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Papillary Muscle Function Does Not Predict Mitral Regurgitation in Patients with Normal Left ventricular Systolic Function: A Transesophageal Echocardiographic Study

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International Journal of Clinical Medicine 2011年第2期2卷 178-183页

作者： ernest C. Madu Dainia S. Baugh Edwin Tulloch-Reid Chiranjivi Potu 不详

Objective: To evaluate Lv papillary muscles (PM) function using transesophageal echocardiography (TEE), and to determine the relationship between PM function and mitral regurgitation in patients with normal left ventricular sys-tolic function. Design: TEE examinations were prospectively performed. End diastolic and end systolic PM lengths were obtained from the transgastric long axis views and fractional systolic shortening (FS) was calculated. Lv ejection fraction was determined using modified Simpson rule and mitral regurgitation was determined using regurgitant jet area by color flow. Setting: Tertiary Center. Patients: 85 consecutive adult patients (51 with mitral regurgitation and 34 without) with normal Lv chamber dimensions and Lv systolic function, meeting enrollment criteria. Results: The % FS in patients with mitral regurgitation was 21.7 ± 3.6% for anterior PM (APM) and 18.7 ± 4.6% for posterior PM (PPM). In those without mitral regurgitation, the values were as follows;22.6 ± 5.4% (APM) and 19.5 ± 3.8% (PPM). In a subgroup of patients with severe mitral regurgitation (n = 23), the values for PM FS were 20.3 ± 6.8 (APM) and 18.4 ± 6.9 % (PPM). There was no statistically significant difference in PM fractional shortening between the groups. Anterior papillary muscle length was longer in those patients with mitral regurgitation compared to those without [(End-diastolic length (cm): 3.38 ± 0.61 v 2.88 ± 0.47(p: 0.008) and end-systolic length of 2.46 ± 0.51 v 2.17 ± 0.33 (p: 0.04)]. These differences are more pronounced in those with severe mitral regurgitation (p: 0.002 and 0.004 for EDL and ESL respectively. Conclusion: In patients with normal LvEF, PM contraction is similar in those with and without MR. In patients with MR however, anterior PM length (ED & ES) is significantly increased. Our data suggests that in patients with normal LvEF, PM dysfunction appears to play no significant role in the causation of MR. Anterior papillary muscle length however, a

关键词： Mitral Regurgitation TEE Papillary Muscle Lv Function

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Cancer Chemoprevention 2005

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丛书名： Cancer Drug Discovery and Development

2005年

作者： Gary J. Kelloff ernest T. Hawk Caroline C. Sigman

ISBN: (数字)9781592597680

ISBN: (纸本)9781588290779

Leading researchers comprehensively describe the exciting methodologies that are accelerating progress in chemoprevention and review the state of clinical development of preventive agents in the major human cancer target organs. The authors provide sound guidelines for cancer chemopreventive drug development, detailing general strategies and methods for drug discovery, preclinical efficacy, characterization of precancers, safety evaluation of clinical cohorts, and clinical trial design. The emphasis is on documenting the characterization and application of reliable biomarkers during chemopreventive drug development. Highlights include an elegant approach to identifying chemopreventive agents in natural products, the development of preclinical models for evaluating potential chemopreventive agents, the genomics and proteomics of potential applications, and approaches for determining which populations will likely benefit from chemopreventive intervention. A companion volume, Promising Cancer Chemopreventive Agents, comprehensively surveys those agents that have promise, or have already been successfully used, to treat precancerous conditions or inhibit carcinogenesis

关键词： CancerChemoprevention.

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Genetic Relationship between Sweet Grain Sorghum and the Other Sorghum Types Cultivated in Burkina Faso Assessed with Nuclear Microsatellite Markers SSRs

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American Journal of Plant Sciences 2022年第6期13卷 872-883页

作者： Josiane Tiendrebéogo Nerbéwendé Sawadogo Mariam Kiébré Zakaria Kiébré Sévérin Tuina Tégawendé Alphonse Sawadogo Kiswendsida Romaric Nanema Renan ernest Traoré Mahamadi Hamed Ouédraogo Mahamadou Sawadogo équipe Génétique et Amélioration des Plantes Laboratoire Biosciences Université Joseph KI-ZERBO Ouagadougou Burkina Faso

In Burkina Faso, sweet grain sorghum [Sorghum bicolor (L.) Moench] is generally cultivated in association with several other types of sorghum. However, the lack of information on the genetic relationship between this sorghum and grain sorghum as well as sweet stalk sorghum hinders the efficient management of its genetic resources. Thus, 34 sorghum accessions consisting of 14-grain sorghum, 10-sweet stalk sorghum, and 10 sweet grain sorghum were evaluated using 15 nuclear microsatellites markers (SSRs) to determine their genetic relationship. Results revealed significant genetic diversity within each sorghum type and a significant index of genetic differentiation per pair of sorghum types (0.017) between sweet grain sorghum and sweet stalk sorghum. The minimum Nei distance was also high (0.12) between these two sorghum types. Sweet grain sorghum indeed showed the lowest values of theoretical heterozygosity (0.35), of observed heterozygosity (0.13). Structuring of the accessions of the three types of sorghum cultivated in two distinct groups, one of grain sorghum and sweet stalk sorghum and another consisting of accessions of grain sorghum and sweet grain sorghum was also obtained. The low differentiation observed would suggest greater genetic proximity between the three types of sorghum. The differences observed would be more of a physiological and biochemical nature. These results could contribute to better management of the genetic resources of sweet grain sorghum.

关键词： Sorghum Markers Genetic Diversity Phylogeny Burkina Faso

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Anti-arthritic effect of Distemonanthus benthamianus extracts against rheumatoid arthritis in rats

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Asian Pacific Journal of Tropical Biomedicine 2022年第10期12卷 411-420页

作者： William Yousseu Nana ernest Allah Hoki Kwenteh Gilbert Ateufack Eric Gonzal Tsafack Stephanie FloreDjuichou Nguemnang Zenab Linda Fagni Njoya Albert Donatien Atsamo vanessa Mba Matah Marthe CarineFlore Adjouzem Yacine Karelle Madjo Kouam Elvira Ngoufack Azanze Marius Mbiantcha Laboratory of Biology and Physiology of Animal Organisms Department of Biology of Animal OrganismsFaculty of ScienceThe University of Douala CameroonP.O.Box 24157DoualaCameroon Research Unit of Animal Physiology and Phytopharmacology Faculty of ScienceUniversity of DschangDschangCameroon Laboratory of Animal Physiology Faculty of ScienceUniversity of Yaounde IYaoundéCameroon

Objective:To evaluate the anti-arthritic effect of aqueous and methanolic extracts of Distemonanthus ***:Monoarthritis was induced by an injection of 0.3 mL zymosan A(0.9%NaCl,v/v)in the right posterior knee joints of ***,joint diameter and pain threshold were *** was induced by an intracaudal injection of complete Freund’s adjuvant and rats were treated from day 14 post 1st complete Freund’s adjuvant injection until 28 *** clinical,hematological,biochemical and oxidative stress parameters were *** addition,histological analysis of the knee joint was perfomed in both ***:The aqueous and methanolic extracts of Distemonanthus benthamianus at a dose of 500 mg/kg ameliorated zymosan A-induced monoarthritis,as evidenced by reduced joint diameter,increased pain threshold,as well as improved joint *** addition,both extracts of Distemonanthus benthamianus markedly increased body weight and pain threshold,while reducing paw edema in polyarthritic *** also led to a marked decrease in platelets and white blood cells(Pvities,while increasing serum protein levels(Pvariation in creatinine ***,both extracts increased catalase and glutathione activities(Pver and *** analysis of the joints showed that both extracts triggered tissue ***:Distemonanthus benthamianus could be used as a potential candidate in the treatment of rheumatoid arthritis.

关键词： Distemonanthus benthamianus Rheumatoid arthritis Anti-arthritis Complete Freund’s adjuvant Hyperalgesia Inflammation Oxidative stress

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Metal organic framework‐ionic liquid hybrid catalysts for the selective electrochemical reduction of CO_(2) to CH4

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Chinese Journal of Catalysis 2022年第7期43卷 1687-1696页

作者： ernest Pahuyo Delmo Yian Wang Jing Wang Shangqian Zhu Tiehuai Li Xueping Qin Yibo Tian Qinglan Zhao Juhee Jang Yinuo Wang Meng Gu Lili Zhang Minhua Shao Department of Chemical and Biological Engineering The Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina Department of Materials Science and Engineering Southern University of Science and TechnologyShenzhen 518055GuangdongChina Jiangsu Key Laboratory for Chemistry of Low‐Dimension Materials Huaiyin Normal UniversityHuaian 223300JiangsuChina Energy Institute and Chinese National Engineering Research Center for Control&Treatment of Heavy Metal PollutionThe Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina

The electrochemical reduction of CO_(2) towards hydrocarbons is a promising technology that can utilize CO_(2) and prevent its atmospheric accumulation while simultaneously storing renewable en‐***,current CO_(2) electrolyzers remain impractical on a large scale due to the low current densities and faradaic efficiencies(FE)on various *** this study,hybrid HKUST‐1 metal‐organic framework‒fluorinated imidazolium‐based room temperature ionic liquid(RTIL)electrocatalysts are designed to selectively reduce CO_(2) to CH_(4).An impressive FE of 65.5%towards CH_(4) at-1.13 v is achieved for the HKUST‐1/[BMIM][PF_(6)]hybrid,with a stable FE greater than 50%maintained for at least 9 h in an H‐*** observed improvements are attributed to the increased local CO_(2) concentration and the improved CO_(2)‐to‐CH_(4) thermodynamics in the presence of the RTIL molecules adsorbed on the HKUST‐1‐derived Cu *** findings offer a novel approach of immobilizing RTIL co‐catalysts within porous frameworks for CO_(2) electroreduction applications.

关键词： CO_(2)electroreduction Methane Room temperature ionic liquid Metal organic framework Catalyst design DFT calculation

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军用寇明斯v—903柴油机提高到1000马力

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车用发动机 1984年第6期 1-17页

作者： Larry D.Fox,John W.Black,Pierre French,ernest E.Schwarz,张玉花寇明斯发动机公司寇明斯发动机公司霍尔塞特工程公司美国陆军坦克机动车辆局动力处

为了军用,寇明斯公司将一种普通的商用卡车发动机的额定功率从350马力提高到1000马力。采取的设计方法是提高发动机转速、降低压缩比、提高增压压力、中冷以及涡轮复合。本文详细介绍了性能分析、发动机的改进型和所需要的新涡轮机械... 详细信息

为了军用,寇明斯公司将一种普通的商用卡车发动机的额定功率从350马力提高到1000马力。采取的设计方法是提高发动机转速、降低压缩比、提高增压压力、中冷以及涡轮复合。本文详细介绍了性能分析、发动机的改进型和所需要的新涡轮机械的设计与发展。并且也介绍了发动机试验工作的结果。

关键词：马力高压比额定功率动力涡轮涡轮增压器发动机

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Bacteriological and Physicochemical Quality of Groundwater of Mbankomo Municipality(Center Region,Cameroon)

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Journal of Environmental Science and Engineering(B) 2023年第3期12卷 115-127页

作者： Murielle Patricia Mabou Tokam Antoine Tamsa Arfao Fils Mamert Onana ernest Koji vanelle Lontchi Segnou Yves Poutoum Yogne Awawou Manouore Njoya Ornel Kadji Tchantcha Ahmadou Fadimatou Sylvie Chinche Belengfe Edith Brunelle Mouafo Tamnou Moïse Nola Department of Animal Biology and Physiology Faculty of ScienceUniversity of DoualaDouala 24157Cameroon Hydrobiology and Environment Laboratory University of Yaounde 1Faculty of SciencesYaounde 812Cameroon Laboratoire d’Application et d’Analyses Médicales Institut Supérieur des Sciences et Techniques de la Santéet du Management de GarouaBP.51 GarouaCameroun Department of Aquatic Ecosystems Management Institute of Fisheries and Aquatic SciencesUniversity of DoualaDoualaCameroon Laboratory S3MN2E Faculty of SciencesMohammed-V University RabatAv.Ibn-BattoutaRabatMorocco 8007.N.U.North Africa Department of Fisheries and Aquatic Resources Management Faculty of Agriculture and Veterinary MedicineUniversity of BueaBuéa 63Cameroon

A study to evaluate the physico-chemical and bacteriological quality of groundwater was carried out in the commune of Mbankomo(Centre-Cameroon)at 4 wells and 4 springs during the period from March to *** physico-chemical parameters were measured by the standard *** bacteria of fecal contamination,namely HAB(Heterotrophic Aerobic Bacteria),total and faecal coliforms(Escherichia coli),and faecal streptococci were isolated by the surface spreading technique on PCA(Plate Count Agar),Endo and BEA(Bile Esculin Azide)agar respectively,and sulphite-reducing clostridia by the incorporation method on Tryptone Sulfite Cycloserine(TSC)*** a physico-chemical point of view,the groundwater in Mbamkomo is characterized by an average temperature(24.24±0.24°C);it is polluted with organic matter,acid and poorly *** was noted from a bacteriological point of view that these waters have a high and varied bacterial load with an average value of 100.8 × 10^(5) CFU/100 mL for coliforms,16.3 × 10^(5) CFU/100 mL for fecal streptococci,5.6 × 10^(5) CFU/100 mL for Escherichia coli and 4.8 ×10^(²)CFU/100 mL for Clostridium *** concentrations are all higher than the WHO(World Health Organization)standards which are set at 0 CFU/100 mL for coliforms,fecal streptococci and Clostridium perfringens and indicate fecal pollution of these *** coli cell densities were significantly correlated with dissolved oxygen in the water(r=0.510;pvored by their proximity to pollution sources,poor maintenance and poor protection of the *** waters,without any treatment,are not recommended for human consumption according to the standards of the WHO.

关键词： Groundwater physico-chemical quality bacteriological quality.

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Bioelectrochemically-assisted degradation of chloroform by a co-culture of Dehalobacter and Dehalobacterium

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"Environmental Science and Ecotechnology" 2022年第04期 41-46页

作者： David Fernández-verdejo Pilar Cortés Albert Guisasola Paqui Blánquez ernest Marco-Urrea Biorem UAB Department of Chemical Biological and Environmental Engineering School of Engineering Universitat Autònoma de Barcelona Departament de Genètica i de Microbiologia Facultat de BioCiències Universitat Autònoma de Barcelona GENOCOv Department of Chemical Biological and Environmental Engineering School of Engineering Universitat Autònoma de Barcelona

Using bioelectrochemical systems(BESs) to provide electrochemically generated hydrogen is a promising technology to provide electron donors for reductive dechlorination by organohalide-respiring bacteria. In this study, we inoculated two syntrophic dechlorinating cultures containing Dehalobacter and Dehalobacterium to sequentially transform chloroform(CF) to acetate in a BES using a graphite fiber brush as the electrode. In this co-culture, Dehalobacter transformed CF to stoichiometric amounts of dichloromethane(DCM) via organohalide respiration, whereas the Dehalobacterium-containing culture converted DCM to acetate via fermentation. BES were initially inoculated with Dehalobacter, and sequential cathodic potentials of-0.6,-0.7, and-0.8 v were poised after consuming three CF doses(500 μM) per each potential during a time-span of 83 days. At the end of this period, the accumulated DCM was degraded in the following seven days after the inoculation of Dehalobacterium. At this point, four consecutive amendments of CF at increasing concentrations of 200, 400, 600, and 800 μM were sequentially transformed by the combined degradation activity of Dehalobacter and Dehalobacterium. The Dehalobacter 16S r RNA gene copies increased four orders of magnitude during the whole period. The coulombic efficiencies associated with the degradation of CF reached values > 60% at a cathodic potential of-0.8 v when the degradation rate of CF achieved the highest values. This study shows the advantages of combining syntrophic bacteria to fully detoxify chlorinated compounds in BESs and further expands the use of this technology for treating water bodies impacted with pollutants.

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通过13N-NH3 PET检测冠脉血流储备和相对血流储备以诊断冠心病

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中华核医学与分子影像杂志 2017年第10期37卷 672-672页

作者：顾佳唐军苏州大学医学部放射医学与防护学院 215123 苏州大学附属第二医院核医学科 215004

目的使用13N-NH，PET显像检测冠脉血流储备（CFR）和相对血流储备（RFR），分析两者之间的关系以诊断冠心病。方法69例稳定性心绞痛患者在2周内接受13N—NH，PET显像和cT冠脉造影（CTA），必要时还行介入冠脉造影（CAG）。通过13N-NH，... 详细信息

目的使用13N-NH，PET显像检测冠脉血流储备（CFR）和相对血流储备（RFR），分析两者之间的关系以诊断冠心病。方法69例稳定性心绞痛患者在2周内接受13N—NH，PET显像和cT冠脉造影（CTA），必要时还行介入冠脉造影（CAG）。通过13N-NH，PET显像检测心肌血流（MBF）、CFR、RFR和相关冠脉供血区域的冠脉血管阻力（CvRref）。采用CTA和CAG评价冠脉明显狭窄（SS）和弥漫性动脉粥样硬化（DA）。比较有和无SS和DA的各冠状动脉的PET检测功能参数。结果有SS和DA的冠状动脉其负荷态MBF显著降低，有SS的冠脉其RFR显著降低，而CFR没有降低。有DA的冠脉其CFR显著降低，而RFR没有降低。在没有SS的冠脉中，有DA的其CFR显著降低，但在有SS的冠脉中，无论有无DA，CFR都相近。相反，无论有无DA，存在SS的冠脉其RFR显著降低。CFR和RFR在24例中（35％）呈不一致的弱正相关性（r=0．269）。在CFR和RFR不一致的冠脉中，CFR降低而RFR正常的冠脉其DA的发生率高于CFR正常而RFR降低的冠脉（75％比25％，P=0．028）。有DA的冠脉其CvR。显著升高，表明DA与潜在的微血管病变具有相关性。结论心肌血流灌注PET显像测定CFR和RFR为诊断CAD提供了更丰富的信息。

关键词：冠心病正电子发射断层显像术冠脉血流储备相对血流储备

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Performance of LHAASO-WCDA and observation of the Crab Nebula as a standard candle

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Chinese Physics C 2021年第8期45卷 166-181页

作者： F.Aharonian Q.An Axikegu L.X.Bai Y.X.Bai Y.W.Bao D.Bastieri X.J.Bi Y.J.Bi H.Cai J.T.Cai Z.Cao Z.Cao J.Chang J.F.Chang X.C.Chang B.M.Chen J.Chen L.Chen L.Chen L.Chen M.J.Chen M.L.Chen Q.H.Chen S.H.Chen S.Z.Chen T.L.Chen X.L.Chen Y.Chen N.Cheng Y.D.Cheng S.W.Cui X.H.Cui Y.D.Cui B.Z.Dai H.L.Dai Z.G.Dai Danzengluobu D.della volpe B.D'Ettorre Piazzoli X.J.Dong J.H.Fan Y.Z.Fan Z.X.Fan J.Fang K.Fang C.F.Feng L.Feng S.H.Feng Y.L.Feng B.Gao C.D.Gao Q.Gao W.Gao M.M.Ge L.S.Geng G.H.Gong Q.B.Gou M.H.Gu J.G.Guo X.L.Guo Y.Q.Guo Y.Y.Guo Y.A.Han H.H.He H.N.He J.C.He S.L.He X.B.He Y.He M.Heller Y.K.Hor C.Hou X.Hou H.B.Hu S.Hu S.C.Hu X.J.Hu D.H.Huang Q.L.Huang W.H.Huang X.T.Huang Z.C.Huang F.Ji X.L.Ji H.Y.Jia K.Jiang Z.J.Jiang C.Jin D.Kuleshov K.Levochkin B.B.Li C.Li C.Li F.Li H.B.Li H.C.Li H.Y.Li J.Li K.Li W.L.Li X.Li X.Li X.R.Li Y.Li Y.Z.Li Z.Li Z.Li E.W.Liang Y.F.Liang S.J.Lin B.Liu C.Liu D.Liu H.Liu H.D.Liu J.Liu J.L.Liu J.S.Liu J.Y.Liu M.Y.Liu R.Y.Liu S.M.Liu W.Liu Y.N.Liu Z.X.Liu W.J.Long R.Lu H.K.Lv B.Q.Ma L.L.Ma X.H.Ma J.R.Mao A.Masood W.Mitthumsiri T.Montaruli Y.C.Nan B.Y.Pang P.Pattarakijwanich Z.Y.Pei M.Y.Qi B.Q.Qiao D.Ruffolo v.Rulev A.Saiz L.Shao O.Shchegolev X.D.Sheng J.R.Shi H.C.Song Yu.v.Stenkin v.Stepanov Q.N.Sun X.N.Sun Z.B.Sun P.H.T.Tam Z.B.Tang W.W.Tian B.D.Wang C.Wang H.Wang H.G.Wang J.C.Wang J.S.Wang L.P.Wang L.Y.Wang R.N.Wang W.Wang W.Wang X.G.Wang X.J.Wang X.Y.Wang Y.D.Wang Y.J.Wang Y.P.Wang Z.Wang Z.Wang Z.H.Wang Z.X.Wang D.M.Wei J.J.Wei Y.J.Wei T.Wen C.Y.Wu H.R.Wu S.Wu W.X.Wu X.F.Wu S.Q.Xi J.Xia J.J.Xia G.M.Xiang G.Xiao H.B.Xiao G.G.Xin Y.L.Xin Y.Xing D.L.Xu R.X.Xu L.Xue D.H.Yan C.W.Yang F.F.Yang J.Y.Yang L.L.Yang M.J.Yang R.Z.Yang S.B.Yang Y.H.Yao Z.G.Yao Y.M.Ye L.Q.Yin N.Yin X.H.You Z.Y.You Y.H.Yu Q.Yuan H.D.Zeng T.X.Zeng W.Zeng Z.K.Zeng M.Zha X.X.Zhai B.B.Zhang H.M.Zhang H.Y.Zhang J.L.Zhang J.W.Zhang L.Zhang L.Zhang L.X.Zhang P.F.Zhang P.P.Zhang R.Zhang S.R.Zhang S.S.Zhang X.Zhang X.P.Zhang Y.Zhang Y.Zhang Y.F.Zhang Y.L.Zhang B.Zhao J.Zhao L.Zhao L.Z.Zhao S.P.Zhao F.Zheng Y.Zheng B.Zhou H.Zhou J.N.Zhou Key Laboratory of Particle Astrophyics&Experimental Physics Division&Computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China TIANFU Cosmic Ray Research Center ChengduSichuanChina State Key Laboratory of Particle Detection and Electronics China University of Science and Technology of China Hefei 230026China Department of Engineering Physics Tsinghua UniversityBeijing 100084China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China National Space Science Center Chinese Academy of SciencesBeijing 100190China School of Physics Peking UniversityBeijing 100871China Center for Astrophysics Guangzhou UniversityGuangzhou 510006China School of Physics and Astronomy&School of Physics(Guangzhou) Sun Yat-sen UniversityZhuhai 519082China School of Physical Science and Technology Guangxi UniversityNanning 530004China Hebei Normal University Shijiazhuang 050024China School of Physics and Microelectronics Zhengzhou UniversityZhengzhou 450001China School of Astronomy and Space Science Nanjing UniversityNanjing 210023China Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237China Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China Tsung-Dao Lee Institute&School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China School of Physical Science and Technology&School of Information Science and Technology Southwest Jiaotong UniversityChengdu 610031China College of Physics Sichuan UniversityChengdu 610065China Key Laboratory of Cosmic Rays(Tibet University) Ministry of EducationLhasa 850000China School of Physics and Technology Wuhan UniversityWuhan 430072China School of Physics and Astronomy Yunnan University

The first Water Cherenkov detector of the LHAASO experiment(WCDA-1)has been operating since April *** data for the first year have been analyzed to test its performance by observing the Crab Nebula as a standard *** WCDA-1 achieves a sensitivity of 65 mCU per year,with a statistical threshold of 5 *** accomplish this,a 97.7%cosmic-ray background rejection rate around 1 Tev and 99.8%around 6 Tev with an ap proximate photon acceptance of 50%is achieved after applying an algorithm to separate gamma-induced *** angular resolution is measured using the Crab Nebula as a point source to be approximately 0.45°at 1 Tev and better than 0.2°above 6 Tev,with a pointing accuracy better than 0.05°.These values all match the design *** energy resolution is found to be 33%for gamma rays around 6 *** spectral energy distribution of the Crab Nebula in the range from 500 Gev to 15.8 Tev is measured and found to be in agreement with the results from other Tev gamma ray observatories.

关键词： LHAASO-WCDA Crab Nebula angular resolution spectral energy distribution

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