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Impact of postoperative TNM stages after neoadjuvant therapy on prognosis of adenocarcinoma of the gastro-oesophageal junction tumours

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World Journal of Gastroenterology 2018年第13期24卷 1429-1439页

作者： Michael Thomaschewski Richard Hummel ekaterina Petrova Juliana Knief Ulrich Friedrich Wellner Tobias Keck Dirk Bausch Department of Surgery University Medical Center Schleswig-Holstein Campus Lübeck Department of Pathology University Medical Center Schleswig-Holstein Campus Lübeck

AIM To compare prognostic relevance of postoperative tumour/node/metastasis(TMN) stages between patients with and without neoadjuvant treatment. METHODS Data from patients with adenocarcinoma of the gastrooesophageal junction(AEG) who had undergone surgical resection at a single German university centre were retrospectively analysed. Patients with or without neoadjuvant preoperative treatment were selected by exact matching based on preoperative staging. Standard assessment of preoperative(c)TNM stage was based on endoscopic ultrasound and computed tomography of the thorax and abdomen, according to the American Joint Committee on Cancer/Union for International Cancer Control classification system. Patients with cT1cN0cM0 and cT2cN0cM0 stages were excluded from the study, as these patients are generally not recommended for pretreatment. Longterm survival among the various postoperative TNM stages was compared between the groups of patients with or without neoadjuvant treatment. For statistical assessments, a P-value of ≤ 0.05 was considered *** The study included a total of 174 patients. The group of patients who had received preoperative neoadjuvant treatment included more cases of AEG(Siewert) type 1 carcinoma(P < 0.001), and consequently oesophagectomy was performed more frequently among these patients(P < 0.001). The two groups(with or without preoperative neoadjuvant treatment) had comparable preoperative T stages, but the group of patients with preoperative neoadjuvant treatment presented a higher rate of preoperative N-positive disease(P = 0.020). Overall long-term survival was not different between the two groups of patients according to tumours of different AEG classifications, receipt of oesophagectomy or gastrectomy, nor between patients with similar postoperative TNM stage, resection margin and grading. However, an improvement of long-term survival was found for patients with nodal down-staging after neoadjuvant therapy(P = 0.053).CONCLUSI

关键词： Adenocarcinoma of the gastro-oesophageal junction American Joint Committee on Cancer/Union for International Cancer Control TNM system Neoadjuvant therapy Oesophageal cancer

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Rational Design of Titanium Carbide MXene Electrode Architectures for Hybrid Capacitive Deionization

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Energy & Environmental Materials 2020年第3期3卷 398-404页

作者： Samantha Buczek Michael L.Barsoum Simge Uzun Narendra Kurra Ryan Andris ekaterina Pomerantseva Khaled A.Mahmoud Yury Gogotsi Department of Materials Science and Engineering and A.J.Drexel Nanomaterials Institute Drexel UniversityPhiladelphia PA 19104USA Qatar Environment and Energy Research Institute(QEERI) Hamad Bin Khalifa University(HBKU)P.O.Box 34110Doha Qatar

Intercalation redox materials have shown great promise for efficient water desalination due to available faradaic gallery *** capacitive deionization(CDI)cells previously demonstrated using MXenes were often limited in their salt adsorption capacity(SAC)and voltage window of *** this study,current collector-and binder-free Ti3C2Tx MXene electrode architectures are designed with porous carbon as the positive electrode to demonstrate hybrid CDI(HCDI)***,MXene current collectors are fabricated by employing a scalable doctor blade coating technique and subsequently spray coating a layer of a small flake MXene *** redox-active galleries of MXenes are capable of intercalating a variety of aqueous cations including Na+,K+,and Mg2+ions,showing volumetric capacitances up to 250 F *** a result,a salt removal capacity of 39 mg g-1 with decent cycling stability is *** study opens new avenues for developing freestanding,binder-and additivefree MXene electrodes for HCDI applications.

关键词： MXene bi-stacked design water desalination purification CDI

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Effect of Zr^(4+)on piezoelectric,dielectric and ferroelectric properties of barium calcium titanate lead-free ceramics

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Journal of Advanced Dielectrics 2021年第6期11卷 23-31页

作者： Prasanta Kumar Panda Benudhar Sahoo V.Sureshkumar ekaterina Dmitrievna Politova Materials Science Division CSIR-National Aerospace Laboratories KodihalliBengaluru 560017India Semenov Federal Research Centre for Chemical Physics Russian Academy of Sciences Kosygin 4Moscow 119991Russia

Ba_(0.85)Ca_(0.15)(Ti1−xZrx)O_(3)(BCTZ)ceramics with x=0.05,0.10,_(0.15),0.20,0.25,0.30 were prepared by the solid-state reaction *** of the powders was carried out at 1100°C for 4 h and the green pellets were sintered at 1400°C for 2 h.X-ray diffraction patterns of the sintered pellets showed tetragonal splitting up to x=0.10 while the mixture of the rhombohedral/cubic phase appeared at higher ZrO_(2)*** piezoelectric charge constant d33=510 pC/N and strain(S=0.103%)were measured for BCT doped by 0.10 mol ZrO_(2).Dielectric constant,remnant polarization and saturation polarization also found maxima for this *** Curie temperature(TC)of the compositions decreased with increase in ZrO_(2)concentration and reached 98°C,87°C and 36°C at x=0.05,0.10,_(0.15)mol,*** remaining compositions have TC below the room temperature;therefore,they can be used for subzero/cryogenic *** scanning electron microscopy study revealed an increase in grain size with increase in ZrO_(2)concentration and confirmed the complete solubility of ZrO_(2)in the crystal ***,low ZrO_(2)-doped BCT compositions with high d33 could be suitable for low temperature(<80°C)applications.

关键词： ZrO_(2)-doped BCT lead-free piezoelectrics high piezoelectric charge constant Curie temperature

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Selective sPlenic flExure mobilization for low colorEctal anastomosis after D3 lYmph node dissection (SPEEDY) trial: a study protocol

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Chinese Medical Journal 2020年第15期133卷 1884-1885页

作者： Petr Tsarkov Tatiana Garmanova Victor Zhurkovskiy Daniil Markaryan Lyudmila Sidorova Arcangelo Picciariello ekaterina Kazachenko Inna Tulina Clinic of Colorectal and Minimally Invasive Surgery Sechenov First Moscow State Medical UniversityMoscow 101000Russian Federation Department of Emergency and Organ Transplantation University of BariBari 70100Italy Sechenov First Moscow State Medical University Moscow 101000Russian Federation

To the Editor:Colorectal cancer(CRC)remains the second most frequent cause of cancer-related deaths *** the concept of total mesorectal excision(TME)introduced by Heald et al[1] has become a gold standard of rectal cancer surgery,there has been a significant improvement in oncological outcomes including diseasefree and overall survival.

关键词： cancer dissection anastomosis

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Cell surface engineering with polyelectrolyte-stabilized magnetic nanoparticles： A facile approach for fabrication of artificial multicellular tissue-mimicking clusters

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Nano Research 2015年第8期8卷 2515-2532页

作者： Maria R. Dzamukova ekaterina A. Naumenko Elvira V. Rozhina Alexander A. Trifonov Rawil F. Fakhrullin Bionanotechnology Lab Institute of Fundamental Medicine and Biology Kazan Federal University Kreml uraml 18 Kazan 420008Republic of Tatarstan Russian Federation

Regenerative medicine requires new ways to assemble and manipulate cells for fabrication of tissue-like constructs. Here we report a novel approach for cell surface engineering of human cells using polymer-stabilized magnetic nanoparticles （MNPs）. Cationic polyelectrolyte-coated MNPs are directly deposited onto cellular membranes, producing a mesoporous semi-permeable layer and rendering cells magnetically responsive. Deposition of MNPs can be completed within minutes, under cell-friendly conditions （room temperature and physiologic media）. Microscopy （TEM, SEM, AFM, and enhanced dark-field imaging） revealed the intercalation of nanoparticles into the cellular microvilli network. A detailed viability investigation was performed and suggested that MNPs do not inhibit membrane integrity, enzymatic activity, adhesion, proliferation, or cytoskeleton formation, and do not induce apoptosis in either cancer or primary cells. Finally, magnetically functionalized cells were employed to fabricate viable layered planar （two-cell layers） cell sheets and 3D multicellular spheroids.

关键词： magnetic nanoparticles artificial multicelluar clusters magnetic modification

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A simple method to model the reduced environment of lake bottom sapropel formation

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Chinese Journal of Oceanology and Limnology 2017年第4期35卷 956-966页

作者： Olga L.GASKOVA Vera D.STRAKHOVENKO Nadezhda I.ERMOLAEVA Eugene Yu.ZARUBINA ekaterina A.OVDINA V.S.Sobolev Institute of Geology and Mineralogy Siberian Branch of the Russian Academy of Sciences Novosibirsk State University Institute for Water and Environmental Problems Siberian Branch of the Russian Academy of Sciences

The Kambala and Barchin brackish lakes （Baraba steppe, southern West Siberia） contain an organic-rich sapropel layer that was formed in oxygen-depleted waters. We measured the bulk sediment elemental composition, the water chemistry and determined the mineralogical composition and predominant biota species （Diatoms and Cyanobacteria in phytoplankton community respectively） in the lakes. The result indicates that the first lake has a siliceous type of sapropel and the second a carbonaceous one. A computer thermodynamic model was developed for chemical interaction in water-bottom sediment systems of the Kambala and Barchin Lakes. The surface sodium bicarbonate waters are supersaturated with respect to calcite, magnesite （or low Mg-calcite）, quartz and chlorite with minor strontianite, apatite and goethite （pH 8.9-9.3, Eh 0.3 V）. Nevertheless, it is shown that during sapropel deposition, deep silt waters should be anoxic （Eh〈0 V）. The virtual component CH20 has been used to create an anoxic environment suitable for pyrite formation due to the biotic community impact and abiotic reduction. Thermodynamic calculation has shown that silt water is not necessarily euxinic （anoxic and sulfidic）. Depending on Eh, sulfate sulfur can dominate in solution, causing the formation of gypsum together with pyrite. An attempt was made to find a reason for solution supersaturation with respect to Ca and Mg ions due to their complexation with humic acids.

关键词： brackish lakes sapropel sediments mineral composition silica calcite thermodynamic calculations

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Photocatalytic Treatment of Waste Water from Rice Husk Alkaline Hydrolysate

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Rice science 2019年第4期26卷 257-260页

作者： Olga D. AREFIEVA Marina S. VASILYEVA ekaterina V. ERMOLENKO Anastasiia V. BYCHKOVA Far Eastern Federal University Vladivostok 690950Russian Federation Institute of Chemistry Far-Eastern BranchRussian Academy of Sciences Vladivostok 690022 Russian Federation National Scientific Center of Marine Biology Far Eastern BranchRussian Academy of SciencesVladivostok 690041Russian Federation

We carried out photocatalytic treatment of a lignin-free solution of rice husk alkaline hydrolysate [pH of 2, chemical oxygen demand（COD） of 12.8 g/L] using photo-Fenton process in the ultraviolet（UV, wavelength of 365 nm） and visible spectrum. Oxidation of lignin was performed at a constant mass ratio of COD:H2O2 as 1:2 and Fe2+ concentration of 80 mg/L. It was established that for the destruction of alkaline lignin, exposure to visible or UV radiation was necessary. Decolorization efficiency of a lignin-free solution depends on the dilution rate of the solution. The advanced oxidative photo-Fenton process(UV/Н2О2/Fe2+) made it possible to reduce the color of lignin-free solution at a dilution ratio of 1:5 by 94% of decolorization efficiency, 87% of phenolic compound and 79% of COD. With the help of gas chromatography, the products of lignin destruction were low-toxic and usable.

关键词： chemical oxygen demand dilution ratio visible spectrum

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In vivo degradability and biocompatibility of a rheo-formed Mg–Zn–Sr alloy for ureteral implantation

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Journal of Magnesium and Alloys 2022年第6期10卷 1631-1639页

作者： Di Tie Renguo Guan Huinan Liu Minfang Chen Sviatlana A.Ulasevich ekaterina V.Skorb Patricia Holt-Torres Xiaopeng Lu Norbert Hort Engineering Research Center of Continuous Extrusion Ministry of EducationDalian Jiaotong UniversityDalian 116028China School of Materials Science and Engineering Northeastern UniversityShenyang 110819China Department of Bioengineering University of CaliforniaRiversideCA 92521USA School of Materials Science and Engineering Tianjin University of TechnologyTianjin 300384China Infochemistry Scientific Center ITMO UniversitySt.Petersburg 192007Russia Magnesium Innovation Center-MAGIC Helmholtz Zentrum GeesthachtGeesthacht D-21502Germany

The introduction of biodegradable implant materials has significantly improved the postoperative subjective feelings of patients within the past few decades,among which magnesium alloy is widely considered a favorable choice as its appropriate biodegradability and evident antibacterial ***,we reveal a semisolid rheo-formed Mg–Zn–Sr alloy ureteral implant that displayed suitable degradability and biocompatibility in a pig *** non-dendritic microstructure was observed in the rheo-formed alloy,which led to ca.47%increase in ultimate tensile strength(from 195.0 MPa to 288.1 MPa)and more homogeneous degradation process compared with the untreated *** post-interventional inflammation or pathological changes of the test animals were observed during the implantation period,and the corrosion rate(0.22±0.04 mm·y^(-1))perfectly fitted the clinical ureteral stent indwelling *** urine bacteria numbers decreased from 88±13 CFU·mL^(-1)at 7 weeks post operation to 59±8 CFU·mL^(-1)at 14 weeks post operation,which confirmed the evident antibacterial activity of the *** study demonstrates that the Mg–Zn–Sr alloy is clinically safe for urinary system,enabling its efficacious use as ureteral implant materials.

关键词： In vivo Biodegradability Biocompatibility Mg–Zn–Sr alloy Ureteral implant

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Influence of the operating temperature on the ageing and interfaces of double layer polymer electrolyte solid state Li metal batteries

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Nano Research 2023年第6期16卷 8377-8384页

作者： Mikel Arrese-Igor María Martinez-Ibañez Ander Orue ekaterina Pavlenko Erwan Dumont Michel Armand Frédéric Aguesse Pedro López Aranguren Centre for Cooperative Research on Alternative Energies(CIC energiGUNE) Basque Research and Technology Alliance(BRTA)Alava Technology ParkAlbert Einstein 48Vitoria-Gasteiz 01510Spain University of the Basque Country(UPV/EHU) Barrio Sarrienas/nLeioa 48940Spain Saft 111 Boulevard Alfred DaneyBordeaux Cedex 33074France

Solid-state lithium metal batteries(SSLMBs)are considered an auspicious technology to develop high energy density and safe energy storage *** double layer polymer electrolyte(DLPE)is a rational approach for engineering high-performance SSLMBs addressing electrolyte requirements with specifically designed polymers at the positive electrode and as *** this work,SSLMBs were assembled with poly(propylene carbonate)(PPC),offering stability toward oxidation at the positive electrode,and a gel polymer electrolyte with polyethyleneglycol dimethylether(PEGDME)as separator,offering high ionic conductivity at low temperature and sufficient interfacial stability with Li *** electrochemical properties and performance of cells with LiFePO_(4) and Li[Ni_(0.6)Mn_(0.2)Co_(0.2)]O_(2) positive electrodes are thoroughly investigated as function of the operating temperature by using a host of characterization ***-voltage cells with an areal capacity of 0.7 mAh·cm^(−2)cycled at 40℃ exhibit a higher capacity retention than the cells cycled at 70℃.To understand such differences,a three-electrode setup is applied to discriminate anodic processes from cathodic as function of the *** elucidate the ageing and interfacial evolution for DLPE cells with gel polymer electrolytes paving the way for building performance solid state batteries.

关键词： double layer polymer electrolyte solid-state lithium metal battery gel polymer electrolyte high voltage interfacial study

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Algebraic Cryptanalysis of GOST Encryption Algorithm

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Journal of Computer and Communications 2014年第4期2卷 10-17页

作者： Ludmila Babenko ekaterina Maro Department of Information Security Southern Federal University Taganrog Russia

This paper observes approaches to algebraic analysis of GOST 28147-89 encryption algorithm (also known as simply GOST), which is the basis of most secure information systems in Russia. The general idea of algebraic analysis is based on the representation of initial encryption algorithm as a system of multivariate quadratic equations, which define relations between a secret key and a cipher text. Extended linearization method is evaluated as a method for solving the nonlinear sys- tem of equations.

关键词： Encryption Algorithm GOST GOST S-Box Systems of Multivariate Quadratic Equations Algebraic Cryptanalysis Extended Linearization Method Gaussian Elimination

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