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The Impact of Medical Resources and Oral Antiviral Drugs on SARS-CoV-2 Mortality—Hong Kong SAR,China,2022

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China CDC weekly 2024年第21期6卷 469-477,I0001-I0005页

作者： Zhiqi Zeng Jingyi Liang Zhijie lin Wenda Guan Wei He Qianying Li Lixi Liang Weiqi Pan Zige Liu Guibin lu Xiaoyan Deng eric HY Lau Chitin Hon Zifeng Yang Guangzhou key laboratory for clinical rapid diagnosis and early warning of infectious diseases KingMed School of Laboratory MedicineGuangzhou Medical UniversityGuangzhou CityGuangdong ProvinceChina Macao Institute of Systems Engineering Macao University of Science and TechnologyMacao SARChina Respiratory Disease AI Laboratory on Epidemic Intelligence and Medical Big Data Instrument Applications Faculty of Innovative EngineeringMacao University of Science and TechnologyMacao SARChina State Key Laboratory of Respiratory Disease National Clinical Research Center for Respiratory DiseaseGuangzhou Institute of Respiratory Healththe First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou CityGuangdong ProvinceChina School of Public Health The University of Hong KongHong Kong SARChina Laboratory of Data Discovery for Health Hong Kong SARChina Guangzhou Laboratory Guangzhou CityGuangdong ProvinceChina

Introduction:The Omicron variant of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)demonstrates increased transmissibility compared to earlier strains,contributing to a significant number of fatalities in Hong Kong Special Administrative Region(HKSAR),*** medical resources and medications are essential in mitigating these *** study evaluates the effects of supplementary resources from the Chinese mainland during the fifth wave of the pandemic in ***:Vector autoregression(VAR)was employed to analyze data from the Oxford coronavirus disease 2019(COVID-19)Government Response Tracker to assess the effectiveness of control measures during five waves of the pandemic in ***,a transmission dynamics model was created to investigate the influence of supplementary medical resources from the Chinese mainland and oral medications on ***:In the initial four waves,workplace closures,restrictions on public events,international travel bans,and shielding the elderly significantly influenced pandemic ***,during the fifth wave,these measures showed no notable *** comparing a situation without extra medical resources or COVID-19 oral medication,there was a 17.7%decrease in COVID-19 fatalities with mainland medical resources and an additional 10.2%reduction with oral ***,they contributed to a 26.6%decline in ***:With the rapid spread of the virus,regional reallocation of medical resources may reduce mortality even when the local healthcare system is overstretched.

关键词： mainland Impact travel

Optimal timing of invasive intervention for high-risk non-ST-segment-elevation myocardial infarction patients

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Journal of Geriatric Cardiology 2024年第08期 807-815页

作者： Juan-Juan ZHENG Yue-Qiao SI Tian-Yang XIA Bing-Jun lu Chun-Yu ZENG Wei-eric WANG Department of Geriatrics Southwest Hospital Third Military Medical University Department of Cardiology Daping Hospital Third Military Medical University

OBJECTIVE To compare the immediate, early, and delayed percutaneous coronary intervention(PCI) strategies in non-ST-segment-elevation myocardial infarction(NSTEMI) patients with *** Medical records of patients treated at the Daping Hospital, Third Military Medical University, Chongqing, China between 2011 and 2021 were retrospectively reviewed. Only patients with complete available information were included. All patients assigned into three groups based on the timing of PCI including immediate(linear models were *** A total of 657 patients were included in the study. The median follow-up length was 3.29(interquartile range: 1.45–4.85) years. Early PCI strategy improved the major adverse cardiac event(MACE) outcome compared to the immediate or delayed PCI strategy. Early PCI, diabetes mellitus, and left main or/and left anterior descending or/and left circumflex stenosis or/and right coronary artery ≥ 99% were predictors for MACE outcome. The optimal timing range for PCI to reduce MACE risk is 3–14 h post-admission. For high-risk NSTEMI patients, early PCI reduced primary clinical outcomes compared to immediate or delayed PCI, and the optimal timing range was 3–14 h post-admission. Delayed PCI was superior for NSTEMI with chronic kidney *** Delayed invasive strategy was helpful to reduce the incidence of MACE for high-risk NSTEMI with chronic kidney injury. An immediate PCI strategy might increase the rate of MACE.

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Capture efficiency of coal/biomass co-combustion ash in an electrostatic field

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Particuology 2018年第5期16卷 80-87页

作者： Jianyi lu Lili Fu Ximei Li eric Eddings School of Environmental Science and Engineering North China Electric Power UniversityBaoding 071003China Department of Chemzcal Engineering and Institute for Secure and Clean Energy University of UtahSalt Lake City 84112USA

Ash samples from corn stalk and coal co-fired at 0%,5%,10%,15%,20%,and 100%biomass were collected by a 4-stage wire-pipe type electrostatic precipitator (ESP),and the ratio of 14C/12C in ash samples from the 0%,20%,and 100% co-firing scenarios were measured by an accelerator mass *** differential capture efficiency in electrostatic fields for coal ash,coal/biomass co-combustion ash (co- ash),and pure biomass ash was studied separately based on the ratio 14C/*** factors that may influence capture efficiency were analyzed,including microscopic morphology,resistivity,dust density, and particle size *** results indicate that co-ash may be efficiently captured by ESP,while pure biomass ash could ***-ash capture was mainly concentrated in the first two electrostatic fields in the lab-scale ESP,and the overall capture efficiency exceeded 90%.Biomass addition decreased the resistivity of co-ash,and enhanced its surface adsorption capacity to form agglomerates,facilitating the capture of *** capture efficiency of coal ash in co-ash was higher than that of pure coal ash in the first electrostatic field of the ***-firing biomass can aid the removal of both coal ash and biomass ash when using an ESP.

关键词： Biomass Co-combustion ash (co-ash) Capture efficiency Electrical field 14C/12C

Coupled alkali feldspar dissolution and secondary mineral precipitation in batch systems: 5. Results of K-feldspar hydrolysis experiments

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Chinese Journal Of Geochemistry 2015年第1期34卷 1-12页

作者： Peng lu Hiromi Konishi eric Oelkers Chen Zhu Department of Geological Sciences Indiana University EXPEC Advance Research Center Saudi Aramco Oil Company Department of Geology Faculty of Science Niigata University Laboratoire de Geochimie CNRS 38 Rue Des Trente-Six Ponts31400 Toulouse France Earth Sciences University College London Department of Earth Sciences Zhejiang University

This paper explores how dissolution and precipitation reactions are coupled in batch reactor experimental systems at elevated temperatures. This is the fifth paper in our series of ‘‘Coupled Alkali Feldspar Dissolution and Secondary Mineral Precipitation in Batch Systems.'' In the previous four papers we presented batch experiments of alkali-feldspar hydrolysis and explored the coupling of dissolution and precipitation reactions(Fu et al. in Chem Geol91:955–964, 2009; Zhu and lu in Geochim Cosmochim Acta 73:3171–3200, 2009; Zhu et *** Geochim Cosmochim Acta 74:3963–3983, 2010; lu et al. in Appl Geochem30:75–90, 2013). Here, we present the results of additionalK-rich feldspar hydrolysis experiments at 150 °C. Our solution chemistry measurements have constrained feldspar dissolution rates, and our high resolution transmission electron microscopy work has identified boehmite precipitation. Reaction path modeling of K-feldspar dissolution and boehmite precipitation simulated the coupled reactions, but only with forced changes of boehmite rate law in the middle of experimental duration. The results which are reported in this article lend further support to our hypothesis that slow secondary mineral precipitation explains part of the wellknown apparent discrepancy between lab measured and field estimated feldspar dissolution rates(Zhu et al. in Water–rock interaction, 2004).

关键词：沉淀反应水解实验长石溶解批处理系统次生矿物碱性长石钾长石高分辨透射电子显微镜

Tea leaf’s microstructure and ultrastructure response to low temperature in indicating critical damage temperature

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Information Processing in Agriculture 2019年第2期6卷 247-254页

作者： Yongzong lu Yongguang Hu Richard LSnyder eric RKent Key Laboratory of Modern Agricultural Equipment and Technology Ministry of Education Jiangsu ProvinceJiangsu UniversityZhenjiangJiangsu 212013China Department of Land Air and Water ResourcesUniversity of CaliforniaDavisDavis 95616USA Department of Plant Sciences University of CaliforniaDavisDavis 95616USA

To find out the critical damage temperature of tea leaf,a new method of subzero treatment was provided by fitting the air temperature data from six heavy frost ***,the study explored the characteristics of Fuding Dabai tea plant response to low temperature stress of 2,0,2,4,8,10 and15C by observing the microstructure and ultrastructure changes of the *** samples were collected in an ambient temperature of 8.6C which served as *** electron microscopy(SEM)and transmission electron microscopy(TEM)were used to observe the microstructure and ultrastructure of stomata and *** observation results indicated that stomata of tea leaves have an obvious low temperature stress when the temperature was lower than2*** extent of opening of the stomata increased and enhanced guard cell protection of tea leaves against cold ***,dehydration,shrinkage and deformation of cells occurred as the temperature decreased from2C to15*** observations showed that the cell nucleus,cell walls,chloroplasts and mitochondria all had normal structure at a temperature of 8.6C where the membrane and granum lamella were clearly *** the temperature decreased to2C,the membrane system of tea leaf was the first to be damaged and the cell walls became ***,the leaf microstructure and ultrastructure showed obvious changes at2C,which might define the critical damage temperature for freeze damage of Fuding Dabai *** strategy based this critical damage temperature is useful for wind machine frost protection in tea fields within the Yangtze River region.

关键词： Frost damage Freeze injury Chill injury Frost protection

Detection and assessment of nitrogen effect on cold tolerance for tea by hyperspectral reflectance with PLSR, PCR, and LM models

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Information Processing in Agriculture 2021年第1期8卷 96-104页

作者： eric Amoah Asante Zhe Du Yongzong lu Yongguang Hu School of Agricultural Equipment Engineering Institute of Agricultural EngineeringJiangsu UniversityZhenjiangJiangsu 212013China Department of Mechanical Engineering Faculty of EngineeringKoforidua Technical UniversityKoforiduaGhana

Knowledge of nutrients effect on freezing tolerance is vital for protecting tea plants against cold injury(CI).Freezing injury treatments on tea leaves with different low temperature and nitrogen(N)concentration was evaluated by hyperspectral imaging based on the reflectance as potential analytical ***,quantitative evaluation of the CI was improved by comparing analyzed results using partial least squares regression(PLSR),principle component regression(PCR)and linear model(LM)*** of the CI was obtained by hyperspectral imaging system in the band between 871 and 1766 *** results showed that average reflectance increases with the rise of N concentration.A substantial portion of the leaf from the plant with 100%N dosage had the darkest image and resulted in the highest reflectance because the N weakened the negative effect of freezing *** of the five spectral domains tested,the best predictive accuracy for the CI of the tea leaf was achieved by PCR(R^(2)=0.9971,RMSE=0.0609)in 1410–1766 nm wavelength,followed by LM(R^(2)=0.9999,RMSE=0.0805)in 871–1000 *** whole interval had the worse prediction accuracy which could be caused by large variations in the data for a specific treatment and high absorption peak occurring around 1450 nm in the reflectance *** averages,R^(2) and RMSE for all the three statistical models showed that the worse prediction accuracy occurred in 1410–1766 nm,followed by the whole interval 871–1766 *** prediction accuracy was low which could be due to the strong water absorption peaks that appeared in both range of *** models without absorption bands had improved correlation coefficient and reduced RMSE values between the measured and the predicted CI(R^(2)=0.9676;RMSE=0.3067)compared to the model developed with the reflectance values in the entire waveband(R^(2)=0.9504;RMSE=0.6629).The reflectance values where absorption bands occurred had detrimental effect on the model performance,which

关键词： Cold injury Hyperspectral imaging Reflectance Principal component

Telomeric impact of conventional chemotherapy

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Frontiers of Medicine 2013年第4期7卷 411-417页

作者： Yiming lu Waiian Leong Olivier Guérin eric Gilson Jing Ye Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai 200025China Institut for Research on Cancer and Aging Nice(IRCAN)Nice UniversityCNRS UMR7284/INSERM U1081Faculty of MedicineNiceFrance Geriatric Unit Cimiez HospitalCHU of NiceFrance Department of Medical Genetics Archet 2 HospitalCHU of NiceFrance

The increased level of chromosome instability in cancer cells,leading to aneuploidy and gross chromosomal rearrangements,is not only a driving force for oncogenesis but also can be the Achille’s heel of the disease since many chemotherapies(CT)kill cells by inducing a non-tolerable rate of DNA damage.A wealth of published evidence showed that telomere stability can be more affected than the bulk of the genome by several conventional antineoplasic *** results raise the interesting possibility that CT with genotoxic drugs preferentially target *** agreement with this view,accelerated shortening of telomere length has been described in blood lineage cells following high-dose CT(stem cell transplantation)or non-myeloablative ***,almost nothing is known on the consequences of this shortening in terms of telomere stability,senescence and on the development of second cancers or post-treatment aging-like syndromes in cancer survivors(cognitive defect,fertility impairment,etc.).In this article,we propose:(1)telomeres of cancer cells are preferential genomic targets of chemotherapies altering chromosome maintenance;(2)telomere functional parameters can be a surrogate marker of chemotherapy sensitivity and toxicity;(3)the use of anti-telomere molecule could greatly enhance the sensitivity to standards chemotherapies.

关键词： telomere antineoplasic drugs conventional chemotherapies

Ferroelectricity Induced by Oxygen Vacancies in Rhombohedral ZrO2 Thin Films

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Energy & Environmental Materials 2024年第1期7卷 233-241页

作者： Veniero Lenzi José P.B.Silva Physics Center of Minho and Porto Universities (CF-UM-UP) University of Minho Laboratory of Physics for Materials and Emergent Technologies Lap METUniversity of Minho National Institute of Materials Physics Department of Materials Science and Metallurgy

Rhombohedral phase HfxZr1-xO2（HZO,x from 0 to 1） films are promising for achieving robust ferroelectric polarization without the need for an initial wake-up pre-cycling,as is normally the case for the more commonly ... 详细信息

关键词： charged defects ferroelectric polarization rhombohedral phase stability zirconia

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苏合香品种变迁考

中国中药杂志 2024年第6期49卷 1690-1698页

作者：丁一明吴孟华 eric Brand 孙鑫刘越郭晓晗魏胜利马双成赵中振北京中医药大学中药学院北京100029 北京中医药大学本草纲目研究所北京100029 中国食品药品检定研究院北京102629 暨南大学岭南传统中药研究中心广东广州510632 北京中医药大学中医学院北京100029 香港浸会大学中医药学院中国香港00852

苏合香为我国常用进口中药材,在汉代即传入我国,苏合香作为中药始载于《名医别录》。该文通过梳理古今中外本草、现代文献资料,并结合对苏合香产地的实地考察结果,对苏合香的名称、质量评价、基原、产地及采收加工进行了系统的品种变迁... 详细信息

苏合香为我国常用进口中药材,在汉代即传入我国,苏合香作为中药始载于《名医别录》。该文通过梳理古今中外本草、现代文献资料,并结合对苏合香产地的实地考察结果,对苏合香的名称、质量评价、基原、产地及采收加工进行了系统的品种变迁考证。结果表明,自古以来苏合香便存在基原不明、产地不清的情况。我国历代医药学家多从质地、黏稠度、气味浓度、颜色4个方面对苏合香进行质量评价。苏合香品种共发生过2次变迁,第一次变迁可能在隋唐时期,基原由南欧安息香Sty⁃rax officinalis变迁为苏合香树Liquidambar orientalis。第二次变迁在近现代,基原由苏合香树变迁为北美枫香树***。在基原第二次变迁的同时,产地发生了第一次变迁,由小亚细亚南部地区的土耳其、叙利亚等国变迁为中美洲地区及北美洲南部地区的洪都拉斯、危地马拉等国。该文对苏合香质量评价、基原、产地、性状与采收加工等多方面的历史沿革进行了考证,同时对苏合香在西方国家的应用进行了综述,可为苏合香的进一步开发利用提供历史依据。

关键词：苏合香品种基原进口药材质量评价