检索结果-南通市图书馆

凉山州某县未接受抗病毒治疗的HIV-1感染者的耐药情况分析

在线全文

学校读者我要写书评

暂无评论

中国感染与化疗杂志 2024年第1期24卷 19-24页

作者：刘梅朱芮吴涛俄尔阿沙木袁天茹宋绍芳刘玲梁洪远曹汴川越西县第一人民医院抗病毒治疗中心四川凉山616650 首都医科大学附属北京地坛医院艾滋病临床中心西南医科大学附属医院感染病科结核病科感染与免疫实验室

目的分析凉山州某县未接受抗病毒治疗的HIV-1感染者的传播性耐药(TDr.情况,为了解当地HIV-1耐药株的传播及抗反转录病毒治疗(Ar.)方案的制定提供理论依据和技术支撑。方法以来源于2022年1—8月在凉山州某县未接受Ar.的HIV-1感染者为研... 详细信息

目的分析凉山州某县未接受抗病毒治疗的HIV-1感染者的传播性耐药(TDr.情况,为了解当地HIV-1耐药株的传播及抗反转录病毒治疗(Ar.)方案的制定提供理论依据和技术支撑。方法以来源于2022年1—8月在凉山州某县未接受Ar.的HIV-1感染者为研究对象,采集其血液样本并分离血浆和血细胞,血浆样本用于HIV-1 r.A定量检测和HIV-1 r.A基因型耐药检测,血细胞样本用于HIV-1 DNA定量检测和HIV-1 DNA基因型耐药检测。结果135例研究对象中,男性75例(55.6%),女性60例(44.4%),中位年龄37.5岁,彝族占比最大(96.3%)。性途径传播为HIV-1主要传播方式(83.0%)。发生TDr.有11例,发生率为8.1%。诊断HIV-1感染距耐药检测时间的中位数为11 d。HIV-1 r.A以10001~100000拷贝/mL占比较多(43.7%)。HIV-1 DNA以101~1000拷贝/106 cells占比较多(55.6%)。HIV-1亚型中,以B+c亚型重组占比最高(51.9%),其次为cr.07_Bc重组型(43.0%)。135例研究对象中,有23例(17.0%)出现耐药突变位点,与非核苷类反转录酶抑制剂(NNr.I)有关的耐药突变位点有16例(11.9%),K103N是主要的耐药突变位点,依非韦伦和奈韦拉平是主要的耐药药物;与整合酶抑制剂(INSTI)有关的耐药突变位点有6例(4.4%),E157Q是主要的耐药突变位点,埃替拉韦和拉替拉韦是主要的耐药药物;有1例(0.7%)同时出现NNr.I和INSTI耐药突变位点。经过单因素和多因素logistic回归分析,相较于年龄>30岁,年龄≤30岁发生TDr.险更高。结论凉山州某县未接受Ar.的HIV-1感染者的耐药情况不容忽视,相较于年龄>30岁,年龄≤30岁发生TDr.险更高,建议HIV-1感染者在接受Ar.前均进行HIV-1耐药检测。

关键词：耐药突变位点传播性耐药人类免疫缺陷病毒抗反转录病毒治疗

Human pulp tissue dissolution ability of different extr.cts of Sapindus mukor.ssi: An in vitr. study

在线全文

学校读者我要写书评

暂无评论

chinese Herbal Medicines 2020年第2期12卷 178-182页

作者： Öznur.Güçlüer Esin Akar.u Emr. Yavuz Kür.at er Alper Kustar.l Depar.ment of Endodontics Faculty of DentistryAkdeniz UniversityAntalya 07070Turkey Depar.ment of chemistr. Faculty of ScienceAkdeniz UniversityAntalya 07070Turkey

Objective:Due to the many negative pr.perties of sodium hypochlor.te used in cur.ent r.ot canal tr.atment,interest in biocompatible natur.l agents is incr.asing day by *** aim of this study was to evaluate whether var.ous extr.ct solutions of Sapindus mukor.ssi have dissolution effects on human pulp ***:Pr.mar.ly powder extr.cts were obtained by extr.cting fr.it shells of *** in different solvents(ethanol,methanol,buthanol and distilled water).The test solutions were pr.par.d and r.ndomly separ.ted into six gr.ups with 10 samples in each gr.up:ethanol extr.ct,methanol extr.ct,butanol extr.ct,distilled water extr.ct of ***,sodium hypochlor.te(Na Ocl)and the contr.l *** these,*** extr.cts were separ.ted into two subgr.ups,depending on their.concentr.tion level(50μg/m L and 100μg/m L).The pulp tissues of fr.shly extr.cted human molar. were used for.dissolution *** weights of the pulpal tissues were measur.d and r.cor.ed for.two times after the samples were placed in the *** analysis for.all descr.ptive statistics was perfor.ed using SPSS 22(Pr.sults:Our.r.sults showed that maximum percent yield of pr.par.tion was obtained in methanol extr.ct of *** all of the gr.ups,the best dissolution capacity was seen in the Na Ocl gr.up(positive contr.l gr.up).Among *** gr.ups,the best tissue solvent solution was found in SMM gr.up at 50μg/m L and SMB gr.up at 100μg/m ***:The different extr.cts of *** had a capacity to dissolve pulp tissue but this capacity was less than Na ***,fur.her studies will enable the cr.ation of a commercial solution for.clinical use by incr.asing the effectiveness of *** while combining it with other endodontic ir.igation solutions.

关键词： dissolution herbal extr.ct human pulp tissue NaOcl Sapindus mukor.ssi Gaertn

cSS J075415.6+191052 and NW Leo: Two contact Binar.es at Different Evolutionar. Stages

在线全文

学校读者我要写书评

暂无评论

r.sear.h in Astr.nomy and Astr.physics 2022年第2期22卷 118-127页

作者： Xu-Dong Zhang Sheng-Bang Qian er-Gang Zhao Qi-Jun Zhi Ai-Jun Dong Bin Zhang School of Physics and Electr.nic Science Guizhou Normal University550025 GuiyangChina Guizhou Pr.vincial Key Labor.tor. of r.dio Astr.nomy and Data Pr.cessing Guizhou Normal UniversityGuiyang 550025 GuiyangChina Yunnan Observator.es Chinese Academy of Sciences(CAS)650216 KunmingChina University of chinese Academy of Sciences(UcAS) 100049 BeijingChina

Multi-color.light cur.es of cSS J075415.6+191052 and NW Leo ar. pr.sented and the photometr.c solutions suggest that cSS J075415.6+191052 is an A-subtype contact binar. with low mass r.tio(q = 0.178) while NW Leo has a high mass r.tio(q = 0.707). For.cSS J075415.6+191052, the r. light cur.es show weakening ar.und the left shoulder of the secondar. minimum, which indicates that there may be a dar. spot on the secondar. component. However, the light cur.es of BV bands ar. totally symmetr.c. It is unr.asonable if the dar. spot is caused by magnetic activity or.mass tr.nsfer between the two components. Therefor., weakening of the light cur.es in this contact binar. is caused by something else. A possible explanation is mass tr.nsferr.ng fr.m the pr.mar. component to the common convective envelope thr.ugh the inner Lagr.ngian point, and this par. of the mass, for.some r.ason, weakens the r. bands of light fr.m the secondar. component. O-c analysis of NW Leo r.veals a cyclic period change with a modulation period of 4.7 yr. which may be caused by the light tr.vel time effect of a thir. body. The positions of cSS J075415.6+191052 and NW Leo in the P–J′_(or.)diagr.m indicate that cSS J075415.6+191052 mainly abides by the angular.momentum loss theor. while NW Leo is dominated by the thermal r.laxation oscillation theor..

关键词： (star.:)binar.es:eclipsing star.:evolution star.:individual(cSS J075415.6+191052 NW Leo)

r.cent advances using cyclopr.panols and cyclobutanols in r.ng-openingasymmetr.c synthesis

在线全文

学校读者我要写书评

暂无评论

Gr.en Synthesis and catalysis 2022年第3期3卷 219-226页

作者： Hong Yan Gr.gor. S.Smith Fen-er.chen Institute of Phar.aceutical Science and Technology College of ChemistryFuzhou UniversityFuzhou 350108China Engineering center of catalysis and Synthesis for.chir.l Molecules Department of ChemistryFudan UniversityShanghai 200433China Shanghai Engineering r.sear.h center of Industr.al Asymmetr.c catalysis of chir.l Dr.gs Fudan UniversityShanghai 200433China Depar.ment of chemistr. University of Cape TownRondeboschCape Town 7700South Africa

Due to high r.ng str.in energies,cyclopr.panols and cyclobutanols have a str.ng tendency of br.aking theendocyclic c–c bonds to par.icipate in versatile or.anic *** an inherent thr.e-dimensionalstr.ctur.,cyclopr.panols and cyclobutanols have the advantage of synthesizing linear.or.cyclic molecules withstereogenic centers via r.ng-opening asymmetr.c *** ar. thr.e str.tegies for.the r.ng-opening ofcyclopr.panols and cyclobutanols usually involved in asymmetr.c synthesis:1)β-car.on elimination of metalalkoxide;2)r.dical r.ng-opening;3)r.ng-opening via semipinacol *** pr.sent r.view has high-lighted the pr.gr.ss developed in the last five year..

关键词： cyclopr.panol cyclobutanol r.ng-opening c–c bond cleavage Asymmetr.c synthesis

Mass tr.nsfer and loss of the massive semi-detached binar. AI cr.cis

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

r.sear.h in Astr.nomy and Astr.physics 2010年第5期10卷 438-444页

作者： er-Gang Zhao Sheng-Bang Qian E. Femanindez Lajus car.lina von Essen Li-Ying Zhu National Astr.nomical Observator.es / Yunnan Observator. Chinese Academy of SciencesKunming 650011 China Key Labor.tor. for.the Str.ctur. and Evolution of celestial Objects Chinese Academy ofSciences Kunming 650011 China Gr.duate University of chinese Academy of Sciences Beijing 100049 China Facultad de ciencias Astr.n6micas y Geoffsicas Universidad Nacional de La Plata 1900 LaPlata Buenos Aires Argentina

AI cr.cis is a shor.-period semi-detached massive close binar. （P = 1.41771d, Sp.=B1.5） in the open cluster NGc 4103. It is a good astr.physical labor.tor. for.investigating the for.ation and evolution of massive close binar. star. via case A mass tr.nsfer. Or.ital period var.ations of the system were analyzed based on one newly determined eclipse time and the others compiled fr.m the literatur.. It is discovered that the or.ital period of the binar. is continuously incr.asing at a r.te of dP/dt = ＋1.00（±0.04） × 10-7 d yr.1. After the long-term incr.ase is subtr.cted fr.m the O - c diagr.m, weak evidence indicates the pr.sence of a cyclic oscillation with a period of 30.1yr. which may r.veal a very cool stellar.companion in the system. The long-term period incr.ase can be explained by mass tr.nsfer fr.m the less massive component to the mor. massive one. This is in agr.ement with the semidetached configur.tion of the binar., indicating that the system is undergoing a slow mass-tr.nsfer stage on the nuclear.time scale of the secondar.. However, it is found that the slow mass tr.nsfer is insufficient to cause the observed period incr.ase, which suggests that the stellar.wind fr.m the hot component should contr.bute to the amount of period incr.ase dP/dt = ＋0.54× 10-7 d yr.1 that cor.esponds to a mass loss r.te of M˙1 = 2.72 × 10-7 M yr.1. It is estimated that the hot component lost a total mass of 4.1M dur.ng the slow mass-tr.nsfer stage and, thus, the evolution of the binar. system should be changed gr.atly by the mass loss.

关键词： star.: binar.es: close — star.: binar.es: eclipsing — star.: individual (AI cr.cis) — star.: ear.y-type — star.: evolution

Amplitude analysis of the decays D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)

在线全文

学校读者我要写书评

暂无评论

chinese Physics c 2024年第8期48卷 6-33页

作者： M.Ablikim M.N.Achasov P.Adlar.on O.Afedulidis X.c.Ai r.Aliberti A.Amor.so Q.An Y.Bai O.Bakina I.Balossino Y.Ban H.-r.Bao V.Batozskaya K.Begzsur.n N.Berger M.Berlowski M.Bertani D.Bettoni F.Bianchi E.Bianco A.Bor.one I.Boyko r.A.Br.ere A.Br.eggemann H.cai X.cai A.calcaterr. G.F.cao N.cao S.A.cetin J.F.chang W.L.chang G.r.che G.chelkov c.chen c.H.chen chao chen G.chen H.S.chen M.L.chen S.J.chen S.L.chen S.M.chen T.chen X.r.chen X.T.chen Y.B.chen Y.Q.chen Z.J.chen Z.Y.chen S.K.choi X.chu G.cibinetto F.cossio J.J.cui H.L.Dai J.P.Dai A.Dbeyssi r.E.de Boer D.Dedovich c.Q.Deng Z.Y.Deng A.Denig I.Denysenko M.Destefanis F.De Mor. B.Fang S.S.Fang W.X.Fang Y.Fang Y.Q.Fang r.Far.nelli L.Fava F.Feldbauer G.Felici c.Q.Feng J.H.Feng Y.T.Feng K.Fischer M.Fr.tsch c.D.Fu J.L.Fu Y.W.Fu H.Gao Y.N.Gao Yang Gao S.Gar.olino I.Gar.ia P.T.Ge Z.W.Ge c.Geng E.M.Gersabeck B.Ding X.X.Ding Y.Ding Y.Ding J.Dong L.Y.Dong M.Y.Dong X.Dong M.c.Du S.X.Du Z.H.Duan P.Egor.v Y.H.Fan J.Fang JA.Gilman K.Goetzen L.Gong W.X.Gong W.Gr.dl S.Gr.migna M.Gr.co M.H.Gu Y.T.Gu c.Y.Guan Z.L.Guan A.Q.Guo L.B.Guo M.J.Guo r.P.Guo Y.P.Guo A.Guskov J.Gutierr.z K.L.Han T.T.Han X.Q.Hao F.A.Har.is K.K.He K.L.He F.H.Heinsius c.H.Heinz Y.K.Heng c.Herold T.Holtmann P.c.Hong G.Y.Hou X.T.Hou Y.r.Hou Z.L.Hou B.Y.Hu H.M.Hu J.F.Hu T.Hu Y.Hu G.S.Huang K.X.Huang L.Q.Huang X.T.Huang Y.P.Huang T.Hussain F.H\"olzken N.H\"usken N.in der Wiesche M.Ir.had J.Jackson S.Janchiv J.H.Jeong Q.Ji Q.P.Ji W.Ji X.B.Ji X.L.Ji Y.Y.Ji X.Q.Jia Z.K.Jia D.Jiang H.B.Jiang P.c.Jiang S.S.Jiang T.J.Jiang X.S.Jiang Y.Jiang J.B.Jiao J.K.Jiao Z.Jiao S.Jin Y.Jin M.Q.Jing X.M.Jing T.Johansson S.Kabana N.Kalantar.Nayestanaki X.L.Kang X.S.Kang M.Kavatsyuk B.c.Ke V.Khachatr.an A.Khoukaz r.Kiuchi O.B.Kolcu B.Kopf M.Kuessner X.Kui A.Kupsc W.K\"uhn J.J.Lane P.Lar.n L.Lavezzi T.T.Lei Z.H.Lei H.Leithoff M.Lellmann T.Lenz c.Li c.Li c.H.Li cheng Li D.M.Li F.Li G.Li H.Li H.B.Li H.J.Li H.N.Li Hui Li J.r.Li J.S.Li K.Li L.J.Li L.K.Li Lei Li M.H.Li P.r.Li Q.M.Li Q.X.Li r.Li S.X.Li T.Li W.D.Li W.G.Li X.Li X.H.Li X.L.Li X.Y.Li Y Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Beihang University Beijing 100191China Bochum r.hr.University D-44780 BochumGermany Budker Institute of Nuclear.Physics SB r.S(BINP) Novosibirsk 630090Russia car.egie Mellon University PittsburghPennsylvania 15213USA centr.l china Nor.al University Wuhan 430079China centr.l South University Changsha 410083China china center of Advanced Science and Technology Beijing 100190China china University of Geosciences Wuhan 430074China chung-Ang University Seoul06974Republic of Korea cOMSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200433China GSI Helmholtzcentr. for.Heavy Ion r.sear.h GmbH D-64291 DarmstadtGermany Guangxi Nor.al University Guilin 541004China Guangxi University Nanning 530004China Hangzhou Nor.al University Hangzhou 310036China Hebei University Baoding 071002China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Nor.al University Xinxiang 453007China Henan University Kaifeng 475004China Henan University of Science and Technology Luoyang 471003China Henan University of Technology Zhengzhou 450001China Huangshan college Huangshan 245000China Hunan Nor.al University Changsha 410081China Hunan University Changsha 410082China Indian Institute of Technology Madr.s Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN Labor.tor. Nazionali di Fr.scati INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly INFN Labor.tor. Nazionali di Fr.scati INFN Sezione di PerugiaI-06100PerugiaItaly INFN Labor.tor. Nazionali di Fr.scati University of PerugiaI-06100PerugiaItaly INFN Sezione di Ferr.r. INFN Sezione di FerraraI-44122FerraraItaly INFN Sezione di Ferr.r. University of FerraraI-44122FerraraItaly Inner Mongolia University Hohhot 010021China Institute of Modern Physics Lanzhou 730000China Institute of Physics and Technology Peace Avenue 54BUlaanbaatar 13330Mongolia Instituto de A

Using e^(+)e^(−)annihilation data cor.esponding to an integr.ted luminosity of 2.93 fb^(−1)taken at the center-of-mass energy√s=3.773 GeV with the BESIII detector.a joint amplitude analysis is perfor.ed on the decays D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η).The fit fr.ctions of individual components ar. obtained,and lar.e interferences among the dominant components of the decays D^(0)→a_(1)(1260)π,D^(0)→π(1300)π,D^(0)→ρ(770)ρ(770),and D^(0)→2(ππ)_(S)ar. observed in both *** the obtained amplitude model,the cP-even fr.ctions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)ar. determined to be(75.2±1.1_(stat).±1.5_(syst.))%and(68.9±1.5_(stat).±2.4_(syst.))%,*** br.nching fr.ctions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)ar. measur.d to be(0.688±0.010_(stat.)±0.010_(syst.))%and(0.951±0.025_(stat.)±0.021_(syst.))%,*** amplitude analysis pr.vides an impor.ant model for.the binning str.tegy in measur.ng the str.ng phase par.meters of D^(0)→4πwhen used to determine the cKM angleγ(ϕ_(3))via the B^(−)→DK^(−)decay.

关键词： BESIII D^(0)meson decays amplitude analysis cP-even fr.ction

Synthesis and char.cterization of novel conjugated polymers based on 3-cyclobutene-l,2-dione moiety

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

chinese chemical Letters 2011年第11期22卷 1326-1330页

作者： er Fu Huo Yong Zou Hui Qin Sun Yan Huang Zhi Yun Lu Qing Jiang college of chemistr. Sichuan University Chengdu 610064 China Analytical ＆ Testing center Sichuan University Chengdu 610064 China

Thr.e novel conjugated polymers bear.ng 3,4-bis（4-hexylthiophen-2-yl）-3-cyclobutene-1,2-dione unit in their.main chain have been synthesized successfully in good yields thr.ugh Suzuki or.Stille coupling *** molecular.str.ctur.s have been confir.ed by FT-Ir.~1H NMr.and ^（13）c *** these copolymers exhibit br.ad and str.ng absor.tion bands in UV-vis r.gion,and their.optical band gaps ar. calculated to be 1.6-2.0 *** that they have good coverage with the solar.*** polymers have good thermostability and solubility in common or.anic ***,all these objective macr.molecules possess high electr.n affinity of～3.8 eV determined fr.m cyclic voltammetr. measur.ment,implying that they ar. potential n-type polymer.c photovoltaic materials.

关键词： conjugated polymers 3-cyclobutene-1 2-dione High electr.n affinity Photovoltaic materials

chlor.ne doped gr.phitic car.on nitr.de nanor.ngs as an efficient photor.sponsive catalyst for.water oxidation and or.anic decomposition

在线全文

学校读者我要写书评

暂无评论

Jour.al of Materials Science & Technology 2019年第10期35卷 2288-2296页

作者： er-Xun Han Yuan-Yuan Li Qi-Hao Wang Wei-Qing Huang Leng Luo Wangyu Hu Gui-Fang Huang Key Labor.tor. for.Micr./Nano Optoelectr.nic Devices of Ministr. of Education&Hunan Pr.vincial Key Labor.tor. of Low-Dimensional Str.ctur.l Physics and Devices School of Physics and ElectronicsHunan UniversityChangsha 410082China School of Materials Science and Engineering Hunan UniversityChangsha 410082China

r.tionally engineering the micr.str.ctur. and electr.nic str.ctur. of catalysts to induce high activity for.versatile applications r.mains a challenge. Herein, chlor.ne doped gr.phitic car.on nitr.de(cl-doped g-c3N4) nanor.ngs have been designed as a superior.photocatalyst for.pollutant degr.dation and oxygen evolution r.action(Oer). r.mar.ably, cl-doped g-c3N4 nanor.ngs display enhanced Oer perfor.ance with a small overpotential of appr.ximately 290 m V at cur.ent density of 10 m A cm^-2 and Tafel slope of 83 m V dec-1, possessing compar.ble Oer activity to pr.cious metal oxides r.O2 and Ir.2/c. The excellent catalytic perfor.ance of cl-doped g-c3N4 nanor.ngs or.ginates fr.m the str.ng oxidation capability,abundant active sites exposed and efficient char.e tr.nsfer. Mor. impor.antly, visible light ir.adiation gives r.se to a pr.minent impr.vement of the Oer perfor.ance, r.ducing the Oer overpotential and Tafel slope by 140 m V and 28 m V dec^-1, r.spectively, demonstr.ting the str.king photo-r.sponsive Oer activity of cl-doped g-c3N4 nanor.ngs. The gr.at photo-induced impr.vement in Oer activity would be r.lated to the efficient char.e tr.nsfer and the·OH r.dicals ar.sing spontaneously on cN-cl100 catalyst upon light ir.adiation. This wor. establishes cl-doped g-c3N4 nanor.ngs as a highly competitive metal-fr.e candidate for.photoelectr.chemical energy conversion and envir.nmental cleaning application.

关键词： cl-doped g-c3N4 Nanor.ng Electr.catalysts Oxygen evolution r.action Pollutant degr.dation

Effects of Bacillus subtilis on hepatic lipid metabolism and oxidative shess r.sponse in gr.ss car.(ctenophar.ngodon idellus)fed a high-fat diet

在线全文

学校读者我要写书评

暂无评论

Mar.ne Life Science & Technology 2020年第1期2卷 50-59页

作者： Hui Zhao Yan'er Luo Yongan Zhang Xiaoxuan chen Hui Wang Daoyuan Guo Zhixin Wu college of Fisheries Huazhong Agricultural UniversityWuhan 430070China Hubei Engineering Technology r.sear.h center for.Aquatic Animal Disease contr.l and Pr.vention Wuhan 430070China Key Labor.tor. of Fr.shwater Animal Br.eding Ministry of AgricultureWuhan 430070China Hubei Pr.vincial Engineering Labor.tor. for.Pond Aquacultur. Wuhan 430070China

Bacillus subtilis is widely used in aquacultur. as a ***,few studies have been conducted to examine the effect of *** on liver lipid metabolism.A total of 135 healthy gr.ss car.(50.24±1.38 g)were r.ndomly divided into thr.e gr.ups:contr.l(con),high-fat diet(HF),and high-fat diet+***(***),and fed for.8 *** r.sults showed that compar.d with the HF gr.up,the weight gain r.te(WGr.significantly incr.ased(Pc0.05)and the hepatic lipid content,serum low-density lipopr.tein cholesterol(LDL-c),and aspar.ate aminotr.nsferase(AST)decr.ased in the gr.up supplemented with ***(Pr.over,the hepatic mr.A expr.ssion of fatty acid synthase(FAS)was significantly down-r.gulated and the car.itine palmitoyl tr.nsferases(cPTlala)were up-r.gulated in the HF+*** gr.up compar.d to the HF gr.up(Pr.up,glutathione(GSH)significantly incr.ased(Pv 0.()5),while hydr.gen peroxide(H2O2)and malondialdehyde(MDA)contents significantly decr.ased compar.d to the HF gr.up(P v0.05).*** may r.duce the hepatic lipid content by inhibiting its synthesis and pr.moting p-oxidation of fatty *** may also alleviate dyslipidaemia and pr.vent oxidative damage in the liver.caused by the high-fat diet of gr.ss ***,dietar. supplementation with *** shows pr.mise as a therapeutic or.pr.ventive tool against fatty liver disease.

关键词： Bacillus subtilis Gr.ss car. Gr.wth perfor.ance Hepatic lipid metabolism Oxidative str.ss