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The complex role of physical exercise and reactive oxygen species on brain

Journal of Sport and Health Science 2013年第2期2卷 87-93页

作者： Zsolt Radak Orsolya Marton eniko nagy Erika Koltai Sataro Goto Institute of Sport Science Faculty of Physical Education and Sport ScienceSemmelweis University Department of Exercise Physiology School of Health and Sport ScienceJuntendo University

Reactive oxygen species （ROS） are continuously generated during aerobic metabolism and at moderate level. They play a role in redox signaling, but in significant concentration they cause oxidative damage and neurodegeneration. Because of the enhanced sensitivity of brain to ROS, it is especially important to maintain the normal redox state in different types of neuron cells. In last decade it became clear that regular exercise beneficially affects brain function, and can play an important preventive and therapeutic role in stroke, Alzheimer, and Parkinson diseases. The effects of exercise appear to be very complex and could include neurogenesis via neurotrophic factors, increased capillariszation, decreased oxidative damage, and increased proteolyfic degradation by proteasome and neprilysin. Data from our and other laboratories indicate that exercise-induced modulation of ROS levels plays a role in the protein content and expression of brain-derived neurotrophic factor, tyrosinerelated kinase B （TrkB）, and cAMP response element binding protein, resulting in better function and increased neurogenesis. Therefore, it appears that exercise-induced modulation of the redox state is an important means, by which exercise benefits brain function, increases the resistance against oxidative stress, facilitates recovery from oxidative stress, and attenuates age-associated decline in cognition.

关键词： Exercise Neurotrophins brain function Oxidative damage Oxidative stress

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Effect of silver-nanoparticles generated in poly(vinyl alcohol)membranes on ethanol dehydration via pervaporation

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Chinese Journal of Chemical Engineering 2019年第7期27卷 1595-1607页

作者： Asmaa Selim Andras Jozsef Toth Daniel Fozer eniko Haaz Nóra Valentínyi Tibor nagy Orsolya Keri Lászlo Péter Bakos Imre Miklós Szilágyi Peter Mizsey Department of Chemical and Environmental Process Engineering Budapest University of Technology and Economics1111 BudapestHungary Chemical Engineering Department National Research Centre12611 GizaEgypt Department of Inorganic and Analytical Chemistry Budapest University of Technology and Economics1111 BudapestHungary Department of Fine Chemicals and Environmental Technology University of Miskolc3515 MiskolcHungary

Pervaporation is an important membrane separation method of chemical *** this work,silver-nanoparticles-poly(vinyl alcohol)nanocomposite membranes(AgNPs-PVA)are produced for the sake of improving its potentials for pervaporation of ethanol–water mixture so that the usual opposite trend between membrane selectivity and permeation can be *** nanocomposite membranes are fabricated from an aqueous solution of poly(vinyl alcohol)with silver nanoparticles via the in-situ generation technique in the absence of any reducing *** generation of the nano size silver is measured by the UV–vis spectrum showing a single peak at 419 nm due to the plasmonic effect of silver *** nanocomposite AgNPs-PVA membranes are characterized using scanning electron microscope(SEM),Fourier-transform infrared(FT-IR)spectroscopy,X-ray diffraction and thermogravimetric analysis(TGA).The pervaporation tests of our new AgNPs-PVA membranes show good results since at a higher temperature and higher ethanol concentration in the feed,the prepared membranes are highly permeable for the water having stable selectivity values and therefore our membranes show better performance compared to that of the other PVA-based nanocomposite membranes.

关键词： Silver nanoparticle Poly(vinyl alcohol)nanocomposite membrane Hydrophilicity Swelling degree Pervaporation

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