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New Approach in Processing of the Infrared Image Sequence for Moving Dim Point Targets Detection

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Journal of Signal and Information Processing 2013年第3期4卷 144-149页

作者： mohamed abdo M. Hongzuo Li School of Electronics and Information Engineering Changchun University of Science and Technology Changchun city China.

The development of an efficient moving target detection algorithm in IR-image sequence is considered one of the most critical research fields in modern IRST (Infrared Search and Track) systems, especially when dealing with moving dim point targets. In this paper we propose a new approach in processing of the Infrared image sequence for moving dim point targets detection built on the transformation of the IR-image sequence into 4-vectors for each frame in the sequence. The results of testing the proposed approach on a set of frames having a simple single pixel target performing a different motion patterns show the validity of the approach for detecting the motion, with simplicity in calculation and low time consumption.

关键词： IR Image Sequence Processing Statistical Processing Dim Point Target Detection

Pancreatic injury in patients with septic shock: A literature review

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World Journal of Gastrointestinal Oncology 2016年第7期8卷 526-531页

作者： Anis Chaari Karim Abdel Hakim Kamel Bousselmi Mahmoud Etman mohamed El Bahr Ahmed El Saka eman Hamza mohamed Ismail Elsayed Mahmoud Khalil Vipin Kauts William Francis Casey Department of Intensive Care King Hamed University Hospital

Sepsis and septic shock are life threatening condition associated with high mortality rate in critically-ill patients. This high mortality is mainly related to the inadequacy between oxygen delivery and cellular demand leading to the onset of multiorgan dysfunction. Whether this multiorgan failure affect the pancreas is not fully investigated. In fact, pancreatic injury may occur because of ischemia, overwhelming inflammatory response, oxidative stress, cellular apoptosis and/or metabolic derangement. Increased serum amylase and/or lipase levels are common in patients with septic shock. However, imaging test rarely reveal significant pancreatic damage. Whether pancreatic dysfunction does affect the prognosis of patients with septic shock or not is still a matter of debate. In fact, only few studies with limited sample size assessed the clinical relevance of the pancreatic injury in this group of patients. In this review, we aimed to describe the epidemiology and the physiopathology of pancreatic injury in septic shock patients, to clarify whether it requires specific management and to assess its prognostic value. Our main finding is that pancreatic injury does not significantly affect the outcome in septic shock patients. Hence, increased serum pancreatic enzymes without clinical features of acute pancreatitis do not require further imaging investigations and specific therapeutic intervention.

关键词： Septic shock Pancreas Lipase Amylase Prognosis

Characterisation of Class 1 Integron among <i>Escherichia coli</i>Isolated from Mansoura University Hospitals in Egypt

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Advances in Microbiology 2015年第4期5卷 269-277页

作者： mohamed mohamed Adel El-Sokkary eman Salama Abdelmegeed Microbiology Department Faculty of Pharmacy Mansoura University Mansoura Egypt

Extensive use of antibacterials in clinical practice has been associated with increasing frequency of multi-resistant E. coli strains. Genetic elements such as Class 1 integrons have an important role in resistance development. In the current study, a total of 84 E. coli clinical isolates from Mansoura hospitals patients in Egypt were screened for antibacterial susceptibility against 12 different antibacterials. High resistance rates were identified for Ampicillin (92.9%) and sulfamethoxazole/ trimethoprim (84.5%). Class 1 integron was investigated in E. coli isolates by PCR. As a result, Class 1 integron was identified in 51.2% of these isolates. The contents of amplified integron varriable regions, were digested by Alu I restriction endonuclease. Cluster analysis of Class 1 integron digested varriable regions revealed that RFLP digested fragments generated could be classified into 9 different patterns, namely A, B, C, D, E, F, G, H and I. The most prevalent genotype was identifed in Group D. PCR and sequencing were used for detection of antimicrobial resistance genes harbored in integrons of Group D. As a result, main phylogenetic group identified harbored integron cassette carrying resistance gene for two antimicrobial groups namely aminoglycoside and trimethoprim. Multiresistance profiles in Group D exhibited association between antimicrobial resistance and integron presence. These findings suggest that the strategy for treatment of patients with E. coli infections needs to be revised. Furthermore, the high prevalence of Class 1 integron carrying gene confirms the importance of integron-mediated antimicrobial gene cassettes.

关键词： Integron Antimicrobial Resistance E. coli RFLP

Predictors of anti-SARS-CoV-2 seropositivity:An Egyptian population-based study

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Infectious Medicine 2022年第2期1卷 113-123页

作者： Engy mohamed El-Ghitany Ayat Ashour Azza Galal Farghaly Mona H.Hashish eman A.Omran Department of Tropical Health High Institute of Public HealthAlexandria UniversityAlexandriaEgypt Department of Family Health High Institute of Public HealthAlexandria UniversityAlexandriaEgypt Department of Microbiology High Institute of Public HealthAlexandria UniversityAlexandriaEgypt

Background:Population-based studies on the determinants of COVID-19 seroprevalence constitute a cornerstone in guiding appropriate preventive *** studies are scarce in Egypt,thus we conducted this study to explore risk factors for SARS-CoV-2 ***:This survey included 2919 participants from 10 Egyptian *** were tested for SARS-CoV-2 spike(S)and nucleocapsid(N)*** and multivariate analyses were performed to identify associated factors and predictors of seropositivity regarding sociodemographic factors,clinical data,and personal practices of participants.A subgroup analysis was performed to investigate the occupational risks of ***:Seropositivity was recorded in 1564 participants(53.6%).Independent predictors of seropositivity in-cluded non-smokers(aOR=1.817;95%CI:1.407-2.346,p=0.000),having blood group A(aOR=1.231;95%CI:1.016-1.493,p=0.034),a history of COVID-19 infection(aOR=2.997;95%CI:2.176-4.127,p=0.000),COVID-19 vaccination(aOR=4.349;95%CI:2.798-6.759,p=0.000),higher crowding index(aOR=1.229;95%CI:1.041-1.451,p=0.015),anosmia and/or ageusia(aOR=3.453;95%CI:2.661-4.481,p=0.000)and history of fever(aOR=1.269;95%CI:1.033-1.560,p=0.023).Healthcare worker and Obesity/overweight were additional significant predictors of seropositivity among the working participants(aOR=1.760;95%CI:1.301-2.381,p=0.000 and aOR=1.384;95%CI:1.059-1.808,p=0.019,respectively).Additional factors showing association with seropositivity in the univariate analysis were:female gender,age group(15-39 years),higher educational level(preparatory and above),lack of environmental disinfection and having roommates at the *** was a positive correlation between the titers of both *** was weakly corre-lated with anti-S titer,while anti-N was significantly correlated with the number of protective measures applied by the *** antibodies were significantly correlated with adult BMI,while both we

关键词： COVID-19 Predictors Seroprevalence Anti-spike Anti-nucleocapsid

Anti-inflammatory and Chemical Composition of Two Plants Family Asteraceae Growing in Saudi Arabia

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Journal of Chemistry and Chemical Engineering 2014年第2期8卷 157-162页

作者： eman Elsharkawy Mona Alshathly mohamed Helal Plant Ecology and Range Department Desert Research Center Cairo 15753 Egypt Chemistry Department Northern Border University Afar 054 Saudi Arabia Zoology Department Northern Border University Arar 054 Saudi Arabia Chemistry Department Northern Border University RaJha 054 Saudi Arabia

The study was designed to investigate the anti-inflammatory and composition of essential oil of two plant family Asteraceae, Achillea fragrantissima and Lactuca serriola growing under dry desert condition. The anti-inflammatory effect of volatile oil extracted by hydrodistillation of plants was studied using carrageenan induced paw edema. Essential oil （100 mg/kg） and （200 mg/kg） were tested the two plant show high inhibition after 4 h, concentration （200 mg/kg） show high inhibition than （100 mg/kg） after 4 h. Sesqui sabinene hydrate, Azuline and u-Bisabolol are the main constituents of the volatile oil were investigated by capillary GC （gas chromatography） and GC-MS （gas chromatography-mass spectrometry）. The discussion shows the role of chemical compound azulene in inflammatory inhibition.

关键词： Achillea fragrantissima Lactuca serriola anti-inflammatory azulene.

Synthesis,antimicrobial, antiquorum-sensing and cytotoxic activities of new series of benzothiazole derivatives

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Chinese Chemical Letters 2015年第12期26卷 1522-1528页

作者： Moustafa T.Gabr Nadia S.El-Gohary eman R.El-Bendary mohamed M.El-Kerdawy Nanting Ni Mona I.Shaaban Department of Medicinal Chemistry Faculty of Pharmacy Mansoura University Department of Chemistry Georgia State University Department of Microbiology Faculty of Pharmacy Mansoura University Department of Microbiology College of Pharmacy Taibah University

New series of benzothiazole derivatives were designed and synthesized. The newly synthesized compounds were screened for their antibacterial activity against Escherichia coli, Staphylococcus aureus and Bacillus cereus. Compounds 6j and 6o showed the highest activity against E. coli and S. aureus. The antifungal activity of these compounds was also tested against Candida albicans and Aspergillus fumigatus293. Compounds 4c, 4g and 6j exhibited the highest activity against C. albicans. In addition, compounds4 a and 6j displayed promising activity against A. fumigatus 293. The same compounds were examined for their antiquorum-sensing activity against Chromobacterium violaceum ATCC 12472, whereas compounds4 a, 6j and 6p showed moderate activity. The in vitro cytotoxicity testing of the synthesized compounds was performed against cervical cancer（Hela） and kidney fibroblast cancer（COS-7） cell lines. Results indicated that all tested compounds have IC50 values 〉50 mmol/L against both cell lines. Molecular properties, toxicities, drug-likeness, and drug score profiles of compounds 4a–c, 5a, 6g,h, 6j, 6l, 6o and7 c,d were also assessed.

关键词： antibacterial moiety antifungal antimicrobial cytotoxic screened moderate substituent Candida albicans

Follow up of Complete Revascularization versus Culprit Revascularization in ST Segment Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention

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World Journal of Cardiovascular Diseases 2019年第12期9卷 930-941页

作者： Ahmed Abdel Aziz Emara mohamed Seleem Hend mohamed abdo Eldeeb mohamed Mahmoud Nawar Department of Cardiology Menoufia University Hospitals Menoufia Egypt Department of Cardiology National Heart Institute Giza Egypt

Objectives: To compare between only Culprit revascularization versus total revascularization in patients with ST-elevation myocardial infarction undergoing primary PCI with 6 months follow up of occurrence of major adverse cardiovascular events (MACCE). Methods: 50 patients were enrolled in this study during the period from 1/11/2018 to 1/11/2019 at Menoufiya University and national heart institute. All patients present with acute ST-elevation myocardial infarction within 24 hours of onset of symptoms, and have multi vessel coronary artery disease on angiography suitable for PCI. Patients were subjected to detailed medical history, physical examination, and electrocardiography. Results: 50 patients with acute ST-elevation myocardial infarction (28 females and 22 males) underwent primary percutaneous coronary intervention. 25 patients had total revascularization to all coronary arteries, the other 25 patients had only culprit revascularization. We found that there was a significant reduction in the incidence of recurrent chest pain and non-fatal Myocardial infarction in the total revascularization group. Conclusion: Our study showed that Multivessel revascularization resulted in an improved clinical course and a significant reduction of MACCE regarding non-fatal MI and a significant reduction of recurrent chest pain.

关键词： Coronary Artery Disease Myocardial Infarction Primary Percutaneous Coronary Intervention Major Cardiovascular Adverse Events

Cocktail of Theileria equi antigens for detecting infection in equines

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Asian Pacific Journal of Tropical Biomedicine 2015年第12期5卷 977-981页

作者： Shimaa Abd El-Salam El-Sayed mohamed abdo Rizk mohamed Alaa Terkawi Ahmed Mousa El Said El Shirbini El Said Gehad Elsayed mohamed Fouda Naoaki Yokoyama Ikuo Igarashi National Research Center for Protozoan Diseases Obihiro University of Agriculture and Veterinary Medicine Department of Biochemistry and Chemistry of Nutrition Faculty of Veterinary Medicine Mansoura University Department of Internal Medicine and Infectious Diseases Faculty of Veterinary Medicine Mansoura University Department of Biochemistry and Chemistry of Nutrition Faculty of Veterinary Medicine Sadat City University

Objective:To use two diagnostic antigens belonging to the frequently associated in Theileria domain,Theileria equi(***)protein 82(Te 82)and *** 104 k Da microneme-rhoptry antigen precursor(Te 43),to diagnose *** infection in horses as compared with equi merozoite antigen-2(EMA-2).Methods:In the current study,we applied a cocktail-ELISA containing two antigens(EMA-2+Te 82)to diagnose *** infection either in experimentally infected horses or in field ***:Our findings have revealed that a cocktail formula of EMA-2+Te 82 provided a more practical and sensitive diagnostic candidate for diagnosing *** infection in horses as compared with Te 82 or Te 43 ***:The ELISA technique using a cocktail formula of EMA-2+Te 82 offers a practical and sensitive diagnostic tool for diagnosing *** infection in horses and using of this promising cocktail formula will be applicable for epidemiological surveys and will help control the infection in horses.

关键词： Theileria equi Equi merozoite antigen-2 Theileria

Quality of Life in Egyptian Children with Cancer

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Journal of Cancer Therapy 2013年第7期4卷 1256-1261页

作者： mohamed Fawzy Mai Saleh mohamed El-Wakil Zeinab Monir eman Eltahlawy Department of Child Health National Research Center Cairo Egypt Department of Clinical Oncology Faculty of Medicine Beni-Suef University Beni-Suef Egypt Department of Environmental and Occupational Medicine National Research Center Cairo Egypt Department of Pediatric Oncology National Cancer Institute Cairo University Cairo Egypt

Background and Objectives: Cancer treatments leading to increased survival rates are reported to participate in the creation of debilitating physical and psychosocial deficits for cancer survivors. Measures of health-related quality of life (HRQOL) are designed to tap such consequences of cancer treatment together with the impact of the disease itself. Methods: Parents of 67 included patients aged 8 - 12 years, were asked to complete the parent proxy report of PedsQLTM 3.0 Cancer Module (Arabic version), as well as a separate sheet for socio-demographic data. Results: The ratio of Males to females was 1.8:1 among study patients with a median age of 8 years at diagnosis. Hematological malignancies represented 70.1% of the sample, with the highest proportion for ALL (52.2%). Total QOL showed to be relatively low with mean value of 62.29 for the whole group. Subscales with least scores were for;worry (44.11), perceived physical appearance (50.6), and procedural anxiety (55.34). On the other hand, the best score was 75.98 for communication, followed by 72.63 for cognitive problems. The impacts of some medical and socio-demographic variables on QOL and its subscales were elicited in our results. Conclusion: Increased treatment intensity, long duration of hospital admission, higher frequency of hospital visits, female sex, younger age at diagnosis, and large family size were all associated with a poorer total QOL and/or its subscales among Egyptian pediatric cancer patients.

关键词： Quality of Life Children Cancer Patients PedsQLTM 3.0 Cancer Module