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Growth and Photosynthetic Pigments of Cotton Cultivars Irrigated with Saline Water

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Agricultural Sciences 2019年第1期10卷 81-91页

作者： elka costa santos nascimento Ronaldo do nascimento André Alisson Rodrigues da Silva Carlos Vailan de Castro Bezerra Mateus costa Batista Luana Lucas de Sá Almeida Veloso Márcia Cristina de Araújo Pereira Hallyson Oliveira Federal University of Campina Grande Campina Grande Brazil

The cultivation of cotton is a relevant socioeconomic activity in the Brazilian agricultural scenario. In the Brazilian Northeast, however, production is limited by low rainfall, requiring water supplementation, a problem for the cotton cultivation practiced in the semi-arid region, due to the presence of saline ions in several water sources, from where the water is used for irrigation. It is necessary to identify cultivars that better tolerate saline stress in order to provide subsidies for their cultivation under such conditions. In this sense, the objective was to evaluate the tolerance of cotton cultivars to salinity. The experiment was conducted in a greenhouse, belonging to the Natural Resource Technology Center of the Federal University of Campina Grande, Campus I, Campina Grande, Brazil, in a completely randomized design in a 2 × 5 factorial scheme, with four replications, totaling 40 experimental units (BRS 368 RF and BRS SAFIRA) submitted to five saline levels (1.5, 3.0, 4.5, 6.0 and 7.5 dS·mˉ1). Irrigation with water saline of EC from 1.5 dS·mˉ1 affects adversely the growth of cotton cultivars, causing reductions in plant height, stem diameter, leaf area and number of leaves. Saline stress reduced the levels of the photosynthetic pigments of the cotton plants studied.

关键词： Gossypium hirsutum L. Salinity Chlorophyll

Fluid-dynamics evaluation in a conical spouted bed and characterization of foxtail millet seeds

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Particuology 2015年第6期13卷 75-81页

作者： Lidiane Diniz do.nascimento Lorena Gomes Corumba Sandra Cristina dos santos Rocha Osvaldir Pereira Taranto Cristiane Maria Leal costa Lenio Jose Guerreiro de Faria Federal University of Pard Faculty of Chemical Engineering Laboratory of Drying and Particle Coating Augusto Correa Street w/n 66075-110 BelemPA Brazil University of Campinas School of Chemical Engineering. Albert Einstein Avenue 500 13083-852 Campinas $8o Paulo Brazil

Foxtail millet （Setaria italica） is one of the most valuable species in economic terms in the genus Setaria and plays an important role in human nutrition, animal feed, and agriculture. The present study described chemical, physical, and quality aspects of seeds of foxtail millet. Furthermore, the fluid-dynamic behavior of the seeds was evaluated in a conical spouted bed, which has advantages in terms of promoting the cyclic and regular movement of the seed particles. Dynamic parameters of spouting （minimum spouting veloc- ity, stable and peak pressure drop） were determined and compared with those obtained from empirical correlations available in the literature. The results obtained from physical characterization showed that the seeds can be classified as belonging to Group D of Geldart, having a non-rough surface, mean diameter of 1.75 mm, and sphericity of 0.74. Fluid-dynamics analysis showed that the seeds are suitable for processing in a spouted bed, which is in agreement with the results of particle physical characterization.

关键词： Foxtail millet Parameters of spouting Characterization Conical spouted bed

Chemical and microbiological characterization of tinctures and microcapsules loaded with Brazilian red propolis extract

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Journal of Pharmaceutical Analysis 2017年第5期7卷 280-287页

作者： Erika Tayse da Cruz Almeida Maria Cristina Delgado da Silva José Marcos dos santos Oliveira Regianne Umeko Kamiya Rodolfo Elleson dos santos Arruda Danilo Abreu Vieira Valdemir da costa Silva Pierre Barnabé Escodro Irinaldo Diniz Basílio-Júnior Ticiano Gomes do nascimento Laboratório de Controle de Qualidade e Análise de Fármacos Medicamentos e AlimentosCurso de FarmáciaEscola de Enfermagem e FarmáciaUniversidade Federal de AlagoasCampus A.C.SimõesBR 104 Norte-Km 97MaceióAL.CEP:57072-970Brazil Laboratório de Controle de Qualidade Microbiológico de Alimentos Faculdade de NutriçãoUniversidade Federal de AlagoasCampus A.C.SimõesBR 104 Norte/Km 97MaceióAL.CEP:57072-970Brazil

The aim of this study was to characterize tinctures and microcapsules loaded with an ethanol extract of red propolis through chemical, physicochemical and microbiological assays in order to establish quality control tools for nutraceutical preparations of red propolis. The markers(isoflavonoids, chalcones, pterocarpans,flavones, phenolic acids, terpenes and guttiferones) present in the tinctures A and B were identified and confirmed using LC/ESI/FTMS/Orbitrap. Four compositions(A, B, C and D) were prepared to contain B tincture of the red propolis with some pharmaceutical excipients and submitted to two drying processes, i. ***-drying and freeze-drying to obtain microcapsules loaded with the red propolis extract. The tinctures and microcapsules of the red propolis were submitted to the total flavonoid content and antioxidant activity *** antibacterial activity and minimum inhibitory concentration(MIC) were tested using Staphylococcus aureus ATCC 25293 and Pseudomonas aeruginosa ATCC 27853 strains. The tinctures and microcapsules presented high flavonoid quantities from 20.50 to 40.79 mg/100 mg of the microcapsules. The antioxidant activity and IC50 were determined for the tinctures A and B(IC50: 6.95 μg/m L and 7.48 μg/m L), the spray-dried microcapsules(IC50: 8.89–15.63 μg/m L) and the freeze-dried microcapsules(IC50: 11.83–23.36 μg/m L). The tinctures and microcapsules were proved to be bioactive against gram-positive and gram-negative bacteria with inhibition halos superior to 10 mm at concentration of 200 μg/m L and MIC values of 135.87–271.74 μg/m L using gram-positive strain and 271.74–543.48 μg/m L using gram-negative strain. The tinctures and microcapsules of the red propolis have a potential application for nutraceutical products.

关键词： Red propolis Tinctures Microcapsules Isoflavonoids LC/ESI/FTMS/Orbitrap Antioxidant activity Antibacterial activity

Changes in calcium accumulation and utilization efficiency and their impact on recycling,immobilization,and export across the oil palm cycle

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Oil Crop Science 2024年第3期9卷 143-150页

作者： Ismael de Jesus Matos Viégas Luma Castro de Souza Eric Victor de Oliveira Ferreira Milton Garcia costa Glauco André dos santos Nogueira Vitor Resende do nascimento Candido Ferreira de Oliveira Neto Capanema Campus Federal Rural University of the Amazon(UFRA)Av.Barao de CapanemaCaixa D'agua5514-6434ParaBrazil Center of Agricultural and Environmental Sciences Federal University of Maranhao(UFMA)ChapadinhaBR-222km 04SNBoa Vista65500000MaranhaoBrazilc Capitao Poço Campus Federal Rural University of the Amazon(UFRA)Tv.Pau AmareloS/n-Vila Nova68650-000Capitao PoçoParaBrazil Department of Soil Science Sao Paulo State University(Unesp)School of Agricultural and Veterinarian SciencesJaboticabalVia de Acesso Prof.Paulo Donato CastelaneCastellane-S/N-Vila Industrial14884-900Sao PauloBrazil Institute of Agricultural Sciences(ICA) Federal Rural University of the Amazon(UFRA)Estr.Principal da Ufra2150Curio-Utinga66077-580BelemParaBrazil

Effective calcium(Ca)management is crucial for optimizing oil palm cultivation and enhancing crop *** study aimed to gain insights into the dynamics of Ca concentration,accumulation,exportation,immobilization,and recycling in various oil palm organs relative to plant *** experiment was conducted at the Agropalma enterprise site in the northeastern region of Para State,Brazil,evaluating seven plant age treatments:2,3,4,5,6,7,and 8 years *** a completely randomized design with four *** results demonstrated an age-related increase in Ca concentration in petioles,rachis,arrows,male inflorescences,peduncles,and ***,Ca accumulation exhibited an upward trend in all organs with progressing plant ***,the study revealed an enhanced Ca use efficiency across all plant organs in correlation with the age of oil palm *** findings underscore the dynamic nutritional demands of oil palm,influencing Ca immobilization,cycling,and export throughout its developmental stages.

关键词： Elaeis guineensis Jacq Ca cycling Ca export Ca immobilization Ca use efficiency Plant nutrition Amazon

HPLC-DAD analysis and antifungal effect of Hyptis martiusii Benth(Lamiaceae) against Candida strains

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Asian Pacific Journal of Tropical Biomedicine 2019年第3期9卷 123-128页

作者： Janaína Esmeraldo Rocha Henrique Douglas Melo Coutinho Cícero Roberto nascimento Saraiva Antonia Thassya Lucas dos santos Ant?nio Judson Targino Machado Jo?o Tavares Calixto Júnior Irwin Rose Alencar Menezes José Galberto Martins da costa Jaime Ribeiro-Filho Aracelio Viana Colares Laboratory of Microbiology and Biology Molecular Department of Biological Chemistry Regional University of Cariri Leao Sampaio University Center Department of Biological Sciences Regional University of Cariri Laboratory of Pharmacology and Molecular Chemistry Department of Biological Chemistry Regional University of Cariri Laboratory of Natural Product Research Department of Biological Chemistry Regional University of Cariri

Objective: To evaluate the anti Candida activity of Hyptis martiusii decoction and its major compound, caffeic acid alone or in the presence of fluconazole, as well as their cytotoxic effect. Methods: The decoction was characterized using high performance liquid chromatography coupled with diode array detector. For the antifungal activity, the minimum inhibitory concentration(MIC) and the potential effect of the decoction with the fluconazole were evaluated by microdilution method using 96-well microtiter trays. The osmotic fragility test was performed using erythrocytes under saline stress. All tests were performed in triplicate. Results: The chemical characterization of the decoction was performed by high performance liquid chromatography and revealed the presence of seven compounds, including caffeic acid as major constituent. The antifungal tests demonstrated that both decoction(DHm) and caffeic acid obtained from Hyptis martiusii presented MIC and MFC ≥4096 μg/mL against Candida albicans and Candida tropicalis strains. However, in the presence of fluconazole, DHm and caffeic acid presented IC_(50) of 2.60 and 2.53 μg/mL respectively, demonstrating significant synergistic effects against Candida strains. The modulator activity of DHm might be due to the presence of caffeic acid. Moreover, DHm and caffeic acid did not cause significant hemolytic effects, indicating that they present low cytotoxicity. Conclusions: These data indicate that DHm potentiates the activity of the fluconazole, without enhancement of the toxicity, encouraging further toxicological, pharmacological and phytochemical studies to provide consistent evidence of the potential of this plant to be used in drug development.

关键词： Hyptis martiusii Caffeic acid Candida albicans Candida tropicalis Antifungal properties

Central depressant effects of Piper tuberculatum Jacq essential oil in mice

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Food Bioscience 2022年第4期48卷 620-629页

作者： Valterlúcio dos santos Sales Francisco Romero Cabral Emmily Petícia do nascimento Sales Tatyelle Bezerra Carvalho Maria Haiele Nogueira costa Victor Afonso Pereira de Oliveira Cristina Kelly de Souza Rodrigues Francisco Rodolpho Sobreira Dantas Nobrega de Figueiredo Daniel Souza Bezerra Gyllyandeson de Araújo Delmondes Henrique Douglas Melo Coutinho Jose Galberto Martins da costa Irwin Rose Alencar de Menezes Cícero Francisco Bezerra Felipe Marta Regina Kerntopf Universidade Regional do Cariri Departamento de Química Biol´ogicaCratoCear´aBrazil Universidade Federal de S˜ao Paulo-Departamento de Fisiologia S˜ao PauloSPBrazil Faculdade de Ciˆencias M´edicas da Santa Casa de S˜ao Paulo S˜ao PauloSPBrazil Universidade Federal da Paraíba Departamento de Biologia MolecularJo˜ao PessoaParaíbaBrazil

This study aims to investigate the toxicity and possible effects and mechanism of action of the essential oil obtained from the Piper tuberculatum Jacq.‘s fruit(EOPT)on the central nervous system(CNS)of *** the Hippocratic test,it was observed ambulation reduction,sedation,piloerection and mortality of 25%at the dose of 1000 mg/kg and 50%at the dose of 5000 mg/*** results found demonstrate that the EOPT is endowed with a possible depressant effect,and is characterized by a likely sedative(open field test),anxiolytic-like(elevated plus maze test),anticonvulsant(pentylenetetrazole-induced seizure test)and hypnotic action(pentobarbital-induced sleeping time).These effects may possibly occur due to the interaction between the monoterpenes,present in its essential oil,and the GABAergic pathway confirmed by reversion of the effects by ***,these results demonstrate the therapeutic potential and the validation of the ethnopharmacological use of this species in the treatment of disorders affecting the central nervous system.

关键词： Piper tuberculatum Jacq. Essential oil Sedative Anxiolytic Hypnotic

Revealing the kinetics of Leishmania chagasi infection in the male genital system of hamsters

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Infectious Diseases of Poverty 2016年第1期5卷 261-265页

作者： Amanda P.N.Quintal Bruna C.Borges Paula C.Brígido Rebecca T.Silva Ana F.Notário Marlus A.santos Maria A.de Souza Fernanda G.O.nascimento Antônio V.Mundim Guilherme M.J.costa André B.Vasconcelos Claudio V.da Silva Instituto de Ciências Biomédicas Universidade Federal de UberlândiaUberlândiaMinas GeraisBrasil Hospital Veterinário Universidade Federal de UberlândiaUberlândiaMinas GeraisBrasil Departamento de Ciências Biomédicas Universidade Federal de Minas GeraisBelo HorizonteBrasil Universidade de Uberaba UberabaMinas GeraisBrasil Departamento de Imunologia–Instituto de Ciências Biomédicas Universidade Federal de UberlândiaCampus UmuaramaUberlândiaMGBrasil

Background:Leishmaniasis causes alterations and lesions in the genital system,which leads to azoospermia and testicular atrophy in animals during the chronic phase of the *** aim of this study was to reveal the kinetics of Leishmania chagasi infection in the genital system of male golden hamsters(Mesocricetus auratus).Methods:Animals were intraperitoneally inoculated with amastigotes from *** different time points animals were euthanized and genital organs processed for histo-pathological,qPCR,cytokines and testosterone detection ***:Our results showed a high parasite load in testis,followed by an increase of pro-inflammatory cytokines IL1-β,TNF-αand IFN-γ,and ***,IL-4 expression was upregulated and basal parasite persistence in testis was observed using the experimental ***:Extracellular amastigotes migrated to the epididymis posing as a potential major factor of parasite persistence and venereal transmission of *** infection in hamsters.

关键词： Leishmania chagasi Extracellular amastigotes Testis Epididymis Immune response Testosterone

Individual and Combined Effects of the Extractant,Surfactant and Modifier Concentrations on the Droplet Coalescence Time of the Primary Emulsion in the Liquid Surfactant Membrane Extraction Process

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Advances in Chemical Engineering and Science 2018年第4期8卷 205-214页

作者： Adriane Salum Lorena da costa nascimento Tania Lúcia santos Miranda Leandro Dornellas Sampaio Andrade Cibele Konzen Julio Cézar Balarini Estevao Magno Rodrigues Araújo Fabrício Eduardo Bortot Coelho Department of Chemical Engineering Federal University of Minas GeraisBelo HoriozonteBrazil

In this work, the individual and combined effects of the extractant, surfactant and modifier concentrations on the droplet coalescence time of the primary emulsion in the liquid surfactant membrane extraction process were evaluated, through emulsification experiments. Adogen 464 was used as extractant (carrier), and Escaid 110, as diluent. Two systems were studied. The first one composed by the extractant, the surfactant and the diluent, and the second one composed by the same reagents, but with the addition of 1-decanol as modifier. It was observed that, when the modifier is not present in the membrane phase, the surfactant not only stabilizes the primary emulsion, but, apparently, it also plays a role similar to that of the alcohol, promoting the solvation of the amine in a low polarity diluent. Furthermore, the extractant, a quaternary amine, helps to stabilize the primary emulsion in systems without a modifier. For membrane phases consisting of 1 or 5% w/w of Adogen 464 and 2% or 5% w/w of ECA 4360, a concentration of 3% w/w of 1-decanol was sufficient to promote the solvation of Adogen 464 in Escaid 110 and to obtain a low droplet coalescence time.

关键词： Liquid Surfactant Membranes Emulsification Adogen 464 ECA 4360 1-Decanol Droplet Coalescence Time

Crohn's disease and clinical management today:How it does?

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World Journal of Methodology 2023年第5期13卷 399-413页

作者： Ronaldo Teixeira da Silva Júnior Jonathan santos Apolonio Jessica Oliveira de Souza nascimento Bruna Teixeira da costa Luciano Hasimoto Malheiro Marcel Silva Luz Lorena Sousa de Carvalho Cleiton da Silvasantos Fabrício Freire de Melo Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil

Crohn’s Disease(CD)is an Inflammatory Bowel Disease and is characterized by an immune-mediated *** etiology results from the interaction between genetic,enviromental and microbial *** pathophysiology,it involves high levels of interleukin(IL)-12,IL-17,and Th1 profile,along with loss of tolerance mechanisms,an increase in pro-inflammatory interleukins,beyond the possibility to affect any part of the gastrointestinal *** symptoms include abdominal pain,chronic diarrhea,weight loss,anorexia,and fatigue,as well as blood in the stool or ***,conditions comprising musculoskeletal,cutaneous,ocular,hepatic,and hematological alterations may be associated with this scenario and extra-intestinal presentation,such as erythema nodosum,anterior uveitis,osteoporosis,and arthritis can also ***,clinical history,exams as fecal calprotectin,ileocolonocopy,and capsule endoscopy can be performed in the diagnosis investigation,along with treatments to induce and maintain *** this sense,anti-inflammatory drugs,such as corticosteroids,immunomodulators,and biological agents,as well as surgery and non-pharmacological interventions plays a role in its *** aim of this review is to bring more current evidence to clinical management of CD,as well as to briefly discuss aspects of its pathophysiology,surveillance,and associated disorders.

关键词： Crohn's disease Inflammatory bowel diseases Diagnosis Treatment Immunomodulation Biological agents