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Food contaminants and potential risk of diabetes development:A narrative review

World Journal of Diabetes 2023年第6期14卷 705-723页

作者： Maja Milanovic Natasa Milosevic Natasa Milic Milica Medic Stojanoska edward petri Jelena Markovic Filipovic Department of Pharmacy Faculty of MedicineUniversity of Novi SadNovi Sad 21000Serbia Faculty of Medicine Clinic for EndocrinologyDiabetes and Metabolic DiseasesUniversity Clinical Center of VojvodinaUniversity of Novi SadNovi Sad 21000Serbia Department of Biology and Ecology Faculty of SciencesUniversity of Novi SadNovi Sad 21000Serbia

The number of people diagnosed with diabetes continues to increase,especially among younger *** from genetic predisposition and lifestyle,there is increasing scientific and public concern that environmental agents may also contribute to *** contamination by chemical substances that originate from packaging materials,or are the result of chemical reactions during food processing,is generally recognized as a worldwide problem with potential health ***,bisphenol A(BPA)and acrylamide(AA)have been the focus of attention in recent years,due to the numerous adverse health effects associated with their *** paper summarizes the available data about the association between phthalates,BPA and AA exposure and *** their mechanism of action has not been fully clarified,in vitro,in vivo and epidemiological studies have made significant progress toward identifying the potential roles of phthalates,BPA and AA in diabetes development and *** chemicals interfere with multiple signaling pathways involved in glucose and lipid homeostasis and can aggravate the symptoms of *** concerning are the effects of exposure during early stages and the gestational ***-designed prospective studies are needed in order to better establish prevention strategies against the harmful effects of these food contaminants.

关键词： Acrylamide Bisphenol A Phthalates Endocrine disrupting chemicals β-cell Diabetes

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