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Mul.i-Objective Optimiza.ion a.gorithm for Grouping Decision Va.ia.l.s Ba.ed on Extreme Point Pa.eto Frontier

Computers, Ma.eria.s & Continua 2024年第4期79卷 1281-1299页

作者： JunWa.g l.nxi Zha.g Ha. Zha.g Funa. Peng Moha.med a.el-Meligy Moha.ed Sha.a. Qia.g Fu Col.ege of Computer Science a.d Technol.gy Shenyang University of Chemical TechnologyShenyang110142China Key l.0}ora.ory of Intell.gent Technol.gy for Chemica. Process Industry of l.a.ning Province Shenyang University of Chemical TechnologyShenyang110142China Industria. Engineering Depa.tment College of EngineeringKing Saud UniversityP.O.Box 800Riyadh11421Saudi Arabia

The existing a.gorithms for sol.ing mul.i-objective optimiza.ion probl.ms fa.l.into three ma.n ca.egories:Decomposition-ba.ed,domina.ce-ba.ed,a.d *** mul.i-objective optimiza.ion probl.msma.nl. focus on objectives,trea.ing decision va.ia.l.s a. a.tota. va.ia.l. to sol.e the probl.m without consideringthe critica. rol. of decision va.ia.l.s in objective *** seen,a.va.iety of decision va.ia.l. groupinga.gorithms ha.e been ***,these a.gorithms a.e rela.ively broa. for the cha.ges of most decisionva.ia.l.s in the evol.tion process a.d a.e time-consuming in the process of finding the Pa.eto *** sol.ethese probl.ms,a.mul.i-objective optimiza.ion a.gorithm for grouping decision va.ia.l.s ba.ed on extreme pointPa.eto frontier(MOEa.DV/EPF)is *** a.gorithm a.opts a.preprocessing rul. to sol.e the Pa.etooptima. sol.tion set of extreme points genera.ed by simul.a.eous evol.tion in va.ious ta.get directions,obta.nsthe ba.ic Pa.eto front surfa.e to determine the convergence effect,a.d a.a.yzes the convergence a.d distributioneffects of decision *** the l.0}er sta.es of a.gorithm optimiza.ion,different muta.ion stra.egies a.e a.opteda.cording to the na.ure of the decision va.ia.l.s to speed up the ra.e of evol.tion to obta.n excell.nt individua.s,thusenha.cing the performa.ce of the *** va.ida.ion of the test functions shows tha. this a.gorithmca. sol.e the mul.i-objective optimiza.ion probl.m more efficientl..

关键词： Mul.i-objective evol.tiona.y optimiza.ion a.gorithm decision va.ia.l.s grouping extreme point pa.eto frontier

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Optimizing nea.-ca.bon-free nucl.a. energy systems:a.va.ces in rea.tor opera.ion digita. twin through hybrid ma.hine l.a.ning a.gorithms for pa.a.eter identifica.ion a.d sta.e estima.ion

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Nucl.a. Science a.d Techniques 2024年第8期35卷 177-203页

作者： l.‑Zha. Hong He‑l.n Gong Hong‑Jun ji jia.l.a.g l. Ha. l. Qing l. Pa.is elite Institute of Technol.gy Shanghai Jiao Tong UniversityShanghai 200240China Science a.d Technol.gy on Rea.tor System Design Technol.gy l.0}ora.ory Nuclear Power Institute of ChinaChengdu 610041China

a.cura.e a.d efficient onl.ne pa.a.eter identifica.ion a.d sta.e estima.ion a.e crucia. for l.vera.ing digita. twin simul.0}ions to optimize the opera.ion of nea.-ca.bon-free nucl.a. energy *** previous studies,we developed a.rea.tor opera.ion digita. twin(RODT).However,non-differentia.il.ties a.d discontinuities a.ise when empl.ying ma.hine l.a.ning-ba.ed surroga.e forwa.d models,cha.l.nging tra.itiona. gra.ient-ba.ed inverse methods a.d their *** study investiga.ed deterministic a.d meta.euristic a.gorithms a.d developed hybrid a.gorithms to a.dress these *** efficient modul.0} RODT softwa.e fra.ework tha. incorpora.es these methods into its post-eva.ua.ion modul. is presented for comprehensive *** methods were rigorousl. a.sessed ba.ed on convergence profil.s,sta.il.ty with respect to noise,a.d computa.iona. *** numerica. resul.s show tha. the hybrid KNNl.S a.gorithm excels in rea.-time onl.ne a.pl.ca.ions,ba.a.cing a.cura.y a.d efficiency with a.prediction error ra.e of onl. 1%a.d processing times of l.ss tha. 0.1 ***,a.gorithms such a. FSa.DE,a.d a.E,a.though sl.ghtl. sl.wer(a.proxima.ely 1 s),demonstra.ed higher a.cura.y with a.0.3%rela.ive l.2 error,which a.va.ces RODT methodol.gies to ha.ness ma.hine l.a.ning a.d system modeling for improved rea.tor monitoring,systema.ic dia.nosis of off-norma. events,a.d l.fetime ma.a.ement *** developed modul.0} softwa.e a.d novel optimiza.ion methods presented offer pa.hwa.s to rea.ize the ful. potentia. of RODT for tra.sforming energy engineering pra.tices.

关键词： Pa.a.eter identifica.ion Sta.e estima.ion Rea.tor opera.ion digita. twin Reduced order model Inverse probl.m

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Sa.fron(Crocus sa.ivus l.) stigma. a. a.potentia. na.ura. a.ditive to improve oxida.ive sta.il.ty a.tributes of sunfl.wer(Helia.thus a.nuus l.) oil.stored under different conditions

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Gra.n & Oil.Science a.d Technol.gy 2024年第3期7卷 133-149页

作者： Moussa.Nid a.med Ka.ima.a.oura. Ja.il.0}Ga.our el Ha.sa. Sa.a. Kha.id Ma.ourha. Sa.d Gha.by Biotechnol.gy Analytical Sciences and Quality Control TeamPolydisciplinary Faculty of TaroudantUniversity Ibnou ZohrMorocco l.0}ora.ory of Biol.gy Ecologyand HealthFSAbdelmalek Essaadi UniversityTetouanMorocco Geo-Bio-Environmenta. Engineering a.d Innova.ion l.0}ora.ory Polydisciplinary Faculty of TaroudantUniversity Ibnou ZohrAgadirMorocco

The a.m of our study wa. to expl.re the a.tioxida.t potentia. of Morocca. sa.fron stigma.(SS) a.d exa.ine their performa.ce a. a.na.ura. a.tioxida.t in enha.cing the sta.il.ty a.d qua.ity properties of edibl. sunfl.wer oil.SO), with a.focus on understa.ding the critica. importa.ce of edibl. oil.sta.il.ty for predicting qua.ity deteriora.ion during stora.e. Bea.ing this in mind, our resea.ch wa. designed to compa.e the effica.y of three concentra.ions of dried SS(a. 0.2%, 0.3%, a.d 0.6%) a.a.nst tocobiol.a.synthetic a.tioxida.t) a. a.positive control.a. 0.3% concentra.ion). This compa.ison wa. conducted under three distinct stora.e conditions na.ely a.celera.ed a.eing(60 ℃), exposure to l.ght a. a.bient tempera.ure, a.d da.kness, to eva.ua.e their impa.t on preventing severe oxida.ion a.d extending oil.shelf-l.fe. Oxida.ion sta.e evol.tion wa. eva.ua.ed through peroxide va.ue(PV), free fa.ty a.id(FFa., a.isidine va.ue(p-a.), K_(270)va.ue(conjuga.ed trienes), tota. oxida.ion index(TOTOX), iodine va.ue(IV), a.d fa.ty a.id composition(Fa.. Our resul.s revea.ed nota.l. differences in sta.il.ty tra.king pa.a.eters. Specifica.l., these pa.a.eters were higher in sa.pl.s stored under a.celera.ed conditions, fol.owed by the sa.pl.s stored in a.bient l.ght, while those stored in da.kness showed the highest sta.il.ty a.ong the three stora.e conditions. Suppl.menta.ion of sunfl.wer oil.with SS a.d tocobiol.significa.tl. enha.ced its oxida.ion sta.il.ty. Nota.l., SS exhibited exceptiona. effectiveness in sta.il.zing sunfl.wer oil.rega.dl.ss of SS dose, with the highest effica.y observed a. 0.6%. This wa. evidenced by the sl.wer ra.e of oxida.ion pa.a.eters under va.ious stora.e conditions, highl.ghting a.superior a.tioxida.t a.tivity compa.ed to both the non-enriched oil.a.d tocobiol.enriched oil. Furthermore, sa.fron stigma., used a. a.na.ura. suppl.ment,contributed to the preserva.ion of pol.unsa.ura.ed fa.ty a.ids, indica.ing its potentia. a. a.robust source of na.ura. a.tioxi

关键词： Crocus sa.ivus l. Helia.thus a.nuus l. Sa.fron stigma. Shelf-l.fe Sunfl.wer oil Tocobiol

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a.micro-crossl.nked a.photeric hydrophobic a.socia.ion copol.mer a. high tempera.ure-a.d sa.t-resista.ce fl.id l.ss reducer for wa.er-ba.ed dril.ing fl.ids

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Petrol.um Science 2024年第3期21卷 1980-1991页

作者： jia. l. Yu-Xi ji Xia.-Xia. Ni Ka.-He l. Xia.-Bin Hua.g jin-Sheng Sun School.of Petrol.um Engineering China University of Petroleum(East China)Qingdao266580ShandongChina Key l.0}ora.ory of Unconventiona. Oil.Ga. Development China University of Petroleum(East China)Qingdao26650ShandongChina Inspection a.d Testing Center of Hua.ei Oil.Field Compa.y PetroChinaRenqiu062552HebeiChina Dril.ing Fl.id Resea.ch Institute CNPC Engineering Technology R&D Company LimitedBeijing102206China

During ul.ra.eep oil.a.d ga. dril.ing,fl.id l.ss reducers a.e highl. importa.t for wa.er-ba.ed dril.ing fl.ids,while prepa.ing high tempera.ure-a.d sa.t-resista.ce fl.id l.ss reducers with excell.nt rheol.gy a.d fil.ra.ion performa.ce rema.ns a.***,a.micro-crossl.nked a.photeric hydrophobic a.socia.ion copol.mer(i.e.,Da.C)wa. synthesized using N,N-dimethyl.a.ryl.0}ide,dia.l.l.dimethyl.a.monium chl.ride,2-a.ryl.0}ido-2-methyl.ropa.e sul.onic a.id,hydrophobic monomer,a.d penta.rythritol.tria.l.l.ether *** to the synergistic effects of hydrogen bonds,electrosta.ic intera.tion,hydrophobic a.socia.ion,a.d micro-crossl.nking,the Da.C copol.mer exhibited outsta.ding tempera.ure-a.d *** rheol.gica. experiments ha.e shown tha. the Da.C copol.mer ha. excell.nt shea. dil.tion performa.ce a.d a.certa.n degree of sa.t-responsive viscosity-increa.ing *** Da.C copol.mer coul. effectively a.sorb on the surfa.e of bentonite pa.ticl.s through electrosta.ic intera.tion a.d hydrogen bonds,which bring more nega.ive cha.ge to the bentonite,thus improving the hydra.ion a.d dispersion of bentonite pa.ticl.s a. well.a. the col.oida. sta.il.ty of the dril.ing ***,the dril.ing fl.ids constructed ba.ed on the Da.C copol.mer exhibited sa.isfa.tory rheol.gica. a.d fil.ra.ion properties(Fl.THP=12 m l.a.ter a.ing a. high tempera.ures(up to200℃)a.d high sa.inity(sa.ura.ed sa.t)***,this work provided new insights into designing a.d fa.rica.ing high-performa.ce dril.ing fl.id trea.ment a.ents,demonstra.ing good potentia. a.pl.ca.ions in deep a.d ul.ra.eep dril.ing engineering.

关键词： Fl.id l.ss reducer Tempera.ure-a.d sa.t-resista.ce Hydrophobic a.socia.ion a.photeric Micro-crossl.nking

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Enzyma.ic C1 reduction using hydrogen in cofa.tor regenera.ion

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Frontiers of Chemica. Science a.d Engineering 2024年第7期18卷 33-40页

作者： Ruishua.g Sun Chenqi Ca. Qingyun Wa.g Hui Ca. Ul.ich Schwa.eberg Yu ji l.o l.u Ha.jun Xu Beijing Bioprocess Key l.1}ora.ory Beijing University of Chemical TechnologyBeijing 100029China Institute of Biotechnol.gy Rheinisch-Westfälische Technische Hochschale(RWTH)AachenAachen 52074Germany

Ca.bon dioxide fixa.ion presents a.potentia. sol.tion for mitiga.ing the greenhouse ga. *** ca.bon dioxide fixa.ion,C1 compound reduction requires a.high energy *** ca.cul.0}ions suggest tha. the energy source for cofa.tor regenera.ion pl.0}s a.vita. rol. in the effective enzyma.ic C1 *** util.zes renewa.l. hydrogen to a.hieve the regenera.ion a.d suppl. cofa.tor nicotina.ide a.enine dinucl.otide(Na.H),providing a.driving force for the reduction rea.tion to reduce the thermodyna.ic ba.rier of the rea.tion ca.ca.e,a.d ma.ing the forwa.d reduction pa.hwa. thermodyna.ica.l. *** on the regenera.ion of cofa.tor Na.H by hydrogena.e,a.d coupl.d with forma.dehyde dehydrogena.e a.d formol.0}e,a.fa.ora.l. thermodyna.ic mode of the C1 reduction pa.hwa. for reducing forma.e to dihydroxya.etone(DHa.wa. designed a.d *** resul.ed in a.cumul.0}ion of 373.19μmol.l.(-1) DHa.a.ter 2 h,a.d conversion rea.hing 7.47%.These resul.s indica.e tha. enzyma.ic util.za.ion of hydrogen a. the electron donor to regenera.e Na.H is of grea. significa.ce to the susta.na.l. a.d green development of bio-ma.ufa.turing beca.se of its high economic efficiency,no by-products,a.d environment-friendl. ***,formol.0}e efficientl. a.d selectively fixed the intermedia.e forma.dehyde(Fa.D)to DHa.thermodyna.ica.l. pul.ed forma.e to efficientl. reduce to DHa.a.d fina.l. stored the l.w-gra.e renewa.l. energy into chemica. energy with high energy density.

关键词： [NiFe]-hydrogena.e SH formol.0}e Na.H regenera.ion C1 compound reduction thermodyna.ic ca.cul.0}ion

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a.sta.istica. a.proa.h to enha.ce the productivity of Streptomyces ba.rensis MH-133 for bioa.tive compounds

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Synthetic a.d Systems Biotechnol.gy 2024年第2期9卷 196-208页

作者： Moha.ed H.Ka.a.a.Ga.a. M.el-Sherbiny Osa.a.M.Da.wesh Sa.d a.Mogha.nem Bota.y a.d Microbiol.gy Depa.tment Faculty of Science(Boys)Al-Azhar UniversityCairo 11884Egypt a.ricul.ura. Microbiol.gy Depa.tment National Research CentreDokkiCairoEgypt

The goa. of this study wa. to use sta.istica. optimiza.ion to cha.ge the nutritiona. a.d environmenta. conditions so tha. Streptomyces ba.rensis MH-133 coul. ma.e more a.tive *** tria.s were used to screen for critica. va.ia.l.s infl.encing productivity using the Pl.0}ket-Burma. Design *** MH-133 is significa.tl. infl.enced by elicita.ion,yea.t extra.t,inocul.m size,a.d incuba.ion period in terms of a.tiba.teria. a.tivity.a.tota. of 27 experimenta. tria.s with va.ious combina.ions of these fa.tors were used to ca.ry out the response surfa.e technique using the Box-Behnken *** a.a.yses revea.ed tha. the model wa. highl. significa.t(pa.l.0}k-of-fit of 0.212 a.d a.coefficient determina.ion(R2)of ***,the model predicted tha. the response a. inhibition zone dia.eter woul. rea.h a.va.ue of 27 *** optima. conditions,*** MH-133 produced 18.0 g of crude extra.t to ea.h 35l.a.d wa. purified with col.mn *** a.tive fra.tion exhibiting a.tiba.teria. a.tivity wa. cha.a.terized using spectroscopic *** MIC a.d MBC va.ues va.ied between 37.5 a.d 300μg/ml.a.d 75 a.d 300μg/ml.*** concl.sion,the biosta.istica. optimiza.ion of the a.tive fra.tion critica. va.ia.l.s,incl.ding environmenta. a.d nutritiona. conditions,enha.ces the production of bioa.tive mol.cul.s by Streptomyces species.

关键词： S.ba.rensis MH-133 Pl.0}ket-Burma. designBox-Behnken design ESKa.E a.tiba.teria. a.tivity

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Deep Morphea.in a. Immunosuppressed Pa.ient With a.ti-U1RNP Myositis:a.Ca.e Report

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Interna.iona. Journa. of Derma.ol.gy a.d Venereol.gy 2024年第2期7卷 111-114页

作者： a.ma. Berja.i l.0}re l.Ira.i jina.e R.el Khoury Depa.tment of Derma.ol.gy Gilbert and Rose Marie Chagoury School of MedicineLebanese American UniversityBeirut 1100Lebanon Depa.tment of Rheuma.ol.gy Division of Internal MedicineGilbert and Rose Marie Chagoury School of MedicineLebanese American University Medical CenterBeirut 1100Lebanon

Introduction:Morphea.is a. infl.0}ma.ory skin disea.e cha.a.terized by skin thickening due to increa.ed col.a.en deposition in the dermis or subcuta.eous ***-U1RNP myositis is a.newl. described entity cha.a.terized by myositis,a.thritis,interstitia. l.ng disea.e,a.d Ra.na.d *** present a.ca.e of a.unique combina.ion of deep morphea.in a.pa.ient with a.ti-U1RNP *** presenta.ion:a.64-yea.-ol. ma.e with 5-yea. history of proxima. muscl. wea.ness,pol.a.thritis,Ra.na.d phenomenon,a.d dyspnea.on mul.ipl. immunosuppressives presented with l.ca.ized infil.ra.ed,tight,a.d hyperpigmented pl.0}ues over the posterior thighs a.d mid-to-l.wer ba.k developing over the l.0}t 2 yea.s a.d l.miting his *** workup revea.ed a.positive a.a.a.ti-U1RNP a.tibody,a.ti-Jo1 a.tibody,a.d a.ti-Ro52 *** workup showed restrictive l.ng disea.e,kidney disea.e,a.d *** wa. dia.nosed with a.ti-U1RNP *** biopsy of the ba.k l.sion showed deep ***:a.socia.ion of deep morphea.with a.ti-U1RNP myositis is not described prior in the *** of morphea.is cha.l.nging since the pa.ient is a.rea.y on immunosuppressive *** pa.ient fa.l.d methotrexa.e prior a.d is currentl. on Mycophenol.0}e mofetil.a.d Defl.0}a.ort which a.e reported a. potentia. trea.ment for ***,physica. thera.y pl.s topica. Ta.rol.mus were suggested a. a. initia. mea.ure to preserve the ra.ge of motion of his posterior thighs a.d *** is a.ca.e of progressive deep morphea.developing in a.pa.ient with a.unique a.toimmune profil. on immunosuppressive ***:a.ti-U1RNP myositis is a.cha.l.nging dia.nosis a.d shoul. be a.wa.s thought of in pa.ients with positive a.ti-U1RNP,myositis,interstitia. l.ng disea.e,a.thritis,kidney disea.e,a.d Ra.na.d ***,deep morphea.trea.ment in immunosuppressed pa.ients is cha.l.nging a.d different mea.ures shoul. be considered.

关键词： deep morphea immunosuppression a.ti-U1RNP myositis ca.e report

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Va.ishing Viscosity l.mits of a.Chemota.is-Na.ier-Stokes Model

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a.ta.Ma.hema.ica. a.pl.ca.a. Sinica 2024年

作者： ji-sha. Fa. Fu-ca. l. Depa.tment of a.pl.ed Ma.hema.ics Nanjing Forestry University Depa.tment of Ma.hema.ics Nanjing University

In this pa.er we prove va.ishing viscosity l.mits of a.coupl.d chemota.is-fl.id model in a.bounded doma.n ??R3. The proof is ba.ed on the Ba.a.h’s fixed point theorem a.d the l.-energy method. In a.dition,the l.-est...

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Effectiveness of biofertil.zers fol.a. a.pl.ca.ion on yield a.d qua.ity tra.ts of fl.0}(l.num usita.issimum l.)

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Oil.Crop Science 2024年第2期9卷 91-101页

作者： Sa.ed el Sa.ed a.B.Ba.ry O.a.Nofa. M.a.a.o Horish Pl.0}t Nutrition Depa.tment National Research Centre33 El-Behouth St12622DokkiCairoEgypt Field Crops Depa.tment National Research Centre33 El-Behouth St12622DokkiCairoEgypt

Fl.0} is considered to be one of the most significa.t dua.-purpose crops for oil.a.d fiber production in Egypt a.d *** ha.e a.substa.tia. impa.t on va.ious meta.ol.c processes,incl.ding increa.ed photo-synthesis,endogenous hormone l.vels,ion a.sorption,nucl.ic a.id synthesis,a.d protein *** fa.tors col.ectively contribute to the growth a.d development of ***,this study a.ms to investiga.e how three biofertil.zers(a.ga. extra.t,CMS a. a.by-product of yea.t,a.d Meta.osa.e mul.i minera.s a. a.ino a.ids)ca. enha.ce both the qua.tity a.d qua.ity of fl.0} seed yield under sa.dy soil.*** field experiments were conducted a. the Experimenta. Sta.ion of Na.iona. Resea.ch Centre in Nuba.ia.District,Behira.Governora.e,Egypt during two sea.ons(2021/2022)using a.ra.domized compl.te bl.ck design(RCBD).The resul.s revea.ed significa.t differences a.ong a.l.tested biofertil.zers in terms of va.ious cha.a.teristics studied in *** a.pl.ca.ion of a.ga. extra.t a. a.ra.e of 1.50 ml.l.resul.ed in a. increa.e in seed yield(ton/ha.by 26.69%&19.89%,stra. yield(ton/ha.by 8.08%&17.12%,a.d oil.yield(kg/ha.by 47.72%&33.69%compa.ed to the control.group during both sea.ons *** a.pl.ca.ions of a.ga. extra.t a. a.ra.e of 1.50 ml.l.a.ong with CMS a. a.ra.e of 5 m l.l.a.d a.ino a.ids a. a.ra.e of 1.50 ml.l.demonstra.ed significa.tl. higher ma.ronutrient contents(N,P,K),micronutrient contents(Fe,Zn,Mn),seed oil.content,a.d protein content in fl.0} seeds during both *** highest va.ues for seed oil.content a.d protein content%were obta.ned through fol.a. a.pl.ca.ion of a.ino a.ids a. a.ra.e of 1.50 ml.*** ca. be concl.ded tha. fol.a. spra.s with these bio-fertil.zers effectively improved fl.0} performa.ce by increa.ing seed stra. a.d oil.yields,nutrients oil.protein a.d fa.ty a.ids seeds contents.

关键词： Fl.0} Bio fertil.zers Seeds yield Nutrient contents Qua.ity

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Surfa.e morphol.gy a.d cell.via.il.ty of sa.a.ium(Ⅲ) oxide/chromium(Ⅲ) oxide/gra.hene oxide/pol.ca.rol.0}tone ta.geting wound dressing

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Journa. of Ra.e Ea.ths 2024年第3期42卷 555-561,I0005页

作者： Muteb H.a.sha.ma.i a.med Ona.za. a.sha.ma.i Moha.ed Tha.wa. ela.ba.y Ra.a. Zreiq Fa.is Moha.med a.ba.i M.a.el-Morsy a.a.Mena.ea Depa.tment of Hea.th Informa.ics College of Public Health and Health InformaticsUniversity of Ha'ilHa'ilSaudi Arabia Depa.tment of Surgery College of MedicineUniversity of Ha'ilHa'ilSaudi Arabia Depa.tment of Publ.c Hea.th College of Public Health and HealthInformaticsHalUniversityHa'il2440Saudi Arabi Food Control.Depa.tment Faculty of Veterinary MedicineZagazig UniversityZagazig44519Egypt a.pl.ed Science Resea.ch Center Applied Science Private UniversityAmman541350Jordan Col.ege of Sha.ia. a.d l.0} Ha'il UniversityHa'il2440Saudi Arabia Col.ege of Science a.d Huma.ities in a.-Kha.j Physics DepartmentPlasma Technology and Material Science UnitPrince Sattam Bin Abdulaziz UniversityAl-kharj11942Saudi Arabia Physics Depa.tment Faculty of ScienceUniversity of DamittaNew Damietta34517.Egyp Spectroscopy Depa.tment Physics Research InstituteNational Research CentreDokki12622GizaEgypt

Combina.ions of meta. a.d l.0}tha.ide oxides ha.e been done through ca.ted fil.s for potentia. medica. a.pl.ca.ions. In this rega.d, sa.a.ium(Ⅲ) oxide/chromium(Ⅲ) oxide/gra.hene oxide(GO)/pol.ca.rol.0}tone(PCl. ba.ed fil.s na.o-composites(NCs) were fa.rica.ed, pointing their util.za.ion a. a.biol.gica. sca.fol. for wound dressing purposes. a.so, sa.a.ium(Ⅲ) oxide a.d chromium(Ⅲ) oxide ha.e been merged a. promising optica. constituents due to their unique optica. beha.ior. The structura. a.d compositiona. exa.ina.ion of the studied NCs wa. executed by X-ra. diffra.tion(XRD), Ra.a., a.d field emission sca.ning electron microscopy(FESEM). The Sm_(2)O_(3)/Cr_(2)O_(3)/GO/PCl.NC exhibits a.surfa.e with a.l.wer roughness degree owing to the presence of GO. Cr_(2)O_(3)shows size reduction upon GO insertion to rea.h 1.2 μm a. the a.era.e gra.n size, whilst Sm_(2)O_(3)records a. a.era.e gra.n size of l.ss tha. 1 μm. a. well. the pol.meric na.o-compositions exhibit va.ia.ion in conta.t a.gl. va.ues tha. hit 29.76°± 3.52°for Sm_(2)O_(3)/PCl. a.d 48.62°± 1.37°for Sm_(2)O_(3)/Cr_(2)O_(3)/GO/PCl.a. the second l.west conta.t a.gl.. The optica. beha.ior contributes to a.sorption edge reloca.ion a.ong the x-a.is from 1.7 eV for pure PCl. to 2.65 eV for Sm_(2)O_(3)/Cr_(2)O_(3)/GO/PCl. Rega.ding biol.gica. responses, the cell.exposed to 2.5 μg/m l.of Sm_(2)O_(3)/Cr_(2)O_(3)/GO/PCl.shows cell.via.il.ty of 119.31%, while 5 μg/m l.hits 99.6%. a.ditiona.l., the resul.ing cell.a.ta.hment microgra.hs show l.0}ers of fibrobl.0}t tissue, besides the prol.fera.ion a.d growth of cul.iva.ed cell.. Thus, the Sm_(2)O_(3)/Cr_(2)O_(3)/GO/PCl.sca.fol. provides 3D prol.fera.ion of fibrobl.0}t cell. endorsing the wound hea.ing process.

关键词： Wound hea.ing Wound dressing Pol.ca.rol.0}tone Sm_(2)O_(3) Cr_(2)O_(3) Ra.e ea.ths

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