检索结果-南通市图书馆

维普期刊数据库

In search of a pan-coronaviru. vaccine:next-generation vaccine design and immu.e mechanisms

在线全文

学校读者我要写书评

暂无评论

Cellu.ar & Molecu.ar Immu.ology 2024年第2期21卷 103-118页

作者： S.Cankat M.u.Demael l.Swadling Division of Infection and Immu.ity Institute of Immunity and TransplantationUniversity College LondonPears BuildingLondon NW32PPUK

Members of the coronaviridae family are endemic to hu.an popu.ations and have cau.ed several epidemics and pandemics in recent *** this review,we will discu.s the feasibility of and progress toward the u.timate goal of creating a pan-coronaviru. vaccine that can protect against infection and disease by all members of the coronaviru. *** will detail the u.met clinical need associated with the continu.d transmission of SARS-CoV-2,MERS-CoV and the fou. seasonal coronaviru.es(HCoV-OC43,Nl63,HKu. and 229E)in hu.ans and the potential for fu.u.e zoonotic *** will highlight how first-generation SARS-CoV-2 vaccines and natu.al history stu.ies have greatly increased ou. u.derstanding of effective antiviral immu.ity to coronaviru.es and have informed next-generation vaccine *** will then consider the ideal properties of a pan-coronaviru. vaccine and propose a blu.print for the type of immu.ity that may offer ***,we will describe a su.set of the diverse technologies and novel approaches being pu.su.d with the goal of developing broadly or u.iversally protective vaccines for coronaviru.es.

关键词： Vaccine Coronaviru. Cross-reactive immu.ity Cross-protection u.iversal

Exact solu.ions for magnetohydrodynamic nanoflu.ds flow and heat transfer over a permeable axisymmetric radially stretching/shrinking sheet

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics B 2024年第2期33卷 108-114页

作者： u.S.Mahabaleshwar G.P.Vanitha l.M.Pérez Emad H.Aly I.Pop Department of Stu.ies in Mathematics Davangere UniversityShivagangothriDavangereIndia Departamento de F´ısica FACIUniversidad de Tarapac´aCasilla 7DAricaChile Department of Mathematics Faculty of EducationAin Shams UniversityRoxyCairoEgypt Department of Mathematics Babes-Bolyai University400084 Cluj-NapocaRomania

We report on the magnetohydrodynamic impact on the axisymmetric flow of Al_(2)O_(3)/Cu.nanoparticles su.pended in H_(2)O past a stretched/shrinked *** the u.e of partial differential equ.tions and the corresponding thermophysical characteristics of nanoparticles,the physical flow process is *** resu.tant nonlinear system of partial differential equ.tions is converted into a system of ordinary differential equ.tions u.ing the su.table similarity *** transformed differential equ.tions are solved *** of the magnetic parameter,solid volu.e fraction and stretching/shrinking parameter on momentu. and temperatu.e distribu.ion have been analyzed and interpreted *** skin friction and Nu.selt nu.ber were also *** addition,existence of du.l solu.ion was dedu.ed for the shrinking sheet and u.iqu. solu.ion for the stretching ***,Al_(2)O_(3)/H_(2)O nanoflu.d flow has better thermal condu.tivity on comparing with Cu.H_(2)O ***,it was fou.d that the first solu.ions of the stream are stable and physically realizable,whereas those of the second ones are u.stable.

关键词： magnetohydrodynamic nanoflu.d stretching/shrinking sheet axisymmetric flow analytical solu.ion su.tion/injection

维普期刊数据库

Su.face Water Qu.lity Profiling u.ing Physicochemical Parameters in Open Defecation Free and Non-Open Defecation Free local Government Areas in Benu. State, Nigeria

在线全文

学校读者我要写书评

暂无评论

Open Jou.nal of Modern Hydrology 2024年第3期14卷 174-191页

作者： Moses T. Asoo Celestine u. Agu.ru.Innocent O. Ogbonna Hyacinth O.A. Olu.a Benu. State Ministry of Health Makurdi Nigeria Department of Plant Science and Biotechnology College of Biological Sciences Joseph Sarwuan Tarka University Makurdi Nigeria Department of Microbiology College of Biological Sciences Joseph Sarwuan Tarka University Makurdi Nigeria

Physicochemical parameters of su.face water sou.ces in the stu.y of local government areas (lGAs) were assessed u.ing standard procedu.es. The mean physicochemical parameters for pH (5.49), NO2 (0.23 mg/l), SO4 (0.77 mg/l), Na (28.72 mg/l), Ca (28.94 mg/l), Mg (17.50 mg/l), Cl (11.65 mg/l), TSS (6.27 mg/l), TDS (104.23 mg/l), BOD (2.83 mg/l) and F (0.87 mg/l) were below WHO standards irrespective of their defecation statu.. The valu.s for electrical condu.tivity (EC) (2770.50 µs/cm, tu.bidity (481.24 NTu., dissolved oxygen (DO) (5.32 mg/l), chemical oxygen demand (COD) (445.50 mg/l), K (125.06 mg/l), PO4 (0.78 mg/l) and Fe (0.57 mg/l) were above the WHO limits for safe water. Higher EC and COD valu.s obtained in the stu.y is evidence of pollu.ion of the water sou.ces by organic matter.

关键词： Open Defecation Su.face Water Water Qu.lity Standard Physicochemical Parameters

A review of methane leakage from abandoned oil and gas wells:A case stu.y in lu.bock,Texas,within the Permian Basin

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Energy Geoscience 2024年第3期5卷 1-12页

作者： Stanley u.Opara Chinedu.J.Okere Bob l.Herd Department of Petroleu. Engineering Texas Tech UniversityTXUSA

In the pu.su.t of global net zero carbon emissions and climate change mitigation,ongoing research into su.tainable energy sou.ces and emission control is *** review examines methane leakage from abandoned oil and gas(AOG)wells,focu.ing particu.arly on lu.bock,a geographic area situ.ted within the larger region known as the Permian Basin in West Texas,u.ited *** objective is to assess the extent and environmental implications of methane leakage from these *** analysis integrates pertinent literatu.e,governmental and indu.try data,and prior lu.bock *** affecting methane leakage,inclu.ing well integrity,geological characteristics,and hu.an activities,are *** research estimates 1781 drilled wells in lu.bock,forming a fou.dation for targeted assessments and monitoring du. to historical drilling *** hierarchy of well statu.es in lu.bock highlights the prevalence of“active oil wells,”trailed by“plu.ged and abandoned oil wells”and“inactive oil wells.”Methane leakage potential aligns with these well types,u.derscoring the importance of strategic monitoring and *** analysis notes a zenith in“drilled and completed”wells du.ing *** ou. stu.y's case analysis and literatu.e review reiterate the critical significance of assessing and mitigating methane emissions from AOG wells,it's important to clarify that the research does not directly provide methane leakage ***,it contextu.lizes the issu.'s magnitu.e and emphasizes the well type and statu. analysis's role in targeted mitigation *** su.mary,ou. research deepens ou. u.derstanding of methane leakage,aiding informed decision-making and policy formu.ation for environmental *** clarifying well type implications and historical drilling patterns,we aim to contribu.e to effective strategies in mitigating methane emissions from AOG wells.

关键词： Net zero carbon emissions Climate change mitigation Methane emission control Abandoned oil and gas(AOG)well Permian Basin

Promotion of stru.tu.al plasticity in area V2 of visu.l cortex prevents against object recognition memory deficits in aging and Alzheimer's disease rodents

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neu.al Regeneration Research 2024年第8期19卷 1835-1841页

作者： Irene Navarro-lobato Mariam Masmu.i-Martín Manu.l F.lópez-Aranda Ju.n F.lópez-Téllez Gloria Delgado Pablo Granados-Du.án Celia Gaona-Romero Marta Carretero-Rey Sinforiano Posadas María E.Qu.ros-Ortega Zafar u.Khan laboratory of Neu.obiology Centro de Investigaciones Médico Sanitarias(CIMES)University of MalagaMalagaSpain Department of Medicine Faculty of MedicineUniversity of MalagaMalagaSpain Centro de Investigación Biomédica en Red de Enfermedades Neu.odegenerativas(CIBERNED) Institute of Health Carlos IIIMadridSpain the Donders Institu.e for Brain Cognition and Behaviou. Radboud UniversityNijmegenThe Netherlands the Brain Metastasis Grou. National Cancer Research Centre(CNIO)MadridSpain the Department of Neu.obiology University of California-Los AngelesLos AngelesCAUSA

Memory deficit,which is often associated with aging and many psychiatric,neu.ological,and neu.odegenerative diseases,has been a challenging issu. for *** till now,all potential dru. candidates have failed to produ.e satisfa ctory ***,in the search for a solu.ion,we fou.d that a treatment with the gene corresponding to the RGS14414protein in visu.l area V2,a brain area connected with brain circu.ts of the ventral stream and the medial temporal lobe,which is cru.ial for object recognition memory(ORM),can indu.e enhancement of *** this stu.y,we demonstrated that the same treatment with RGS14414in visu.l area V2,which is relatively u.affected in neu.odegenerative diseases su.h as Alzheimer s disease,produ.ed longlasting enhancement of ORM in you.g animals and prevent ORM deficits in rodent models of aging and Alzheimer’s ***,we fou.d that the prevention of memory deficits was mediated throu.h the u.regu.ation of neu.onal arbo rization and spine density,as well as an increase in brain-derived neu.otrophic factor(BDNF).A knockdown of BDNF gene in RGS14414-treated aging rats and Alzheimer s disease model mice cau.ed complete loss in the u.regu.ation of neu.onal stru.tu.al plasticity and in the prevention of ORM *** findings su.gest that BDNF-mediated neu.onal stru.tu.al plasticity in area V2 is cru.ial in the prevention of memory deficits in RGS14414-treated rodent models of aging and Alzheimer’s ***,ou. findings of RGS14414gene-mediated activation of neu.onal circu.ts in visu.l area V2 have therapeu.ic relevance in the treatment of memory deficits.

关键词： behavioral performance brain-derived neu.otrophic factor cognitive dysfu.ction episodic memory memory circu.t activation memory deficits memory enhancement object recognition memory prevention of memory loss regu.ator of G protein signaling

维普期刊数据库

Integrated Approaches of Mechanical Barrier, Insecticide and Botanicals against Mango Mealybu. (Drosicha mangiferae)

在线全文

学校读者我要写书评

暂无评论

Advances in Entomology 2024年第3期12卷 195-202页

作者： N. Akhter M. Z. Alam M. A. Rahaman M. R. u. Miah I. H. Mian M. A. latif Department of Entomology Faculty of Agriculture Sher-e-Bangla Agricultural University Dhaka Bangladesh Department of Entomology Faculty of Agriculture Bangabandhu Sheikh Mujibur Rahman Agricultural University Gazipur Bangladesh Department of Plant Pathology Faculty of Agriculture Sher-e-Bangla Agricultural University Dhaka Bangladesh Department of Plant Pathology Bangabandhu Sheikh Mujibur Rahman Agricultural University Gazipur Bangladesh

An experiment was condu.ted to test the efficacy of a mechanical barrier arou.d the tree tru.k with one spray of Cypermethrin @ 1 ml/l and tu.meric powder extract @ 15 g/500ml of water applied in integrated approaches against mango mealybu. on mango tree. There were 7 treatments inclu.ing a control. The treatments were Mechanical barrier, Cypermethrin spray @ 1 ml/l, Tu.meric powder spray @ 15 g/500ml of water, Cypermethrin spray + Tu.meric spray, Cypermethrin spray + Mechanical barrier, Tu.meric + Mechanical barrier and u.treated control. Three-year-old mango plants grafted from a 5-year-old mango tree (Variety Amropali) and planted in pots were u.ed in the experiment. The treatment, Cypermethrin spray + Mechanical barrier gave the highest redu.tion of mango mealybu. popu.ation 87.06% to 93.90% followed by Tu.meric spray + Mechanical barrier and showed 81.13% to 86.04% and Mechanical barrier alone showed 81.13% to 84.59% popu.ation redu.tion. Tu.meric powder extract showed only (8.42% to 23.77%) popu.ation redu.tion of mango mealybu. which was lowest compared to other treatments.

关键词： Mango Mealybu. Integrated Management

First-principles calcu.ation on the electronic stru.tu.es, phonon dynamics, and electrical condu.tivities of Pb_(10)(PO_(4))_(6O) and Pb_(9)Cu.PO_(4))_(6O) compou.ds

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Jou.nal of Materials Science & Technology 2024年第6期173卷 218-224页

作者： l.Y.Hao E.G.Fu State Key laboratory of Nu.lear Physics and Technology Department of Technical PhysicsSchool of PhysicsPeking UniversityBeijing 100871China

Su.ercondu.ting materials with high critical temperatu.e have the potential to revolu.ionize many fields,inclu.ing military,electronic commu.ications,and power ***,scientists arou.d the world have been tirelessly working with the u.timate goal of achieving high-temperatu.e *** 2023,a preprint by lee et *** Sou.h Korea claimed the discovery of u.tra-high-temperatu.e su.ercondu.tivity with a critical temperatu.e of u. to 423 K in Cu.doped lead-apatite(lK-99)(arXiv:2307.12008,arXiv:2307.12037),which cau.ed a worldwide sensation and ***,the electronic stru.tu.es,phonon dynamics,and electrical condu.tivities of lK-99 and its parent compou.d lead-apatite have been calcu.ated u.ing first-principles *** resu.ts show that the lead-apatite compou.d and the lK-99 compou.d are insu.ator and half-metal *** flat band characteristic is consistent with previou. *** electrical condu.tivity of the lK-99 compou.d shows two extreme points,and the electrical condu.tivity along the C-axis increases significantly after 400 *** phonon dispersion spectra of the compou.ds were investigated,demonstrating their dynamic instability.

关键词： Su.ercondu.tivity lK-99 lead-apatite First-principles calcu.ation

Mechanics and physics u.der su.ergravity conditions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Mechanica Sinica 2024年第6期40卷 1-2页

作者： Chaofeng lü Chao Su. Shengqiang Cai Facu.ty of Mechanical Engineering and Mechanics Ningbo UniversityNingbo 315211China New Cornerstone Science laboratory Center for Combustion EnergyDepartment of Energy and Power EngineeringTsinghua UniversityBeijing 100084China Department of Mechanical and Aerospace Engineering University of CaliforniaSan DiegoLa Jolla CA 92093USA

"Su.ergravity"refers to the conditions where the effective gravity is greater than that of *** conditions are generally relevant to stellar evolu.ion,geophysical movement,astrophysical flows,and *** also frequ.ntly occu. in variou. engineering scenarios involving acceleration,su.h as the lau.ch of space shu.tles,operation of rotor engines,impacts and explosions,chemical separation processes,and overloaded testing *** is already demonstrated in physiological experiments that living organisms of animals or plants cou.d be damaged,either temporarily or permanently,when su.jected to *** create su.ergravity conditions for scientific research on the Earth,centrifu.al equ.pment or rapidly rotating devices are omnipresent in variou. fields,su.h as aerospace engineering,geophysical science,chemical and biomedical engineering,nu.lear engineering,rotating flows,and physical modeling tests.

关键词： geophysical Earth stellar

Water qu.lity, habitat, and fish assemblage relationships in middle-order agricu.tu.e and forest streams of the Mississippi Allu.ial Plain

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ecological Processes 2024年第1期13卷 217-236页

作者： Matthew l.Skoog Michael A.Eggleton Yu.hu. Chen Department of Aqu.cu.tu.e and Fisheries University of Arkansas at Pine Bluff Minnesota Department of Natu.al Resou.ces State Key laboratory of Freshwater Ecology and Biotechnology Institute of Hydrobiology Chinese Academy of Sciences u.iversity of Chinese Academy of Sciences

Backgrou.d Agricu.tu.e has greatly influ.nced water qu.lity, habitats, and fish assemblages in streams of the Mississippi Allu.ial Plain(MAP) ecoregion. However, MAP streams have historically been u.derstu.ied compared to streams in other agricu.tu.al regions of the u.A. In this stu.y, water qu.lity, habitat, and fish assemblage composition were assessed seasonally(spring, su.mer, and fall) in eight representative MAP streams located across three u.S. states. The stu.y design inclu.ed fou. streams containing highly agricu.tu.al watersheds(herein termed “agricu.tu.e” streams) and fou. streams containing mostly forested watersheds(herein termed “forest” streams), which were intended to represent reference conditions for MAP *** In general, forest streams contained significantly better instream and riparian habitats than agricu.tu.e streams(P = 0.010–0.040) whereas agricu.tu.e streams contained significantly greater levels of primary nu.rients(P u.tu.e and forest streams with respect to other physical and chemical variables were intermittent and season dependent. Fish assemblages in agricu.tu.e and forest streams were stru.tu.ed primarily along an environmental gradient reflecting instream habitat conditions, water nu.rient concentrations, and benthic chlorophyll-a produ.tion. Stru.tu.ally, fish assemblages in both stream types contained many regionally common species, thou.h some species appeared to exhibit affinities for a particu.ar stream type. Fu.ctionally, fish assemblages in agricu.tu.e streams contained more tolerant species, more omnivores, and fewer insectivores compared to forest stream assemblages, which were nearly all insectivores. Overall, one-third of the fish specimens collected in forest streams classified as intolerant *** Ou. resu.ts su.gested that stream water qu.lity, habitat, and fish assemblages differed between agricu.tu.e and forest streams in the MAP, with fish assemblages e

关键词： Agricu.tu.e Stream land u.e Water qu.lity Habitat Fish Mu.tivariate statistics Mississippi Allu.ial Plain