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Multi-Step Clustering of Smart Meters Time Series:Application to Demand Flexibility Characterization of SMe Customers

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Computer Modeling in engineering & Sciences 2025年第1期142卷 869-907页

作者： Santiago bañales Raquel Dormido Natividad Duro Department of Computer Sciences and Automatic Control Universidad Nacional de Educación a Distancia(UNED)Madrid28040Spain Iberdrola Innovation Middle east Doha210177Qatar

Customer segmentation according to load-shape profiles using smart meter data is an increasingly important application to vital the planning and operation of energy systems and to enable citizens’participation in the energy *** study proposes an innovative multi-step clustering procedure to segment customers based on load-shape patterns at the daily and intra-daily time *** meter data is split between daily and hourly normalized time series to assess monthly,weekly,daily,and hourly seasonality patterns *** dimensionality reduction implicit in the splitting allows a direct approach to clustering raw daily energy time series *** intraday clustering procedure sequentially identifies representative hourly day-unit profiles for each customer and the entire *** the first time,a step function approach is applied to reduce time series *** attributes embedded in surveys are employed to build external clustering validation metrics using Cramer’s V correlation factors and to identify statistically significant determinants of load-shape in energy *** addition,a time series features engineering approach is used to extract 16 relevant demand flexibility indicators that characterize customers and corresponding clusters along four different axes:available energy(e),Temporal patterns(T),Consistency(C),and Variability(V).The methodology is implemented on a real-world electricity consumption dataset of 325 Small and Medium-sized enterprise(SMe)customers,identifying 4 daily and 6 hourly easy-to-interpret,well-defined *** application of the methodology includes selecting key parameters via grid search and a thorough comparison of clustering distances and methods to ensure the robustness of the *** research can test the scalability of the methodology to larger datasets from various customer segments(households and large commercial)and locations with different weather and socioeconomic conditio

关键词： electric load clustering load profiling smart meters machine learning data mining demand flexibility demand response

Cytochrome P450 2e1 RsaI/PstI and DraI Polymorphisms Are Risk Factors for Lung Cancer in Mongolian and Han Population in Inner Mongolia

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Chinese Journal of Cancer Research 2011年第2期23卷 107-111页

作者： Xiu-lan Su ba Bin Hong-wei Cui Mei-rong Ran Clinical Medical Center Affiliated Hospital Inner Mongolian Medical College Hohhot 010050 China Department of Internal Medicine Medical Emergency Center of Kangbashi New Direct Erdos City Inner Mongolia China

Objective： To explore the relationship between cytochrome P450 2e1 （CYP2e1） RsaI/PstI and DraI polymorphism and lung cancer susceptibility in Mongolian and Han population in Inner Mongolia of China. Methods： CYP2e1 RsaI/PstI and DraI polymorphisms were detected by polymerase chain reaction-restriction fragment length polymorphism in 64 lung cancer patients, 150 healthy Mongolian and 150 healthy Han individuals. The distribution of genotype and allele frequencies of CYP2e1 RsaI/PstI and DraI polymorphisms were studied. Results： The risk of lung cancer was increased in individuals with CYP2e1 （cl/cl） and CYP2e1 （DD） with OR values of 2.431 （95%CI=1.082-5.460） and 2.778 （95%CI=1.358-5.683） respectively （P0.05）. When CYP2e1 RsaI/PstI and DraI polymorphisms were combined, the risk of lung cancer was reduced in individuals with CYP2e1 （cl/c2＋c2/c2 and DD＋CC） with OR values of 0.233 （95%CI=0.088-0.615, P0.05）. In smokers, the susceptibility to lung cancer was higher in the individuals with CYP2e1 （c1/c1） and CYP2e1 （DD） than in the individuals with c2 and C allele （P0.05, OR=2.643 and 4.308 respectively）. There was no significant difference in distribution of CYP2e1 genotype frequency between healthy Mongolian, Han population and lung cancer patients, healthy controls in Inner Mongolia. Conclusion： CYP2e1 （c1/c1） and CYP2e1 （DD） are predisposing factors of lung cancer in population in Inner Mongolia. CYP2e1 （c2﹢C） co-mutation may decrease the risk of lung cancer. Smoking exerts synergetic effect with CYP2e1 （c1/c1） and CYP2e1 （DD） on the occurrence of lung cancer.

关键词： Cytochrome p450 2e1 Gene polymorphism Lung cancer Susceptivity

The effect of propagation delay on the dynamic evolution of the Bitcoin blockchain

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Digital Communications and Networks 2020年第2期6卷 157-166页

作者： Moustapha ba MODAL’X(Laboratoire de Modélisation aléatoire)of UniversitéParis Nanterre(Paris X) MODAL’X is the Mathematics and Computer Sciences laboratory of UniversitéParis Nanterre(Paris X)ministerial label EA 3454UFR SEGMIdépartement Mathématiques-Informatique200 avenue de la République92000NanterreFrance

This paper analyzes the selfish-mine strategy in the Bitcoin blockchain introduced in 2013 by *** and *** strategy could be used by a colluding pool of miners to earn more than their fair share of the mining revenue and in consequence to force other honest miners to join them to decrease the variance of their revenues and make their monthly revenues more *** is a very dangerous dynamic that could allow the rogue pool of miners to go toward a majority by accumulating powers of news adherents and control the entire *** that the propagation delay of information between any two miners in the network,which is not negligible and follows a normal distribution with mean proportional to the physical distance between the two miners,and a constant variance independent of others'delays,we prove that no guarantee can be given about the success or failure of the selfish-mine attack because of the variability of information propagation in the network.

关键词： Blockchain Bitcoin Mining Selfish-mine attack Propagation delay of information

Production and Mechanical Behaviour of Biomedical CoCrMo Alloy

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Chinese Physics Letters 2011年第12期28卷 215-218页

作者： O.Sahin A.Rıza Tuncdemir H.Ali Cetinkara H.Salih Guder e.Sahin Department of Physics Art and Science FacultyMicro/Nanomechanic Characterization LaboratoryMustafa Kemal UniversityHatayTurkey Department of Prosthetic Dentistry Dentistry FacultyMustafa Kemal UniversityHatayTurkey

Cobalt-based alloy(Co-30Cr-5.5Mo)is produced by the investment casting *** alloy complies with the ASTM F75 standard and is widely used in the manufacturing of orthopedic implants because of its high strength,good corrosion resistance and excellent biocompatibility ***,XRD and microhardness tests are used to examine the mechanical properties of the *** examined material exhibits the behaviour of indentation size effect(ISe).Our results reveal that Vickers and Knoop microhardness are dependent on indentation test *** traditional Meyer's law,the proportional specimen resistance(PSR)model and the Hays-Kendall model(HK)are used to analyze the load dependence of the *** a result,the Hays-Kendall model is found to be the most effective to determine the load-independent hardness HLI of CoCrMo alloy.

关键词： alloy resistance process

P-wave velocity prediction in porous medium with liquid-pocket patchy saturation

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Applied Mathematics and Mechanics(english edition) 2015年第11期36卷 1427-1440页

作者： Jiawei LIU Weitao SUN Jing ba Zhou Pei-Yuan Center for Applied Mathematics Tsinghua University Department of Computational Geophysics Xi'an Jiaotong University

It becomes increasingly clear that non-uniform distribution of immiscible fluids in porous rock is particularly relevant to seismic wave dispersion. White proposed a patchy saturation model in 1975, in which spherical gas pockets were located at the center of a liquid saturated cube. For an extremely light and compressible inner gas, the physical properties can be approximated by a vacuum with White＇s model. The model successfully analyzes the dispersion phenomena of a P-wave velocity in gas-water- saturated rocks. In the case of liquid pocket saturation, e.g., an oil-pocket surrounded by a water saturated host matrix, the light fluid-pocket assumption is doubtful, and few works have been reported in White＇s framework. In this work, Poisson＇s ratio, the bulk modulus, and the effective density of a dual-liquid saturated medium are formulated for the heterogeneous porous rocks containing liquid-pockets. The analysis of the difference between the newly derived bulk modulus and that of White＇s model shows that the effects of liquid-pocket saturation do not disappear unless the porosity approaches zero. The inner pocket fluid can no longer be ignored. The improvements of the P-wave velocity predictions are illustrated with two examples taken from experiments, i.e., the P-wave velocity in the sandstone saturated by oil and brine and the P-wave velocity for heavy oils and stones at different temperatures.

关键词： White's model porous medium P-wave dispersion liquid pocket

enhancing perianal disease management with integrated physical and psychological approaches

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World Journal of Clinical Cases 2025年第2期13卷 59-63页

作者： Uchenna e Okpete Haewon Byeon Department of Digital Anti-aging Healthcare(BK21) Inje UniversityGimhae 50834South Korea

This article provides a comprehensive analysis of the study by Hou et al,focusing on the complex interplay between psychological and physical factors in the postoperative recovery(POR)of patients with perianal *** study sheds light on how illness perception,anxiety,and depression significantly influence recovery *** et al developed a predictive model that demonstrated high accuracy in identifying patients at risk of poor *** article explores the critical role of pre-operative psychological assessment,highlighting the need for mental health support and personalized recovery plans in enhancing POR quality.A multidisciplinary approach,integrating mental health professionals with surgeons,anesthesiologists,and other specialists,is emphasized to ensure comprehensive care for *** study’s findings serve as a call to integrate psychological care into surgical practice to optimize outcomes for patients with perianal diseases.

关键词： Perianal disease Post-operative recovery Anxiety Depression Pain management emotional well-being Multidisciplinary approach

Brain-derived neurotrophic factor alterations and cognitive decline in schizophrenia:Implications for early intervention

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World Journal of Psychiatry 2025年第1期15卷 189-193页

作者： Uchenna e Okpete Haewon Byeon Department of Digital Anti-aging Healthcare(BK21) Inje UniversityGimhae 50834South Korea

This manuscript explores the recent study by Cui et al which assessed the interplay between inflammatory cytokines and brain-derived neurotrophic factor(BDNF)levels in first-episode schizophrenia *** study revealed that higher levels of interleukin-6 and tumor necrosis factor-αcorrelated with reduced BDNF levels and poorer cognitive *** is a severe psy-chiatric disorder impacting approximately 1%of the global population,charac-terized by positive symptoms(hallucinations and delusions),negative symptoms(diminished motivation and cognitive impairments)and disorganized thoughts and *** research highlights the role of BDNF as a potential biomarker for early diagnosis and therapeutic *** findings from Cui et al’s study suggest that targeting neuroinflammation and enhancing BDNF levels may improve cognitive *** treatment approaches involve a com-bination of pharmacological and non-pharmacological interventions tailored to individual patient ***,monitoring cognitive and neuroinflammatory markers is essential for improving patient outcomes and quality of ***-quently,this manuscript highlights the need for an integrated approach to schizo-phrenia management,considering both clinical symptoms and underlying neuro-biological changes.

关键词： Schizophrenia Cognitive impairment Neuroinflammatory markers Brain-derived neurotrophic factor Interleukin Personalized treatment

A Unified Trajectory Optimization Approach for Long-Term and Reactive Motion Planning of Legged Locomotion

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Journal of Bionic engineering 2023年第5期20卷 2108-2122页

作者： Yapeng Shi Bin Yu Kaixian ba Mantian Li School of Mechanical engineering Yanshan UniversityNo.438 West Hebei AvenueQinhuangdao066004HebeiPeople’s Republic of China State Key Laboratory of Robotics and System Harbin Institute of TechnologyHarbin150001People’s Republic of China

This paper proposes a unified trajectory optimization approach that simultaneously optimizes the trajectory of the center of mass and footholds for legged *** on a generic point-mass model,the approach is formulated as a nonlinear optimization problem,incorporating constraints such as robot kinematics,dynamics,ground reaction forces,obstacles,and target *** unified optimization approach can be applied to both long-term motion planning and the reactive online planning through the use of model predictive control,and it incorporates vector field guidance to converge to the long-term planned *** effectiveness of the approach is demonstrated through simulations and physical experiments,showing its ability to generate a variety of walking and jumping gaits,as well as transitions between them,and to perform reactive walking in obstructed environments.

关键词： Legged locomotion Motion planning Trajectory optimization Bionic robot

An end-to-end 3D seismic simulation of underground structures due to point dislocation source by using an FK-FeM hybrid approach

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Frontiers of Structural and Civil engineering 2022年第12期16卷 1515-1529页

作者： Zhenning ba Jisai FU Zhihui ZHU Hao ZHONG State Key Laboratory of Hydraulic engineering Simulation and Safety Tianjin UniversityTianjin 300072China School of Civil engineering Tianjin UniversityTianjin 300350China National engineering Research Center of High Speed Railway Construction Technology Central South UniversityChangsha 410075China School of Civil engineering Central South UniversityChangsha 410075China

based on the domain reduction idea and artificial boundary substructure method,this paper proposes an FK-FeM hybrid approach by integrating the advantages of FK and FeM(i.e.,FK can efficiently generate high-frequency three translational motion,while FeM has rich elements types and constitutive models).An advantage of this approach is that it realizes the entire process simulation from point dislocation source to underground *** with the plane wave field input method,the FK-FeM hybrid approach can reflect the spatial variability of seismic motion and the influence of source and propagation *** approach can provide an effective solution for seismic analysis of underground structures under scenario of earthquake in regions where strong earthquakes may occur but are not recorded,especially when active faults,crustal,and soil parameters are *** Daikai subway station as an example,the seismic response of the underground structure is simulated after verifying the correctness of the approach and the effects of crustal velocity structure and source parameters on the seismic response of Daikai station are *** this example,the influence of velocity structure on the maximum interlayer displacement angle of underground structure is 96.5%and the change of source parameters can lead to the change of structural failure direction.

关键词： source-to-structure simulation FK-FeM hybrid approach underground structures point dislocation source