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Risk Factors for Cardiovascular Disease among Hotel Workers, Bohicon, Benin

Occupational Diseases and Environmental Medicine 2024年第2期12卷 130-141页

作者： Mênonli Adjobimey Rose Mikponhoué eméline Gbaguidi Esdras Hountohotegbè Hélène Sacca Paul Ayélo Vikkey Antoine Hinson Unité de Recherche et d&#8217Enseignement en Sant&#233 au Travail et Environnement FSS Cotonou Cotonou Benin Service de Santé au Travail du Centre National Hospitalier Universitaire de Pneumo Phtisiologie de Cotonou Cotonou Benin Laboratoire d’ Epid&#233miologie des Maladies Chroniques et Neurologiques FSS Cotonou Benin

Introduction: Non-communicable diseases (NCDs) are on the increase in several sectors of activity. The aim of the study was to determine the frequencies of cardiovascular risk factors (CVRF) and factors associated with hypertension among hotel workers in the city of Bohicon. Methods: This was a descriptive and analytical cross-sectional study conducted in the period from December 2018 to January 2019. The variables studied were sociodemographic, occupational, anthropometric and behavioral. Participant recruitment was exhaustive. A standardized questionnaire inspired by the STEPS-WHO questionnaire was used for data collection. After the descriptive analysis, a bivariate analysis was performed using Pearson’s Chi-square test or Fisher’s test at the 5% threshold. Results: A total of 101 workers, 53 (52.47%) of them male, participated in the study. The mean age was 30.60 ± 8.20 years, with extremes of 18 and 55 years. The frequencies of the main risk factors were: 68.32% sitting position > 6 hours/day;38.61% shift work;21.78% high psychological demand, 82.18% low decision latitude, 24.75% low social support, 21.78% occupational stress;7 (6.93%) harmful alcohol consumption;6.93% tobacco consumption;48.51% insufficient physical activity;98.02% insufficient fruit and vegetable consumption;59.41% overweight;14.85% HTA. Factors associated with hypertension were: sex, age and marital status. Conclusion: Occupational factors need to be taken into account when assessing CVRFs. NCD control programs are needed in all sectors of activity. A larger study is needed in the hotel sector.

关键词： FDRCV Occupational Factors Hypertension Hotels Benin

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Relationship between Inter Canine Width and Inter Alar Width, Inter Commissural Width, and Inter Canthal Distance: A Pilot Study

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Open Journal of Stomatology 2024年第6期14卷 279-290页

作者： Grevisse Bindele Ndombolo Augustin Mantshumba Milolo Fidele Nyimi Bushabu em Kalala Kazadi Pierrot Kumpanya Ntumba Jean Marie Kayembe Bukama Elias Lubadi Tshilumba Jean Paul Sekele Isouradi Department of Prosthodontics Teaching Hospital of Kinshasa University Kinshasa Democratic Republic of the Congo National Center of Research in Dental Sciences Kinshasa Democratic Republic of the Congo Department of Oral and Maxillofacial Surgery Teaching Hospital of Kinshasa University Kinshasa Democratic Republic of the Congo Department of Periodontology Teaching Hospital of Kinshasa University Kinshasa Democratic Republic of the Congo Department of Operative Dentistry Teaching Hospital of Kinshasa University Kinshasa Democratic Republic of the Congo

The aim of this study was to determine the relationship between inter canine width (ICW) and inter alar width (IAW), inter commissural width (ICoW), and inter canthal distance (ICaD) in Bantu population. Materials and Methods: It was a pilot study included all participants who were aged at least 18 years, without a history of orthodontics treatment from Prosthodontics Department, Faculty of Dental Medicine, University of Kinshasa. The Ethics committee of the National Center of Research for Dental Sciences in DR Congo approved the study protocol (CNRSB 1504.218). The participants medical records were obtained from the interview and dental examination. Nature of the study was explained with participant information sheet, and an informed consent of all participants was obtained. The inclusion criteria were no missing maxillary and mandibular teeth, no diastema, and no anterior restorations, 18 years old before enrollment in the study. The exclusion criteria were inability to meet the above requirements, pregnancy, and refusal to participate in the study. The inter-canine width (ICW), inter alar width (IAW), inter canthal distance (ICaD) and inter-commissural width (ICoW) of each participant were measured with a digital Vernier caliper (Mitutoyo, UK Ltd.,) (0.01 mm) three times and the average value was recorded. The inter canthal distance (ICaD) was measured without applying pressure by bringing the recording parts of the caliper just in contact with the medial angle. The inter alar width (IAW) was marked with a fine marked pencil on the widest outer surface of the alae of the nose on either side or width. Those two points were measured without applying pressure by bringing the recording parts of the caliper just in contact with the outer surface. The participant was told to stop breathing shortly to avoid any change in shape of the nose. The inter-commissural width (ICoW) was determined by measuring the maxillary lip vermilion from commissure to commissure without the

关键词： Relationship Inter-Canine Width Inter Alar Width Inter Canthal Distance Inter Commissural Width

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Efficient and Accurate Numerical Methods Using the Accelerated Spectral Deferred Correction for Solving Fractional Differential Equations

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Numerical Mathematics(Theory,Methods and Applications) 2022年第4期15卷 876-902页

作者： Xuejuan Chen Zhiping Mao George em Karniadakis School of Science Jimei UniversityXiamen 361021China School of Mathematical Sciences Fujian Provincial Key Laboratory of Mathematical Modeling and High-Performance Scientific ComputingXiamen UniversityXiamenChina Division of Applied Mathematics Brown UniversityProvidenceRI 02912USA

We develop an efficient and accurate spectral deferred correction(SDC)method for fractional differential equations(FDEs)by extending the algorithm in[14]for classical ordinary differential equations(ODEs).Specifically,we discretize the resulted Picard integral equation by the SDC method and accelerate the convergence of the SDC iteration by using the generalized minimal residual algorithm(GMRES).We first derive the correction matrix of the SDC method for FDEs and analyze the convergence region of the SDC *** then present several numerical examples for stiff and non-stiff FDEs including fractional linear and nonlinear ODEs as well as fractional phase field models,demonstrating that the accelerated SDC method is much more efficient than the original SDC method,especially for stiff ***,we resolve the issue of low accuracy arising from the singularity of the solutions by using a geometric mesh,leading to highly accurate solutions compared to uniform mesh solutions at almost the same computational ***,for long-time integration of FDEs,using the geometric mesh leads to great computational savings as the total number of degrees of freedom required is relatively small.

关键词： Stiff problem generalized minimal residual geometric mesh refinement long time evolution fractional phase field models

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Learning two-phase microstructure evolution using neural operators and autoencoder architectures

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npj Computational Materials 2022年第1期8卷 1804-1816页

作者： Vivek Oommen Khem.aj Shukla Somdatta Goswami Rémi Dingreville George em Karniadakis School of Engineering Brown UniversityProvidenceRIUSA Division of Applied Mathematics Brown UniversityProvidenceRIUSA Center for Integrated Nanotechnologies Sandia National LaboratoriesAlbuquerqueNM87185USA

Phase-field modeling is an effective but computationally expensive method for capturing the mesoscale morphological and microstructure evolution in ***,fast and generalizable surrogate models are needed to alleviate the cost of computationally taxing processes such as in optimization and design of *** intrinsic discontinuous nature of the physical phenomena incurred by the presence of sharp phase boundaries makes the training of the surrogate model *** develop a framework that integrates a convolutional autoencoder architecture with a deep neural operator(DeepONet)to learn the dynamic evolution of a two-phase mixture and accelerate time-to-solution in predicting the microstructure *** utilize the convolutional autoencoder to provide a compact representation of the microstructure data in a low-dimensional latent *** DeepONet is trained in the latent space,it can be used to replace the high-fidelity phase-field numerical solver in interpolation tasks or to accelerate the numerical solver in extrapolation tasks.

关键词： materials phase operators

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Fractional Buffer Layers:Absorbing Boundary Conditions for Wave Propagation

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Communications in Computational Physics 2022年第2期31卷 331-369页

作者： Min Cai Ehsan Kharazmi Changpin Li George em Karniadakis Department of Mathematics Shanghai University99 Shangda RoadShanghai 200444P.R.China Division of AppliedMathematics Brown University170 Hope StProvidenceRI 02906USA School of Engineering Brown University184 Hope StProvidenceRI 02912USA

We develop fractional buffer layers(FBLs)to absorb propagating waves without reflection in bounded *** formulation is based on variable-order spatial fractional *** select a proper variable-order function so that dissipation is induced to absorb the coming waves in the buffer layers attached to the *** particular,we first design proper FBLs for the one-dimensional one-way and two-waywave ***,we extend our formulation to two-dimensional problems,wherewe introduce a consistent variable-order fractionalwave *** each case,we obtain the fully discretized equations by employing a spectral collocation method in space and Crank-Nicolson or Adams-Bashforth method in *** compare our results with a finely tuned perfectly matched layer(PML)method and show that the proposed FBL is able to suppress reflected waves including corner reflections in a two-dimensional rectangular *** also demonstrate that our formulation is more robust and uses less number of equations.

关键词： Variable-order fractional derivatives FBL wave equation

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A first look at communication theory / em Griffin ; special consultant, Glen McClish. 4th ed.

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2000年

作者： em Griffin special consultant Glen McClish.

来源：畅想之星图书光盘版（南... 评论

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Therapeutic interventions of acute and chronic liver disorders:A comprehensive review

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World Journal of Hepatology 2023年第1期15卷 19-40页

作者： Fares em.ali Mostafa K Abd El-Aziz Elham I Sharab Adel G Bakr Department of Pharmacology and Toxicology Faculty of PharmacyAl-Azhar UniversityAssiut BranchAssiut 71524Egypt Faculty of Pharmacy Al-Azhar UniversityAssiut BranchAssiut 71524Egypt

Liver disorders are one of the most common pathological problems *** affects more than 1.5 billion *** types of hepatic cells have been reported to be involved in the initiation and propagation of both acute and chronic liver diseases,including hepatocytes,Kupffer cells,sinusoidal endothelial cells,and hepatic stellate cells(HSCs).In addition,oxidative stress,cytokines,fibrogenic factors,microRNAs,and autophagy are also *** the molecular mechanisms of liver diseases leads to discovering new therapeutic interventions that can be used in ***,antioxidant,anti-inflammatory,anti-HSCs therapy,gene therapy,cell therapy,gut microbiota,and nanoparticles have great potential for preventing and treating liver ***,we explored the recent possible molecular mechanisms involved in the pathogenesis of acute and chronic liver ***,we overviewed the recent therapeutic interventions that targeted liver diseases and summarized the recent studies concerning liver disorders therapy.

关键词： Liver disorders Autophagy Gene therapy Anti-hepatic stellate cells Cell therapy

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Extrapolation-Based Acceleration of Iterative Solvers:Application to Simulation of 3D Flows

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Communications in Computational Physics 2011年第3期9卷 607-626页

作者： Leopold Grinberg George em Karniadakis Division of Applied Mathematics Brown UniversityProvidence 02912USA

We investigate the effectiveness of two extrapolation-based methods aiming to approximate the initial state required by an iterative solver in simulations of unsteady flow *** methods lead to about a ten-fold reduction in the iteration count while requiring only negligible computational *** are particularly suitable for parallel computing since they are based almost exclusively on data stored locally on each *** has been evaluated in simulations of turbulent flow in a stenosed carotid artery and also in laminar flow in a very large domain containing the human intracranial arterial tree.

关键词： High-order methods POD CFD low-energy preconditioner

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A Scalable Domain Decomposition Method for Ultra-Parallel Arterial Flow Simulations

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Communications in Computational Physics 2008年第10期4卷 1151-1169页

作者： Leopold Grinberg George em Karniadakis Division of Applied Mathematics Brown UniversityProvidence 02912USA

Ultra-parallel flow simulations on hundreds of thousands of processors require new multi-level domain decomposition *** we present such a new two-level method that has features both of discontinuous and continuous Galerkin ***,at the coarse level the domain is subdivided into several big patches and within each patch a spectral element discretization(fine level)is *** interface conditions for the Navier-Stokes equations are developed to connect the patches,relaxing the C0 continuity and minimizing data transfer at the patch *** perform several 3D flow simulations of a benchmark problem.and of arterial flows to evaluate the performance of the new method and investigate its accuracy.

关键词： Bioflows spectral elements discontinuous Galerkin parallel computing

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Predicting the aquatic risk of realistic pesticide mixtures to species assemblages in Portuguese river basins

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Journal of Environmental Sciences 2015年第5期27卷 12-20页

作者： emília Silva Michiel A.Daam Maria José Cerejeira Centro de Engenharia dos Biossistemas (CEER) Instituto Superior de Agronomia (ISA) University of Lisbon (UL) Tapada da Ajuda1349-017 Lisbon Portugal

Although pesticide regulatory tools are mainly based on individual substances, aquatic ecosystems are usually exposed to multiple pesticides from their use on the variety of crops within the catchment of a river. This study estimated the impact of measured pesticide mixtures in surface waters from 2002 and 2008 within three important Portuguese river basins（＇Mondego＇, ＇Sado＇ and ＇Tejo＇） on primary producers, arthropods and fish by toxic pressure calculation. Species sensitivity distributions（SSDs）, in combination with mixture toxicity models, were applied. Considering the differences in the responses of the taxonomic groups as well as in the pesticide exposures that these organisms experience, variable acute multi-substance potentially affected fractions（ms PAFs） were obtained. The median msP AF for primary producers and arthropods in surface waters of all river basins exceeded 5%, the cut-off value used in the prospective SSD approach for deriving individual environmental quality standards. A ranking procedure identified various photosystem II inhibiting herbicides, with oxadiazon having the relatively largest toxic effects on primary producers, while the organophosphorus insecticides, chlorfenvinphos and chlorpyrifos, and the organochloride endosulfan had the largest effects on arthropods and fish, respectively. These results ensure compliance with European legislation with regard to ecological risk assessment and management of pesticides in surface waters.

关键词： Pesticides Mixtures Risk assessment Multi-substance potentially affected fraction Surface waters

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