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ELEMENTAL IQUIQUE经济适用房扩展

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城市环境设计 2010年第Z2期 268-271页

作者： Alejandro Aravena Alfonso Montero Tonnas Cortese emilio de la cerrda Andres lacobelli

智利政府要求我们解决位于智利沙漠中的Iquique城Quinta Monroy区5000m2的地段100户家庭的住房问题,他们在过去的30年中非法占有市中心。我们需要在现行房屋政策的框架范围内,使用7500美元的补贴金购置土地,建设各种基础设施和建筑。Ele... 详细信息

智利政府要求我们解决位于智利沙漠中的Iquique城Quinta Monroy区5000m2的地段100户家庭的住房问题,他们在过去的30年中非法占有市中心。我们需要在现行房屋政策的框架范围内,使用7500美元的补贴金购置土地,建设各种基础设施和建筑。Elemental的首要任务就是找到看待这个问题的新方式,将7500美元的价值翻100倍,

关键词：美元本位币 ELEMENTAL IQUIQUE 智利

IBD5 polymorphisms in inflammatory bowel disease: Association with response to infliximab

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World Journal of Gastroenterology 2005年第8期11卷 1187-1192页

作者： Elena Urcelay Juan Luis Mendoza Alfonso Martínez laura Fernández Carlos Taxonera Manuel Díaz-Rubio emilio G.de la Concha Immunology department Gastroenterology department

AIM: Inflammatory bowel diseases (IBD) are multifactorial pathologies of unknown etiology. One susceptibility locus, IBD5, has been mapped to chromosome 5q31. We analyzed our Spanish cohorts of Crohn's disease (CD) and ulcerative colitis (DC) patients to determine whether this locus is associated with IBD, and to ascertain the main clinical phenotype influenced by this risk factor. The kind of interaction, either genetic heterogeneity or epistasis, between this IBD5 susceptibility region and the NOD2/CARD15 gene mutations was studied as well. Finally, we assessed whether this locus can predict response to infliximab therapy. METHODS: A case control study was performed with 274 CD and 211 UC patients recruited from a single center and 511 healthy ethnically matched controls. Two polymorphisms were genotyped in the IBD5 locus and three in the CARD15/NOD2 gene. RESULTS: Our results evidence association only with CD especially with the fistulizing phenotype and in the absence of NOD2/CARD15 variants (mutant allele frequency in patients vs controls: OR = 2.03, 95% CI = 1.35-3.06, Placking response to infliximab (RR = 3.88, 95% CI = 1.18-12.0, Plar trend to the one observed in CD is found within the worse prognosis group. CONCLUSION: The IBD5 variants may enhance an individual carrier's risk for CD, mainly in the absence of the NOD2/CARD15 mutations and in fistulizing patients. The data presented suggest the potential role of the 5q31 polymorphisms as markers of response to infliximab.

关键词： Crohn's disease Ulcerative colitis 5q31 polymorphisms Infliximab

Federated Network Intelligence Orchestration for Scalable and Automated FL-Based Anomaly detection in B5G Networks

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Computers, Materials & Continua 2024年第7期80卷 163-193页

作者： Pablo Fernández Saura José M.Bernabé Murcia emilio García de la Calera Molina Alejandro Molina Zarca Jorge Bernal Bernabé Antonio F.Skarmeta Gómez department of Information and Communications Engineering University of MurciaMurcia30100Spain University Center of defense Spanish Air Force AcademySan Javier30720Spain

The management of network intelligence in Beyond 5G(B5G)networks encompasses the complex challenges of scalability,dynamicity,interoperability,privacy,and *** are essential steps towards achieving the realization of truly ubiquitous Artificial Intelligence(AI)-based analytics,empowering seamless integration across the entire Continuum(Edge,Fog,Core,Cloud).This paper introduces a Federated Network Intelligence Orchestration approach aimed at scalable and automated Federated Learning(FL)-based anomaly detection in *** leveraging a horizontal Federated learning approach based on the FedAvg aggregation algorithm,which employs a deep autoencoder model trained on non-anomalous traffic samples to recognize normal behavior,the systemorchestrates network intelligence to detect and prevent *** into a B5G Zero-touch Service Management(ZSM)aligned Security Framework,the proposal utilizes multi-domain and multi-tenant orchestration to automate and scale the deployment of FL-agents and AI-based anomaly detectors,enhancing reaction capabilities against *** proposed FL architecture can be dynamically deployed across the B5G Continuum,utilizing a hierarchy of Network Intelligence orchestrators for real-time anomaly and security threat *** includes FL enforcement operations for interoperability and extensibility,enabling dynamic deployment,configuration,and reconfiguration on *** validation of the proposed solution was conducted through dynamic orchestration,FL,and real-time anomaly detection processes using a practical test *** of key performance metrics,leveraging the 5G-NIDD dataset,demonstrates the system’s capability for automatic and near real-time handling of anomalies and attacks,including real-time network monitoring and countermeasure implementation for mitigation.

关键词： Federated learning 6G orchestration anomaly detection security policy

Efficiency in hydrocarbon degradation and biosurfactant production by Joostella sp.A8 when grown in pure culture and consortia

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Journal of Environmental Sciences 2018年第5期30卷 115-126页

作者： Carmen Rizzo Alessandro Ciro Rappazzo Luigi Michaud emilio de Domenico Carlos Rochera Antonio Camacho Angelina Lo Giudice department of Chemical BiologicalPharmaceutical and Environmental Sciences(ChiBioFarAm)University of MessinaViale Ferdinando Stagno d'Alcontres 3198166 MessinaItaly Institute for the Coastal Marine Environment National Research Council(IAMC-CNR)Spianata San Raineri 8698122 MessinaItaly Cavanilles Institute for Biodiversity and Evolutionary Biology University of ValenciaCarrer del Catedratic Jose Beltran Martinez 246980 PaternaValenciaSpain Regional Centre for Water Studies(CREA) University of Castilla-La ManchaC/Altagracia 5013071 Ciudad RealSpain

Joostella strains are emerging candidates for biosurfactant production. Here such ability was analyzed for Joostella strain A8 in comparison with Alcanivorax strain A53 and Pseudomonas strain A6, all previously isolated from hydrocarbon enrichment cultures made of polychaete homogenates. In pure cultures Joostella sp. A8 showed the highest stable emulsion percentage（78.33%）, hydrophobicity rate（62.67%）, and an optimal surface tension reduction during growth in mineral medium supplemented with diesel oil（reduction of about 12 mN/m）, thus proving to be highly competitive with Alcanivorax and Pseudomonas strains. During growth in pure culture different level of biodegradation were detected for Alcanivorax strain A53（52.7%）,Pseudomonas strain A6（38.2%） and Joostella strain A8（26.8%）. When growing in consortia,isolates achieved similar abundance values, with the best efficiency that was observed for the Joostella-Pseudomonas co-culture. Gas-chromatographic analysis revealed an increase in the biodegradation efficiency in co-cultures（about 90%）, suggesting that the contemporary action of different bacterial species could improve the process. Results were useful to compare the efficiencies of well-known biosurfactant producers（i.e. Pseudomonas and Alcanivorax representatives） with a still unknown biosurfactant producer, i.e. Joostella, and to confirm them as optimal biosurfactant-producing candidates.

关键词： Joostella Biosurfactants Co-cultures Hydrocarbon degradation Biodegradation efficiency

Sharp Bounds for Fractional One-sided Operators

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Acta Mathematica Sinica,English Series 2016年第11期32卷 1255-1278页

作者： Maria Silvina RIVEROS Raul emilio VIDAL FaMAF-CIEM UNC-CONICET Ciudad Universitaria 5000 Cdrdoba Argentina

In this paper, we characterize the sharp boundedness of the one-sided fractional maximal function for one-weight and two-weight inequalities. Also a new two-weight testing condition for the one-sided fractional maximal function is introduced extending the work of Martin-Reyes and de la Torre. Improving some extrapolation result for the one-sided case, we get weak sharp bounded estimates for one-sided fractional maximal function and weak and strong sharp bounded estimates for one-sided fractional integral.

关键词： One-sided fractional integrals one-sided maximal fractional function extrapolation Saw-yer weights

Analyzing the genomic and transcriptomic architecture of milk traits in Murciano-Granadina goats

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Journal of Animal Science and Biotechnology 2020年第3期11卷 649-666页

作者： Dailu Guan Vincenzo landi María Gracia Luigi-Sierra Juan Vicente delgado Xavier Such Anna Castelló Betlem Cabrera emilio Mármol-Sánchez Javier Fernández-Alvarez JoséLuis Ruiz de la Torre Casañas Amparo Martínez Jordi Jordana Marcel Amills Centre for Research in Agricultural Genomics(CRAG) CSIC-IRTA-UAB-UBUniversitat Autònoma de Barcelona08193 BellaterraSpain departamento de Genética Universidad de Córdoba14071 CórdobaSpain departament de Ciència Animal i dels Aliments Facultat de VeterinàriaUniversitat Autònoma de Barcelona08193 BellaterraSpain Asociación Nacional de Criadores de Caprino de Raza Murciano-Granadina(CAPRIGRAN) 18340 GranadaSpain Servei de Granges i Camps Experimentals Universitat Autònoma de Barcelona08193 BellaterraSpain

Background:In this study,we aimed to investigate the molecular basis of lactation as well as to identify the genetic factors that influence milk yield and composition in *** achieve these two goals,we have analyzed how the mRNA profile of the mammary gland changes in seven Murciano-Granadina goats at each of three different time points,i.e.78 d(T1,early lactation),216 d(T2,late lactation)and 285 d(T3,dry period)after ***,we have performed a genome-wide association study(GWAS)for seven dairy traits recorded in the 1st lactation of 822 Murciano-Granadina ***:The expression profiles of the mammary gland in the early(T1)and late(T2)lactation were quite similar(42 differentially expressed genes),while strong transcriptomic differences(more than one thousand differentially expressed genes)were observed between the lactating(T1/T2)and non-lactating(T3)mammary glands.A large number of differentially expressed genes were involved in pathways related with the biosynthesis of amino acids,cholesterol,triglycerides and steroids as well as with glycerophospholipid metabolism,adipocytokine signaling,lipid binding,regulation of ion transmembrane transport,calcium ion binding,metalloendopeptidase activity and complement and coagulation *** regard to the second goal of the study,the performance of the GWAS allowed us to detect 24 quantitative trait loci(QTLs),including three genome-wide significant associations:QTL1(chromosome 2,130.72-131.01 Mb)for lactose percentage,QTL6(chromosome 6,78.90-93.48 Mb)for protein percentage and QTL17(chromosome 17,11.20 Mb)for both protein and dry matter ***,QTL6 shows positional coincidence with the casein genes,which encode 80%of milk ***:The abrogation of lactation involves dramatic changes in the expression of genes participating in a broad array of physiological processes such as protein,lipid and carbohydrate metabolism,calcium homeostasis,cell death and tissue remo

关键词： Casein genes Dairy traits GWAS lactation QTLs RNA-Seq

Climate change for coastal areas:Risks,adaptation and acceptability

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Advances in Climate Change Research 2020年第4期11卷 295-296页

作者： emilio BASTIDAS-ARTEAGA Axel CREACH laboratoire des Sciences de l'Ingenieur pour l'Environnement LaSIE UMR CNRS 7356La Rochelle UniversiteLa Rochelle17042France laboratoire de Geographie Physique UMR CNRS 8591 Sorbonne UniversiteParis75005France

Coastal areas are attractive for people and activities worldwide,because of globalization(90% of global trade is seaborn trade),leisure and weather *** example,23% of the worldwide population is living at less than 100 km of seashore and under 100 m high above sea level(Small and Nicholls,2003).In consequence,its population density rate is 112 km^(-2) compared to a worldwide density rate of 44 km^(-2).

关键词： conditions. coastal attractive

TIME PERIODIC SOLUTIONS TO THE EVOLUTIONARY OSEEN MOdeL FOR A GENERALIZED NEWTONIAN INCOMPRESSIBLE FLUID

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Acta Mathematica Scientia 2023年第4期43卷 1645-1667页

作者：岑金夏 Stanislaw MIGóRSKI emilio VILCHES 曾生达 School of Mathematical Sciences Zhejiang Normal UniversityJinhua 321004China Jagiellonian University in Krakow Chair of Optimization and Controlul.Lojasiewicza 630348 KrakowPoland Instituto de Ciencias de la Ingenier´ıa Universidad de O’HigginsAv.Libertador Bernardo OHiggins 6112841959 RancaguaChile Guangxi Colleges and Universities Key laboratory of Complex System Optimization and Big Data Processing Yulin Normal UniversityYulin 537000China department of Mathematics Nanjing University Nanjing 210093China Jagiellonian University in Krakow Faculty of Mathematics and Computer Scienceul.Lojasiewicza 630348 KrakowPoland

In this paper we study a nonstationary Oseen model for a generalized Newtonian incompressible fluid with a time periodic condition and a multivalued,nonmonotone friction ***,a variational formulation of the model is obtained;that is a nonlinear boundary hemivariational inequality of parabolic type for the velocity ***,an abstract first-order evolutionary hemivariational inequality in the framework of an evolution triple of spaces is *** mild assumptions,the nonemptiness and weak compactness of the set of periodic solutions to the abstract inequality are ***,a uniqueness theorem for the abstract inequality is established by using a monotonicity ***,we employ the theoretical results to examine the nonstationary Oseen model.

关键词： nonstationary Oseen model Newtonian incompressible fluid hemivariational inequality periodic solution generalized subgradient

Prevention of de novo HBV infection by the presence of anti-HBs in transplanted patients receiving core antibody-positive livers

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World Journal of Gastroenterology 2006年第13期12卷 2070-2074页

作者： Rafael Barcena Gloria Moraleda Javier Moreno M Dolores Martín emilio de Vicente Jesús Nuo M Luisa Mateos Santos del Campo department of Gastroenterology Hospital Ramón y Cajal Facultad de MedicinaUniversidad de AlcaláCtra. Colmenar Km 9.128034 MadridSpain Digestive Diseases Hospital Universitario la Paz 28034 MadridSpain department of Surgery Hospital Ramón y Cajal Facultad de MedicinaUniversidad de Alcalá28034 MadridSpain department of Microbiology Hospital Ramón y Cajal Facultad de MedicinaUniversidad de Alcalá28034 MadridSpain

AIM： To analyze whether the presence of anti-HBs in liver transplant recipients is effective in preventing HBV infection. METHODS： Twenty-three patients receiving anti-HBc positive liver were studied. Nine recipients were anti-HBc positive as a result of previous HBV infection. Of them, one also received HBV vaccine during the pre-liver transplantation period. Fourteen recipients were anti-HBs positive due to HBV vaccine administered during the pretransplant period. Liver biopsy was obtained in 10/14 anti-HBc negative/anti-HBs positive recipients and in 4/9 anti-HBc positive recipients. RESULTS： After a mean foUow-up period of 46 months, 1 recipient with protective serum anti-HBs levels developed de novo HBV infection as a consequence of immune escape HBV mutants. Among the 14 vaccinated anti-HBc negative/anti-HBs positive recipients, 1/10 patients with available liver biopsy （10%） had liver HBV-DNA at 13 mo post-liver transplantation without serum viral markers and did not develop de novo HBV *** vaccinated anti-HBc positive recipient without HBV vaccine response was HBV-DNA positive in serum and liver, viral DNA was continuously negative in the following tests, so a spontaneous seroconversion was diagnosed. CONCLUSION： The presence of anti-HBs as a result of HBV vaccine or past HBV infection seems to be effective at protecting patients receiving livers from anti-HBc positive donors. However, the emergence of immune escape HBV mutants, which can evade the anti-HBs protection, should be considered as a risk of HBV infection.

关键词： HBV vaccine Liver transplantation de novo HBV infection Hepatitis B core antibody