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a.mond diversity a.d homozygosity define structure, kinship, inbreeding, a.d linka.e disequilibrium in cultiva.ed germpla.m, a.d revea. genomic a.socia.ions with nut a.d seed weight

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Horticulture Resea.ch 2021年第1期8卷 223-234页

作者： Stefa.o Pa.a. Chia.a.Delvento Rosa.Ma.zeo Fra.cesca.Riccia.di Pa.qua.e Loscia.e Lilia.a.Ga.ta.Nunzio D’a.ostino Fra.cesca.Ta.a.to Ra.uel sanchez-perez Luigi Riccia.di Concetta.Lotti Depa.tment of Soil Plant and Food ScienceUniversity of Bari Aldo MoroVia Amendola 165/ABari 70126Italy Institute of Biomedica. Technologies National Research Council(CNR)Via Amendola 122/DBari 70126Italy Depa.tment of the Sciences of a.riculture Food and EnvironmentUniversity of FoggiaVia Napoli 25Foggia 71100Italy Council for a.ricultura. Resea.ch a.d Economics-Resea.ch Centre for a.riculture a.d Environment(CREa.a.) Bari 70125Italy Depa.tment of a.ricultura. Sciences University of Naples Federico IIPortici 80055Italy Institute of Biosciences a.d Bioresources National Research Council of ItalyPortici 80055Italy CEBa.-CSIC.Ca.pus Universita.io de Espina.do 30100 EspinardoSpain

a.mond[Prunus dulcis Miller(***)]is the ma.n tree nut species ***,genotyping-by-sequencing(GBS)wa. a.plied to 149 a.mond cultiva.s from the ex situ collections of the Ita.ia. Council for a.ricultura. Resea.ch(CREa.a.d the Spa.ish Na.iona. Resea.ch Council(CSIC),lea.ing to the detection of 93,119 single-nucleotide polymorphisms(SNPs).The study of popula.ion structure outlined four distinct genetic groups a.d highlighted diversifica.ion between the Mediterra.ea. a.d Ca.ifornia. gene *** on SNP diversity a.d runs of homozygosity(ROHs)a.lowed the definition of kinship,inbreeding,a.d linka.e disequilibrium(LD)deca. in a.mond cultiva.ed ***-yea. phenotypic observa.ions,ga.hered on 98 cultiva.s of the CREa.collection,were used to perform a.genome-wide a.socia.ion study(GWa.)a.d,for the first time in a.crop species,homozygosity ma.ping(HM),resulting in the identifica.ion of genomic a.socia.ions with nut,shell,a.d seed *** GWa. a.d HM suggested tha. loci controlling nut a.d seed weight a.e mostly ***,this study provides insights on the a.mond cultiva.ion history a.d delivers informa.ion of ma.or interest for a.mond genetics a.d *** a.broa.er perspective,our results encoura.e the use of ROHs in crop science to estima.e inbreeding,choose pa.enta. combina.ions minimizing the risk of inbreeding depression,a.d identify genomic footprints of selection for specific tra.ts.

关键词： linka.e structure Ita.ia.

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Optimiza.ion of Resource in the Industry of Construction

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Journa. of Civil Engineering a.d a.chitecture 2014年第9期8卷 1145-1150页

作者： Fra.cisco Ja.ier Gutierrez Ga.cia.Pedro perez Dia. Pedro sanchez Luis Depa.tment of Construction Engineering University of La Laguna Tenerife 38204 Spain

Time a.d cost a.e two of the most importa.t fa.tors to consider in ea.h construction project. In order to ma.imize performa.ce, both the client a.d the contra.tor will work to optimize both the dura.ion of the project a.d its cost. We show a.model of linea. entire mixed progra.ming to solve the considered problem. The a.m is to minimize the project tota. time, by mea.s of the a.signment of equipments of work to the different production lines of the a.tivities to rea.izing. The funda.enta. beginning is to support the sa.e production (ra.e of production in meters/da. of the a.tivity in view of the equipment of work) for the different equipments to a.hieve the ma.imum efficiency in ea.h period of time. With the limited a.a.la.ility of resources, the work must be continuous a.d the period of time between opera.ions a.d fina. must be kept. However, this pa.er a.so presents the bibliogra.hica. study on methodologies of the optimiza.ion of construction processes in response to the two objectives: time a.d cost. This will consider the use of meta.heuristic techniques, such a. popula.ion ba.ed a.gorithms.

关键词：产业优化资源建设持续时间施工项目混合编程生产速度最大效率施工过程

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Urina.y Excretion of microRNa. in Young Fa.ry Disea.e Pa.ients with Mild or a.sent Nephropa.hy

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Open Journa. of Nephrology 2018年第3期8卷 71-83页

作者： Seba.tián Ja.rretche Gra.iela.Venera.Norberto a.tongiova.ni Ferna.do Perretta.Germán R. perez School of Medicine Instituto Universitario Italiano de Rosario Rosario Argentina Los Ma.a.tia.es Neurosciences Center Rosario Argentina. Center for Infusion a.d Study of Lysosoma. Disea.es Instituto de Nefrología de Pergamino Pergamino Argentina Intensive Ca.e Unit Hospital Dr. Enrique Erill Belen de Escobar Argentina School of Biochemica. a.d Pha.ma.eutica. Sciences Nacional University of Rosario Rosario Argentina Ga.ma.a. Grupo Ga.ma Rosario Argentina

Fa.ry disea.e (FD) clinica. ma.ifesta.ions often sta.t in childhood. a.ong the FD complica.ions, rena. fa.lure ca.ses significa.t morbidity a.d morta.ity. Ea.ly dia.nosis a.d trea.ment of FD nephropa.hy in children ma. be critica. to preserve rena. function. In proteinuric progressive nephropa.hies it ha. been described tha. pro-fibrotic miR-21, miR-192, a.d miR-433 fa.ilies a.e a.tiva.ed a.d tha. a.ti-fibrotic miR-29 a.d miR-200 fa.ilies a.e inhibited. Objective: a.a.yze urina.y excretion of microRNa. rela.ed to rena. fibrosis in FD pa.ients with mild or a.sent nephropa.hy. Pa.ients with confirmed dia.nosis of FD under 18 yea.s of a.e were compa.ed with hea.thy subjects. Pa.ients were cla.sified into two groups: 1) Pa.ients with urina.y excretion profile of microRNa. indica.ive of rena. fibrosis;a.d 2) Pa.ients with urina.y excretion profile of microRNa. not indica.ive of rena. fibrosis. Results: 9 hea.thy subjects were enrolled in the study (18.66 ± 13.43 yea.s), 4 ma.es a.d 5 fema.es. a.l of them presented norma. eFGR without pa.hologica. a.buminuria. FD popula.ion: 12 pa.ients (10.33 ± 3.93 yea.s) were studied, 5 ma.es a.d 7 fema.es. Pa.ients presented 2 different genotypes: L415P (6 pa.ients) a.d E398X (6 pa.ients). The urina.y excretion profile of microRNa. indica.ive of rena. fibrosis wa. present in 4 pa.ients (2 with L415P genotype a.d 2 with E398X genotype), a.l of them with a.decrea.ed of miR-29 a.d/or miR-200. No pa.ient presented increa.ed miR-21, miR-192 a.d/or miR-433. Decrea.ed α-ga.-a.a.tivity wa. the only va.ia.le a.socia.ed with sta.istica. significa.ce (p ≤ 0.01) to urina.y excretion profile of microRNa.indica.ive of rena. fibrosis. Conclusions: Young FD pa.ients with cla.sica. muta.ions of GLa.gene a.d mild or a.sent nephropa.hy could present a.profile of urina.y excretion of microRNa. indica.ive of rena. fibrosis a.socia.ed with decrea.ed α-ga.-a.a.tivity independently of the other va.ia.les. Our findings could suggest a.regula.ion of microRNa.

关键词： Fa.ry Nephropa.hy Bioma.kers Urina.y microRNA Rena. Fibrosis Ea.ly Dia.nosis

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Construct a.d Convergent Va.idity of the OIS-Ga.cia.（Optimist Intera.tive Style） Sca.es in a.Mexica. Popula.ion

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Psychology Resea.ch 2013年第9期3卷 518-528页

作者： Cirilo H. Ga.cia.Hector L. Dia. a.noldo Tellez Fuensa.ta.Lopez Jua. Ma.tinez Lorenzo sanchez enrique Ga.cia Universida. a.t6noma.de Nuevo Le6n Monterrey M6xico The University of Texa.-Pa. a.erica. Edinburg USA Universida. a.tonoma.de Nuevo Leon Monterrey Mexico

This is a.report of the va.ida.ion process of two sca.es tha. mea.ure the OIS-Ga.cia.(optimist intera.tive style). a. a.tempt wa. ma.e to esta.lish construct a.d convergent va.idity for these two sca.es. Towa.ds this end, we relied on the Spa.ish version of the LOT-R (life orienta.ion test-revised). Pa.ticipa.ts were 350 rela.ives of a.ca.cer pa.ient with a.mea. a.e of 39.87 yea.s (SD = 14.88) a.d a. a.e ra.ge going from 15 to 79 yea.s. Ea.h of the new versions of the OIS1-Ga.cia.a.d OIS2-Ga.cia.comprised 10 items. The Chronba.h a.pha.interna. consistency coefficients were 0.701 for the OIS1 a.d 0.633 for the OIS2. The Spea.ma. correla.ion coefficient a.ong these two tests wa. 0.438, the correla.ion a.ong LOT-R a.d OIS1-Ga.cia.wa. 0.382, a.d the correla.ion a.ong LOT-R a.d OIS2-Ga.cia.wa. 0.468. a. a.result, we were a.le to pa.tia.ly va.ida.e both versions of the OIS-Ga.cia.test. These findings serve a. encoura.ement to develop more cultura.ly sensitive a.d a.propria.e mea.urement instruments for specific cultures or popula.ions.

关键词：西亚收敛墨西哥人口风格定位测试验证过程平均年龄

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White Mulberry （Morus a.ba. Folia.e a. a.Feeding Supplement for Growing Ca.ves

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Journa. of a.ricultura. Science a.d Technology(a. 2016年第1期6卷 59-63页

作者： a.a.ia.Ca.rera.Nunez Ilia.a.Del Ca.men Da.iel Renteria.Miguel a.gel La.moglia.Villa.omez Cesa. enrique Ma.tinez sanchez Sa.a.a.da.a.a.con Pulido Rebeca.Roja.-Ronquillo School of Biologica. a.d a.ricultura. Science University of Veracruz Tuxpan Veracruz 92860 Mexico

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Determina.ion of Epibionts of the Ma.ine Turtle Lepidochelys Ofiva.ea.（Eschscholtz, 1829） Nesting in Ceuta.Bea.h, Sina.oa. Mexico

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Journa. of a.ricultura. Science a.d Technology(B) 2012年第11期2卷 1190-1194页

作者： Ingma. Sosa.Comejo Dulce Ita.ivi Monta.o-Va.dez Ma.cos Bucio-Pa.heco Ferna.do Enciso-Sa.a.ho Jorge Guillermo sanchez-Za.ueta.Estela.Fierros-perez Escuela.de Biologla Universidad Autdenoma de Sinaloa Culiacfn Rosales Sinaloa CP 80030 Mexico Fa.ulta. de Ciencia. del Ma. Universidad Autenoma de Sinaloa. Mazatl6n Sinaloa Mexico

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Fa.tors Tha. Motiva.e Undergra.ua.e Students： a. a.a.ysis a. a.University in Mexico

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Journa. of Modern a.counting a.d a.diting 2016年第1期12卷 52-59页

作者： Selene Viridia.a.perez Ra.irez Pa.la.Ponce La.a.o Silvia.Ca.tuja.o Escoba. Crisoforo a.va.ez Viola.te Roque Lopez Ta.a.go enrique Pineda.Figueroa.Ma. Isa.el Mora.es Ra.gel a.tonomous University of Morelos Sta.e Morelos Mexico Mexica. Dista.ce Educa.ion University Mexico

The objective of this resea.ch wa. to a.a.yze (or cha.a.terize) wha. motiva.iona. fa.tors a.e involved in the continuity of the a.a.emic development of students in the Gra.ua.e School of Jojutla. The study is qua.tita.ive, descriptive, a.d tra.sversa.. The popula.ion is composed of 346 students who entered college in 2014. a.sa.ple of 52 students out of this popula.ion wa. selected, from the ma.ors of Business Ma.a.ement, a.counting, La., Environmenta. Sciences, Psychology, a.d Computer Science. The da.a.collection instrument wa. developed by Esquivel a.d a.jona.(2003), which mea.ured the dimensions of security, a.filia.ion or a.fection, self-fulfillment, a.hievement, power, recognition, a.d knowledge. The results showed tha. 72.7% of new students pla.e a.very high va.ue on the knowledge dimension: lea.ning new things, improve study skills, do resea.ch, better overa.l job tra.ning, a.d interest in lea.ning. However, in other dimensions, such a. a.filia.ion or a.fection, the percenta.e given by students is 9.1%. While the study consists of a.sma.l sa.ple, the results provide importa.t informa.ion on motiva.ion a. a.fa.tor tha. must be considered a.d eva.ua.ed throughout the a.a.emic record of the student in order to prevent dropouts a.d increa.e termina. efficiency.

关键词：会计审计方法技术

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Molecula. isola.ion a.d identifica.ion of Mycoba.terium a.ium *** in Didelphis virginia.a.from Hida.go,Mexico

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a.ia. Pa.ific Journa. of Tropica. Medicine 2020年第3期13卷 131-136页

作者： Na.lely Rivero-perez Jua. Oca.po-López Benja.ín Va.la.a.es-Ca.ra.za.Fa.ián R.Gómez de a.da.Fra.cisco J.Pena.Jiménez Victor M.Ma.tínez Juárez a.ma.do Peláez a.ero Jose I.Ola.e Leyva.Deya.ira.Ojeda.Ra.írez a.ria. Za.a.oza.Ba.tida a.ea.a.a.émica.de Medicina.Veterina.ia.y Zootecnia Instituto de Ciencias AgropecuariaUniversidad Autónoma del Estado de HidalgoAv.Universidad Km 1Ex-Hda.de AquetzalpaC.P.43600 TulancingoHidalgoMéxico Centro de Investiga.ión y Estudios a.a.za.os en Sa.ud a.ima. Facultad de Medicina Veterinaria y ZootecniaUniversidad Autónoma del Estado de MéxicoKm 15.5 Carretera Panamericana Toluca-AtlacomulcoC.P.50200 TolucaEstado de MéxicoMéxico Centro Universita.io del Sur/División de Ciencia. de la.Sa.ud/Depa.ta.ento de Ciencia. Clínica./Hospita. Veterina.io CUSUR Universida. de Gua.a.a.a.a Av.Enrique Arreola Silva No.883colonia centro C.P.49000Ciudad GuzmánJaliscoMéxico

Objective:To isola.e a.d identify the exa.t species of the genus Mycoba.terium from Didelphis(D.)virginia.a.a.d the direct implica.ions of this ba.terium to public hea.th a.d veterina.y ***:Thirty-one *** were ca.tured a.d necropsied in Hida.go,*** sa.ples were collected to culture mycoba.teria.present a.d exa.ine individua. specimens’*** identifica.ion wa. obta.ned through the a.plica.ion of a.plifica.ion a.d sequencing of 16S rDNa.***:Three stra.ns were isola.ed a.d identified a. Mycoba.terium(M.)a.ium *** by utilizing *** complexspecific *** lesions were observed in the subpleura. zone(gra.uloma.gra.eⅡ)a.d bronchia.(gra.uloma.gra.eⅠ)of the lungs of *** with positive ***:Three stra.ns of *** ***,from lung tissue sa.ples of *** were *** subspecies of *** ha. importa.t implica.ions in public hea.th a.d veterina.y medicine.

关键词： Didelphis virginia.a Mycoba.terium a.ium complex Mycoba.terium a.ium subsp.hominissuis Public hea.th

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Effectiveness a.d sa.ety of first-genera.ion protea.e inhibitors in clinica. pra.tice:Hepa.itis C virus pa.ients with a.va.ced fibrosis

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World Journa. of Ga.troenterology 2015年第30期21卷 9163-9174页

作者： Ja.ier Sa.meron Ca.men Vina.xa.Ruben Berenguer Jua. Ma.uel Pa.ca.io Jua. Jose sanchez Rua.o Miguel a.gel Serra.a.a.Gila.Moises Dia.o Ma.uel Romero-Gomez Jose Ma.ia.Na.a.ro Mila.ros Testilla.o Conra.o Ferna.dez Dolores Espinosa.Isa.el Ca.mona.Jose a.tonio Pons Fra.cisco Jorquera.Fra.cisco Ja.ier Rodriguez Ra.on perez Jose Luis Montero Ra.a.l Gra.a.os Miguel Ferna.dez a.a.Belen Ma.tin Pa.oma.Munoz de Rueda.Rosa.Quiles CIBERehd Instituto de Salud Carlos Ⅲ28029 MadridSpain Unit for Clinica. Ma.a.ement of Digestive Disea.es Complejo Hospitalario Universitario de Granada Instituto de Investiga.ion Biosa.ita.ia.de Gra.a.a University Hospita. Politecnico La.Fe Unit for Clinica. Ma.a.ement of Digestive Disea.es University Hospital Virgen Del Rocio Hospita. Toledo University Clinic Hospita. of Va.encia University Genera. Hospita. of Va.encia Unit for Clinica. Ma.a.ement of Digestive Disea.es University Hospital Nuestra Senora de Valme Depa.tment of Ga.troenterology a.d Hepa.ology a.encia.Sa.ita.ia.Costa.del Sol University Hospita. Cruces Ga.troenterology Unit University Hospital Fundacion Alcorcon University Hospita. Virgen Ma.a.ena University Hospita. Virgen de la.a.rixa.a Hospita. of Leon University Genera. Hospita. Reina.Sofia Depa.tment Ga.troenterology a.d Hepa.ology University Hospital Central de Asturias University Hospita. Reina.Sofia University Hospita. De Gra. Ca.a.ia.Dr. Negrin Hospita. Sa. Pedro de a.ca.ta.a

a.M:To eva.ua.es the effectiveness a.d sa.ety of the first genera.ion,NS3/4a.protea.e inhibitors(PIs) in clinica. pra.tice a.a.nst chronic C virus,especia.ly in pa.ients with a.va.ced fibrosis. METHODS:Prospective study a.d non-experimenta. a.a.ysis of a.multicentre cohort of 38 Spa.ish hospita.s tha. includes pa.ients with chronic hepa.itis C genotype 1,trea.ment-na.ve(TN) or trea.ment-experienced(TE),who underwent triple thera.y with the first genera.ion NS3/4a.protea.e inhibitors,boceprevir(BOC) a.d tela.revir(TVR),in combina.ion with pegyla.ed interferon a.d riba.irin. The pa.ients were trea.ment in routine pra.tice settings. Da.a.on the study popula.ion a.d on a.verse clinica. a.d virologic effects were compiled during the trea.ment period a.d during follow ***:One thousa.d a.d fifty seven pa.ients were included,405(38%) were trea.ed with BOC a.d 652(62%) with TVR. Of this tota.,30%(n = 319) were TN a.d the rema.ning were TE:28%(n = 298) rela.sers,12%(n = 123) pa.tia. responders(PR),25%(n = 260) null-responders(NR) a.d for 5%(n = 57) with prior response unknown. The ra.e of susta.ned virologic response(SVR) by intention-to-trea.ment(ITT) wa. grea.er in those trea.ed with TVR(65%) tha. in those trea.ed with BOC(52%)(P a. by modified intention-to-trea.ment(m ITT) no were found significa.t differences. By degree of fibrosis,56% of pa.ients were F4 a.d the highest SVR ra.es were recorded in the non-F4 pa.ients,both TN a.d TE. In the a.a.ysis by groups,the TN pa.ients trea.ed with TVR by ITT showed a.higher SVR(P = 0.005). However,by m ITT there were no significa.t differences between BOC a.d TVR. In the multiva.ia.e a.a.ysis by m ITT,the significa.t SVR fa.tors were rela.sers,IL28 B CC a.d non-F4; the type of trea.ment(BOC or TVR) wa. not significa.t. The lowest SVR va.ues were presented by the F4-NR pa.ients,trea.ed with BOC(46%) or with TVR(45%). 28% of the pa.ients interrupted the trea.ment,ma.nly by non-vira. response(51%):this outcome wa.

关键词： Hepa.itis C Boceprevir Tela.revir First-genera.ion protea.e inhibitors a.va.ced fibrosis

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Compa.a.ive study of brea.t ca.cer in Mexica. a.d Mexica.-a.erica. women

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Hea.th 2010年第9期2卷 1040-1048页

作者： Ma.ia.Elena.Ma.tinez Luis enrique Gutierrez-Milla. Melissa.Bondy a.ria. Da.eri-Na.a.ro Ma.ia.Mercedes Meza.Montenegro Iva. a.duro-Corona.Ma.Isa.el a.a.buro-Rubio Luz Ma.ia.a.ria.a.Ba.dera.-Pena.Jose a.elfo Ba.ra.a.-Ruiz a.ena. Brewster Gra.iela.Ca.re-Juvera.Jua. Ma.uel Ca.tro-Cerva.tes Ma.io a.berto Cha.ez Za.udio Giova.na.Cruz a.icia.Del Toro-a.reola.Ma.y EEdgerton Ma.ia.Rosa.Flores-Ma.quez Ra.on a.tonio Fra.co-Topete Helga.Ga.cia.Susa. a.drea.Gutierrez-Rubio Ka.in Ha.n Luz Ma.ga.ita.Jimenez-perez Ia. KKomena.a.Zoila.a.eli Lopez Buja.da.Dihui Lu Gilberto Morga.-Villela.Ja.es LMurra. Jesse NNodora.a.tonio Oceguera.Villa.ueva.Miguel a.gel Ortiz Ma.tinez La.ra.perez Michel a.tonio Quintero-Ra.os a.segul Sa.in Jeong Yun Shim Ma.reen Stewa.t Gonza.o Va.quez-Ca.a.ho Betsy Wertheim Ra.hel Zenuk Pa.ricia.Thompson a.izona.Ca.cer Center a.d Mel a.d Enid Zuckerma. College of Public Hea.th University of ArizonaTucsonUSA Depa.ta.ento de Investiga.iones Cientifica. y Tecnologica. Universidad de SonoraHermosilloMexico University of Texa. M.D.a.derson Ca.cer Center HoustonUSA Depa.ta.ento de Fisiologia Centro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajaraMexico Instituto Tecnologico de Sonora Ciudad ObregónMexico Instituto Mexica.o del Seguro Socia. HermosilloMexico Instituto Mexica.o del Seguro Socia. CMNOGuadalajaraJalisco Centro de Investiga.ion en a.imenta.ion y Desa.rollo HermosilloMexico Instituto Mexica.o del Seguro Socia. Ciudad ObregonMexico OPD Hospita. Civil de Gua.a.a.a.a GuadalajaraMexico Depa.ta.ento de Sa.ud Publica Centro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajaraMexico Ma.icopa.Medica. Center Department of SurgeryPhoenixUSA University of North Ca.olina Lineberger Cancer CenterChapel HillUSA a.izona.Ca.cer Center a.d Depa.tment of Fa.ily a.d Community Medicine University of ArizonaTucsonUSA Instituto Ja.isciense de Ca.cerologia GuadalajaraMexico

Brea.t ca.cer is the number one ca.se of ca.- cer dea.hs a.ong Hispa.ic women in the United Sta.es, a.d in Mexico, it recently beca.e the prima.y ca.se of ca.cer dea.hs. This ma.ign- na.cy represents a.poorly understood a.d un- derstudied disea.e in Hispa.ic women. The ELLa.Bina.iona. Brea.t Ca.cer Study wa. es- ta.lished in 2006 a. a.multi-center study to a.- sess pa.terns of brea.t tumor ma.kers, clinica. cha.a.teristics, a.d their risk fa.tors in women of Mexica. descent. We describe the design a.d implementa.ion of the ELLa.Study a.d provide a.risk fa.tor compa.ison between women in the U.S. a.d those in Mexico ba.ed on a.sa.ple of 765 pa.ients (364 in the U.S. a.d 401 in Mexico). Compa.ed to women in Mexico, U.S. women ha. significa.tly (p a.ity (3.2 vs. 3.9 mea. live births) a.d brea.tfeeding ra.es (57.5% vs. 80.5%), higher use of ora. contra.eptives (60.7% vs. 50.1%) a.d hormone repla.ement thera.y (23.3% vs. 7.6%), a.d higher fa.ily history of brea.t ca.cer (15.7% vs. 9.0%). Re- sults show tha. differences in brea.t ca.cer risk fa.tor pa.terns exist between Mexico a.d U.S. women. We provide lessons lea.ned from the conduct of our study. Bina.iona. studies a.e a. importa.t step in understa.ding disea.e pa.- terns a.d etiology for women in both countries.

关键词： Bina.iona. Study Brea.t Ca.cer Hispa.ics Mexico United Sta.es

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