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Transcranial direct current stimulation for auditory verbal hallucinations:a systematic review of clinical trials

Neural Regeneration Research 2021年第4期16卷 666-671页

作者： Samaneh Rashidi Myles Jones eric murillo-rodriguez Sergio Machado Youguo Hao Ali Yadollahpour Department of Medical Physics School of MedicineAhvaz Jundishapur University of Medical SciencesAhvazIran Department of Psychology University of SheffieldSheffieldUK Laboratorio de Neurociencias Moleculares e Integrativas Escuela de Medicina División Ciencias de la SaludUniversidad Anáhuac MayabMéridaYucatánMéxico Laboratory of Physical Activity Neuroscience Physical Activity Sciences Postgraduate ProgramSalgado de Oliveira UniversityNiteróiBrazil Department of Rehabilitation Shanghai Putuo People’s HospitalShanghaiChina

Transcranial direct current stimulation(tDCS)has been reportedly beneficial for different neurodegenerative *** has been reported as a potential adjunctive or alternative treatment for auditory verbal hallucination(AVH).This study aims to review the effects of tDCS on AVH in patients with schizophrenia through combining the evidence from randomized clinical trials(RCTs).The databases of PsycINFO(2000–2019),PubMed(2000–2019),EMBASE(2000–2019),CINAHL(2000–2019),Web of Science(2000–2019),and Scopus(2000–2019)were systematically *** clinical trials with RCT design were selected for final analysis.A total of nine RCTs were eligible and included in the *** RCTs were included in the final *** them,six RCTs reported a significant reduction of AVH after repeated sessions of tDCS,whereas three RCTs did not show any advantage of active tDCS over sham *** current studies showed an overall decrease of approximately 28%of AVH after active tDCS and 10%after sham *** tDCS protocols targeting the sensorimotor frontal-parietal network showed greater treatment effects compared with the protocols targeting other *** this regard,cathodal tDCS over the left temporoparietal area showed inhibitory effects on *** most effective tDCS protocol on AVHs was twice-daily sessions(2 mA,20-minute duration)over 5 consecutive days(10 sessions)with the anode over the left dorsolateral prefrontal cortex and the cathode over the left temporal *** patient-specific and diseasespecific factors such as young age,nonsmoking status,and higher frequencies of AVHs seemed to be the predictors of treatment *** together,the results of tDCS as an alternative treatment option for AVH show controversy among current literatures,since not all studies were ***,the studies targeting the same site of the brain showed that the tDCS could be a promising treatment option to reduce *** RCTs,with larger sample sizes,should be con

关键词： auditory verbal hallucinations dorsolateral prefrontal cortex effective protocol randomized clinical trial,schizophrenia temporoparietal area transcranial direct current stimulation treatment efficacy

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Standardization of exercise intensity and consideration of a dose-response is *** on "Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models”,by Lourenco et al.,published 2019 in Nature Medicine

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Journal of Sport and Health Science 2019年第4期8卷 353-354页

作者： Thomas Gronwald Ana Cristina de Bem Alves eric murillo-rodriguez Alexandra Latini Juliane Schuette Henning Budde Faculty of Health Sciences Department of PerformanceNeuroscienceTherapy and HealthMedical School HamburgUniversity of Applied Science and Medical UniversityHamburg 20457Germany LABOX Department of BiochemistryCenter for Biological SciencesFederal University of Santa CatarinaFlorianopolisSanta Catarina 88040-900Brazil Medicine School Division of Health SciencesAnahuac Mayab UniversityMeridaYucatan 97310Mexico Faculty of Human Sciences Medical School HamburgUniversity of Applied Science and Medical UniversityHamburg 20457Germany

Over the past decade,several biochemical pathways have been investigated to understand the underlying mechanisms involved in the beneficial effects of physical exercise on cognition.1,2 Lourenco et al.,3 in an elegant study published in Nature Medicine,examined the relationship between exercise training and hippocampal memory ***,the authors showed that FNDC5/irisin is an important mediator of beneficial effects of physical exercise in a mouse model of Alzheimer's disease.

关键词： exercise intensity dose-response Alzheimer's models

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Hirschsprung's disease associated enterocolitis:A comprehensive review

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World Journal of Clinical Pediatrics 2023年第3期12卷 68-76页

作者： eric M Gershon Leonel rodriguez Ricardo A Arbizu Section of Pediatric Gastroenterology Yale University School of MedicineNew HavenCT 06520United States

Hirschsprung’s disease(HSCR)is a congenital disorder characterized by failure of the neural crest cells to migrate and populate the distal bowel during gestation affecting different lengths of intestine leading to a distal functional *** treatment is needed to correct HSCR once the diagnosis is confirmed by demonstrating the absence of ganglion cells or aganglionosis of the affected bowel ***’s disease associated enterocolitis(HAEC)is an inflammatory complication associated with HSCR that can present either in the pre-or postoperative period and associated with increased morbidity and *** pathogenesis of HAEC remains poorly understood,but intestinal dysmotility,dysbiosis and impaired mucosal defense and intestinal barrier function appear to play a significant *** is no clear definition for HAEC,but the diagnosis is primarily clinical,and treatment is guided based on ***,we aim to provide a comprehensive review of the clinical presentation,etiology,pathophysiology,and current therapeutic options for HAEC.

关键词： Hirschsprung’s Enterocolitis Pathogenesis Microbiome Dysbiosis Dysmotility Treatment

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High efficiency GHz laser processing with long bursts

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International Journal of Extreme Manufacturing 2023年第1期5卷 202-210页

作者： eric Audouard eric Mottay Amplitude PessacFrance

Bursts of GHz repetition rate pulses involve more ablation mechanisms than single femtosecond *** ablation by GHz laser pulses is a multi-step process,consisting of a first thermal incubation phase,followed by a highly efficient ablation *** ablation therefore combines thermal and non-thermal ablation *** an optimal choice of the burst duration,the ablation efficiency can be highly *** bursts,comprising tens of pulses to hundreds of pulses,are needed to take full advantage of the increase in ablation efficiency.

关键词： femtosecond laser temporal pulses shaping GHz bursts femtosecond processing

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Longitudinal assessment of liver stiffness by transient elastography for chronic hepatitis C patients

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World Journal of Clinical Cases 2022年第17期10卷 5566-5576页

作者： Anya Mezina Arunkumar Krishnan Tinsay A Woreta Kevin B Rubenstein eric Watson Po-Hung Chen Carla rodriguez-Watson Department of Medicine Johns Hopkins School of MedicineBaltimoreMD 21287United States Division of Gastroenterology and Hepatology Johns Hopkins School of MedicineBaltimoreMD 21231United States Mid-Atlantic Permanente Research Institute Kaiser Permanente Mid-Atlantic StatesRockville 20852United States Department of Health Policy and Management Bloomberg School of Public HealthJohns Hopkins UniversityBaltimoreMD 21287United States Innovation in Medical Evidence Development and Surveillance(IMEDS)Program Reagan-Udall Foundation for the FDAWashington20036United States

BACKGROUND Liver fibrosis is a common pathway of liver injury and is a feature of most chronic liver *** progression varies markedly in patients with hepatitis C virus(HCV).Liver stiffness has been recommended as a parameter of fibrosis progression/regression in patients with *** To investigate changes in liver stiffness measured by transient elastography(TE)in a large,racially diverse cohort of United States patients with chronic hepatitis C(CHC).METHODS We evaluated the differences in liver stiffness between patients treated with direct-acting antiviral(DAA)therapy and untreated *** had≥2 TE measurements and no prior DAA *** used linear regression to measure the change in liver stiffness between first and last TE in response to treatment,controlling for age,sex,race,diabetes,smoking status,human immunodeficiency virus status,baseline alanine aminotransferase,and baseline liver *** regression models analyzed the change in liver stiffness as measured by kPa,stratified by cirrhosis *** Of 813 patients,419(52%)initiated DAA *** liver stiffness was 12 kPa in 127(16%).Median time between first and last TE was 11.7 and 12.7 mo among treated and untreated patients,*** was no significant change in liver stiffness observed over time in either the group initiating DAA treatment(0.016 kPa/month;CI:-0.051,0.084)or in the untreated group(0.001 kPa/mo;CI:-0.090,0.092),controlling for covariates.A higher baseline kPa score was independently associated with decreased liver *** DAA treatment was not associated with a differential change in liver stiffness over time in patients with CHC compared to untreated patients.

关键词： Chronic hepatitis C Liver stiffness Cirrhosis Transient elastography Direct-acting antiviral therapy

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Unlocking the monolithic integration scenario: optical coupling between GaSb diode lasers epitaxially grown on patterned Si substrates and passive SiN waveguides

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Light(Science & Applications) 2023年第7期12卷 1381-1390页

作者： Andres Remis Laura Monge-Bartolome Michele Paparella Audrey Gilberto Guilhem Boissier Marco Grande Alan Blake Liam O'Faolain Laurent Cerutti Jean-Baptiste rodriguez eric Tournie ES University of MontpellierCNRSF-34000 MontpellierFrance Department of Electrical and Information Engineering Polytechnic University of Bari4 Via E OrabonaIT-70126 BariItaly Tyndall National Institute Lee Maltings ComplexDyke ParadeIR-T12R5CP CorkIreland Centre for Advanced Photonics and Process Analysis Munster Technological UniversityBishopstownIR-T12P928 CorkIreland

Silicon(Si)photonics has recently emerged as a key enabling technology in many application fields thanks to the mature Si process technology,the large silicon wafer size,and promising Si optical *** monolithic integration by direct epitaxy of III-V lasers and Si photonic devices on the same Si substrate has been considered for decades as the main obstacle to the realization of dense photonics *** considerable progress in the last decade,only discrete III-V lasers grown on bare Si wafers have been reported,whatever the wavelength and laser *** we demonstrate the first semiconductor laser grown on a patterned Si photonics platform with light coupled into a waveguide.A mid-IR GaSb-based diode laser was directly grown on a pre-patterned Si photonics wafer equipped with SiN waveguides clad by SiO_(2).Growth and device fabrication challenges,arising from the template architecture,were overcome to demonstrate more than 10 mw outpower of emitted light in continuous wave operation at room *** addition,around 10%of the light was coupled into the SiN waveguides,in good agreement with theoretical calculations for this butt-coupling *** work lft an important building block and it paves the way for future low-cost,large-scale,fully integrated photonic chips.

关键词： diode passive coupling

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Mid-infrared Ⅲ-Ⅴ semiconductor lasers epitaxially grown on Si substrates

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Light(Science & Applications) 2022年第7期11卷 1366-1378页

作者： eric Tournié Laura Monge Bartolome Marta Rio Calvo Zeineb Loghmari Daniel A.Díaz-Thomas Roland Teissier Alexei N.Baranov Laurent Cerutti Jean-Baptiste rodriguez IES University of MontpellierCNRS34000 MontpellierFrance

There is currently much activity toward the integration of mid-infrared semiconductor lasers on Si substrates for developing a variety of smart,compact,sensors based on Si-photonics integrated *** review this rapidly-evolving research field,focusing on the epitaxial integration of antimonide lasers,the only technology covering the whole mid-to-far-infrared spectral *** explain how a dedicated molecular-beam epitaxy strategy allows for achieving high-performance GaSb-based diode lasers,InAs/AlSb quantum cascade lasers,and InAs/GaInSb interband cascade lasers by direct growth on on-axis(001)Si substrates,whereas GaAs-on-Si or GaSb-on-Si layers grown by metal-organic vapor phase epitaxy in large capability epitaxy tools are suitable templates for antimonide laser *** also show that etching the facets of antimonide lasers grown on Si is a viable approach in view of photonic integrated ***,this review shows that while diode lasers are sensitive to residual crystal defects,the quantum cascade and interband cascade lasers grown on Si exhibit performances comparable to those of similar devices grown on their native substrates,due to their particular band structures and radiative recombination *** device lifetimes have been extrapolated for interband cascade ***,routes to be further explored are also presented.

关键词： epitaxial quantum template

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Artificial urinary sphincter surgery in the special populations:neurological,revision,concurrent penile prosthesis and female stress urinary incontinence groups

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Asian Journal of Andrology 2020年第1期22卷 45-50页

作者： eric Chung AndroUrology Centre BrisbaneQLD 4000Australia University of Queensland Princess Alexandra HospitalBrisbaneQLD 4000Australia Macquarie University Hospital SydneyNSW 2109Australia

The artificial urinary sphincter(AUS)remains the standard of care in men with severe stress urinary incontinence(SUI)following prostate surgery and *** the current AUS provides an effective,safe,and durable treatment option,it is not without its limitations and complications,especially with regard to its utility in some“high-risk”*** article provides a critical review of relevant publications pertaining to AUS surgery in specific high-risk groups such as men with spinal cord injury,revision cases,concurrent penile prosthesis implant,and female *** discussion of each category includes a brief review of surgical challenge and a practical action-based set of *** increased understandings of the pathophysiology of various SUI cases coupled with effective therapeutic strategies to enhance AUS surgery continue to improve clinical outcomes of many patients with SUI.

关键词： artificial urinary sphincter female stress incontinence penile prosthesis implant revision surgery spinal cord injury urinary incontinence

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Penile prosthesis implant in the special populations:diabetics,neurogenic conditions,fibrotic cases,concurrent urinary continence surgery,and salvage implants

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Asian Journal of Andrology 2020年第1期22卷 39-44页

作者： eric Chung AndroUrology Centre BrisbaneQLD 4000Australia University of Queensland Princess Alexandra HospitalBrisbaneQLD 4000Australia Macquarie University Hospital SydneyNSW 2109Australia

Penile prosthesis implant(PPI)remains an effective and safe treatment option for men with erectile dysfunction(ED).However,PPI surgery can be associated with a higher risk of complications in certain *** article provides a critical review of relevant publications pertaining to PPI in men with diabetes,significant corporal fibrosis,spinal cord injury,concurrent continence surgery,and complex salvage *** discussion of each category of special populations includes a brief review of the surgical challenges and a practical action-based set of *** specific patient populations posed considerable challenges in PPI surgery,strict pre-and postoperative management coupled with safe surgical practice is a prerequisite to achieving excellent clinical outcomes and high patient satisfaction rate.

关键词： continence surgery diabetes erectile dysfunction penile prosthesis implant Peyronie’s disease priapism salvage surgery spinal cord injury

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Photocatalytic degradation of dye effluent by titanium dioxide pillar pellets in aqueous solution

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Journal of Environmental Sciences 2004年第3期16卷 375-379页

作者： eric Hu School of Engineering and Technology

Photocatalytic oxidation(PCO) process is an effective way to deal with organic pollutants in wastewater which could be difficult to be degraded by conventional biological treatment methods. Normally the TiO 2 powder in nanometre size range was directly used as photocatalyst for dye degradation in wastewater. However the titanium dioxide powder was arduous to be recovered from the solution after treatment. In this application, a new form of TiO 2(i. e. pillar pellets ranging from 2 5 to 5 3 mm long and with a diameter of 3 7 mm) was used and investigated for photocatalytic degradation of textile dye effluent. A test system was built with a flat plate reactor(FPR) and UV light source(blacklight and solar simulator as light source respectively) for investigating the effectiveness of the new form of TiO 2. It was found that the photocatalytic process under this configuration could efficiently remove colours from textile dyeing effluent. Comparing with the TiO 2 powder, the pellet was very easy to recovered from the treated solution and can be reused in multiple times without the significant change on the photocatalytic property. The results also showed that to achieve the same photocatalytic performance, the FPR area by pellets was about 91% smaller than required by TiO 2 powder. At least TiO 2 pellet could be used as an alternative form of photocatalyst in applications for textile effluent treatment process, also other wastewater treatment processes.

关键词： dyes degradation photocatalytic reactions TiO 2 catalyst

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