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Autoimmune pancreatitis with atypical imaging findings that mimicked an endocrine tumor

World Journal of Gastroenterology 2010年第23期16卷 2954-2958页

作者： Cindy Neuzillet Céline Lepère Mostafa El Hajjam Laurent Palazzo Monique Fabre Hajer Turki Pascal Hammel Philippe Rougier emmanuel mitry Department of Digestive Surgery and Gastroenterology and Digestive Oncology Ambroise Paré Hospital9avenue Charles de Gaulle Radiology Unit Ambroise Paré Hospital9avenue Charles de Gaulle Medical off ice of Gastroenterology 30rue d'Astorg Pathology Unit Bicêtre Hospital78rue du Général Leclerc Department of Digestive Surgery and Gastroenterology PMADBeaujon Hospital100 boulevard du Général Leclerc EA 4340 Faculty of Medicine of West Paris University of Versailles Saint-Quentin9 boulevard d'Alembert

Autoimmune pancreatitis(AIP) is a rare cause of recurrent acute pancreatitis or chronic pancreatitis in middleaged patients,and is characterised by a marked infiltration of lymphocytes and plasma cells in pancreatic *** of focal forms can be diff icult as AIP may mimic pancreatic *** cases of AIP are *** report the case of a 15-yearold girl who had a focal AIP and associated cholangitis,with a very unusual vascularized mass that mimicked a pancreatic endocrine *** diagnosis was obtained by a pancreatic biopsy,thus avoiding surgical resection,and all the clinical,biological and radiological abnormalities resolved after steroid therapy with 6 mo of follow-up.

关键词： Pancreas Autoimmune pancreatitis Adolescent Endocrine tumor Biopsy

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Organ sparing to cure stage IV rectal cancer: A case report and review of literature

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World Journal of Gastrointestinal Surgery 2023年第11期15卷 2619-2626页

作者： Hélène Meillat Jonathan Garnier Anais Palen Jacques Ewald Cécile de Chaisemartin Marguerite Tyran emmanuel mitry Bernard Lelong Department of Digestive Surgical Oncology Institut Paoli CalmettesMarseille 13009France Department of Radiotherapy Institut Paoli CalmettesMarseille 13009France

BACKGROUND Rectal sparing is an option for some rectal cancers with complete or good response after chemoradiotherapy(CRT);however,it has never been evaluated in patients with *** assessed long-term outcomes of a rectal-sparing approach in a liver-first strategy for patients with rectal cancer with resectable liver *** SUMMARY We examined patients who underwent an organ-sparing approach for rectal cancer with synchronous liver metastases using a liver-first strategy during 2010-2015(n=8).Patients received primary chemotherapy and pelvic *** surgery was performed during the interval between CRT completion and rectal tumor *** and oncological characteristics and long-term outcomes were *** SUMMARY All patients underwent liver metastatic resection with curative *** R0 rate was 100%.Six and two patients underwent local excision and a watch-and-wait(WW)approach,*** patients had T3N1 tumors at diagnosis and had good clinical response after *** median survival time was 60(range,14-127)*** patients were disease free for 5,8,and 10 years after the *** patients developed metastatic recurrence in the liver(n=5)and/or lungs(n=2).Only one patient developed local recurrence concurrent with metastatic recurrence 24 mo after the WW *** patients died during *** The results suggest good local control in patients undergoing organ-sparing strategies for rectal cancer with synchronous liver *** trials are required to validate these data and identify good candidates for these strategies.

关键词： Colorectal cancer Liver metastasis Rectal sparing Pver-first strategy

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太空路由器

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科技纵览 2020年第2期 42-47页

作者： Mina mitry 不详

几十年来,发射一颗卫星的费用就是天文数字,这意味着只有政府机构和大型企业才能够承担如此艰巨的任务.但在最近约20年里,能够适应多种有效载荷的新型商用火箭设计大幅降低了发射费用,从2000年的每千克5.4万美元降至2018年的2720美元左... 详细信息

几十年来,发射一颗卫星的费用就是天文数字,这意味着只有政府机构和大型企业才能够承担如此艰巨的任务.但在最近约20年里,能够适应多种有效载荷的新型商用火箭设计大幅降低了发射费用,从2000年的每千克5.4万美元降至2018年的2720美元左右.这一趋势同样推动了私人卫星产业的繁荣.自2012年以来,发射进入近地轨道(LEO)的小型卫星(大致为重量在50千克以下的卫星)数量每年增长30%.

关键词：路由器卫星产业小型卫星发射费用近地轨道有效载荷 LEO

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奥沙利铂联合氟尿嘧啶二线治疗晚期胰腺癌:Ⅱ期临床试验结果

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世界核心医学期刊文摘（胃肠病学分册） 2006年第12期2卷 31-32页

作者： mitry E. DucreuxM. Ould-KaciM. 成虹 Service d'Hépato-Gastroentérologie et Oncologie Digestive CHU Amoroise Paré9avenue Charles de Gaulle92100 BoulogneFrance

Background-The efficacy and benefit of second-line chemotherapy in advanced pancreatic adenocarcinoma has never been demonstrated although it is regularly *** and methods-A randomized phase II study evaluating oxaliplatin alone(OXA) ,infusional 5-fluorouracil alone(5-FU) and an oxaliplatin/infusional 5-FU combination(OXFU) in untreated advanced pancreatic adenocarcinoma has been *** this trial,a second-line treatment with the OXFU regimen(OXA 130 mg/m2 2-h intravenous(i.v.) infusion combined with 5-FU(1000 mg/m2/day,continuous i.v.,days 1-4) ,every 3 weeks) was offered to patients progressing after single agent ***-Eighteen out of 32 patients(12 males,median age 57 years) treated in the single agent arms received the OXFU combination in second-line *** performance status was at least 2 in 61% of the *** was no objective response and 3 patients(17%) had a disease *** time to progression from the start of second-line treatment was 0.9 *** overall survival was 4.9 months from the start of front-line therapy and 1.3 months from the start of second-line ***-The results of this trial bring arguments to support a modest value of second-line chemotherapy for advanced pancreatic adenocarcinoma.

关键词：晚期胰腺癌尿嘧啶二线治疗 Ⅱ期临床试验联合方案随机临床研究存活期

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胰腺转移癌:对22例患者的多中心研究

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世界核心医学期刊文摘（胃肠病学分册） 2005年第3期1卷 29-30页

作者： Moussa A. mitry E. Hammel P. G. Lesur 赵天智 Serv. Hepato Gastroenterol./O. D. H.opital Ambroise Paré 92104 Boulogne Billancourt France

Aims of the study To evaluate the diagnosis, treatment and outcome of patients with pancreatic metastases. Patients and methods We retrospectively reviewed the records of patients with pancreatic metastasis managed in the Paris area between 1990 and 2000. Results The series analyzed included 22 patients, 10 men and 12 women, mean age 61 years (range: 35-76). The primary tumors were renal cell carcinoma (N = 10), colorectal cancer (N = 4), lung cancer (N = 4), breast cancer (N = 2), cutaneous melanoma (N = 1) and ileal carcinoid (N = 1). The mean interval between primary treatment and presentation was 73.5 months (range: 2-151). Diagnosis was established because of clinical symptoms (N = 15) or during surveillance (N = 7). Computed tomography (N = 19) and endoscopie ultrasound (EUS) (N= 18) mainly showed solitary and hypodense/or hypoechoic masses. Histological diagnosis was obtained before surgery by EUS guided fine needle aspiration(N =6), ultra sound guided biopsy (N = 3) or duodenoscopy (N = 3). Among 10 patients with primary renal cell carcinoma, 7 were treated by surgery. Median global survival was 33 months. Median survival was 61 months in the event of surgical treatment and 20 months in the other patients (ns). Mean survival depended on the type of primary tumor, 61 months for renal cell carcinoma and 33 for colorectal cancer (P = 0.06). Conclusions Most pancreatic metastases develop from renal cell carcinoma and can occur several years after nephrectomy. Histological diagnosis is often obtained before surgery. Surgical resection must be discussed as it can allow long term survival.

关键词：肾细胞癌结直肠癌原发肿瘤平均生存期手术切除术外科手术患者组织学诊断平均间隔低回声肿块黑色素瘤

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