检索结果-南通市图书馆

Cellular arsenic transport pathways in mammals

Journal of Environmental Sciences 2016年第11期28卷 38-58页

作者： Barbara A.Roggenbeck mayukh Banerjee elaine m.leslie Department of Physiology and membrane Protein Disease Research Group University of Alberta Division of Analytical and Environmental Toxicology Department of Laboratory Medicine and Pathology University of Alberta

Natural contamination of drinking water with arsenic results in the exposure of millions of people world-wide to unacceptable levels of this metalloid. This is a serious global health problem because arsenic is a Group 1（proven） human carcinogen and chronic exposure is known to cause skin, lung, and bladder tumors. Furthermore, arsenic exposure can result in a myriad of other adverse health effects including diseases of the cardiovascular,respiratory, neurological, reproductive, and endocrine systems. In addition to chronic environmental exposure to arsenic, arsenic trioxide is approved for the clinical treatment of acute promyelocytic leukemia, and is in clinical trials for other hematological malignancies as well as solid tumors. Considerable inter-individual variability in susceptibility to arsenic-induced disease and toxicity exists, and the reasons for such differences are incompletely understood. Transport pathways that influence the cellular uptake and export of arsenic contribute to regulating its cellular, tissue, and ultimately body levels. In the current review, membrane proteins（including phosphate transporters, aquaglyceroporin channels, solute carrier proteins, and ATP-binding cassette transporters） shown experimentally to contribute to the passage of inorganic, methylated, and/or glutathionylated arsenic species across cellular membranes are discussed. Furthermore, what is known about arsenic transporters in organs involved in absorption, distribution, and metabolism and how transport pathways contribute to arsenic elimination are described.

关键词： Arsenic Glutathione Cellular uptake Cellular efflux Transport

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An electropenetrography waveform library for the probing and ingestion behaviors of Culex tarsalis on human hands

引用

Insect Science 2024年第4期31卷 1165-1186页

作者： Anastasia m.W.Cooper Samuel B.Jameson Victoria Pickens Cameron Osborne elaine A.Backus Kristopher Silver Dana N.mitzel Department of Entomology Kansas State UniversityManhattanKansasUSA Department of Tropical medicine Tulane University School of Public Health and Tropical MedicineNew OrleansLos AngelesUSA USDA Agricultural Research Service San Joaquin Valley Agricultural Sciences CenterParlierCaliforniaUSA National Bio and Agro-Defense Facility USDA Agricultural Research ServiceManhattanKansasUSA

Culex tarsalis Coquillett(Diptera:Culicidae)mosquitoes are capable of vectoring numerous pathogens affecting public and animal ***,the probing behaviors of mosquitoes are poorly understood because they occur in opaque ***(EPG)has the potential to elucidate these behaviors by recording the electrical signals generated during *** used an AC–DC EPG with variable input resistors(Ri levels)to construct a waveform library for *** feeding on human *** events associated with mosquito probing were used to characterize waveforms at four Ri levels and with two electrical current *** optimal settings for EPG recordings of *** probing on human hands was an Ri level of 10^(7)Ohms using an applied signal of 150 millivolts alternating *** for *** included those previously observed and associated with probing behaviors in Aedes aegypti L.(Diptera:Culicidae):waveform families J(surface salivation),K(stylet penetration through the skin),L(types 1 and 2,search for a blood vessel/ingestion site),m(types 1 and 2,ingestion),N(type 1,an unknown behavior which may be a resting and digestion phase),and W(withdrawal).However,we also observed variations in the waveforms not described in ***,which we named types L3,m3,m4,and *** investigation enhances our understanding of mosquito probing *** also provides a new tool for the automated calculation of peak *** work will facilitate future pathogen acquisition and transmission studies and help identify new pest and disease management targets.

关键词： AC-DC blood feeders electrical penetration graph EPG human hands mosquitoes waveform library

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Refractory Ventricular Fibrillation with Underlying Coronary Artery Disease after COVID-19 Vaccine-Kounis Syndrome or Coincidence

引用

Case Reports in Clinical medicine 2024年第8期13卷 309-314页

作者： elaine m. C. Chau Cardiology Centre Hong Kong Sanatorium & Hospital Hong Kong SAR China

A 63-year-old man with diabetes and asymptomatic coronary artery disease developed refractory ventricular arrhythmia at 20 hours at rest after his second COVID-19 vaccine. Despite significant stenosis in the coronary arteries, there was no evidence of acute or old myocardial infarction, heart failure, myocarditis or structural abnormalities on post-mortem to account for the substrate for the fatal arrhythmia. The refractory and incessant nature of the ventricular fibrillation and post-mortem finding of a grossly elevated unexplained IgE level (in the absence of acute myocardial infarction) suggested the possibility of Kounis Syndrome or allergic acute coronary syndrome.

关键词： Refractory Ventricular Fibrillation COVID-19 Vaccine Kounis Syndrome

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

人工智能能耗惊人

引用

Engineering 2024年第1期32卷 7-9页

作者： mitch leslie Senior Technology Writer

In the month of August 2023,more than 180 million users logged on to ChatGPT(Fig.1)[1],the famous artificial intelligence(AI)chatbot[2].Developed by San Francisco,CA,USA-based OpenAI,ChatGPT can write prose in the style of Ernest Hemingway,generate computer code,help jobseekers craft their resumes,furnish reasonably accurate medical diagnoses,and perform a range of other sophisticated tasks[2-5].People who sign up for the free version of ChatGPT-as well as anyone else accessing the many Al-enhanced search engines and programs that are now available-do not have to pay for the *** it is not actually free.

关键词：人工智能 computer artificial

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Add-on Renewables Aim to Decrease Impact and Increase Benefits

引用

Engineering 2024年第6期37卷 10-12页

作者： mitch leslie Senior Technology Writer

In the South Boulder Canal near Denver,CO,USA,turbine blades that resemble the mixers used to stir cake batter in kitchens(Fig.1)spin in the rushing water[1].Each of the turbines,manufactured by Emrgy of Atlanta,GA,USA,generates up to 25 kW of electricity for the area’s grid[2].In an orchard in southern Italy,an arcade of solar panels stands above rows of citron trees,which are valuable for the essential oils in their fruits[3].The solar panels not only produce electricity for local homes,but also protect the trees from the sun,reducing their water use by 70%[3].These are two examples of a clean energy trend:integrating power-generation with other *** the approach called agrivoltaics,for example,farmers and ranchers grow crops or raise livestock around and beneath solar panels(Fig.2)[4].Experts hope that such add-on strategies can spare farmland,cut the environmental costs of clean energy development,supply extra income to landowners,and furnish other benefits[5,6].

关键词： income beneath integrating

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

日本福岛核污染水排海引发争议

引用

Engineering 2024年第3期34卷 6-8页

作者： mitch leslie Senior Technology Writer

In late August 2023,China cut off seafood imports from Japan[1]and criticized its neighbor for being “extremely selfish and irresponsible”[2].In Seoul,the Republic of Korea,protesters marched through the streets,held a candlelight vigil,and attempted to force their way into the Japanese embassy[3].The environmental organization Greenpeace denounced Japan for violating human rights and breaking international law[4].

关键词：核污染 breaking peace

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

人工智能或将引发科学革命

引用

Engineering 2024年第4期35卷 4-6页

作者： mitch leslie Senior Technology Writer

A drug developer trying to devise a new cancer treatment,a virologist investigating how a virus invades cells,an evolutionary biologist probing the effects of mutations on an organism’s fitness—these are just some of the scientists who need to know the three-dimensional structures of specific ***,deducing a protein’s shape through experiments is laborious and costly[1].

关键词：人工智能 cancer treatment

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Promising Results Predict Role for Artificial Intelligence in Weather Forecasting

引用

Engineering 2024年第8期39卷 10-12页

作者： mitch leslie Senior Technology Writer

Artificial intelligence(AI)has already demonstrated its proficiency at difficult scientific tasks like predicting how proteins will fold and identifying new astronomical objects in masses of observational data[1].Now,recent results suggest that AI also excels at weather *** global predictions,GraphCast,an AI system developed by Google subsidiary Deepmind(London,UK),outperforms the state-of-the-art model from the European Centre for medium-Range Weather Forecasts(ECmWF),providing more accurate projections of variables such as temperature and humidity 90%of the time[2,3].Other AI systems,including Pangu-Weather from the Chinese tech company Huawei(Shenzhen,China)[4],can also match or beat traditional global forecasting models.

关键词： forecasting humidity weather

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Is There a Bright Future for Solar Power from Space?

引用

Engineering 2024年第2期33卷 9-11页

作者： mitch leslie Senior Technology Writer

Late in the evening of may 22,2023,a team of researchers at the California Institute of Technology(Caltech)in Pasadena,CA,USA,measured a faint beam of microwaves emanating from a solar-powered satellite 550 km *** send signals to Earth all the time,but this occasion was *** satellite car-ried a unique transmitter developed by the Caltech researchers,a 30 cm by 30 cm array of polyimide and copper designed to be lightweight and *** that transmitter,the satellite became the first spacecraft to direct solar power captured in space to the Earth’s surface.

关键词： Earth Solar lightweight

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Can Giant microchips Become a Big Deal?

引用

Engineering 2024年第5期36卷 6-8页

作者： mitch leslie Senior Technology Writer

For decades,manufacturers have boasted about how small they can make microchip *** have shrunk by about 1000-fold over the last 50 years,for example[1].But Cerebras Systems,*** Sunnyvale,CA,USA takes pride in how big its chips *** from a single silicon wafer,its Wafer-Scale Engine(WSE)-2 chips measure 46225 mm^(2),56 times the size of a standard Nvidia microprocessor(Fig.1)[2].

关键词： microprocessor microchip Engine

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：