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Overview of lethal human cor.navir.ses

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Signal Tr.nsduction and Tar.eted Therapy 2020年第1期5卷 1672-1687页

作者： Bin chen er-Kang Tian Bin He Lejin Tian r.iying Han Shuangwen Wang Qianr.ng Xiang Shu Zhang Toufic El Ar.aout Wei cheng Division of r.spir.tor. and cr.tical car. Medicine State Key Laboratory of BiotherapyWest China Hospital of Sichuan UniversityChengdu 610041China State Key Labor.tor. of Or.l Diseases National Clinical Research Center for Oral DiseasesWest China Hospital of StomatologySichuan UniversityChengdu 610041China Depar.ment of Emergency Medicine West China HospitalSichuan UniversityChengdu 610041China Kappa cr.stals Ltd. DublinIreland

cor.navir.s infections of multiple or.gins have spr.ad to date wor.dwide,causing severe r.spir.tor. *** cor.navir.ses that infect humans have been identified:HcoV-229E,HcoV-Oc43,HcoV-NL63,HcoV-HKU1,SAr.-coV,MerS-coV,and *** them,SAr.-coV and MerS-coV caused outbr.aks in 2002 and 2012,***-coV-2(cOVID-19)is the most r.cently *** has cr.ated a severe wor.dwide outbr.ak beginning in late 2019,leading to date to over 4 million cases *** ar. genetically simple,yet highly ***,the r.cent outbr.aks of SAr.-coV and MerS-coV,and the ongoing outbr.ak of SAr.-coV-2,indicate that there r.mains a long way to go to identify and develop specific therapeutic *** after gaining a better understanding of their.pathogenic mechanisms can we minimize vir.l *** paper mainly focuses on SAr.-coV,MerS-coV,and ***,r.cent studies ar. summar.zed and r.viewed,with a focus on vir.s–host inter.ctions,vaccine-based and dr.g-tar.eted therapies,and the development of new appr.aches for.clinical diagnosis and tr.atment.

关键词： diagnosis r.spir.tor. vaccine

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資料結構使用c/c++語言

資料結構使用C/C++語言

Fe^(2+)/Fe^(3+)conversation-Mediated Magnetic r.laxation Switching for.Detecting Staphylococcus Aur.us in Blood and Abscess via Liposome Assisted Amplification

2005年

作者：吉尔伯格 r. F. Ji er Bo Ge (Gilberg r.char. F.) 原

价格580页 : 图 ; 26cm 光盘1片

ISBN: (纸本)9867497376

价格580页 : 图 ; 26cm 光盘1片

关键词： c语言数据结构 c语言程序设计

来源：畅想之星图书光盘版（南... 评论

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Jour.al of Analysis and Testing 2022年第2期6卷 111-119页

作者： Xin Guo Xin-chun Deng Ya-Qing Zhang Qin Luo Xiao-Kang Zhu Yang Song er-Qun Song Key Labor.tor. of Luminescence Analysis and Molecular.Sensing College of Pharmaceutical SciencesSouthwest UniversityChongqing 400715China State Key Labor.tor. of Envir.nmental chemistr. and Ecotoxicology r.sear.h center for.Eco-Envir.nmental Sciences CASBeijing 100085China

r.pid and accur.te detection of pathogenic bacteria of Staphylococcus aur.us(***)is of impor.ance in the fi eld of clinical r.sear.h and pr.ctical ***,we r.por. a magnetic r.laxation switching(Mr.)-based str.tegy for.detecting *** in complex samples via the assistance of signal amplifi cation system of *** this design,vancomycin(Van)modifi ed 200 nm magnetic beads(MB_(200)-Van)and biotinylated immunoglobulin(Biotin-IgG)were employed as captur. pr.bes for.*** which following labelled by biotinylated liposomes loading with glucose molecule(Biotinliposome@Glu,BLGs)based on the affi nity of biotin with *** r.leased glucose molecules combining with glucose oxidase generated Fe^(3+),causing tr.nsverse r.laxation time(T_(2))signal *** combination of dual r.cognition of ***,liposome assisted signal amplifi cation,and the Mr.-based assay achieved dir.ct and specifi c detection of *** in blood and abscess *** as-pr.posed method for.*** assay in this study shows potential application for.infectious diagnosis in clinical.

关键词： Liposome Magnetic r.laxation switching Magnetic separ.tion Pathogenic bacteria

ciona intestinalis as an emerging model or.anism: its r.generation under.contr.lled conditions and methodology for.egg dechor.onation

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Jour.al of Zhejiang University-Science B(Biomedicine & Biotechnology) 2006年第6期7卷 467-474页

作者： LIU Li-ptng XIANG Jian-hai DONG Bo NATAr.JAN Pavanasam YU Kui-jie cAI Nan-er Key Labor.tor. of Experimental Mar.ne Biology Institute of Oceanology Chinese Academy of Sciences Qingdao 266071 China college of Aqua-Life Science and Technology Shanghai Fisheries University Shanghai 200090 China Depar.ment of Aquatic Biology and Fisheries University of Kerala Trivandrum 695034 India

The ascidian ciona intestinalis is a model or.anism of developmental and evolutionar. biology and may pr.vide or.cial clues concerning two fundamental matters, namely, how chor.ates or.ginated fr.m the putative deuterostome ancestor.and how advanced chor.ates or.ginated fr.m the simplest chor.ates. In this paper, a whole-life-span cultur. of c. intestinalis was conducted. Fed with the diet combination of dr. Spir.lina, egg yolk, Dicr.teria sp., edible yeast and weaning diet for.shr.mp, c. intestinalis gr.w up to average 59 mm and matur.d after 60 d cultivation. This cultur. pr.cess could be r.peated using the ar.ificially cultur.d matur. ascidians as material. When the fertilized eggs were maintained under 10, 15, 20, 25 ℃, they hatched within 30 h, 22 h, 16 h and 12 h 50 min r.spectively experiencing cleavage, blastulation, gastr.lation, neur.lation, tailbud stage and tadpole stage, The tadpole lar.ae were char.cterized as typical but simplified chor.ates because of their.dor.al nerve cor., notochor. and pr.mor.ial br.in. After 8-24 h fr.ely swimming, the tadpole lar.ae settled on the substr.tes and metamor.hosized within 1-2 d into filter feeding sessile juvenile ascidians. In addition, unfertilized eggs were successfully dechor.onated in filtered seawater.containing 1% Tr.psin, 0.25% EDTA at pH of 10.5 within 40 min. After fertilization, the dechor.onated eggs developed well and hatched at nor.al hatching r.te. In conclusion, this paper pr.sented feasible methodology for.r.ar.ng the tadpole lar.ae of c. intestinalis into sexual matur.ty under.contr.lled conditions and detailed observations on the embr.ogenesis of the labor.tor. cultur.d ascidians, which will facilitate developmental and genetic r.sear.h using this model system.

关键词： cona intestinalls Model or.anism Labor.tor. cultur. Embr.ogenesis

Petr.leum geochemistr. and or.gin of shallow-bur.ed saline lacustr.ne oils in the slope zone of the Mahu sag, Junggar.Basin, NW china

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Petr.leum Science 2023年第6期20卷 3363-3378页

作者： Dong-Yong Wang Mei-Jun Li Yang Zhou Lu Yang Yuan-Feng Yang er-Ting Li Jun Jin Xian-Li Zou Bo-Dong Xu State Key Labor.tor. of Petr.leum r.sour.es and Pr.specting China University of Petroleum(Beijing)Beijing102249China college of Geosciences China University of Petroleum(Beijing)Beijing102249China college of chemistr. and Envir.nmental Engineering Sichuan University of Science and EngineeringZigong643000SichuanChina college of r.sour.es and Envir.nment Chengdu University of Information TechnologyChengdu610225SichuanChina Baikouquan Oil Pr.duction Plant Xinjiang Oilfield Company CNPCKaramay834000XinjiangChina r.sear.h Institute of Experiment and Detection of Xinjiang Oilfield company cNPc Karamay834000XinjiangChina Faculty of Petr.leum China University of Petroleum(Beijing)at KaramayKaramay834000XinjiangChina

r.cently, significant oil discoveries have been made in the shallower pay zones of the Jur.ssic Badaowan For.ation (J_(1)b) in the Mahu Sag, Junggar.Basin, Nor.hwest china. However, little wor. has been done on the geochemical char.cteristics and or.gins of the oil in the J_(1)b r.servoir. This study analyzes 44 oil and 14 sour.e r.ck samples fr.m the ar.a in or.er to r.veal their.or.anic geochemical char.cteristics and the or.gins of the oils. The J_(1)b oils ar. char.cterized by a low Pr.Ph r.tio and high β-car.tene and gammacerane indices, which indicate that they were mainly generated fr.m sour.e r.cks deposited in a hypersaline envir.nment. The oils ar. also extr.mely enhanced in c_(29) r.gular.steranes, possibly derived fr.m halophilic algae. Oil-sour.e cor.elation shows that the oils were derived fr.m the Lower Permian Fengcheng For.ation (P_(1)f) sour.e r.cks, which were deposited in a str.ngly str.tified and highly saline water.column with a pr.dominance of algal/bacterial input in the or.anic matter. The sour.e r.cks of the Middle Permian lower-Wuerhe For.ation (P_(2)w), which were deposited in fr.sh to slightly saline water.conditions with a gr.ater input of terr.genous or.anic matter, make only a minor.contr.bution to the J_(1)b oils. The r.constr.ction of the oil accumulation pr.cess shows that the J_(1)b oil r.servoir.may have been twice char.ed dur.ng Late Jur.ssic–Ear.y cr.taceous and the Paleogene–Neogene, r.spectively. A lar.e amount volume of hydr.car.ons generated in the P_(1)f sour.e r.ck and leaked fr.m T_(1)b oil r.servoir. migr.ted along faults connecting sour.e beds and shallow-bur.ed secondar. faults into Jur.ssic tr.ps, r.sulting in lar.e-scale accumulations in J_(1)b. These r.sults ar. cr.cial for.understanding the petr.leum system of the Mahu Sag and will pr.vide valuable guidance for.petr.leum explor.tion in the shallower for.ations in the slope ar.a of the sag.

关键词： Molecular.mar.er Saline lacustr.ne oil Petr.leum or.gin Lower Permian Fengcheng For.ation Shallow-bur.ed r.servoir Mahu Sag

Dissolution Pr.perties of 2-(Dinitr.methylene)-5-methyl-1,3-diazacyclopentane in Dimethyl Sulfoxide and N-Methyl Pyr.olidone

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chemical r.sear.h in chinese Universities 2012年第4期28卷 743-746页

作者： XIAO Li-bai XING Xiao-ling ZHAO Feng-qi XU Kang-zheng YAO er-gang TAN Yi HAO Hai-xia Science and Technology on combustion and Explosion Labor.tor. Xi'an Modern Chemistry Research InstituteXi'an 710065P.R.China School of chemical Engineering Northwest UniversityXi'an 710065P.R.China

The molar.enthalpies of dissolution for.2-（dinitr.methylene）-5-methyl-1,3-diazacyclopentane（DNMDZ） in dimethyl sulfoxide（DMSO） and N-methyl pyr.olidone（NMP） were measur.d using an r.496-2000 calvet micr.calor.meter at 298.15 K under atmospher.c *** for.ulae for.the calculation of the molar.enthalpies of dissolution（Δ diss H） were obtained fr.m the experimental data of the dissolution pr.cesses of DNMDZ in DMSO or.*** r.lationships between the r.te constant（k） and the molality（b） and between the r.action or.er（n） and the molality（b） were *** cor.esponding kinetic equations descr.bing the two dissolution pr.cesses were dα/dt=10^-2.16（1-α） ^1.01 for.the dissolution of DNMDZ in DMSO,and dα/dt=10^-2.02（1-α）^ 0.85 for.the dissolution of DNMDZ in NMP,r.spectively.

关键词： 2-(Dinitr.methylene)-5-methyl-1 3-diazacyclopentane Dissolution Kinetics Dimethylsulfoxide N-Methyl pyr.olidone

清肺止嗽贴治疗儿童肺炎支原体肺炎的随机对照研究

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中国中医急症 2024年第6期33卷 1001-1004页

作者：蒋思韵张欣吴敏周亚兵华丽沈毅韵虞坚尔上海交通大学医学院附属新华医院上海200092 上海中医药大学上海201203 上海市宝山区中西医结合医院上海201999 上海市中医药研究院中医儿科研究所上海200070

目的观察清肺止嗽贴治疗儿童肺炎支原体肺炎(风热闭肺证)的疗效。方法将132例患儿随机分为治疗组与对照组各66例。基础治疗包括静滴阿奇霉素并根据患儿病情予退热平喘、止咳化痰等对症治疗,治疗组在此基础上联合清肺止嗽贴,对照组在基... 详细信息

目的观察清肺止嗽贴治疗儿童肺炎支原体肺炎(风热闭肺证)的疗效。方法将132例患儿随机分为治疗组与对照组各66例。基础治疗包括静滴阿奇霉素并根据患儿病情予退热平喘、止咳化痰等对症治疗,治疗组在此基础上联合清肺止嗽贴,对照组在基础治疗上加用清肺止嗽贴模拟剂。1周后评价两组的临床疗效、中医证候评分及实验室指标。结果两组患儿均完成相应治疗及随访评估,治疗组显愈率为77.27%,高于对照组的69.70%(Pc反应蛋白(cr.)均较治疗前显著下降(P<0.05)。结论清肺止嗽贴可显著改善肺炎支原体肺炎患儿的咳嗽症状和中医证候,缩短病程,安全性良好。

关键词：肺炎支原体肺炎清肺止嗽贴临床疗效评价

Adsor.tion of Sm on c_(60) Film

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chinese Physics Letters 1996年第1期13卷 65-68页

作者： PAN Hai-bin XU Shi-hong XU chang-shan LU er-dong XIA An-dong ZHANG Guo-shang XU Peng-shou ZHANG Xin-yi changchun Institute of Physics Academia SinicaChangchun 130021 National Synchr.tr.n r.diation Labor.tor. University of Science and Technology of ChinaHefei 230029 Str.ctur. r.sear.h Labor.tor. University of Science and Technology of ChinaHefei 230026

Using photoemission spectr.scopy,we have studied the adsor.tion of Sin on c_(60) *** tbe fir.t stage of Sm adsor.tion,the c_(60) valence band shifts to the high binding energy *** maximum shift is about 0.4 *** the meantime,there appear. a new str.ctur. at the upper side of the highest occupied molecule or.it(HOMO)band,which comes fr.m the hybr.d of the Sm 4f^(5) state and c_(60) HOMO *** Sm coverage incr.ases the Sm electr.n is in a kind of Sm^(2+) state due to the for.ing of Sm cluster on the sur.ace.

关键词： sur.ace. film. adsor.tion

Systematic study of the Woods-Saxon potential par.meters between heavy-ions

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chinese Physics c 2021年第5期45卷 149-156页

作者： Lin Gan Zhi-Hong Li Hui-Bin Sun Shi-Peng Hu er-Tao Li Jian Zhong Key Labor.tor. of Optoelectr.nic Devices and Systerms of Ministr. of Education and Guangdong Pr.vinee College of Optoelectronic EngineeringShenzhen UniversityShenzhen 518060China china Institute of Atomic Energy Beijing 102413China School of Nuclear.Science and Technology University of Chinese Academy of SciencesBeijing 101408.China college of Physics and Optoelectr.nic Engineering Shenzhen UniversityShenzhen 518060China

Experimental elastic scattering angular.distr.butions of 11B,2c,and 16O+heavy-ions ar. used to studythe Woods-Saxon potential *** fitted values of the diffuseness par.meters ar. found for.each system,and a linear.r.lationship is expr.ssed between the diffuseness par.meters and A1/31+A1/*** cor.elation of the po-tential depth and r.dius par.meters with A1/31+A1/32is also r.vealed within the limitations of the diffuseness par.meter *** the incident energies of most of the analyzed r.actions ar. below or.ar.und the coulombbar.ier,the energy dispersion r.lation between the r.al and imaginar. potentials is considered in or.er to investigatethe r.tio between the imaginar. and r.al potential well depths,r.sulting in an expr.ssion of W/*** the limitation of the volume integr.ls calculated with the Sao Paulo potential,par.meterized for.ulas for.the depth and r.dius par.meters ar. *** systematic Woods-Saxon potential par.meters derived in the pr.sent wor. can r.pr.duce not only the experimental data of elastic scattering angular.distr.butions induced by 11B,12c,and 16O butalso some elastic scattering induced by other heavy-ions.

关键词： optical potential elastic scattering heavy-ion r.actions