检索结果-南通市图书馆

Adalimumab in prevention of postoperative recurrence of Crohn's disease in high-risk patients

World Journal of Gastroenterology 2012年第32期18卷 4391-4398页

作者： Mariam Aguas Guillermo Bastida elena cerrillo Belén Beltrán Marisa Iborra Cristina Sánchez-Montes Fernando Muoz Jesús Barrio Sabino Riestra Pilar Nos Gastroenterology Unit Department of Digestive DiseaseNetworked Biomedical Research Center for Hepatic and Digestive DiseasesLa Fe University and Politechnic Hospital46026 ValenciaSpain Department of Gastroenterology La Fe University and Politechnic Hospital46026 ValenciaSpain Leon Hospital Complex 42132 LeónSpain Río Hortega University Hospital 47001 ValladolidSpain Central University Hospital of Asturias 33006 OviedoSpain

AIM:To evaluate the effectiveness of adalimumab in preventing recurrence after intestinal resection for Crohn's disease in high-risk ***:A multicenter,prospective,observational study was conducted from June 2009 until June *** consecutively included high-risk Crohn's disease patients who had undergone an ileal/ileocolonic ***-risk patients were defined as two or more criteria:smokers,penetrating pattern,one or more previous surgical resections or prior extensive *** adalimumab was administered 2 wk(± 5 d) after surgery at a dose of 40 mg eow,with an initial induction dose of 160/80 mg at weeks 0 and *** data,previous and concomitant treatments(antibiotics,5-aminosalicylates,corticosteroids,immunomodulators or biologic therapies),smoking status at the time of diagnosis and after the index operation and number of previous resections(type and reason for surgery) were all *** status was assessed with C-reactive protein,erythrocyte sedimentation rate and fecal *** year(± 3 mo) after surgery,an ileocolonoscopy and/or magnetic resonance enterography was *** recurrence was defined as Rutgeerts score ≥ *** recurrence was based on magnetic resonance(MR) score ≥ ***:Twenty-nine patients(55.2% males,48.3% smokers at diagnosis and 13.8% after the index operation),mean age 42.3 years and mean duration of the disease 13.8 years were included in the study.A mean of 1.76(range:1-4) resections previous to adalimumab administration and in 37.9% was considered extensive resection.51.7% had previously received *** were given concomitantly to 17.2% of *** of the 29(13.7%) developed clinical recurrence,6/29(20.7%) endoscopic recurrence and 7/19(36.8%) morphological recurrence after *** patients with clinical recurrence showed endoscopic and morphological recurrence.A high degree of concordance was found between clinical-endosc

关键词： Crohn's disease Postoperative recurrence Prevention Tumor necrosis factor alpha agents Adalimumab

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Experimental Investigation of Demand Controlled Ventilation Systems： A Suitable Alternative for Controlling Ventilation in Dwellings

引用

Journal of Energy and Power Engineering 2012年第10期6卷 1553-1559页

作者： Victor Jose del Campo Diaz Jon Teres-Zubiaga elena Ruiz cerrillo Department of Thermal Engineering University of the Basque Country Bilbao 48013 Spain Euskadi Public Housing and Soil Joint-Stock Company Vitoria-Gasteiz 01013 Spain

Indoor CO2 concentration depends on the number of persons, their metabolic rates, other sources of indoor pollution, ventilation rate and ventilation efficiency. These factors are not considered by the Spanish technical building code since ventilation is set only by a fixed air change rate. This paper aims to explore the possibilities of DCVS （demand controlled ventilation systems） to ensure adequate and sustainable ventilation. It is based on a research project carried out by the University of the Basque Country （EHU-UPV） and Euskadi Public Housing and Soil Join-Stock Company （VISESA）： the living rooms of 90 dwellings were provided with DCVS, where CO2 sensors were used to dynamically control the ventilation rate. Tests were carried out using tracer gas techniques, with results showing the air age to be adequate at every point of the occupied zones and free of stagnant areas, therefore proving the system＇s effectiveness and rapid response, and its energy savings.

关键词： DCVS (demand controlled ventilation systems) energy efficiency indoor air quality.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Benzyl Amino Purine and Gibberellic Acid Coupled to Nitrogen-Limited Stress Induce Fatty Acids,Biomass Accumulation,and Gene Expression in Scenedesmus Obliquus

引用

Phyton-International Journal of Experimental Botany 2021年第2期90卷 515-531页

作者： Hans Christian Correa-Aguado Gloria Viviana cerrillo-Rojas Alejandro Rocha-Uribe Ruth elena Soria-Guerra JoséFrancisco Morales-Domínguez Departamento de Química Centro de Ciencias BásicasUniversidad Autónoma de AguascalientesAguascalientes20131México Facultad de Ciencias Químicas Universidad Autónoma de San Luis PotosíSan Luis Potosí78210México Instituto Politécnico Nacional Unidad Profesional Interdisciplinaria de Ingeniería Campus ZacatecasBlvd.del Bote 202Cerro del Gato Ejido La EscondidaCol.Ciudad AdministrativaZacatecasZAC 98160Mexico

The need for renewable energy sources makes microalgae an essential feedstock for biofuels *** molecular aspects and the response to nitrogen(N)-limited conditions with a phytohormone stimulus in microalgae have been slightly *** this work,Scenedesmus obliquus was used as a study model to analyze the effect of benzyl amino purine(BAP)and gibberellic acid(GA)coupled to nitrogen limitation on cell growth,biomass and fatty *** selected 10^(-5)M BAP increased the biomass by 1.44-fold,and 10^(-6)M GA by *** total lipids also increased by 2.8 and 1.11-fold,*** 10^(-5)M BAP and 10^(-6)M GA addition to *** cultures at different initial nitrogen percentages(N-0,N-25,and N-50)showed a significant increase in cell growth and biomass productivity compared to the unstimulated *** N-0 and GA N-0 produced the highest lipid yields with 55%and 50%,*** lipid profile analysis revealed an increase,particularly in C18:1 and C16:0 fatty *** expression analysis showed an over-expression of acyl carrying protein(ACP),stearoyl-ACP desaturase(SAD),fatty acid acyl-ACP thioesterase(FATA),and diacylglycerol acyltransferase(DGAT)genes,which were mainly induced by nitrogen ***,BAP and GA produced a significant over-expression on these genes in the N-replete *** study shows that BAP and GA,coupled to N limitation stress,can be used to increase the biomass and lipid production in *** for sustainable biofuels.

关键词： Biodiesel gene expression lipids microalgae nitrogen deficiency phytohormones

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

In Vitro Propagation, Isolation and Expression Studies of Suaeda edulis Genes Involved in the Osmoprotectants Biosynthesis

引用

Phyton-International Journal of Experimental Botany 2020年第3期89卷 715-726页

作者： Gloria Viviana cerrillo-Rojas Mariana Tiscareno-Andrade Ana Erika Ochoa-Alfaro Eugenio Perez-Molphe Balch Ruth elena Soria-Guerra Jose Francisco Morales-Dominguez Departamento de Quimica Universidad Autonoma de AguascalientesCentro de Ciencias BasicasCiudad UniversitariaAguascalientes20131Mexico Facultad de Quimica Universidad Autonoma de San Luis PotosiZona UniversitariaSan Luis Potosi78210Mexico

Halophytes are an excellent choice for the study of genes conferring salt tolerance to salt-sensitive plants and,they are suitable for reclamation and remediation of saline *** develop an in vitro plant propagation protocol and studies of genes involved with GB and Pro biosynthesis in Suaeda *** buds were used as explants and cultured in different treatments on Murashige and Skoog(MS)medium supplemented with different concentrations and combinations of plant growth *** highest number of multiple shoots was on MS medium containing 1 mg/L Benzyladenine(BA)and/or 2 g/L activated carbon with 5.5±06 shoots per *** identification and expression analysis of genes involved in glycine betaine(GB)biosynthesis were S-adenosyl-methionine synthetase(SAMS),choline monooxygenase(CMO)and betaine alde-hyde dehydrogenase(BADH),and for proline(Pro)was pyrroline 5-carboxylate synthetase(P5CS).These sequences shared 90–95%of identity with others plant homologous in public *** amino acids sequence analysis showed that all these peptides contain some of the conserved motifs of those kinds of *** qRT-PCR analysis revealed a higher expression of SeBADH,SeCMO,and,SeP5CS genes in the roots and leaves from plants collected in the field in contrast with from in vitro ***,the expression level of SeSAMS was higher only in the leaves of plants collected in the field when com-pared to those cultivated in vitro.

关键词： Axillary buds halophyte proline glycine betaine salt-resistant

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：