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Storylines of family medicine Ⅹ:standing up for diversity,equity and inclusion

Family Medicine and Community Health 2024年第S3期12卷 89-98页

作者： William B Ventres Leslie A Stone Wayne W Bryant jr.Mario F Pacheco Edgar Figueroa Francis N Chu Shailendra Prasad David N Blane Na'amah Razon Ranit Mishori Robert L Ferrer Garrett S Kneese Family and Preventive Medicine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA Family and Community Medicine University of New Mexico School of MedicineAlbuquerqueNew MexicoUSA Medicine Weill Cornell Medical CollegeNew YorkNew YorkUSA San Jose Family Medicine Residency Kaiser PermanenteSan JoseCaliforniaUSA Family Medicine and Community Health University of Minnesota Medical School—Twin Cities CampusMinneapolisMinnesotaUSA School of Health and Wellbeing University of GlasgowGlasgowUK Family and Community Medicine University of CaliforniaDavisSacramentoCaliforniaUSA Family Medicine Georgetown University School of MedicineWashingtonDistrict of ColumbiaUSA Family and Community Medicine UT Health San Antonio Long School of MedicineSan AntonioTexasUSA UC San Diego Family Medicine Residency Program San DiegoCaliforniaUSA

Storylines of Family Medicine is a 12-part series of thematically linked mini-essays with accompanying illustrations that explore the many dimensions of family medicine as interpreted by individual family physicians and medical educators in the USA and elsewhere around the ***‘Ⅹ:standing up for diversity,equity and inclusion’,authors address the following themes:‘The power of diversity—why inclusivity is essential to equity in healthcare’,‘Medical education for whom?’,‘Growing a diverse and inclusive workforce’,‘Therapeutic judo—an inclusive approach to patient care’,‘Global family medicine—seeing the world“upside down”’,‘The inverse care law‘,‘Social determinants of health as a lens for care’,‘Why family physicians should care about human rights’and‘Toward health equity—the opportunome’.May the essays that follow inspire readers to promote change.

关键词： illustration education family

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A sensitive electrochemical detection of metronidazole in synthetic serum and urine samples using low-cost screen-printed electrodes modified with reduced graphene oxide and C60

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Journal of Pharmaceutical Analysis 2021年第5期11卷 646-652页

作者： Elsa Maria Materon Ademar Wong Tayane Aguiar Freitas Ronaldo Censi Faria Osvaldo N.Oliveira jr. Department of Chemistry Federal University of Sao Carlos13560-970Sao CarlosBrazil Sao Carlos Institute of Physics University of Sao Paulo13560-970Sao CarlosBrazil

Monitoring the concentration of antibiotics in body fluids is essential to optimizing the therapy and minimizing the risk of bacteria resistance,which can be made with electrochemical sensors tailored with appropriate *** this paper,we report on sensors made with screen-printed electrodes(SPE)coated with fullerene(C60),reduced graphene oxide(rGO)and Nafion(NF)(C60-rGO-NF/SPE)to determine the antibiotic metronidazole(MTZ).Under optimized conditions,the C60-rGO-NF/SPE sensor exhibited a linear response in square wave voltammetry for MTZ concentrations from 2.5×10^(-7) to 34×10^(-6) mol/L,with a detection limit of 2.1×10^(-7) mol/*** sensor was also capable of detecting MTZ in serum and urine,with recovery between 94%and 100%,which are similar to those of the standard chromatographic method(HPLC-UV).Because the C60-rGO-NF/SPE sensor is amenable to mass production and allows for MTZ determination with simple principles of detection,it fulfills the requirements of therapeutic drug monitoring programs.

关键词： Metronidazole Fullerene Reduced graphene oxide Screen-printed electrodes Antibiotic

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Magnetocaloric effect of Pr_2Fe_(17-x)Mn_x alloys

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Rare Metals 2014年第5期33卷 552-555页

作者： Xi-Chun Zhong Zhong-Wu Liu De-Chang Zeng Karl A.Gschneidner jr. Vitalij K.Pecharsky School of Materials Science and Engineering South China University of Technology Ames Laboratory U.S.Department of Energy and Department of Materials Science and Engineering Iowa State University

Polycrystalline Pr2Fe17-xMnx（x = 0, 1, and 2）alloys were studied by X-ray diffraction（XRD）, heat capacity, ac susceptibility, and isothermal magnetization measurements. All the alloys adopt the rhombohedral Th2Zn17-type structure. The Curie temperature increases from 283 K at x = 0 to 294 K at x = 1, and then decreases to 285 K at x = 2. The magnetic phase transition at the Curie temperature is a typical second-order paramagnetic–ferromagnetic transition. For an applied field change from0 to 5 T, the maximum-△SM for Pr2Fe17-xMnxalloys with x = 0, 1, and 2 are 5.66, 5.07, and 4.31 J·kg^-1·K^-1,respectively. The refrigerant capacity（RC） values range from 458 to 364 J·kg^-1, which is about 70 %–89 % that of Gd. The large, near room temperature △SM and RC values,chemical stability, and a high performance-to-cost ratio make Pr2Fe17-xMnxalloys be selectable materials for room temperature magnetic refrigeration applications.

关键词： Pr2Fe17-xMnx alloys Magnetocaloric effect Magnetic entropy change

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Mesenchymal stem cell therapy for acute radiation syndrome: Innovative medical approaches in military medicine

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Journal of Medical Colleges of PLA(China) 2014年第3期29卷 186-195页

作者： Erik B.Eaton jr. Timothy R.Varney United States Army Medical Research Institute of Chemical Defense 3100 Ricketts Point Road Aberdeen Proving GroundMaryland 21010 US United States Army Medical Research Institute of Chemical Defense 3100 Ricketts Point Road Aberdeen Proving Ground Maryland 21010 US

After a radiological or nuclear event, acute radiation syndrome(ARS) will present complex medical challenges that could involve the treatment of hundreds to thousands of patients. Current medical doctrine is based on limited clinical data and remains inadequate. Efforts to develop medical innovations that address ARS complications are unlikely to be generated by the industry because of market uncertainties specific to this type of injury. A prospective strategy could be the integration of cellular therapy to meet the medical demands of ARS. The most clinically advanced cellular therapy to date is the administration of mesenchymal stem cells(MSCs). Results of currently published investigations describing MSC safety and efficacy in a variety of injury and disease models demonstrate the unique qualities of this reparative cell population in adapting to the specific requirements of the damaged tissue in which the cells integrate. This report puts forward a rationale for the further evaluation of MSC therapy to address the current unmet medical needs of ARS. We propose that the exploration of this novel therapy for the treatment of the multivariate complications of ARS could be of invaluable benefit to military medicine.

关键词： Acute radiation syndrome Mesenchymal stem cell Cell therapy Hematopoietic syndrome Gastrointestinal syndrome Radiation injury

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Rotating machinery vibration : +from analysis to troubleshooting / +Maurice L. Adams, jr.

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1000年

作者： Maurice L. Adams jr.

Includes bibliographical references and index.

ISBN: (纸本)9781439807170 (hardcover : alk. paper);1439807175 (hardcover : alk. paper);9781439818701 (pbk.);1439818703 (pbk.)

Includes bibliographical references and index.

关键词： Turbomachines Rotors

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Accounting fundamentals Michael G. Curran, jr. 7th ed.

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2006年

作者： Michael G. Curran jr.

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New venture creation : entrepreneurship for the 21st century Jeffry A. Timmons and Stephen Spinelli, jr. 6th ed.

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2004年

作者： Jeffry A. Timmons and Stephen Spinelli jr.

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Study of the Stock Market Cross-correlation with Cross Sample Entropy

Study of the Stock Market Cross-correlation with Cross Sampl...

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作者： Moses S.E.Hinneh jr. 华东理工大学

学位级别：硕士

本论文中,我们采用跨样本熵值法来调研2004-2011年间市场和行业层面国际股票收益的发展。2007/2009年度全球金融危机用作案例研究。我们探究了中国大陆,香港,德国,日本,英国和美国8个市场指数下2004-2011年间的的每日数据。与此同时,我...

本论文中,我们采用跨样本熵值法来调研2004-2011年间市场和行业层面国际股票收益的发展。2007/2009年度全球金融危机用作案例研究。我们探究了中国大陆,香港,德国,日本,英国和美国8个市场指数下2004-2011年间的的每日数据。与此同时,我们计算了从8个分区（基本材料,金融,医疗,技术,消费品,工业品,服务以及综合部门）选取的8支股票两两之间道琼斯工业平均指数的交互关系。SampEn（样本熵）可靠区间的计算方法延伸到cross-SampEn（跨样本熵）。2004-2007期间（全球金融危机前）以及2008-2011（全球金融危机后）每两支股票之间的cross-SampEn以及可靠区间也计算了。样本计算方法用在选取的证券指数中。结果表明这些市场指数的cross-SampEn在全球金融危机后减小,这暗示较低的不同时性（与金融危机有相关性）。与此同时,结果也表明基于股市安排（如基于最紧密关系选取的股票）每两支证券指数收益序列在全球金融危机后升高,这暗示了较高不同时性（与金融危机的相关性较小）,然而,另一方面,基于最差关联性的证券指数,金融危机后收益序列降低,表明较高不同时性（与金融危机有相关性）。比较相关系数以及cross-SampEn,我们进一步发现cross-SampEn可更好地描述各个时间段之间的相互关系,从而提供一种选择性的并实用的方法来展示时间段之间的关系。结果进一步表明彼此关联较弱的市场依然存在,并且国与国之间受到危机的影响程度不同。

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The reversal of antineoplastic drug resistance in cancer cells by β-elemene

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癌症 2015年第11期34卷 488-495页

作者： Guan-Nan Zhang Charles R.Ashby jr. Yun-Kai Zhang Zhe-Sheng Chen Huiqin Guo Department of Pharmaceutical Sciences College of Pharmacy and Health Sciences St. John’s University Department of Thoracic Surgery Peking Union Medical College Hospital

Multidrug resistance(MDR), deined as the resistance of cancer cells to compounds with diverse structures and mechanisms of actions, signiicantly limits the eicacy of antitumor drugs. A major mechanism that mediates MDR in cancer is the overexpression of adenosine triphosphate(ATP)?binding cassette transporters. These transporters bind to their respective substrates and catalyze their elux from cancer cells, thereby lowering the intracellular concentra?tions of the substrates and thus attenuating or even abolishing their eicacy. In addition, cancer cells can become resistant to drugs via mechanisms that attenuate apoptosis and cell cycle arrest such as alterations in the p53, check point kinase, nuclear factor kappa B, and the p38 mitogen?activated protein kinase pathway. In this review, we discuss the mechanisms by which β?elemene, a compound extracted from Rhizoma zedoariae that has clinical antitumor eicacy, overcomes drug resistance in cancer.

关键词： Rhizoma zedoariae β?Elemene Multidrug resistance

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Estimating Trade Mis-invoicing from China:2000-2005

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China & World Economy 2008年第2期16卷 82-92页

作者： Edsel L.Beja jr. Deputy Director Ateneo Center for Economic Research and DevelopmentAteneo de Manila UniversityQuezon CityPhilippines

An examination of available data reveals large trade misinvoicing between China and its trade partners. The analysis finds a net trade misinvoicing of US$287.6bn between 2000 and 2005, while the full magnitude of unrecorded trade is estimated at US$1.4tn. China needs to establish more effective management of its international trade flows. At the same time, the international community needs to provide more effective governance mechanisms to address trade misinvoicing.

关键词： intemational trade flows policy challenges for China trade misinvoicing

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