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Dynamics and origin of cytokinins involved in plant manipulation by a leaf-mining insect

Insect Science 2017年第6期24卷 1065-1078页

作者： Hui Zhang Antoine Guiguet Geraldine Dubreuil Anna Kisiala Peter Andreas R. J. Neil Emery elisabeth huguet Melanie Body David Giron Institut de Recherche sur la Biologie de I'lnsecte UMR 7261 CNRSIUniversite Francois-Rabelais de Tours Tours France Departement de Biologie Ecole Normale Superieure de Lyon Lyon France Department of Life and Environmental Sciences Kyoto Prefectural University Kyoto Japan Department of Biology Trent University Peterborough Canada Division of Plant Sciences Christopher S. Bond Life Sciences Center University of Missouri Columbia USA

Several herbivorous insects and plant-associated microorganisms control the phytohormonal balance, thus enabling them to successfully exploit the plant by inhibiting plant defenses and withdrawing plant resources for their own benefit. The leaf-mining moth Phyllonorycter blancardella modifies the cytokinin （CK） profile of mined leaf-tissues, and the insect symbiotic bacteria Wolbachia is involved in the plant manipulation to the benefit of the insect host. To gain a deeper understanding into the possible origin and dynamics of CKs, we conducted an extensive characterization of CKs in larvae and in infected apple leaves. Our results show the enhanced CK levels in mines, both on green and yellow leaves, allowing insects to control their nutritional supply under fluctuating environmental conditions. The spatial distribution of CKs within the mined leaves shows that hormone manipulation is strictly limited to the mine suggesting the absence of CK translocation from distant leaf areas toward the insect feeding site. Mass spectrometry analyses reveal that major CK types accumulating in mines and larvae are similar to what is observed for most gall-inducers, suggesting that strategies underlying the plant manipulation may be shared between herbivorous insects with distinct life histories. Results further show that CKs are detected in the highest levels in larvae, reinforcing our hypothesis that CKs accumulating in the mines originate from the insect itself. Presence of bacteria- specific methylthio-CKs is consistent with previous results suggesting that insect bacterial symbionts contribute to the observed phenotype. Our study provides key findings toward the understanding of molecular mechanisms underlying this intricate plant-insect-microbe interaction.

关键词： cytokinins insect bacterial symbionts leaf-miners phytohormones plantinsect-microbe interactions plant manipulation

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3-Dimensional Skew-symmetric Algebras and the Variety of Horn-Lie Algebras

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Algebra Colloquium 2018年第4期25卷 547-566页

作者： elisabeth Remm LMIA Universite de Hante-A1sace (LMIAEA 3993)F-68100 MulhouseFrance

An algebra is called skew-symmetric if its multiplication operation is a skew-symmetric bilinear *** determine all these algebras in dimension 3 over a field of characteristic different from *** an application,we dete... 详细信息

关键词： 3-dimensional skew-symmetric algebras variety of Hom-Lie algebras

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Bioengineering liver tissue by repopulation of decellularised scaffolds

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World Journal of Hepatology 2023年第2期15卷 151-179页

作者： Zeeshan Afzal Emmanuel Laurent huguet Department of Surgery Addenbrookes HospitalNIHR Comprehensive Biomedical Research and Academic Health Sciences CentreCambridge University Hospitals NHS Foundation TrustCambridge CB20QQUnited Kingdom

Liver transplantation is the only curative therapy for end stage liver disease,but is limited by the organ shortage,and is associated with the adverse consequences of *** of decellularised whole organ scaffolds with appropriate cells of recipient origin offers a theoretically attractive solution,allowing reliable and timely organ sourcing without the need for *** methodologies vary widely but seek to address the conflicting objectives of removing the cellular component of tissues whilst keeping the 3D structure of the extra-cellular matrix intact,as well as retaining the instructive cell fate determining biochemicals contained *** scaffold recellularisation has progressed from small rodent in vitro studies to large animal in vivo perfusion models,using a wide range of cell types including primary cells,cell lines,foetal stem cells,and induced pluripotent stem *** these models,a limited but measurable degree of physiologically significant hepatocyte function has been reported with demonstrable ammonia metabolism in *** repopulation and function have been restricted by challenges relating to the culture and propagations of cholangiocytes,though advances in organoid culture may help address *** vasculature repopulation has enabled sustainable blood perfusion in vivo,but with cell types that would limit clinical applications,and which have not been shown to have the specific functions of liver sinusoidal endothelial *** cell groups such as Kupffer cells and stellate cells have not been *** by repopulation of decellularised scaffolds has significantly progressed,but there remain significant experimental challenges to be addressed before therapeutic applications may be envisaged.

关键词： Regenerative Bioengineering Scaffolds Liver Decellularisation Recellularisation

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MicroTAS 2011:Microfluidics in Seattle

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Science China Chemistry 2012年第4期55卷 550-551页

作者： VERPOORTE elisabeth Pharmaceutical Analysis Department of Pharmacy University of Groningen Antonius Deusinglaan 1 9713AV Groningen The Netherlands

Though the labonachip or microfluidics field can nov be considered well established and perhaps even maturafter more than two decades, it continues to grow. Type il ＂lab chip＂ or ＂microfluidics＂ into the Web of ScienceTM ant you＇ll see what I mean. At the time of writing this article there were 8029 published items, which had been citer 100,676 times altogether. An astounding number in fact ＂lab chip＂ or ＂microfluidics＂ has an Hindex of 131, asta tistic that many chemists, analytical or otherwise, have con tributed to over the years. The number of published paper continues to increase with each successive year, with mort than 1400 of the 8029 articles mentioned above appearin in 2011 alone. We are offto a good start in 2012, with mort than 150 papers published in January. At this rate, the tota number of papers in 2012 will easily surpass that of 2011 Clearly, more and more researchers continue to enter tht labonachip field, ensuring a healthy and dynamic re search climate internationally.

关键词：微流体西雅图实验室芯片芯片实验室化学家论文 THT

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Genesis and soil environmental implications of intact in-situ rhizoliths in dunes of the Badain Jaran Desert,northwestern China

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Acta Geochimica 2022年第5期41卷 811-822页

作者： Qingfeng Sun Kazem Zamanian Arnaud huguet Omid Bayat Hong Wang Hanan SBadawy Key Laboratory of Resource Environment and Sustainable Development of Oasis Northwest Normal University730070 LanzhouGansu ProvinceGansuPR China Key Laboratory of Eco-function Polymer Materials of the Ministry of Education Northwest Normal University730070 LanzhouGansuPR China Institute of Soil Science Leibniz University of HannoverHerrenhäuser Straße 230419 HannoverGermany Sorbonne Université CNRSEPHEUMR METISF-75005 ParisPSLFrance Department of Soil Science Isfahan University of Technology84156-83111 IsfahanIran Interdisciplinary Research Center of Earth Science Frontier Beijing Normal University100875 BeijingPR China Department of Geology Faculty of ScienceBeni-Suef University62521 Beni-SuefEgypt School of Geographical Sciences Nanjing University of Information Science and Technolog210044NanjingChina

Desert rhizoliths are generally found as weathered,broken and scattered samples on dune field surface,but rarely insitu in their initial states buried under the soil of desert in the Badain Jaran Desert,northwest *** study off ers an assessment of the morphological,mineralogical,and chemical properties of intact and in-situ rhizoliths found in soils of swales and depressions among dune *** characteristics of these rare and precious objects were assessed using optical polarizing microscopy,cathodoluminescence,scanning electronic microscopy,radiocarbon dating,and stable isotopic analyses,providing the opportunity for discussion of the rhizolith formation mechanisms and associated environmental *** and laboratory investigations showed that the in-situ intact rhizoliths were formed only in the places where Artemisia shrubs are living,and the remaining root relicts within rhizoliths belong to this *** spatial distribution of rhizoliths also suggested that low topographic positions on a landscape provided soil moisture,and redox environments favored rhizolith formation.A semi-closed redox environment in the subsoil at swales and depressions,where water is always present,along with the sandy soil texture,facilitated fast water percolation to deeper depths and *** a soil environment not only provides water for Artemisia growth,but also for the weathering of minerals such as felspars and calcite from primary carbonates,and for the decomposition of root ***,harsh climatic conditions,such as strong winds and solar radiation,led to water evaporation through dead root channels and triggered the calcification along the root *** entrapped lithogenic carbonates and to a lesser extent the decomposition of Artemisia roots provided the carbon sources for the rhizoliths formation,while the weathering of soil minerals,particularly feldspars and carbonates,was the main source of *** in the Badain Jaran des

关键词： Rhizoliths Calcification Leptic regosols Artemisia roots Decomposition Soil moisture

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Use of Total Precipitable Water Classification of A Priori Error and Quality Control in Atmospheric Temperature and Water Vapor Sounding Retrieval

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Advances in Atmospheric Sciences 2012年第2期29卷 263-273页

作者： Eun-Han KWON elisabeth WEISZ School of Earth and Environmental Sciences Seoul National University Seoul 151-747 Korea Cooperative Institute for Meteorological Satellite Studies University of Wisconsin-Madison1225 West Dayton Street Madison WI 53706 USA

This study investigates the use of dynamic a priori error information according to atmospheric moistness and the use of quality controls in temperature and water vapor profile retrievals from hyperspectral infrared （IR） sounders. Temperature and water vapor profiles are retrieved from Atmospheric InfraRed Sounder （AIRS） radiance measurements by applying a physical iterative method using regression retrieval as the first guess. Based on the dependency of first-guess errors on the degree of atmospheric moistness, the a priori first-guess errors classified by total precipitable water （TPW） are applied in the AIRS physical retrieval procedure. Compared to the retrieval results from a fixed a priori error, boundary layer moisture retrievals appear to be improved via TPW classification of a priori first-guess errors. Six quality control （QC） tests, which check non-converged or bad retrievals, large residuals, high terrain and desert areas, and large temperature and moisture deviations from the first guess regression retrieval, are also applied in the AIRS physical retrievals. Significantly large errors are found for the retrievals rejected by these six QCs, and the retrieval errors are substantially reduced via QC over land, which suggest the usefulness and high impact of the QCs, especially over land. In conclusion, the use of dynamic a priori error information according to atmospheric moistness, and the use of appropriate QCs dealing with the geographical information and the deviation from the first-guess as well as the conventional inverse performance are suggested to improve temperature and moisture retrievals and their applications.

关键词： atmospheric sounding AIRS total precipitable water a priori error quality control

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Renal dysfunction in cirrhosis: acute kidney injury and the hepatorenal syndrome

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Gastroenterology Report 2017年第2期5卷 127-137,I0002页

作者： Theresa Bucsics elisabeth Krones Division of Gastroenterology and Hepatology Department of Internal Medicine IIIMedical University of ViennaViennaAustria Vienna Hepatic Hemodynamic Laboratory Medical University of ViennaViennaAustria Division of Gastroenterology and Hepatology Department of Internal MedicineMedical University of GrazGrazAustria

Renal dysfunction is a common complication of liver cirrhosis and of utmost clinical and prognostic *** with cirrhosis are more prone to developing acute kidney injury(AKI)than the non-cirrhotic ***-renal AKI,the hepatorenal syndrome type of AKI(HRS-AKI,formerly known as‘type 1’)and acute tubular necrosis represent the most common causes of AKI in *** differentiation is imperative,as treatment differs *** pre-renal AKI usually responds well to plasma volume expansion,HRS-AKI and ATN require different specific approaches and are associated with substantial *** paradigms,such as the threshold of 2.5 mg/dL for diagnosis of HRS-AKI,have recently been abolished and novel urinary biomarkers are being investigated in order to facilitate early and correct diagnosis and treatment of HRS-AKI and other forms of AKI in patients with *** review summarizes the current diagnostic criteria,as well as pathophysiologic and therapeutic concepts for AKI and HRS-AKI in cirrhosis.

关键词： liver cirrhosis acute kidney injury hepatorenal syndrome

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Missing and murdered indigenous women and girls in Canada:a new population affinity assessment technique to aid in identification using 3D technology

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Forensic Sciences Research 2022年第3期7卷 427-439页

作者： elisabeth Cuerrier-Richer Department of Anthropology University of TorontoTorontoOntarioCanada

As of 2015,204 cases of missing and murdered Indigenous women and girls(MMIWG)remained unsolved in Canada,making it a major concern for Canadian Indigenous communities,who are still pressing for the resolution of these *** forensic anthropology,the assessment of population affinity can be useful to help identify *** affinity,previously referred to as ancestry,is evaluated based on morphological analyses,which examine the size and shape of skeletal features,and metric analyses,which utilise skeletal ***,morphological analyses strongly depend on an anthropologist’s experience with human variation,which makes the analyses particularly challenging to reproduce and *** purpose of this study is to improve the rigour of morphological analyses by using 3D technology to quantify relevant cranial nonmetric population affinity *** there is currently little morphological data available for the Canadian Indigenous population,this research aims to develop a new technique that could aid in the identification of *** study comprised a total of 87 adult female crania,including 24 of Canadian Inuit origin,50 of European descent and 13 of African *** samples were imaged using photogrammetry,then analysed using a 3D shape analysis in 3DS *** show that this method is satisfactory in correctly evaluating population affinity with an accuracy of 87.36%(jackknifed:80.46%)and an average repeatability of 97%.Unfortunately,the small Canadian Indigenous sample size impacted the applicability of the results and further research will be required before the technique can be used to aid in the identification of MMIWG in Canada.

关键词： Forensic sciences forensic anthropology population affinity assessment Canadian Indigenous morphological analyses cranial traits 3D shape analysis

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From Academic Nitpicking to a =New Culture Movement＇： How Newspapers Turned Academic Debates into the Center of ~May Fourth＂

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Frontiers of History in China 2014年第4期9卷 534-557页

作者： elisabeth Forster Faculty of History University of Oxford Oxford OX 1 2RL United Kingdom

Abstract In early 1919, people like Hu Shi and Chen Duxiu were regarded as members of an ivory-tower ＂academic faction＂（xuepai）, embroiled in a debate with an opposing ＂faction.＂ After the May Fourth demonstrations, they were praised as the stars of a ＂New Culture Movement.＂ However, it was not obvious how the circle around Hu Shi and Chert Duxiu was associated with the May Fourth demonstrations. This link hinged on the way in which newspapers like Shenbao reported about the academic debates and the political events of May Fourth. After compartmentalizing the debating academics into fixed xuepai, Shenbao ascribed warlord-political allegiances to them. These made the Hu-Chen circle look like government victims and their ＂factional＂ rivals like the warlords＇ allies. When the atmosphere became hostile to the government during May Fourth, Hu Shi＇s ＂faction＂ became associated with the equally victimized May Fourth demonstrators. Their ideas were regarded as （now popular） expressions of anti-government sentiment, and soon this was labeled the core of the ＂New Culture Movement.＂ The idea and rhetoric of China＇s ＂New Culture Movement＂ in this way emerged out of the fortuitous concatenation of academic debates, newspaper stories, and political events.

关键词： May Fourth Movement New Culture Movement Shenbao academicfactions (xuepai) Chinese newspapers

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Dual liver transplantation

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2013年第3期14卷 178-184页

作者： Hao CHEN Ying ZHANG Yong-mei HAN Emmanue huguet Dong-sheng HUANG Jia-hong DONG Hepatobiliary Surgery Hospital and Institute of Chinese People's Liberation Army(PLA) General Hospital Division of Cardiology Department of MedicineCollege of MedicineUniversity of Florida Department of Microbiology Chinese PLA General Hospital Department of General Practice Sir Run Run Shaw HospitalCollege of MedicineZhejiang University Department of General Surgery National Institute for Health Research(NIHR) Comprehensive Biomedical CampusAddenbrookes Hospital Department of General Surgery Zhejiang Provincial People's Hospital

Reperfusion is the key strategy in acute ST-segment elevation myocardial infarction(STEMI) care,and it is *** the time from symptom to reperfusion and choosing the optimal reperfusion strategy for STEMI patients are great challenges in *** need to improve upon the problems of low reperfusion rate,non-standardized treatment,and economic burden in STEMI *** article briefly reviews the current status of reperfusion strategy in STEMI care,and also introduces what we will do to bridge the gap between the guidelines and implementation in the clinical setting through the upcoming China STEMI early reperfusion program.

关键词：外科学手术器官移植术医学

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