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Venopulmonary ECMO Improved Hypoxemia and Supported the Right Ventricle in a Patient with Decompensated Eisenmenger Syndrome

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World Journal of Cardiovascular Surgery 2024年第1期14卷 7-19页

作者： Daniel Manzur-Sandoval Gian Manuel Jiménez-Rodríguez Edgar García-Cruz Ramón Espinosa-Soto erika Yamali Ramirez-Marcano Yessenia Máyory Téllez-lópez José luis Elizalde-Silva Gustavo Rojas-Velasco Cardiovascular Critical Care Unit Ignacio Ch&#225vez National Institute of Cardiology Mexico City Mexico Adult Congenital Heart Disease Unit Ignacio Ch&#225vez National Institute of Cardiology Mexico City Mexico Cardiology Department Ignacio Ch&#225vez National Institute of Cardiology Mexico City Mexico

Mechanical circulatory and/or respiratory assistance with extracorporeal membrane oxygenation (ECMO) has become a standard of care for patients with circulatory (venoarterial) and/or respiratory (venovenous) failure refractory to standard therapies. Adult patients with congenital heart disease are an increasingly recognized and growing population and include various groups, such as undiagnosed cases in childhood and palliated and/or corrected cases, which require subsequent care because of residual lesions, cardiac arrest/insufficiency, and arrhythmias, among other conditions. In addition, these patients are prone to developing pathologies that are typical of adulthood with a generally increased risk of morbidity and mortality because of their low reserves and organic damage associated with the underlying heart disease, which makes them candidates for ECMO. These patients represent an additional challenge in this therapy because malformations and the presence of a shunt can generally affect the usual cannulation methods and hemodynamic and oximetry monitoring. Thus, the configuration decision must be made on a case-by-case basis. Here, we present a cannulation method, venopulmonary artery ECMO, which provides hemodynamic and respiratory support, and may be ideal for patients with shunts and/or right ventricular dysfunction. To our knowledge, this is the first report of this configuration in patients with congenital heart diseases.

关键词： Eisenmenger Syndrome Venopulmonary Artery ECMO Refractory Hypoxemia Right Ventricular Dysfunction

eUREkA! T cells answer nature’s call

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Cellular & Molecular Immunology 2023年第7期20卷 692-693页

作者： Beth Kelly erika.l.Pearce Bloomberg-Kimmel Institute of Immunotherapy Department of OncologyJohns Hopkins University School of MedicineBaltimoreMDUSA

Nitrogen is critical for cell growth, proliferation, and function. Amino acid (AA) catabolism is a major source of intracellular nitrogen for biosynthesis but also generates the nitrogen-containing molecule ammonia (NH3+), which can accumulate to toxic levels in a cell if not exported to the circulation and detoxified by the urea cycle in the liver. In a recent paper in Nature Immunology, Tang et al. [1] discovered a functional urea cycle in memory T cells, which metabolizes ammonia, prevents its toxic accumulation.

关键词： function. ammonia cycle

Source identification and global implications of black carbon

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Geoscience Frontiers 2022年第1期13卷 404-416页

作者： erika P.Blanco-Donado Ismael l.Schneider Paulo Artaxo Jesus lozano-Osorio luana Portz Marcos l.S.Oliveira Department of Civil and Environmental Universidad de la CostaCUCBarranquilla080002Colombia Department of Applied Physics Institute of PhysicsUniversity of São PauloSP 05508-220Brazil Universidad de lima Avenida Javier Prado Este 4600Santiago de Surco 1503Peru

Black carbon(BC)is one of the short-lived air pollutants that contributes significantly to aerosol radiative forcing and global climate *** is emitted by the incomplete combustion of fossil fuels,biofuels,and *** environments are quite complex and thus,the use of mobile jointly with fixed monitoring provides a better understanding of the dynamics of BC distribution in such *** present study addresses the measurement of BC concentration using real-time mobile and ambient monitoring in Barranquilla,an industrialized urban area of the Colombian Caribbean.A microaethalometer(MA200)and an aethalometer(AE33)were used for measuring the BC *** absorption Ångström exponent(AAE)values were determined for the study area,for identifying the BC emission *** results of the ambient sampling show that vehicle traffic emissions prevail;however,the influence of biomass burning was also *** mean ambient BC concentration was found to be 1.04±1.03μg/m^(3) and varied between 0.5 and 4.0μg/m^(3).From the mobile measurements obtained in real traffic conditions on the road,a much higher average value of 16.1±16.5μg/m^(3) was *** parts of the city showed BC concentrations higher than 20μg/m^(3).The spatial distribution of BC concentration shows that vehicle emissions and traffic jams,a consequence of road and transport infrastructure,are the factors that most affect the BC concentration.A comparison of results obtained from two aethalometers indicates that the concentrations measured by MA200 are 9%lower than those measured by *** AAE obtained was found to vary between 1.1 and 1.6,indicating vehicular emissions as the most crucial *** addition,it was observed that the BC concentration on working days was 2.5 times higher than on the weekends in the case of mobile monitoring and 1.5 times higher in the case of ambient monitoring.

关键词： Air pollution Black carbon Spatial distribution Source apportionment AbsorptionÅngström exponent

Advantageous mechanochemical synthesis of copper(Ⅰ)selenide semiconductor,characterization,and properties

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Frontiers of Chemical Science and Engineering 2022年第3期16卷 433-442页

作者： Katarína Gáborová Marcela Achimovičová Michal Hegedüs Vladimír Girman Mária Kaňuchová erika Dutková Institute of Geotechnics Slovak Academy of SciencesKošice04001Slovakia Institute of Metallurgy Faculty of MaterialsMetallurgy and RecyclingTechnical UniversityKošice04201Slovakia Synthon s.r.o.Blansko67801Czech Republic Faculty of Science Pavol JozefŠafárik UniversityKošice04154Slovakia Institute of Earth Resources Faculty of MiningEcologyProcess Control and GeotechnologiesTechnical UniversityKošice04200Slovakia

Copper(I)selenide-nanocrystalline semiconductor was synthesized via one-step mechanochemical synthesis after 5 min milling in a planetary ball *** kinetics of synthesis was followed by X-ray powder diffraction analysis and specific surface area measurements of milled 2Cu/Se *** X-ray diffraction confirmed the orthorhombic crystal structure of Cu_(2)Se with the crystallite size∼25 *** surface chemical structure was studied by X-ray photoelectron spectroscopy,whereby the binding energy of the Cu 2p and Se 3d signals corresponded to Cu^(+)and Se^(2−)oxidation *** electron microscopy revealed agglomerated nanocrystals and confirmed their orthorhombic structure,as *** optical properties were studied utilizing ultraviolet-visible spectroscopy and photoluminescence *** direct bandgap energy 3.7 eV indicated a blue-shift phenomenon due to the quantum size *** type of Cu_(2)Se synthesis can be easily adapted to production dimensions using an industrial vibratory *** advantages of mechanochemical synthesis represent the potential for inexpensive,environmentally-friendly,and waste-free manufacturing of Cu_(2)Se.

关键词： Cu_(2)Se berzelianite nanocrystalline semiconductor mechanochemical synthesis planetary ball mill

Mesenchymal stem cell secretome and nanotechnology:Combining therapeutic strategies

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BIOCEll 2022年第8期46卷 1807-1813页

作者： ADRIANA l.FERREIRA GUSTAVO C.PARIS AlINE DE A.AZEVEDO erika A.C.CORTEZ SIMONE N.CARVAlHO lAIS DE CARVAlHO AlESSANDRA A.THOlE laboratory of Stem Cell Research Roberto Alcantara Gomes Biology InstituteRio de Janeiro State UniversityRio de Janeiro20540170Brazil

Mesenchymal stem cells(MSC)have pushed the field of stem cell-based therapies by inducing tissue regeneration,immunosuppression,and angiogenesis mainly through vesicles and soluble factors release(paracrine signaling).MSC-extracellular vesicles(MSC-EV)adaptable secretome and homing to injured sites allowed researchers to unlock a new era of cell-free based *** parallel,nanoparticles(NP)have been explored in contributing to transport and drug delivery systems,giving drugs desired physical-chemical properties to exploit cell ***,NPs can be quickly recognized by immune cells and cleared from *** this viewpoint,we explore how combining both therapeutic strategies can improve efficacy and circumvent limitations of both *** benefit from the potent MSC membrane composition,guiding chemotaxis to tumor sites,a very restricted ***-EV has low immunogenicity,high stability,long half-life and can explore tissue targeting ligands as a precise drug carry,even across biological *** properties promote enhanced targeted drug delivery that can be combined with NP,exploring biological membrane production through:*** cell therapy with NP-infused MSC;***-containing MSC-EV generated by NP-infused MSC;*** coating NP in MSC membrane(“MSC NanoGhosts”),allowing precise cargo definition without losing ***,nanotechnology combined with cell-based therapeutic resources can greatly improve targeted drug delivery,improving efficacy and opening a new venue of therapeutic possibilities.

关键词： Mesenchymal stem cells Nanoparticles Secretome Exosome Targeted drug delivery

Physical activity during pregnancy and the role of theory in promoting positive behavior change:A systematic review

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运动与健康科学（英文） 2017年第2期6卷 198-206页

作者： erika.l.thomp.on Cheryl A.Vamos Ellen M.Daley Department of Community and Family Health University of South Florida Tampa FL 33612 USA

Background: Physical activity(PA) during pregnancy provides physical and psychological benefits for mother and child. U.S. guidelines recommend ≥30 min of moderate exercise for healthy pregnant women most days of the week; however, most women do not meet these recommendations. Theory assists in identifying salient determinants of health behavior to guide health promotion interventions; however, the application of theory to examine PA among pregnant women has not been examined cohesively among multiple levels of influence(e.g.,intrapersonal, interpersonal, neighborhood/environmental, and organizational/political). Subsequently, this systematic review aims to identify and evaluate the use of health behavior theory in studies that examine PA during ***: Articles published before July 2014 were obtained from Pub Med and Web of Science. Inclusion criteria applied were:(1) empiricallybased;(2) peer-reviewed;(3) measured factors related to PA;(4) comprised a pregnant sample; and(5) applied theory. Fourteen studies were included. Each study's application of theory and theoretical constructs were ***: Various theories were utilized to explain and predict PA during pregnancy; yet, the majority of these studies only focused on intrapersonal level determinants. Five theoretical frameworks were applied across the studies—all but one at the intrapersonal level. Few determinants identified were from the interpersonal, neighborhood/environmental, or organizational/political ***: This systematic review synthesized the literature on theoretical constructs related to PA during pregnancy. Interpersonal, community,and societal levels remain understudied. Future research should employ theory-driven multi-level determinants of PA to reflect the interacting factors influencing PA during this critical period in the life course.

关键词：行为理论妊娠期系统身体评价怀孕期间人际关系社区环境

Rice(Oryza sativa l.)plant protection using dual biological control and plant growth-promoting agents:Current scenarios and future prospects

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Pedosphere 2023年第2期33卷 268-286页

作者： Debasis MITRA Sergio DE lOS SANTOS-VIllAlOBOS Fannie Isela PARRA-COTA Ana María Garcia MONTElONGO erika.l.rena BlANCO Vanessa l.lIRA Adeyemi N.OlATUNBOSUN Bahman KHOSHRU Rittick MONDAl Parameswaran CHIDAMBARANATHAN Periyasamy PANNEERSElVAM Pradeep K.DAS MOHAPATRA Department of Microbiology Raiganj UniversityRaiganjUttar DinajpurWest Bengal 733134(India) Instituto Tecnológico de Sonora 5 de febrero 818.Col.CentroCd.ObregónSonora 85000(Mexico) Campo Experimental Norman E.Borlaug-Instituto Nacional de Investigaciones Forestales Agrícolas y Pecuarias(INIFAP)Norman E.Borlaug Km.12C.P.Ciudad ObregónSonora 85000(Mexico) laboratorio de Investigación en Biotecnología y Química de Polímeros Decanato de InvestigaciónUniversidad Nacional Experimental del TáchiraSan Cristóbal 5001(Venezuela) Departamento de Micologia Federal University of PernambucoRecifePE 50670-901(Brazil) Department of Plant Physiology and Crop Production Federal University of AgricultureAbeokuta 111101(Nigeria) Department of Soil Science Faculty of AgricultureUniversity of TabrizTabriz 51664(Iran) Department of Sericulture Raiganj UniversityRaiganjUttar DinajpurWest Bengal 733134(India) Biotechnology Crop Improvement DivisionIndian Council of Agricultural Research(ICAR)-National Rice Research InstituteCuttackOdisha 753006(India) Microbiology Crop Production DivisionICAR-National Rice Research InstituteCuttackOdisha 753006(India) Professor A.K.Bothra Environment Conservation Centre Raiganj UniversityRaiganjUttar DinajpurWest Bengal 733134(India)

Various microorganisms live in association with different parts of plants and can be harmful,neutral,or beneficial to plant *** microbial inhabitants of plants can control plant diseases by contesting with,predating on,or antagonizing plant pathogens and by inducing systems for plant defense.A range of methods,including plant growth-promoting microorganisms(PGPMs)as biological control agents(BCAs)(BCA-PGPMs)are used for the biological management and control of plant *** BCAs interact with plants by inducing resistance or priming plants without direct interaction with the *** BCAs operate via nutrient competition or other mechanisms to modulate the growth conditions for the ***,PGPMs can be applied alone or together with other chemicals or carriers to control various crop *** review highlights the effective types of BCA-PGPMs and their applications,roles,carrier based-formulations,and responses to rice(Oryza sativa l.)*** plant disease management prospects are promising,and growers’increasing demand for BCA-PGPM products can be exploited as an effective approach to the management of plant diseases,as well as to improve yield,environmental protection,biological resources,and agricultural system sustainability.

关键词： biological control agent plant disease plant growth-promoting microorganism plant health plant pathogen

Quality of monkeypox information in Wikipedia across multiple languages

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Asian Pacific Journal of Tropical Medicine 2022年第12期15卷 571-572页

作者： Eric David B.Ornos Jared Gabriel l.Dela Rosa Jea Giezl N.Solidum Jervy P.Garcia erika P.Ong Rafael lorenzo G Valenzuela Ourlad Alzeus G.Tantengco College of Medicine University of the Philippines ManilaErmitaManilaPhilippines Department of Family and Community Medicine Eastern Visayas Medical CenterTacloban CityPhilippines

In recent years,the Internet has become the primary source of health information for the general population,which may be attributed to improvements in digital technology and Internet accessibility[1].Since the World Health Organization declared the coronavirus disease (COVID-19) as a pandemic in March 2020[2],digital information has gained more importance,as seen through the rapid growth in the number of people searching online[3].As seen from previous infectious disease outbreaks,the recent increase in monkeypox cases might compel individuals worldwide to broaden their searches for relevant virtual health information[3,4].

关键词： Wikipedia individual online

Short-term microbial responses to soluble inorganic P input in a tropical lowland rain forest in Amazonia

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Pedosphere 2021年第6期31卷 964-972页

作者： Yuri W.l.DE SOUSA erika BUSCARDO Carlos A.N.QUESADA Henrique E.M.NASCIMENTO laszlo NAGY National Research Institute for Amazonia Manaus 69067-375(Brazil) Department of Forestry University of BrasiliaBrasilia 70910-900(Brazil) Centre for Functional Ecology University of CoimbraCoimbra 3000-456(Portugal) Department of Animal Biology University of CampinasCampinas 13083-862(Brazil)

In non-flooded lowland rain forests with low soil phosphorus(P)in parts of Amazonia,P cycling largely occurs via leaf litter recycling by arbuscular mycorrhizal(AM)fungal *** high input of P into these ecosystems occurs during drought years with increased *** the length and frequency of drought events are projected to increase in the region,a single-dose nutrient addition experiment was carried out to test how this would impact P *** application rate of 4 kg P ha^(-1) was used,which corresponds to twice the amount of litter-derived P in an average *** was hypothesized that i)the added mineral P would be immobilized by soil microorganisms,leading to measurable increase in soil microbial biomass carbon(C)and P and ii)AM colonization rate would be reduced by the pulse in mineral P available for plant *** results did not support either of our *** addition of P did not have an effect on AM root colonization,nor was P immobilized by soil microbiota during the experimental *** lack of a difference between the control and treatment at our study site could be attributed to the relatively low one-off dose of P applied that did not change either the colonization rate of roots by AM fungi or the amount of soil available labile *** obtain a mechanistic understanding of the availability,capture,and use of P by plant-symbiont associations in tropical rain forest ecosystems,further integrated studies of the soil-plant system combining long-term nutrient manipulations,modeling,and experimental approaches are required.

关键词： Amazon basin arbuscular mycorrhizal fungi nutrient addition phosphorus cycling soil microbial biomass