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Ameliorative effect of vitamin e on aflatoxin-induced lipid peroxidation in the testis of mice

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Asian Journal of Andrology 2001年第3期3卷 217-221页

作者： R.J.Verma anita Nair Department of Zoology University School of Sciences Guarat University Ahmedabad 380009 IndiaDepartment of Zoology University School of Sciences Guarat University Ahmedabad 380009 India

Aim: To evaluate the ameliorative effect of vitamin e on aflatoxin-induced lipid peroxidation in the testis. Meth-ods: Adult male albino mice were orally administered 25 or 50 μg of aflatoxin in 0.2 mL olive oil per d for 45 *** testis was isolated, blotted free of blood and processed for biochemical analysis. Results: There was a dose-de-pendent significantly higher lipid peroxidation in the testis of aflatoxin treated mice than in the controls. The levels ofnon-enzymatic antioxidants such as glutathione, total and reduced ascorbic acid, as well as the activities of enzymaticantioxidants, such as superoxide dismutase, glutathione peroxidase and catalase were significantly lower in the testis ofaflatoxin treated mice. Vitamin e (2 mg/d per animal; orally) pretreatment significantly ameliorates the aflatoxin-in-duced lipid peroxidation which could be due to higher enzymatic and non-enzymatic antioxidants in the testis of mice ascompared with those given aflatoxin alone. Conclusion: Vitamin e pretreatment significantly ameliorates aflatoxin-induced lipid peroxidation in the testis of mice. (Asian J Androl 2001 Sep; 3: 217 - 221)

关键词： aflatoxins vitamin e testis lipid peroxidation

Vitamin e ameliorates aflatoxin-induced biochemical changes in the testis of mice

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Asian Journal of Andrology 2001年第4期3卷 305-309页

作者： R.J.Verma anita Nair Department of Zoology University School of Sciences Gujarat University Ahmedabad-380 009 IndiaDepartment of Zoology University School of Sciences Gujarat University Ahmedabad-380 009 India

Aim: To assess the effect of aflatoxin on biochemical changes in the testis of mice and the possibility of ameliorationby vitamin e treatment. Methods: Adult male albino mice were orally administered with 25 or 50μg of aflatoxin/animal/day (750 or 1500 μg/kg body weight) for 45 days. The testis was isolated and processed for biochemical anal-ysis. Results; There was a significant, dose-dependent reduction in DNA, RNA, protein, sialic acid contents andthe activities of succinic dehydrogenase, adenosine triphosphatase and alkaline phosphatase in the testis of aflatoxin-treated mice as compared to the vehicle control. However, the acid phosphatase activity was significantly increased inthe aflatoxin-treated mice. Vitamin e (2 mg/animal/day) treatment significantly ameliorated the aflatoxin-inducedchanges, except the acid and alkaline phosphatase activities in the high dose group. Conclusion; Vitamin e treat-ment ameliorates the aflatoxin-induced changes in the testis of mice. (Asian J Androl 2001 Dec; 3: 305 - 309)

关键词： aflatoxin vitamin e testis biochemical changes

economic Development through Medicinal and Aromatic Plants(MAPs) Cultivation in Hindu Kush Himalaya Mountains of District Swat, Pakistan

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Journal of Mountain Science 2015年第5期12卷 1292-1301页

作者： Hassan SHeR mary e. BARKWORTH Center for Plant Sciences and Biodiversity University of Swat Intermountain Herbarium Department of Biology Utah State University

Poverty is pervasive in the Swat Valley in northwestern Pakistan, and most people survive by farming small landholdings. However, many supplement their meager subsistence earnings by collecting and selling plant material for use in herbal medicine. This material is wild-harvested, but collectors seem not to fully appreciate the potential value of the plant material they collect nor the longterm impact their collection has on local plant populations. A model project supported by the International Food Policy Research Institute(IFPRI)persuaded small-scale farmers in four different villages to use some of their land for cultivating traditionally wild-harvested species of medicinal and aromatic plants(MAPs) with high market value. The farmers were provided seeds or rhizomes of five MAPs and asked to monitor their germination and growth on 25 m2 plots during a 12 month period. At the end of the study, growth and yield data from the four localities were compared and economic analyses conducted to determine the profitability of the species based on yields, prevailing market prices, and costs of production. Five of the cultivated species were subsequently marketed and their value evaluated:Sesamum indicum, Linum usitatissimum, Ocimum basilicum, Nigella sativa and Viola pilosa. The MAPs V. pilosa and O. basilicum were the most profitable,whereas Nigella sativa was the least profitable because of its low germination rate. The net income from all but Nigella was higher than that would have been earned by planting the same area with the predominant cereals or tomatoes. In addition to demonstrating the feasibility and financial benefits of cultivating MAPs as a cash crop, this model study identified a number of additional steps that would increase the benefits of MAPs cultivation in this area.A combination of specialized education, market infrastructure development and a small loans program would enable farmers to increase their agricultural income without damaging the area's pl

关键词： Biological diversity Medicinal plant Aromatic plant Agriculture productivity Traditionalcrops economic analysis Himalaya Mountains

SPDeF： a molecular switch for e-cadherin expression that promotes prostate cancer metastasis

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Asian Journal of Andrology 2013年第5期15卷 584-585页

作者： mary Osisami evan T Keller Department of Urology University of Michigan AnnArbor M148105 USA

In order to design effective therapies for prostate cancer, a clear understanding of mechanisms that contribute to various components of prostate cancer progression is necessary. Study of metastasis suppressor genes, i.e., genes that can inhibit metastasis, is an important field of study that can lead to identification of therapeutic targets to diminish metastasis.

关键词： SPDeF a molecular switch metastasis

Superinfection of hepatitis e Virus as a cause of decompensation in liver cirrhosis due to hepatitis B virus

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Asian Pacific Journal of Tropical Medicine 2009年第2期2卷 54-57页

作者： Manisha Jain anita Chakravarti P Kar Mbbs Md Department of Microbiology Maulana Azad Medical College Department of Medicine Lok Nayak and Associated HospitalsNew Delhi-110019India

Objevtive:Super infection with hepatitis A virus(HAV ) and hepatitis e virus(HeV ) in the presence of underlying hepatocellular injury can cause severe *** endemic areas such as India,however most patients already have been exposed to HAV but could still be susceptible to HeV *** our study we determined the seroprevalence of anti-HAV IgM and anti-HeV IgM to assess the incidence of superinfection with these viruses in cirrhotic patients with the goal of defining the need for protection against these viruses and further correlate the presence of these viruses with the clinical ***:We studied 53 patients of cirrhosis as a result of Hepatitis B *** causes of decompensation were ruled out before their inclusion in the study *** sample from these patients was tested for HBsAg,anti HBc IgG,anti HeV IgM and anti HAV IgG and IgM by commercially available eLISA *** function test was done on all the patients and correlated with various serological ***:anti HBc IgG was present in all the cases of cirrhosis. Hepatitis B surface antigen was present in 20 out of 53 cases of *** of the patients demonstrated anti-HAV IgM,however one patient had anti-HeV ***:Superinfection with HAV in adult patient is uncommon in *** of acute HeV infection in decompensated cirrhosis is low in the present study but presence of HeV superinfection in one patient corroborates the apprehension of liver function deterioration following superinfection with HeV virus.

关键词： HeV HAV Superinfection Liver cirrhosis

Innovative and sustainable approach for phytoremediation of mine tailings:a review

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Waste Disposal and Sustainable energy 2019年第3期1卷 169-176页

作者： anita Punia Department of Civil engineering Indian Institute of TechnologyGuwahatiIndia

A review is designed to innovate a sustainable solution for the treatment of mine tailings using bioremediation and *** emphasizes on achieving the geochemical stability of tailings through the establishment of microbes or *** highlights the gaps in achieving the geochemical stability of *** of nutrients and low pH discourage the survival of microorganisms and the growth of plants on *** of tailings with agricultural waste(wheat and mustard stalks)would nourish tailings which promote the growth of microorganism and *** of agricultural waste in remediation process is *** role of microorganisms such as cyanobacteria,fungi,and algae are well known for mineralogical *** converts unavailable fraction of nutrient into available form and important initiative to drive tailings towards natural *** would support the growth of plants on tailings to achieve successful *** generation from tailings through high lipid and protein producing plants is important for sustainable *** will reduce the environmental impact caused by mine *** phytoremediation,use of biofuel producing plants,i.e.,Jatropha curcus and Brassica juncea,is recommended.

关键词： Mine tailings Mineral transformation Geochemical stability Phytoremediation

Antimicrobial ability and growth promoting effects of feed supplemented with probiotic bacterium isolated from gut microflora of Cirrhinus mrigala

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Journal of Integrative Agriculture 2015年第3期14卷 583-592页

作者： anita Bhatnagar Ritu Lamba Department of Zoology Kurukshetra University

The present studies were conducted to isolate, select, identify and characterize gut bacteria as antimicrobial and growth promoting agent for the feed of economically important fish Cirrhinus mrigala. Intestinal microflora were isolated, counted, and identified, and their in vitro antibacterial properties were determined. The results have revealed that occurrence of Gram-negative rods was around 75% and of Gram-positive rods was 25%. Among the isolates Gram-positive were maintained in nutrient agar slants at 4℃. Of these, eight strains were replica-plated on agar seeded with Aeromonas hydrophila and only one strain CM2（C. mrigala 2） exhibited antibacterial properties in vitro showing inhibition against fish pathogen by well diffusion assay. This isolated strain was identified as Bacillus cereus. This bacterium was mass cultured and incorporated in the pelleted diet（40% protein and 18 k J g^–1 gross energy） of C. mrigala to investigate its effect on growth performance, digestibility, nutrient retention and activities of digestive enzymes. The results of feeding trial revealed significantly（P〈0.05） high growth performance in terms of specific growth rate, growth percent gain in body weight（BD）（272.4±1.5）%, high apparent protein digestibility（（79.9±0.30）%） and low food conversion ratio in the group of fishes fed on diet containing B. cereus in comparison to the fishes fed on diet without probiotics. The carcass composition also revealed high accumulation of proteins（（15.28±0.15） g 100 g^–1） in fishes fed on diet containing probiotics. Intestinal enzyme activities of protease, amylase and cellulase were also significantly（P〈0.05） high in the group of fishes fed on diet supplemented with probiotics indicating the extracellular enzyme production by B. cereus. These results indicate that probiotics stimulate the digestion through the supply of digestive enzyme and certain essential nutrients to animals. Also significantly（P〈0.05） low excretion of metabolites, i.e., ammonia

关键词： Aeromonas Bacillus cereus digestive enzymes growth performance Cirrhinus mrigala probiotics

Playing Well on the Data FAIRground:Initiatives and Infrastructure in Research Data Management

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Data Intelligence 2019年第4期1卷 350-367页

作者： Danielle Descoteaux Chiara Farinelli Marina Soares e Silva anita de Waard elsevier Inc50 Hampshire StCambridgeMA 02139USA elsevier B.V.Radarweg 292043NX AmsterdamThe Netherlands

Over the past five years,elsevier has focused on implementing FAIR and best practices in data management,from data preservation through *** this paper we describe a series of efforts undertaken in this time to support proper data management *** particular,we discuss our journal data policies and their implementation,the current status and future goals for the research data management platform Mendeley Data,and clear and persistent linkages to individual data sets stored on external data repositories from corresponding published papers through partnership with *** analysis of our data policies implementation confirms significant disparities at the subject level regarding data sharing practices,with most uptake within disciplines of Physical *** directions at elsevier include implementing better discoverability of linked data within an article and incorporating research data usage metrics.

关键词： Open data Data sharing Data citation Open research

A Standard of excellence

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中国翻译 1995年第3期 61-62页

作者： mary e. Potter

My 14-year-old son, John, and I spotted thecoat simultaneously. It was hanging on a rack ata secondhand clothing store in Northampton,Mass., crammed in with shoddy trench coats andan assortment of sad, woollen overcoats—a roseamong thorns. While the other coats drooped, this onelooked as if it were holding itself up. The thick,black wool of the double-breasted chesterfieldwas soft and unworn, as though it had been pre-served in mothballs for years in dear old

关键词：盖茨比大衣普通名词英国历史美国小说生产厂家曼哈顿纽约市外交家再生