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商业周刊（中文版） 2014年第14期 46-47页

作者： Nick Summers Jacob Barach Joseph Ciolli eric lam 小本

美国股市过去五年中上涨了近两倍。

关键词：美国股市投资者华尔街

优化检测制程设计加速改善65nm芯片的良率

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电子工业专用设备 2008年第3期37卷 38-42页

作者： Sang Chong eric Rying Alexa Perry Stephen lam Mary Ann St Lawrence IBM微电子部Hopewell Junction PDf Solutions KLA-Tencor Corporation Hopewell Junction

描述一种广泛应用于探索制程设计方面的系统性及随机性故障的短流程测试芯片与先进的检测工具平台相结合的综合方法,以对在65nm技术节点上的关键性缺陷进行特征化描述和监控,借此加速基于缺陷的良率学习。通过独特的快速电性测试方案、... 详细信息

描述一种广泛应用于探索制程设计方面的系统性及随机性故障的短流程测试芯片与先进的检测工具平台相结合的综合方法,以对在65nm技术节点上的关键性缺陷进行特征化描述和监控,借此加速基于缺陷的良率学习。通过独特的快速电性测试方案、快速分析软件以及优化的检测效果,可缩短快速制程开发的学习周期。通过将在一个领先的300mm晶片厂得到的CV检测设置知识经验成功运用于制造过程,优化了产品的关键缺陷(DOI)检测。

关键词：特征化载具测试芯片缺陷检测缺陷叠置分析 S/N分析 KLA—Tencor 2800 制程-设计互动

Distinctive serotypes of SARS-related coronaviruses defined by convalescent sera from unvaccinated individuals

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hLife 2023年第1期1卷 26-34页

作者： Chee wah Tan feng Zhu wan Ni Chia #Barnaby EYoung Aileen Ying Yan Yeoh Thomas Althaus Chee fu Yung wee Chee Yap Beng Lee Lim Mark I-C Chen Jinyan Zhang Yun Yan Mah eric Voiglio Alex Sigal Jianxin Huo Shengli Xu Yee Joo Tan Kong-Peng lam David Lye Lin-fa wang Programme in Emerging Infectious Diseases Duke-NUS Medical SchoolSingapore National Center of Infectious Diseases Singapore Tan Tock Seng Hospital Singapore Lee Kong Chian School of Medicine Nanyang Technology UniversitySingapore Centre Scientifique de Monaco Monaco Direction de I’Action Sanitaire de Monaco Monaco Infectious Disease Service Department of PediatricsKK Women’s and Children’s HospitalSingapore Duke-NUS Medical School Singapore African Health Research Institute DurbanSouth Africa Singapore Immunology Network Agency for ScienceTechnology and ResearchSingapore Department of Physiology Yong Loo Lin School of MedicineNational University of SingaporeSingapore Department of Microbiology and Immunology Yong Loo Lin School of MedicineNational University of SingaporeSingapore Infectious Diseases Translational Research Programme National University of SingaporeSingapore 14School of Biological SciencesNanyang Technological UniversitySingapore Singhealth Duke-NUS Global Health Institute Singapore

Multiple Omicron sub-lineages have emerged,with Omicron XBB and XBB.1.5 subvariants becoming the dominant variants globally at the time of this *** key feature of new variants is their ability to escape humoral immunity despite the fact that there are limited genetic changes from their preceding *** raises the question of whether Omicron should be regarded as a separate serotype from viruses serologically clustered with the ancestral severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)***,we present cross-neutralization data based on a pseudovirus neutralization test using convalescent sera from naïve individuals who had recovered from primary infection by SARS-CoV-1 and SARS-CoV-2 strains/variants including the ancestral virus and variants Beta,Delta,Omicron BA.1,Omicron BA.2 and Omicron *** results revealed no significant cross-neutralization in any of the three-way testing for SARS-CoV-1,ancestral SARS-CoV-2 and SARS-CoV-2 Omicron *** data argue for the assignment of three distinct serotypes for the currently known human-infecting SARS-related coronaviruses.

关键词： SARS-CoV-2 SARS-CoV-1 serotype Omicron primary infection convalescent sera

The economic burden of influenza-associated outpatient visits and hospitalizations in China: a retrospective survey

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Infectious Diseases of Poverty 2015年第1期4卷 371-381页

作者： Juan Yang Mark Jit Kathy S.Leung Ya-ming Zheng Lu-zhao feng Li-ping wang eric H.Y.Lau Joseph T.wu Hong-jie Yu Key Laboratory of Surveillance and Early-warning on Infectious Disease Division of Infectious DiseaseChinese Center for Disease Control and Prevention155 Changbai RoadChangping DistrictBeijing 102206China Modelling and Economics Unit of Public Health in England LondonUK Department of Infectious Disease Epidemiology London School of Hygiene and Tropical MedicineLondonUK wHO Collaborating Centre for Infectious Disease Epidemiology and Control School of Public HealthLi Ka Shing Faculty of MedicineThe University of Hong Kong2/F North WingPatrick Manson Building7 Sassoon RoadPok Fu LamHong Kong Special Administrative RegionChina

Background:The seasonal influenza vaccine coverage rate in China is only 1.9%.There is no information available on the economic burden of influenza-associated outpatient visits and hospitalizations at the national level,even though this kind of information is important for informing national-level immunization policy ***:A retrospective telephone survey was conducted in 2013/14 to estimate the direct and indirect costs of seasonal influenza-associated outpatient visits and hospitalizations from a societal *** participants were laboratory-confirmed cases registered in the National Influenza-like Illness Surveillance Network and Severe Acute Respiratory Infections Sentinel Surveillance Network in China in ***-reported costs from the survey were validated by a review of hospital accounts for a small sample of the ***:The study enrolled 529 outpatients(median age:eight years;interquartile range[IQR]:five to 20 years)and 254 inpatients(median age:four years;IQR:two to seven years).Among the outpatients,22.1%(117/529)had underlying diseases and among the inpatients,52.8%(134/254)had underlying *** average total costs related to influenza-associated outpatient visits and inpatient visits were US$155(standard deviation,SD US$122)and US$1,511(SD US$1,465),*** medical costs accounted for 45 and 69%of the total costs related to influenza-associated outpatient and inpatient visits,*** influenza outpatients,the mean cost per episode in children aged below five years(US$196)was higher than that in other age groups(US$129–153).for influenza inpatients,the mean cost per episode in adults aged over 60 years(US$2,735)was much higher than that in those aged below 60 years(US$1,417–1,621).Patients with underlying medical conditions had higher costs per episode than patients without underlying medical conditions(outpatients:US$186 ***$146;inpatients:US$1,800 ***$1,189).In the baseline ana

关键词： Influenza Cost analysis China

Risk factors for fracture in adult kidney transplant recipients

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world Journal of Transplantation 2016年第2期6卷 370-379页

作者： Kyla L Naylor Guangyong Zou william D Leslie Anthony B Hodsman Ngan N lam eric McArthur Lisa-Ann fraser Gregory A Knoll Jonathan D Adachi S Joseph Kim Amit X Garg Institute for Clinical Evaluative Sciences 2nd Institute of Health Policy Management and EvaluationUniversity of Toronto Department of Epidemiology and Biostatistics Western University Department of Medicine University of Manitoba Division of Nephrology Western University Division of Nephrology University of Alberta Division of Endocrinology Western University Division of Nephrology Kidney Research CentreOttawa Hospital Research InstituteUniversity of Ottawa Division of Rheumatology McMaster University Division of Nephrology University Health NetworkUniversity of Toronto

AIM: To determine the general and transplant-specific risk factors for fractures in kidney transplant ***: we conducted a cohort study of all adults who received a kidney-only transplant(n = 2723) in Ontario, Canada between 2002 and 2009. we used multivariable Cox proportional hazards regression to determine general and transplant-specific risk factors for major fractures(proximal humerus, forearm, hip, and clinical vertebral). The final model was established using the backward elimination strategy, selecting risk factors with a P-value ≤ 0.2 and forcing recipient age and sex into the model. we also assessed risk factors for other fracture locations(excluding major fractures, and fractures involving the skull, hands or feet). RESULTS: There were 132 major fractures in the follow-up(8.1 fractures per 1000 person-years). General risk factors associated with a greater risk of major fracture were older recipient age [adjusted hazard ratio(a HR) per 5-year increase 1.11, 95%CI: 1.03-1.19] and female sex(a HR = 1.81, 95%CI: 1.28-2.57). Transplant-specific risk factors associated with a greater risk of fracture included older donor age(5-year increase)(a HR = 1.09, 95%CI: 1.02-1.17) and end-stage renal disease(ESRD) caused by diabetes(a HR = 1.72, 95%CI: 1.09-2.72) or cystic kidney disease(a HR = 1.73, 95%CI: 1.08-2.78)(compared to glomerulonephritis as the reference cause). Risk factors across the two fracture locations were not consistent(major fracture locations vs other). Specifically, general risk factors associated with an increased risk of other fractures were diabetes and a fall with hospitalization prior to transplantation, while length of time on dialysis, and renal vascular disease and other causes of ESRD were the transplant-specific risk factors associated with a greater risk of other ***: Both general and transplant-specific risk factors were associated with a higher risk of fractures in kidney transplant recipients. Results ca

关键词： fracture Risk factors Kidney transplant recipient Prognostication Cohort study

Impact of exercise on neuro-cognitive function and hippocampal plasticity in early psychosis—a preliminary data analysis

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Impact of exercise on neuro-cognitive function and hippocamp...