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Systematic review of absorbable vs non-absorbable sutures used for the closure of surgical incisions

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World Journal of Gastrointestinal Surgery 2014年第12期6卷 241-247页

作者： Muhammad S Sajid Malcolm R mc Fall Pauline A Whitehouse Parv S Sains Western Sussex Hospitals NHS Trust Washington Suite North Wing Worthing Hospital BN11 2DH West Sussex United Kingdom Department of General Endoscopic and Laparoscopic Colorectal Surgery Worthing Hospital Worthing BN11 2DH West Sussex United Kingdom

AIM: To report a systematic review of published randomized controlled trials(RCTs) investigating the role of absorbable suture(AS) against non-AS(NAS) used for the closure of surgical ***: RCTs investigating the use of AS vs NAS for the closure of surgical incisions were statistically analysed based upon the principles of meta-analysis and the summated outcomes were represented as ***: The systematic search of medical literature yielded 10 RCTs on 1354 patients. Prevalence of wound infection(OR = 0.97; 95%CI: 0.56, 1.69; Z = 0.11; P = 0.92) and operative morbidity(P = 0.45) was comparable in both groups. Nonetheless, the use of AS lead to lower risk of wound break-down(OR = 0.12; 95%CI: 0.04, 0.39; Z = 3.52; P < 0.0004).CONCLUSION: This meta-analysis of 10 RCTs demonstrates that the use of AS is similar to NAS for skin closure for surgical site infection and other operative morbidities. AS do not increase the risk of skin wound dehiscence,rather lead to a reduced risk of wound dehiscence compared to NAS.

关键词： Skin closure Surgical site infection Wound dehiscence Absorbable sutures Non-absorbable suture

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慢性酒精中毒病人迷走神经的病理改变

中华精神科杂志 1990年第4期23卷 234-236+255页

作者：郭玉璞 mc Leod J G 北京协和医院神经科悉尼大学内科

报道迷走神经植物性成分的研究方法并对6例慢性酒精中毒死亡病例和4例对照组(非酒精中毒死亡病例)的迷走神经进行了病理学研究。其结果为近端有髓纤维的密度和形态改变较轻,而远端则病变明显,单纤维神经证实近端为继发性节段性脱髓,远... 详细信息

报道迷走神经植物性成分的研究方法并对6例慢性酒精中毒死亡病例和4例对照组(非酒精中毒死亡病例)的迷走神经进行了病理学研究。其结果为近端有髓纤维的密度和形态改变较轻,而远端则病变明显,单纤维神经证实近端为继发性节段性脱髓,远端为轴索变性。结论:慢性酒精中毒组的迷走神经病变为逆向变性周围神经病。

关键词：酒精中毒迷走神经轴索变性

ENSO and Southeast Asian biomass burning modulate subtropical trans-Pacific ozone transport

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National Science Review 2021年第6期8卷 120-127页

作者： Lian Xue Aijun Ding Owen Cooper Xin Huang Wuke Wang Derong Zhou Zhaohua Wu Audra mc Clure-Begley Irina Petropavlovskikh Meinrat O.Andreae Congbin Fu Joint International Research Laboratory of Atmospheric and Earth System Sciences School of Atmospheric SciencesNanjing University Jiangsu Provincial Collaborative Innovation Center for Climate Change Cooperative Institute for Research in Environmental Sciences University of Colorado Chemical Sciences Division NOAA Earth System Research Laboratory Department of Earth Ocean and Atmospheric SciencesFlorida State University Global Monitoring Division NOAA Earth System Research Laboratory Max Planck Institute for Chemistry Scripps Institution of Oceanography University of California

Trans-Pacific transport of enhanced ozone plumes has been mainly attributed to fossil fuel combustion in Asia in spring, but less attention has been paid to vegetation fires in Asia. Here we show that the El Ni?noSouthern Oscillation(ENSO)-modulated fires in Southeast Asia, rather than Asian fossil fuel plumes,dominate the interannual variability of springtime trans-Pacific transport of ozone across the entire North Pacific Ocean. During El Ni?no springs, the intensified fires from both the Indochinese Peninsula and Indonesia, together with large-scale circulation anomalies, result in enhanced ozone plumes that stretch over 15 000 km in both the lower-middle and upper troposphere. This enhancement is also observed in the in situ measurements of ozone concentration, with an almost 10% increase at Mauna Loa Observatory,Hawaii, a unique site to monitor the long-distance transport over the North Pacific. This study reports an unexpectedly strong influence of vegetation fires, linked with climate variability, on global tropospheric chemistry and proves once more how complex the interactions in the climate system are.

关键词： El Niño-Southern Oscillation (ENSO) climate biomass burning tropospheric ozone long-range transport Southeast Asia

Burden of nonalcoholic fatty liver disease and advanced fibrosis in a Texas Hispanic community cohort

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World Journal of Hepatology 2015年第11期7卷 1586-1594页

作者： Jen-Jung Pan Susan P Fisher-Hoch Chaoru Chen Ariel E Feldstein Joseph B mc Cormick Mohammad H Rahbar Laura Beretta Michael B Fallon Division of Gastroenterology Hepatology and Nutrition Department of Internal Medicine the University of Texas Health Science Center at Houston School of Public Health Brownsville Campus the University of Texas Health Science Center at Houston Division of Gastroenterology Hepatology and Nutrition Department of Pediatrics University of California at San Diego Division of Clinical and Translational Sciences Department of Internal Medicine the University of Texas Health Science Center at Houston Division of Epidemiology Human Genetics and Environmental Sciences School of Public Health the University of Texas Health Science Center at Houston Department of Molecular and Cellular Oncology the University of Texas MD Anderson Cancer Center

AIM: To investigate the potential burden of nonalcoholic steatohepatitis(NASH) and advanced fibrosis in a hispanic ***: Four hundred and forty two participants with available ultrasonography data from the Cameron County Hispanic Cohort were included in this study. Each participant completed a comprehensive questionnaire regarding basic demographic information, medical history, medication use, and social and family history including alcohol use. Values of the nonalcoholic fatty liver disease fibrosis score(NFS), FIB4 index, BARD score, and Aspartate aminotransferase to Platelet Ratio Index(APRI) were computed using the blood samples collected within 6 mo of liver ultrasonography from each participant. Hepatic steatosis was determined by ultrasonography. As part of univariable analysis, for continuous variables, comparisons among groups were performed with student-t test, one way analysis of variance, and Mann-Whitney test. Pearson χ2 and the Fisher exact test are used to assess differences in categorical variables. For multivariable analyses, logistic regression analyses were performed to identify characteristics associated with hepatic steatosis. All reported P values are based two-sided tests, and a P value of less than 0.05 was considered to indicate statistical ***: The mean age and body mass index(BMI) of the study participants were 49.1 years and 31.3 kg/m2, respectively. Among them, 65.6% were females, 52% had hepatic steatosis, 49.5% had metabolic syndrome, and 29% had elevated aminotransferases. Based on established cut-offs for diagnostic panels, between 17%-63% of the entire cohort was predicted to have NASH with indeterminate or advanced fibrosis. Participants with hepatic steatosis had significantly higher BMI(32.9 ± 5.6 kg/m2 vs 29.6 ± 6.1 kg/m2, P < 0.001) and higher prevalence rates of elevation of ALT(42.2% vs 14.6%, P < 0.001), elevation of aspartate aminotransferase(38.7% vs 18.9%, P < 0.001), and metabolic syndrome(6

关键词： Noninvasive biomarkers Nonalcoholic fattyliver disease Hispanics Ultrasonography Liver fibrosis

Effects of Biological Materials and Collection Media on PCR Detection of <i>Tritrichomonas foetus</i>

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Open Journal of Animal Sciences 2019年第1期9卷 121-128页

作者： Kristin A. Clothier Bret mc Nabb Andrea Torain Steve Reinl Jeff Ondrak California Animal Health and Food Safety Laboratory System Davis CA USA Department of Population Health and Reproduction School of Veterinary Medicine University of California Davis Davis CA USA Great Plains Veterinary Educational Center University of Nebraska-Lincoln Clay Center NE USA

Tritrichomonas foetus is an important pathogen of the bovine reproductive tract causing early embryonic death and abortion in cows and persistent, asymptomatic infection in bulls. PCR detection methods have greatly enhanced diagnostic accuracy over culture;however, pre-analytical sample handling is just as critical as technical performance in detecting this pathogen and is not well studied. The purpose of this study was to investigate the effects of biological materials present in the prepuce on PCR detection of T. foetus in a variety of collection media. Simulated preputial samples were created using InPouchTM (IP) media, lactated ringers solution (LRS), or sterile saline (SAL);inoculated with low numbers of one of three T. foetus strains;and spiked with either blood, semen, urine, or sham treatment. Samples were transported to the lab, placed in growth media (LRS and SAL samples), incubated, and tested for T. foetus by PCR. Samples containing urine had statistically significantly greater mean Ct values (P = 0.008) than samples containing other materials, seen most dramatically in IP (P < 0.0001.) Urine contamination resulted in significantly (P = 0.037) fewer samples being identified as “positive” for T. foetus. Overall, SAL collections also had significantly higher mean Ct than IP or LRS (P < 0.001), and were less likely (P = 0.018) to results in classification as a “positive” sample. Results of this study indicate that collection media and biological materials can affect T. foetus PCR detection. The presence of urine in preputial samples can result in false negative results, while blood had no detrimental effects.

关键词： Tritrichomonas foetus PCR Detection Urine Semen Blood

Virtual reality for Parkinson disease

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中华物理医学与康复杂志 2019年第5期41卷 358-358页

作者： Maggio MG De Cola mc Latella D 不详

BACKGROUND AND OBJECTIVE The prevalence of Parkinson's disease ( PD) in industrialized countries is 0.3% in the general population. This study evaluated the effects of virtual reality training ( VRT) on motor and cogn... 详细信息

关键词： Parkinson's disease(PD) virtual reality training(VRT) recovery

日本血吸虫尾蚴抗原免疫血清筛选成虫cDNA文库与新基因分析

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中国寄生虫学与寄生虫病杂志 2003年第5期21卷 289-292页

作者：袁仕善易新元曾宪芳欧阳理王敏唐连飞 Larry mc Reynolds 中南大学湘雅医学院血吸虫病研究室 Molecular Parasitology Group New England BiolabsMA01915USA

目的　筛选与日本血吸虫尾蚴抗原有共同免疫原性的日本血吸虫成虫抗原分子 ,为血吸虫病诊断和疫苗研究提供新的候选分子。　方法　利用日本血吸虫尾蚴可溶性抗原免疫兔血清筛选日本血吸虫 (Schistosomajapon icum ,Sj)成虫cDNA文库 ,对... 详细信息

目的　筛选与日本血吸虫尾蚴抗原有共同免疫原性的日本血吸虫成虫抗原分子 ,为血吸虫病诊断和疫苗研究提供新的候选分子。　方法　利用日本血吸虫尾蚴可溶性抗原免疫兔血清筛选日本血吸虫 (Schistosomajapon icum ,Sj)成虫cDNA文库 ,对阳性克隆的插入片段进行PCR扩增和序列分析。　结果　共筛选出 13个阳性克隆 ,PCR扩增出特异的插入片段。测序分析获 4个新基因SjCAI、SjCA、SjCAI 2和SjCAI 3 (登录号分别为AF495 883、AF5 15 83 4、AY1180 86和AY12 93 0 3 ) ,分别编码 3 5 3、161、13 7和 72个氨基酸的蛋白。SjCAI蛋白含 6个DNA结合锌指 ,与原肠胚锌指蛋白XLCGF48.2有一定同源性 ;SjCA蛋白、SjCAI 2蛋白和SjCAI 3蛋白含N 糖基化和磷酸化位点。　结论　筛选Sj成虫cDNA文库获得了新的基因序列。

关键词：日本血吸虫尾蚴抗原免疫血清筛选成虫 cDNA文库新基因分析

GeForce 6600GT的终结者 7300GT超值显卡大搜罗

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现代计算机（中旬刊） 2006年第7期 80-82页

作者： PCPOP & mc

核心代号为 NV45的 GeForce 6600系列产品堪称 nVIDIA 经典之作,作为 nVIDIA 第一款原生 PCI-E 显示芯片,首款110nm 制程产品。NV43凭借其出众的性能、领先的技术优势几乎横扫整个当年的中高端显卡市场……然而,这一切似乎将随着GeForce... 详细信息

核心代号为 NV45的 GeForce 6600系列产品堪称 nVIDIA 经典之作,作为 nVIDIA 第一款原生 PCI-E 显示芯片,首款110nm 制程产品。NV43凭借其出众的性能、领先的技术优势几乎横扫整个当年的中高端显卡市场……然而,这一切似乎将随着GeForce 7300GT 的发布而改变。

关键词： GeForce 显卡市场 nVIDIA 终结系列产品核心代号显示芯片 PCI 高端

利用微卫星标记扩充水稻双单倍体群体的遗传图谱

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科学通报 1997年第20期42卷 2220-2223页

作者：沈利爽朱立煌 SR.mc Cuch 徐云碧中国科学院遗传研究所 Cornell 大学植物育种和生物统计系美国N.Y.14853

微卫星标记已在人类与动物的遗传作图中得到了广泛应用.微卫星标记所揭示的是简单顺序长度多态性(Simple Sequence Length Polymorphism,SSLP),可利用PCR方法检测,因而快速简便,而且所需DNA量少.微卫星标记在遗传分析中表现为共显性,具... 详细信息

微卫星标记已在人类与动物的遗传作图中得到了广泛应用.微卫星标记所揭示的是简单顺序长度多态性(Simple Sequence Length Polymorphism,SSLP),可利用PCR方法检测,因而快速简便,而且所需DNA量少.微卫星标记在遗传分析中表现为共显性,具有高度的多态性,往往有多个等位形式存在,信息含量很高,目前,在植物中微卫星标记主要用于基因型分析,品系分析及基因定位,尚未大规模用于遗传作图,在水稻中,通过筛选基因组文库和检索DNA序列库,已经获得了58个微卫星标记.本研究对一个水稻双单倍体(DH)群体进行了微卫星标记遗传作图工作,将89个微卫星标记较均匀地定位在已有的遗传图谱上。

关键词：微卫星标记水稻双单倍体群体遗传图谱