Food contaminants and potential risk of diabetes development:A narrative review

作     者：Maja Milanovic Natasa Milosevic Natasa Milic Milica Medic Stojanoska Edward Petri Jelena Markovic Filipovic 

作者机构：Department of PharmacyFaculty of MedicineUniversity of Novi SadNovi Sad 21000Serbia Faculty of MedicineClinic for EndocrinologyDiabetes and Metabolic DiseasesUniversity Clinical Center of VojvodinaUniversity of Novi SadNovi Sad 21000Serbia Department of Biology and EcologyFaculty of SciencesUniversity of Novi SadNovi Sad 21000Serbia 

出 版 物：《World Journal of Diabetes》 (世界糖尿病杂志（英文版）（电子版）)

年 卷 期：2023年第14卷第6期

页      面：705-723页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 100403[医学-营养与食品卫生学] 10[医学] 

基　　金：Supported by the Ministry of Education,Science and Technological Development of the Republic of Serbia,451-03-68/2022-14/200125 Provincial Secretariat for Higher Education and Scientific Research,AP Vojvodina,Republic of Serbia,142-451-3120/2022-01 

主　　题：Acrylamide Bisphenol A Phthalates Endocrine disrupting chemicals β-cell Diabetes 

摘      要：The number of people diagnosed with diabetes continues to increase,especially among younger *** from genetic predisposition and lifestyle,there is increasing scientific and public concern that environmental agents may also contribute to *** contamination by chemical substances that originate from packaging materials,or are the result of chemical reactions during food processing,is generally recognized as a worldwide problem with potential health ***,bisphenol A(BPA)and acrylamide(AA)have been the focus of attention in recent years,due to the numerous adverse health effects associated with their *** paper summarizes the available data about the association between phthalates,BPA and AA exposure and *** their mechanism of action has not been fully clarified,in vitro,in vivo and epidemiological studies have made significant progress toward identifying the potential roles of phthalates,BPA and AA in diabetes development and *** chemicals interfere with multiple signaling pathways involved in glucose and lipid homeostasis and can aggravate the symptoms of *** concerning are the effects of exposure during early stages and the gestational ***-designed prospective studies are needed in order to better establish prevention strategies against the harmful effects of these food contaminants.