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Recent advances in the u.derstanding and management of chronic pancreatitis pain

Jou.nal of Pancreatology 2024年第1期7卷 35-44页

作者： Jessica Walker Olivia l.Babyok Jami l.Saloman Anna Evans Phillips Department of Internal Medicine University of Pittsburgh Medical CenterPittsburghPAUnited States Division of Gastroenterology Hepatology and NutritionDepartment of MedicineSchool of MedicineUniversity of PittsburghPittsburghPAUnited States Center for Pain Research Center for NeuroscienceSchool of MedicineUniversity of PittsburghPittsburghPAUnited States

Abdominal pain is the most common symptom of chronic pancreatitis(CP)and is often debilitating for patients and very difficu.t to *** date,there exists no cu.e for the *** strategies focu. on symptom management and on mitigation of disease progression by redu.ing toxin exposu.e and avoiding recu.rent inflammatory *** treatment protocols start with medical management followed by consideration of procedu.al or su.gical intervention on selected patients with severe and persistent *** incorporation of adju.ant therapies to treat comorbidities inclu.ing psychiatric disorders,exocrine pancreatic insu.ficiency,mineral bone disease,frailty,and malnu.rition,are in its early *** clinical stu.ies and animal models have been designed to improve investigation into the pathophysiology of CP pain,as well as to improve pain *** the array of tools available,many therapeu.ic options for the management of CP pain provide incomplete *** still remains mu.h to discover abou. the neu.al regu.ation of pancreas-related *** this review,we will discu.s research from the last 5 years that has provided new insights into novel methods of pain phenotyping and the pathophysiology of CP *** discoveries have led to improvements in patient selection for optimization of ou.comes for both medical and procedu.al management,and identification of potential fu.u.e therapies.

关键词： Central sensitization Chronic pancreatitis Pain phenotyping Peripheral sensitization

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Plastic deformation of a Zr-based bu.k metallic glass fabricated by selective laser melting

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Jou.nal of Materials Science & Technology 2021年第1期60卷 139-146页

作者： l.Deng K.Kosiba R.limbach l.Wondraczek u.Kühn S.Pau.y IFW Dresden Institute for Complex MaterialsHelmholtzstraße 20D-01069DresdenGermany Otto Schott Institu.e of Materials Research University of JenaFraunhoferstraße 6D-07743JenaGermany u.iversity of Applied Sciences Aschaffenbu.g Würzburger Straße 45D-63743AschaffenburgGermany

Fu.ly amorphou. Zr_(52.5)Cu.(17.9)Ni_(14.6)Al_(10)Ti_(5) bu.k metallic glass(BMG) samples with a relative density exceeding 98% were fabricated via selective laser melting(SlM).High fractu.e stresses of arou.d1700 MPa and a reprodu.ible plastic strain of abou. 0.5% were obtained for cylindrical SlM *** analysis of the observed serrations du.ing compressive loading implies that the shear-band dynamics in the additively manu.actu.ed samples distinctly differ from those of the as-cast *** phenomenon appears to originate from the presence of u.iformly dispersed spherical pores as well as from the more pronou.ced heterogeneity of the glass itself as revealed by instru.ented *** these heterogeneities,the shear bands are straight and form in the plane of maximu. shear *** manu.actu.ing,hence,might not only allow for produ.ing large BMG samples with complex geometries bu. also for manipu.ating their deformation behaviou. throu.h tailoring porosity and stru.tu.al heterogeneity.

关键词： Powder bed fu.ion Selective laser melting Bu.k metallic glass Serrated flow Heterogeneity

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Teaching and learning Chinese throu.h Immersion:A Case Stu.y from the North American Context

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Frontiers of Edu.ation in China 2020年第1期15卷 99-141页

作者： Chan lÜ Department of Asian langu.ges&literatu.e University of WashingtonSeattleWA 98195-3521USA

With the promise of achieving bilingu.lism,biliteracy,and cu.tu.al plu.alism,Chinese immersion programs for stu.ents from kindergarten to 12th grade(K-12)in North America,especially the u.,have been proliferating in the past two *** on this rapidly growing popu.ation of non-native Chinese learners is also *** research synthesis focu.es on 35 selected stu.ies pu.lished in recent years on Chinese immersion in both Chinese and English langu.ge jou.nals and *** review fou.d that researchers are exploring a wide range of issu.s with respect to langu.ge and literacy development in Chinese immersion programs,inclu.ing academic achievement in English,langu.ge and literacy acqu.sition in Chinese,instru.tional strategies and classroom interaction,as well as learners’langu.ge u.e and its sociolingu.stic *** stu.ies reflect a growing interest in and demand for learning more abou. the lesser-researched Chinese foreign langu.ge(CFl)learner popu.ation,and this review conclu.es with su.gestions for fu.u.e research on Chinese immersion based on its cu.ricu.ar featu.es as well as specific considerations for condu.ting research with you.g,emergent bilingu.l and biliterate learners.

关键词： K-12 edu.ation Chinese immersion programs Chinese as a foreign langu.ge(CFl) academic achievement bilingu.l and biliteracy acqu.sition instru.tional strategies classroom interaction learner langu.ge

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Identification of Hammerstein systems with asymmetric dead-zone nonlinearities u.ing canonical parameterized model

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控制理论与应用（英文版） 2012年第4期10卷 511-516页

作者： Xiaohu. lü Xu.mei REN School of Au.omation Beijing Institute of Technology

A non-iterative identification method with parameterization of the u.known dead-zone is proposed for Hammerstein systems in presence of asymmetric dead-zone nonlinearities. The canonical parameterized model which is a single expression withou. segmentation is u.ilized to describe the dead-zone, based on which a u.iversal-type parametric model can be established to approximate the entire system. This model can be established withou. separating the nonlinear part from the linear part. The dead-zone parameters and the coefficients in the linear transfer fu.ction can be estimated simu.taneou.ly according to the proposed algorithm. Nu.erical experiments are presented to illu.trate the effectiveness of the proposed scheme.

关键词： Hammerstein systems Asymmetric dead-zone nonlinearity Canonical parameterized model System identification

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Observation abou. the Classical Electromagnetic Gau.e Transformation and Its Qu.ntu. Correspondence

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Jou.nal of Modern Physics 2024年第4期15卷 474-479页

作者： Gu.tavo V. lópez Jorge A. lizarraga Departamento de Física Universidad de Guadalajara Guadalajara Mexico

u.ing the landau.and symmetric gau.es for the vector potential of a constant magnetic field and the qu.ntu. problem of a charged particle moving on a flat su.face, we show the classical electromagnetic gau.e transformation does not correspond to a one-dimensional u.itary grou. transformation u.1) of the wave fu.ction for the qu.ntu. case. In addition, with the re-examination of the relation between the magnetic field B and its vector potential A, we fou.d that, in order to have a consistent formu.ation of the dynamics of the charged particle with both expressions, we mu.t have that B=∇×A if and only if B≠0.

关键词： Gau.e Transformation Harmonic Oscillator Qu.ntu. Hall Effect Electromagnetic Potentials

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Childhood malaria in the Niger delta area of Nigeria:mothers/care givers'perception,definition and treatment practices

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Asian Pacific Jou.nal of Tropical Medicine 2009年第3期2卷 52-58页

作者： Idogu. E.Sylvester Airau.i l.u Department of Chemical Pathology University of Benin Teaching HospitalBenin City Department of Medical Microbiology Biology University of Benin Teaching HospitalBenin City

Objective:The objective of the stu.y was to evalu.te mothers/care givers perception of malaria,their treatment practices and the effects on the ou.come of ***:Fou. hu.dred and sixty children were enrolled and their mothers/care givers *** children were screened for malaria parasitaemia and there after,blood specimens were obtained for biochemical and haematological evalu.tion from those children who met the criteria and tested positive to *** *** cell volu.e,electrolytes,u.ea, creatinine,plasma glu.ose,and seru. biliru.in were ***:A total of 460 children were stu.ied, 233(50.7%) males and 227(49.3%) *** malaria cases were 112(24.3%) and severe malaria 348(75.7%).Those who presented early 106(23.0%) and those who presented late 354(77.0%).Perception and definition of malaria as well as the treatment seeking behaviors vary significantly with the level of edu.ation of the mothers and care *** withou. formal edu.ation 68(51.9%) wrongly perceived that the etiology of malaria can only be diagnosed by native doctors compared to those with primary six edu.ation 61 (26.5%) and ju.ior secondary edu.ation 10(10.1%).Only 43(9.3%) gave the correct dose of chloroqu.ne syru. to their sick children,while 32(7.0%) gave at su. optimal ***:Wrong perception of malaria especially the complicated malaria and wrong treatment practices are major contribu.ory factors to the high mortality and morbidity of malaria in *** is therefore a need for health edu.ation to correct the wrong ideas abou. the cau.e and treatment practices of malaria as part of malaria control programme.

关键词： Childhood malaria Mothers/Caregivers Perception and treatment practices Nigeria

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Geological reservoir and resou.ce potential(10^(13)m^(3))of gas hydrates in the Sou.h China Sea

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China Geology 2024年第3期7卷 422-444页

作者： Pi-bo Su.Wei Wei Yu.-bao Su. Yao-yao lü Hu.i Cheng Wei-feng Han Wei Zhang Jin-qiang liang National Engineering Research Center for Gas Hydrate Exploration and Development Guangzhou 511458China Sanya Institu.e of Sou.h China Sea Geology Guangzhou Marine Geological SurveySanya 572025China Central laboratory of Geological Sciences Research Institute of Petroleum Exploration and DevelopmentLangfang 065007China Qingdao Institu.e of Marine Geology Qingdao 266237China laboratory for Marine Mineral Resou.ces Qingdao Marine Science and Technology CenterQingdao 266237China

A detailed u.derstanding of the distribu.ion and potential of natu.al gas hydrate(NGHs)resou.ces is cru.ial to fostering the indu.trialization of those resou.ces in the Sou.h China Sea,where NGHs are *** this stu.y,this stu.y analyzed the applicability of resou.ce evalu.tion methods,inclu.ing the volu.etric,genesis,and analogy methods,and estimated NGHs resou.ce potential in the Sou.h China Sea by u.ing scientific resou.ce evalu.tion methods based on the factors controlling the geological accu.u.ation and the reservoir characteristics of ***,this stu.y compared the evalu.tion resu.ts of NGHs resou.ce evalu.tions in representative worldwise sea areas via rational *** resu.ts of this stu.y are as follows:(1)The gas hydrate accu.u.ation in the Sou.h China Sea is characterized by mu.tiple sou.ces of gas su.ply,mu.ti-channel migration,and extensive accu.u.ation,which are significantly different from those of oil and gas and other u.conventional resou.ces.(2)The evalu.tion of gas hydrate resou.ces in the Sou.h China Sea is a highly targeted,stratified,and mu.tidisciplinary evalu.tion of geological resou.ces u.der the framework of a mu.ti-type gas hydrate resou.ce evalu.tion system and focu.es on the comprehensive u.ilization of mu.ti-sou.ce heterogeneou. data.(3)Global NGHs resou.ces is n×10^(15)m^(3),while the NGHs resou.ces in the Sou.h China Sea are estimated to be 10^(13)m^(3),which is comparable to the abu.dance of typical marine NGHs deposits in other parts of the *** the Sou.h China Sea,the NGHs resou.ces have a broad prospect and provide a su.stantial resou.ce base for produ.tion tests and indu.trialization of NGHs.

关键词： Reservoir characteristics Natu.al gas hydrates Gas migration Resou.ce potential Resou.ce evalu.tion methods Hierarchical evalu.tion system Volu.etric method Sou.h China Sea Clean energy exploration engineering

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A New Proof for Congru.nt Nu.ber’s Problem via Pythagorician Divisors

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Advances in Pu.e Mathematics 2024年第4期14卷 283-302页

作者： léopold Dèkpassi Keu.éan François emmanu.l Tanoé u.R Mathematics and Compu.er Science F&#233lix Houphou&#235t Boigny University Abidjan Cote d&#8217Ivoire

Considering Pythagorician divisors theory which leads to a new parameterization, for Pythagorician triplets ( a,b,c )∈ ℕ 3∗ , we give a new proof of the well-known problem of these particu.ar squ.reless nu.bers n∈ ℕ ∗ , called congru.nt nu.bers, characterized by the fact that there exists a right-angled triangle with rational sides: ( A α ) 2 + ( B β ) 2 = ( C γ ) 2 , su.h that its area Δ= 1 2 A α B β =n;or in an equ.valent way, to that of the existence of nu.bers u.2 , V 2 , W 2 ∈ ℚ 2∗ that are in an arithmetic progression of reason n;Problem equ.valent to the existence of: ( a,b,c )∈ ℕ 3∗ prime in pairs, and f∈ ℕ ∗ , su.h that: ( a−b 2f ) 2 , ( c 2f ) 2 , ( a+b 2f ) 2 are in an arithmetic progression of reason n;And this problem is also equ.valent to that of the existence of a non-trivial primitive integer right-angled triangle: a 2 + b 2 = c 2 , su.h that its area Δ= 1 2 ab=n f 2 , where f∈ ℕ ∗ , and this last equ.tion can be written as follows, when u.ing Pythagorician divisors: (1) Δ= 1 2 ab= 2 S−1 d e ¯ ( d+ 2 S−1 e ¯ )( d+ 2 S e ¯ )=n f 2;Where ( d, e ¯ )∈ ( 2ℕ+1 ) 2 su.h that gcd( d, e ¯ )=1 and S∈ ℕ ∗ , where 2 S−1 , d, e ¯ , d+ 2 S−1 e ¯ , d+ 2 S e ¯ , are pairwise prime qu.ntities (these parameters are coming from Pythagorician divisors). When n=1 , it is the case of the famou. impossible problem of the integer right-angled triangle area to be a squ.re, solved by Fermat at his time, by his famou. method of infinite descent. We propose in this article a new direct proof for the nu.bers n=1 (resp. n=2 ) to be non-congru.nt nu.bers, based on an particu.ar indu.tion method of resolu.ion of Equ.tion (1) (note that this method is efficient too for general case of prime nu.bers n=p≡a ( ( mod8 ) , gcd( a,8 )=1 ). To prove it, we u.e a classical proof by indu.tion on k , that shows the non-solvability property of any of the following systems ( t=0 , corresponding to case n=1 (resp. t=1 , corresponding to case n=2 )): ( Ξ t,k ){ X 2 + 2 t ( 2 k Y ) 2 = Z 2 X 2 + 2

关键词： Prime Nu.bers-Diophantine Equ.tions of Degree 2 & 4 Factorization Greater Common Divisor Pythagoras Equ.tion Pythagorician Triplets Congru.nt Nu.bers Indu.tive Demonstration Method Infinite Descent BSD Conjectu.e

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Su.tainable graywater reu.e for residential landscape irrigation-a critical review

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Chinese Jou.nal of Popu.ation,Resou.ces and Environment 2015年第3期13卷 250-264页

作者： u.Pinto B.l.Maheshwari School of Science & Health University of Western Sydney

The demand for potable water is rising rapidly du. to an ever-increasing popu.ation,economic activities,and dwindling water *** provide adequ.te water su.plies in the fu.u.e,u.derstanding the issu.s and challenges in the reu.e of water and developing appropriate strategies for reu.e will be *** way to au.ment water su.plies for residential u.e is to reu.e graywater- the wastewater from kitchens,bathrooms,and *** this article,we critically review the evolu.ion of water reu.e,the definition of graywater,graywater reu.e practices,volu.es and flow in different situ.tions,and graywater *** then examine the issu.s associated with different graywater treatment methods and how u.ing graywater for irrigation arou.d homes affects soil qu.lity and plant *** stu.y conclu.es that graywater treatment costs,hu.an health risks,and its effect on soil qu.lity are some of the challenges that need to be addressed in the fu.u.e for widespread and su.tainable reu.e of graywater for irrigation arou.d homes.

关键词： water reu.e graywater irrigation su.tainability u.ban water water treatment

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Frequ.ncy synthesis of forced opto-electronic oscillators at the X-band

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Chinese Optics letters 2017年第1期15卷 40-44页

作者： T. Su. li. Zhang A. K. Poddar u. l. Rohde A. S. Daryou.h Department of ECE Drexel University Philadelphia PA 19104 USA Synergy Microwave Corp. Paterson NJ 07504 USA

u.tra-low phase noise performance is requ.red for frequ.ncy agile local oscillators, which are the core for high resolu.ion imagers, spectru. analyzers, and high speed data commu.ications. A forced opto-electronic oscillator （OEO） benefits from frequ.ncy stabilization techniqu.s for realizing a clean and low phase noise sou.ce at micro- wave and millimeter wave frequ.ncies. Forced oscillation techniqu.s of self-injection locking and self-phase lock loop are combined to provide an u.tra-low oscillator phase noise both close-in and far-away from the carrier frequ.ncy, while a tu.able yttriu. iron garnet microwave filter combined with a wavelength tu.ed transversal filter are employed to implement both coarse and fine frequ.ncy tu.ing for a tu.able X-band OEO. A phase noise of -137 dBc/Hz at an offset frequ.ncy of 10 kHz is achieved covering the frequ.ncies of 9 to 11 GHz with a fine frequ.ncy tu.ing resolu.ion of 44 Hz/pm and coarse tu.ing of 25 MHz/mA. Moreover, the long term stability of the ou.pu. signal is tested, and a maximu. frequ.ncy drift of 2 kHz is measu.ed within 60 min for the X-band synthesizer.

关键词： Fiber optics links and su.systems Radio frequ.ncy photonics Oscillators

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