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Seropositivity for Hepatitis B Virus, Vaccination Status and Response to Vaccine in a Cohort of Dental Students

Open Journal of Preventive Medicine 2017年第2期7卷 32-39页

作者： Monica Lamberti elpidio maria garzillo maria Rosaria Muoio Antonio Arnese Albert Nienhaus Elia Abbondante Gabriella Di Giuseppe Paola Pedata Alfredo De Rosado Department of Experimental Medicine Section of Hygiene Occupational Medicine and Forensic Medicine Second University of Naples Naples Italy Institute for Health Services Research in Dermatology and Nursing University Medical Center Hamburg-Eppendorf Hamburg Germany Institution for Statutory Accident Insurance and Prevention in Healthcare and Welfare Services Hamburg Germany ASL Napoli 1 Naples Italy Department of Orthodontics Second University of Naples Naples Italy

Background: The development of a vaccine against hepatitis B virus (HBV) has been a major achievement in terms of prevention of HBV infection. To evaluate the immunological status against HBV of dental-profession students, we analysed the long-term immunogenicity and effectiveness of HBV vaccination in Italian dental students with different work seniorities, determining the influence of epidemiological variables on the immune response. Methods: This study, carried out from January 2014 to April 2016, involved 361 under- and post-graduate dental students attending the Second University of Naples. HBV serum markers were determined and multivariate logistic regression analysis was used to identify factors associated with the level of long-term immunogenicity. Results: Of the 361 subjects evaluated, 15 (4.2%) declared no history of vaccination. All vaccinated subjects were HBsAg/anti-HBc negative, with 86 (24.9%) having an anti-HBs titre <10 IU/L. The latter were younger, more likely to be attending undergraduate dental school, and more likely to have been vaccinated in infancy. Conclusion: The findings of this study suggest that assessment of HBV serum markers in workers potentially exposed to hospital infections is useful to identify small numbers of unvaccinated subjects or vaccinated subjects with low antibody titre, all of whom should be referred for a booster series of vaccinations.

关键词： HBV Infection HBV Vaccination Anti-HBs Titre Dental Students

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Massive Thromboembolism from an Abdominal Aortic Aneurysm after Successful Thrombolysis for an Acute Myocardial Infarction

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Case Reports in Clinical Medicine 2015年第2期4卷 45-49页

作者： Fernando Luiz de Melo Bernardi Paulo Cury Rezende Cibele Larrosa garzillo Eduardo Gomes Lima Diogo Arantes Behling Pereira da Luz Vera Demarchi Aiello Whady Hueb Department of Atherosclerosis Heart Institute of the University of Sao Paulo Sao Paulo Brazil Department of Pathology Heart Institute of the University of Sao Paulo Sao Paulo Brazil

Thrombolytic therapy is indicated to the treatment of patients with ST-elevation myocardial infarction or pulmonary embolism. Its indication should especially consider the risk of bleeding, but other complications might pose harm to patients. Although rarely reported, fibrinolysis can trigger thromboembolic phenomena from emboligenic sources such as aortic aneurysms. Clinicians should be aware of this life-threatening complication. In this case report, we present one patient admitted due to a ST-segment elevation acute myocardial infarction successfully treated with fibrinolytic treatment, but who evolved with a massive microembolism from an abdominal aortic aneurysm. Despite intensive medical care, the patient evolved with multiorganic failure due to distal microembolism to the guts and lower limbs, severe rhabdomyolysis and ultimately to death. In this challenging case, clinical, anatomical and histopathologic features are presented and discussed.

关键词： Thromboembolism Abdominal Aortic Aneurysm Fibrinolysis Myocardial Infarction

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乳腺成像时偶然发现椎体骨折:MR定位像的潜在价值

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国际医学放射学杂志 2013年第1期 93-94页

作者： A.Bazzocchi P.Spinnato G.garzillo F.Ciccarese U.Albisinni S.Mignani 赵健仪 Imaging Division Clinical Department of Radiological and Histocytopathological SciencesSant'Orsola-Malpighi HospitalUniversity of BolognaVia Massarenti 940138 BolognaItaly

目的偶然发现椎体骨折是评价骨骼健康情况的关键因素。该研究目的是回顾性评价乳腺MRI的定位像作为显示骨质疏松性椎体骨折的潜在价值。方法 3位肌骨放射学专家采用半定量方法回顾性分析了856例乳腺MRI的矢状定位像以发现椎体骨折。同... 详细信息

目的偶然发现椎体骨折是评价骨骼健康情况的关键因素。该研究目的是回顾性评价乳腺MRI的定位像作为显示骨质疏松性椎体骨折的潜在价值。方法 3位肌骨放射学专家采用半定量方法回顾性分析了856例乳腺MRI的矢状定位像以发现椎体骨折。同时研究病人的病史和基本信息。回顾正式的乳腺MRI与既往的影像学检查,以确定病人病史中是否有椎体骨折或其他相关骨病的情况。结果 856例病人[21～89岁,平均(54.7±12.2)岁]中,780例(91.1%)由于肿瘤原因而进行MRI检查,76例(8.9%)由于非肿瘤因素而参与本研究;57例的MRI定位像不能达到诊断要求而被排除。剩余799例中,71例(8.9%)MRI定位像中发现椎体骨折。其中63例(88.7%)的椎体骨折在影像学报告和既往病史中均未提到(P<0.001)。任何乳腺报告中都没有提到椎体骨折。4例病人的MRI定位像中发现了椎体转移瘤。结论系统评价MRI定位像能够获得额外的临床信息,以防止漏诊椎体骨折。在其他影像学检查时,MRI定位像可用于椎体骨折的筛查。

关键词：定位像 MRI 乳腺乳房椎体骨折 MR 潜在价值

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