echogenicity lesion at the left wall of the bladder. The rest of the abdominal viscera were normal. Computed tomography found, two 6 mm solid lesions at left anterolateral and a 18 × 12 mm solid lesion at inferoanterior bladder wall in addition to the above findings. Patient counseled to us. We resected all of the bladder masses with transurethral (TUR-BT) way and pathology revealed T2 high grade bladder tumor. Two days after TUR-BT, we performed a trans rectal ultrasonography guided prostate biopsy and pathology revealed a Gleason 3 + 4 prostate cancer. EMG showed sensorimotor polyneuropathy at the lower extremities, sustaining polymyozitis. Biopsy of the right peroneus brevis muscle showed no vasculitis with low grade neurologic changes. We offered to perform a radical cystoprostatectomy operation but the patient prefered chemotherapy. Two months after his initial presentation at the second cure of the chemotherapy all muscle weaknesses showed a dramatic regression. Conclusion: This case report indicates that both bladder carcinoma and prostate cancer should be kept in mind in elderly PM patients presenting with lower urinary tract symptoms and hematuria.

关键词： Polymyositis Bladder Tumor Prostate Cancer Emg

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High pressure paint gun injury of the index finger:a case report

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Plastic and Aesthetic Research 2015年第1期2卷 350-352页

作者： Memet Yazar Zeliha Gül Ali Can Günenç Sevgi Kurt Yazar erol Kozanoğlu Plastic Reconstructive and Aesthetic Surgery ClinicSisli Etfal Training and Research Hospital34371 IstanbulTurkey Plastic Reconstructive and Aesthetic Surgery ClinicIstanbul Training and Research Hospital34098 IstanbulTurkey Plastic Reconstructive and Aesthetic Surgery ClinicIstanbul UniversityIstanbul Medicine Faculty34093 IstanbulTurkey

Injuries to the hand secondary to high pressure paint guns are considered to be true hand *** rare injuries may have serious outcomes,and a critical step in their management is extensive debridement performed within the first six hours following *** this reason,their diagnosis should not be delayed,and the hand surgeon should be informed immediately to initiate appropriate *** this report,the authors describe a patient who was injured with a chemical paint gun,and whose injury was not diagnosed in the emergency *** patient subsequently developed *** treatment is reported herein.

关键词： Finger injury high pressure injury trauma

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Three Consecutive Monthly Intravitreal Ranibizumab for Choroidal Neovascularization in Central Serous Choriorethinopathy:A Case Report

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Open Journal of Ophthalmology 2012年第3期2卷 93-96页

作者： Kazim erol Esin Sogutlu Sari Arif Koytak A.Karacor D.T.Coban M.Bulut Ophthalmology Department Antalya Training and Research HospitalAntalyaTurkey Ophthalmology Department Kartal Training and Research HospitalIstanbulTurkey Ophthalmology Department Bezmialem Vakif UniversityIstanbulTurkey

Purpose: The author report the result of three consecutive monthly intravitreal ranibizumab injection for choroidal neovascularization (CNV) after bevacizumab injection for chronic central serous rethinopathy (CSR). Methods: A 48 year old man with chronic CSR was treated with intravitreal single dose 2.5 mg bevacizumab. One year after CNV was occurred, and three consecutive monthly intravitreal ranibizumab injections were performed. Results: Four weeks later the first ranibizumab dose, best corrected visual acuity was improved 20/80 to 20/20 and remained stable within one year. Conclusion: Repeat intravitreal ranibizumab injection in CNV after bevacizumab injection for chronic CSR appeared to be an effective treatment option.

关键词： Central Serous Choriorethinopathy Choroidal Neovascularization Ranibizumab

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酒精性肝病的发病机制

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中华肝脏病杂志 2003年第11期11卷 690-691页

作者：厉有名浙江大学医学院附属第一医院杭州310003

1.肝脏酒精代谢产物损伤:(1)乙醛的化学性损害:机体摄入的酒精90%以上在肝脏代谢,经过乙醇脱氢、肝微粒体乙醇氧化酶系统和过氧化氢酶氧化成乙醛,乙醛可损害各种细胞器和酶的结构功能;又能刺激免疫系统,诱发免疫反应性肝损害;损害线粒... 详细信息

1.肝脏酒精代谢产物损伤:(1)乙醛的化学性损害:机体摄入的酒精90%以上在肝脏代谢,经过乙醇脱氢、肝微粒体乙醇氧化酶系统和过氧化氢酶氧化成乙醛,乙醛可损害各种细胞器和酶的结构功能;又能刺激免疫系统,诱发免疫反应性肝损害;损害线粒体脂肪酸的β氧化,引起脂质过氧化反应,抑制谷胱甘肽(GSH)的生物合成,减弱超过氧化物酶等抗氧化功能.

关键词：酒精性肝病发病机制线粒体损害氧应激脂质过氧化

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两侧有覆面板的木结构剪力墙侧向变形计算

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结构工程师 2007年第5期23卷 25-29,40页

作者：张盛东 Chun Ni erol Karacabeyli 同济大学建筑工程系上海200092 加拿大国家林产工业技术研究院木结构工程部

木材是与环境最和谐的一种建筑材料。木结构剪力墙是轻型木结构的主要竖向抗侧力构件,为了消防的需要,木结构剪力墙内侧常覆有防火石膏板,现在某些国家的木结构规范中已考虑石膏板对剪力墙承载力的有利影响。尽管有些国家的建筑规范中... 详细信息

木材是与环境最和谐的一种建筑材料。木结构剪力墙是轻型木结构的主要竖向抗侧力构件,为了消防的需要,木结构剪力墙内侧常覆有防火石膏板,现在某些国家的木结构规范中已考虑石膏板对剪力墙承载力的有利影响。尽管有些国家的建筑规范中已给出了估算单侧木基结构面板覆面木结构剪力墙侧向变形的方法,但并不适合于两侧有覆面板的木结构剪力墙。研究将美国《统一建筑规范》中的4项变形公式进行扩展来预测一侧为木基结构面板覆面、另一侧为石膏板覆面木结构剪力墙的变形,所得公式预测值与试验结果对比较好。

关键词：变形两侧覆面木结构剪力墙木基面板石膏板钉节点

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基于地震观测的钢框架结构有限元模拟与易损性分析

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防灾科技学院学报 2018年第4期20卷 16-22页

作者：王飞康现栋马洁美 Kalkan erol 北京市地震局北京100080 中国地震局地球物理研究所北京100081 美国地质调查局门罗帕克94025

基于性能的抗震设计需要揭示准确有效的地震动参数以满足结构易损性研究的要求。选择开展结构观测的6层钢结构作为分析实例,建立结构有限元模型。以Northridge地震中结构反应记录作为输入开展结构模态和动力反应分析。利用地震记录识别... 详细信息

基于性能的抗震设计需要揭示准确有效的地震动参数以满足结构易损性研究的要求。选择开展结构观测的6层钢结构作为分析实例,建立结构有限元模型。以Northridge地震中结构反应记录作为输入开展结构模态和动力反应分析。利用地震记录识别结构的自振特性和位移反应,将识别结果与分析结果进行对比,直至模型分析结果与识别结果吻合,完成有限元模型的标定。选择20条地震动开展结构增量动力分析,将基于PGA和Sa(T1)的顶层位移角分布曲线与Pushover分析曲线进行对比。分析表明Sa(T1)较PGA更适合开展该结构易损性研究。建立Sa(T1)和层间位移角的关系曲线,确定达到某一层间位移角水平的地震动数量,并以此作为计算概率密度函数的依据,构造出Probit概率密度模型,得到该结构达到不同破坏状态的易损性曲线。分析表明钢结构具有良好的抗震性能,适用于地震高风险区的建设工程。

关键词：地震观测有限元模拟增量动力分析地震动特性易损性曲线

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