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Therapeutic interventions of acute and chronic liver disorders:A comprehensive review

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World Journal of Hepatology 2023年第1期15卷 19-40页

作者： Fares em Ali Mostafa K abd el-aziz elham I Sharab Adel G Bakr department of Pharmacology and Toxicology Faculty of PharmacyAl-Azhar UniversityAssiut BranchAssiut 71524Egypt Faculty of Pharmacy Al-Azhar UniversityAssiut BranchAssiut 71524Egypt

Liver disorders are one of the most common pathological problems *** affects more than 1.5 billion *** types of hepatic cells have been reported to be involved in the initiation and propagation of both acute and chronic liver diseases,including hepatocytes,Kupffer cells,sinusoidal endothelial cells,and hepatic stellate cells(HSCs).In addition,oxidative stress,cytokines,fibrogenic factors,microRNAs,and autophagy are also *** the molecular mechanisms of liver diseases leads to discovering new therapeutic interventions that can be used in ***,antioxidant,anti-inflammatory,anti-HSCs therapy,gene therapy,cell therapy,gut microbiota,and nanoparticles have great potential for preventing and treating liver ***,we explored the recent possible molecular mechanisms involved in the pathogenesis of acute and chronic liver ***,we overviewed the recent therapeutic interventions that targeted liver diseases and summarized the recent studies concerning liver disorders therapy.

关键词： Liver disorders Autophagy Gene therapy Anti-hepatic stellate cells Cell therapy

Synthesis of an eco-friendly nanocomposite fertilizer for common bean based on carbon nanoparticles from agricultural waste biochar

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Pedosphere 2021年第6期31卷 923-933页

作者： dina M.SALAMA Mahmoud E.abd el-aziz Mehrez E.el-NAGGAR Essam A.SHAABAN Mohamed S.abd el-WAHEd Vegetable Research department National Research Centre33 El Bohouth StreetDokkiGiza 12622(Egypt) Polymers&Pigments department National Research Centre33 El Bohouth StreetDokkiGiza 12622(Egypt) Textile Research division National Research Centre33 El Bohouth StreetDokkiGiza 12622(Egypt) Pomology department National Research Centre33 El Bohouth StreetDokkiGiza 12622(Egypt) Botany department National Research Centre33 El Bohouth StreetDokkiGiza 12622(Egypt)

The burning of agricultural waste is a major cause of environmental *** this study,we sought to prepare biochar from agricultural waste as a source material for the preparation of carbon nanoparticles(CNPs).Surface morphology,hydrodynamic particle size,and purity and crystallinity of CNPs were extensively investigated using transmission electron microscopy(Tem),zeta sizing,and X-ray diffraction(XRd)spectroscopy,*** CNPs were subsequently immersed in a solution of potassium nitrate(KNO_(3))to prepare a CNPs/NK nanocomposite(CNPs loaded with nitrogen(N)and potassium(K))as a nanocomposite fertilizer for common bean(Phaseolus vulgaris L.).The CNPs/NK nanocomposite was sprayed as a foliar fertilizer at 0,10,20,30,and 40 mg L^(-1) on common bean plants 25 d after sowing on a farm in Shebin el-Kom,el-Monifia,*** growth,yield,and quality of common bean were investigated during two successive growing seasons(2017 and 2018).The highest seed yields of 2.04 and 2.01 t ha^(-1) and the highest values of growth parameters including plant height of 61.5 and 59.2 cm,number of leaves per plant of 35 and 35,number of flowers per plant of 83.3 and 82.7,and plant fresh weight of 148.7 and 152.8 g plant^(-1) were obtained when using the CNPs/NK nanocomposite at a concentration of 20 mg L^(-1) during the 2017 and 2018 growing seasons,respectively.

关键词： foliar fertilizer N and K-loaded nanosized carbon particles Phaseolus vulgaris L. plant growth yield

Zinc and Copper Concentrations in Two Species of Intertidal Crabs from the Middle of the West Coast of Peninsular Malaysia

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湿地科学 2009年第3期7卷 218-229页

作者： Mohammad Mohd Ikram Ahmad Ismail Chee Kong Yap Nor Azwady abd aziz department of Basic Science and Engineering Faculty of Agriculture and Food Sciences Universiti Putra Malaysia Bintulu Sarawak 97008 Malaysia department of Biology Faculty of ScienceUniversiti Putra Malaysia UPM 43400 Serdang Selangor Malaysia

A study on Zn and Cu concentrations in 2 species of intertidal crabs,namely Uca annulipes and dotilla myctiroides collected from the intertidal coastal area of Selangor(5 sites) and Negeri Sembilan(3 sites),west coast of Peninsular Malaysia,was carried *** various localized sources of Zn and Cu discharges towards both the crab species were mentioned.A comparative study between the 2 crab species also revealed that the concentrations of Zn and Cu were significantly(Pd to *** difference was related to the organic matter percentage in the crabs' microhabitat sediments since metals can be associated with the organic matter of sediments in which they might ***(Pdiments when compared to *** sediments for all *** metal and size relationship in the crabs was also *** relationships between Zn and Cu concentrations with body weight and carapace width of *** and *** were significantly(Pd Pelated although the pair wise was weak.

关键词：沉积物马来西亚半岛有机物质螃蟹

Classification of oil palm female inflorescences anthesis stages using machine learning approaches

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Information Processing in Agriculture 2021年第4期8卷 537-549页

作者： Mamehgol Yousefi d.B A.S.Mohd Rafie Samsuzana.abd aziz Syaril Azrad Mohamed Mazmira Mohd Masri Ahmad Shahi O.F.Marzuki department.of Aerospace Engineering Universiti Putra MalaysiaSerdangSelangor 43400Malaysia Smart Farming Technology Research Centre Dept.of Biological and Agricultural EngineeringUniversiti Putra MalaysiaSerdangSelangor 43400Malaysia MPOB Biological Research division Persiaran InstitusiKawasan Institusi Bangi43000 KajangSelangorMalaysia Auckland CBd Auckland 1010New Zealand Faculty of Agriculture and Food Sciences Univesiti Putra Malaysia Bintulu CampusJalan Nyabau97008 Bintulu SarawakMalaysia

Prediction of pollination stages in oil palm plantations is an important research area in precision *** palm is known as the most efficient commercial crop with the capacity to fulfill the growing global demand for vegetable oil ***,oil palm production dependence on pollination is experiencing issues with decreasing the actual ***,alternative methods in commercial plantations such as humanassisted pollination and recently Wireless Sensor Network(WSN)have been deployed despite their high economic costs due to labor *** palm assisted pollination requires precision,inspection,traceability,and validation processes in the ***,all these processes are performed by humans that can be associated with false assumptions,uncertainty,and pollination ***,Machine Learning(ML)approaches as a subset of the Artificial Intelligence(AI)domain provides efficient,cost-effective,and non-destructive solutions to determine these reproductive stages for future autonomous pollination *** goal was to reduce the variability of worker’s performance in oil palms,using ML algorithms to make expert decisions and reduce the risk related to a transient *** comparative empirical study examined and compared the performance of the Random Forest(RF)against k Nearest Neighbor(kNN)and Support Vector Machine(SVM)for classification of oil palm pre-anthesis and anthesis stages,dividing into four classes(1,2,3,and 4).These models were tested using thermal features(endogenous)individually and in combination with meteorological variables(exogenous).The performance of models is evaluated with specific measures of performance,such as overall user’s and producer’s accuracies and F-measure values derived from the confusion *** results showed that the RF model produced better results with regard to average Fmeasure(88.6%,71.83%),producer’s accuracies(88.70%,71.35%),and user’s accuracies(88.27%,72.36%)on test set

关键词： Oil palm Pollination Anthesis stage Machine Learning Classification

Utilization of Small Size Bolti (<i>Talibia nilotica</i>) and Sardine (<i>Sardina pilchardus</i>) Fish in Preparing Canned Weaning Food Purees

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Food and Nutrition Sciences 2021年第7期12卷 719-731页

作者： Faten Farouk abdel-Salam Nadia A. abd-el-aziz Saadia M. Hashem Food Science and Technology department Faculty of Agriculture Alexandria University Alexandria Egypt Meat and Fish Technology Research department Food Technology Research Institute Agriculture Research Center Alexandria Egypt

Utilize small size of bolti and sardine fish in preparing fish based weaning foods rich in protein, essential amino acids, fat high in omega 3 fatty acids, minerals and vitamins was investigated. The proximate composition, nutritional value, physical and sensorial properties were evaluated, The results of the chemical composition showed that the moisture content of fish based weaning food purees ranged from 67.73% to 72.05%. On dry weight basis, the five prepared formulations considered rich in protein (37.39% - 44.86%), fat (26.55% - 30.43%), ash (6.53% - 12.23%) and low in carbohydrates (20.70% - 22.18%). Using fish bones with muscles in preparing weaning food puree caused a marked rise in its content of Ca, P, Fe, and Zn levels especially in purees formulated from bolti. Weaning food purees containing sardine fish rich, in fat, were higher in vitamin A and D than those formulated from bolti one. Palmitic acid (C16:0), stearic acid (C18:0), and myristic acid (C14:0) represented the major saturated fatty acids in the prepared formulations. Weaning food purees containing sardine fish had relatively higher levels of sulfur-dana;">containing amino acids and slight lower values of lysine, alanine and glycine than these including bolti fish. The In vitro protein digestibility index (IVPdI) of the

关键词： Weaning Foods Protein digestibility IVPdI Fish Based Food Products Children Nutrition

New Approach for the Synthesis of Pyrano[2,3-d]- thiazoles

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材料科学与工程（中英文A版） 2011年第5X期1卷 705-710页

作者： Mohamed Sayed abd-elaal elgay Shaban Ibrahim Mohamed Hassan Ahmed Eyada Tarek Ahmed abd-el-aziz Gameel Ahmed Mohamed el-hag All department of Chemistry Faculty of Science Al-Azhar University in Assiut Assiut 71524 Egypt Technology Engineering Institute Tamoh Giza Egypt department of Chemistry Faculty of Science Al-Azhar University Nasr City Cairo Egypt

The structure of 2-carboxamidomethylene-4-thiazolidinone 1 has two active methylene groups: one is endocyclic and close the carbonyl group, where the other is branched at position 2 and close to endocyclic amino group. Thus, the reactivity of compound 1 towards arylidenemalononitrile and ethyl α-cyanocinnamates as electrophiles was studied. Consequently, a new route to the synthesis of pyrano[2,3-d]thiazoles 4a-d and 7a-d has been developed through heterocyclization of carboxamidomethylene -4-thiazolidinone 1 with some α-cyanocinnmonitriles derivatives.

关键词：噻唑啉酮吡喃酮合成氨基酸化合物衍生物羰基环和

Fluid-Structure Interaction in Problems of Patient Specific Transcatheter Aortic Valve Implantation with and Without Paravalvular Leakage Complication

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Fluid dynamics & Materials Processing 2021年第3期17卷 531-553页

作者： Adi Azriff Basri Mohammad Zuber Ernnie Illyani Basri Muhammad Shukri Zakaria Ahmad Fazli abd aziz Masaaki Tamagawa Kamarul Arifin Ahmad department of Aerospace Engineering Universiti Putra MalaysiaSerdang43400Malaysia department of Aeronautical and Automobile Engineering Manipal Institute of TechnologyManipal Academy of Higher EducationManipal576104India department of Medicine Universiti Putra MalaysiaSerdang43400Malaysia department of Biological Function and Engineering Kyushu Institute of TechnologyKitakyushuJapan Fakulti Kejuruteraan Mekanikal Universiti Teknikal Malaysia MelakaHang Tuah Jaya76100Malaysia Aerospace Malaysia Research Center Universiti Putra MalaysiaSerdang43400Malaysia

Paravalvular Leakage(PVL)has been recognized as one of the most dangerous complications in relation to Transcathether Aortic Valve Implantation(TAVI)***,data available in the literature about Fluid Structure Interaction(FSI)for this specific problem are relatively *** the present study,the fluid and structure responses of the hem.dynamics along the patient aorta model and the aortic wall deformation are studied with the aid of numerical simulation taking into account PVL and 100%TAVI valve *** particular,the aorta without valve(AWoV)is assumed as the normal condition,whereas an aorta with TAVI 26 mm for 100%Geometrical Orifice Area(GOA)is considered as the patient aorta with PVL complication.A 3d patient-specific aorta model is elaborated using the MIMICS *** of the identical TAVI valve of Edward SAPIEN XT 26(Edwards Lifes ciences,Irvine,California)is *** undersized 26 mm TAVI valve with 100%valve opening is selected to mimic the presence of PVL at the aortic *** present research indicates that the existence of PVL can increase the blood velocity,pressure drop and WSS in comparison to normal conditions,thereby paving the way to the development of recirculation flow,thrombus formation,aorta wall collapse,aortic rupture and damage of endothelium.

关键词： Paravalvular Leakage(PVL) hem.dynamics transcatheter aortic valve implantation(TAVI) fluid-structure interaction(FSI) edward sapien valve aortic valve(ESV) aortic stenosis(AS)

Analysis and design of UHF Bow-Tie RFId Tag Antenna Input Impedance

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Open Journal of Antennas and Propagation 2016年第2期4卷 85-107页

作者： d. A. abd el-aziz T. G. Abouelnaga E. A. abdallah M. el-Said Yaser S. E. abdo National Institute for Standards Giza Egypt electronics Research Institute Giza Egypt Faculty of Engineering Cairo University Giza Egypt

In this paper two proposed methods of input impedance calculation for Bow-Tie antenna are introduced. The proposed methods show input impedance calculation with high accuracy. Also, design curves for input impedance values were developed depending on the geometry of antenna. The proposed design curves are used to design a Bow-Tie type RFId tag antenna. The input impedance of the tag antenna is calculated using proposed methods and compared with that obtained using CST studio suite 2014 and IE3d Zeland version 12.0 software packages. The results are investigated and discussed. The tag antenna is fabricated, measured and the obtained input impedance is compared with the simulation and the proposed methods. Good agreement among measured input impedance and that simulated by CST, IE3d or proposed methods is obtained.

关键词： Bandwidth Bow-Tie Antenna Radio Frequency Identification (RFId) Ultra High Frequency (UHF)

Evaluation of Inherited Resistance Genes of Bacterial Leaf Blight, Blast and drought Tolerance in Improved Rice Lines

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Rice science 2021年第3期28卷 279-288页

作者： Ibrahim Silas AKOS Mohd Y.RAFII Mohd Razi ISMAIL Shairul Izan RAMLEE Noraziyah abd aziz SHAMSUdIN Asfaliza RAMLI Samuel Chibuike CHUKWU Senesie SWARAY Momodu JALLOH Laboratory of Climate-Smart Food Crop Production Institute of Tropical Agriculture and Food SecurityUniversiti Putra MalaysiaSerdang 43400SelangorMalaysia department of Crop Science Faculty of AgricultureKaduna State University801 KafanchanKaduna 801139Nigeria department of Crop Science Faculty of AgricultureUniversiti Putra MalaysiaSerdang 43400SelangorMalaysia School of Environmental and Natural Resource Sciences Faculty of Science and TechnologyUniversiti Kebangsaan MalaysiaBangi 43600SelangorMalaysia Rice Research Centre Malaysian Agricultural Research and Development InstituteSerdang 43400SelangorMalaysia

Improved rice lines were developed frome three parents with the resistance or tolerance to bacterial leaf blight,blast and drought stress,respectively,using single-,double-and three-way *** improved lines were assessed for agro-morphological and yield traits under non-drought stress(NS)and reproductive-stage drought stress(RS)*** mean comparison of traits measured between parent plants and progenies(improved lines)were similar,and there were significant and non-significant differences among the parents and improved lines(genotypes)under NS and ***,there was significant and non-significant differences in the interaction among both parent varieties and improved lines for NS and *** and 3d-model of principal component analysis did not generate categorical clusters according to crossing methods,and there were no exclusive crossing method inclined variations under the *** improved lines were high-yielding,disease resistant,and drought-tolerant compared with their *** the crossing methods were good for this crop improvement program without preference to any,despite the number of genes introgressed.

关键词： rice bacteria leaf blight blast drought tolerance resistance gene