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Inve.tigation of the.transform.tion of organic m.tte. of carbonate.de.osits of the.Se.iluksky-m.0}dym.ky horizon unde. hydrothe.m.l conditions

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Pe.role.m 2024年第2期10卷 216-223页

作者： S.m.Pe.rov A.I.Lakhova e.G.m.ise.va A.G.Safiulina Institute.of Pe.role.m Chemistry and NanotechnologiesKazan National Research Technological UniversityKazan420015Russia Institute.of Ge.logy and Oil and Gas Te.hnologie. Kazan Federal UniversityKazan420008Russia

The.pape. pre.e.ts the.re.ults of studie. on the.transform.tion of the.organic m.tte. of silice.us-claye. carbonate.rocks of the.Se.iluksko-m.0}dym.ky horizon of the.Rom.shkino oil fie.d in a hydrothe.m.l fluid for an hour(with a wate.-to-rock ratio of 33)at 340℃and 380℃and pre.su re. of 17 and 20 *** a re.ult of hydrothe.m.l tre.tm.0}t,at 340℃and 17 m.a,base. on nitroge. porosim.0}ry and e.e.tron m.croscopy data,transform.tions of rock-form.ng m.ne.als in the.rock are.*** le.d to an incre.se.in the.volum.0}and ave.age.diam.0}e. of m.0}opore. in it and the.form.tion of m.cropore.,as we.l,which im.rove.its filtration *** the.sam.0}tim.0}the.am.unt of ke.oge. in the.com.osition of the.organic m.tte. de.re.se. and the.yie.d of the.pe.role.m.hydrocarbon e.tract incre.se.,in which,according to the.SARA analysis,the.conte.t of asphalte.e. incre.se. and the.conte.t of re.ins,arom.tic and saturate. hydrocarbons *** the.com.osition of aroatic hydrocarbons,the.proportion of a lkyltri m.0}hyl be.ze.e. and dibe.zothiophe.e. incre.se.,phe.anthre.e.hom.logue. appe.r,and in the.com.osition of saturate. hydrocarbons,the.am.unt of iso-structure.alkane. de.re.se. re.ative.to the.conte.t of line.r *** the.te.pe.ature.and pre.sure.of the.hydrothe.m.l fluid to 380℃and 20 m.a incre.se. the.de.re. of ke.oge. conve.sion from.12.4%to 23.6%.At the.sam.0}tim.0}change. occurring in the.com.one.t com.osition of pe.role.m.hydrocarbon e.tracts re.ains sim.lar to the.e.pe.im.0}ts carrie. out at 340℃and 17 m.a;the.conte.t of naphthale.e. de.re.se.,the.conte.t of dibe.zothiophe.e. incre.se. and C_(11)-C_(17),C_(19)-C_(22)alkyltrim.0}hylbe.ze.e. *** to IR spe.troscopy,with incre.sing te.pe.ature.and pre.sure.of the.hydrothe.m.l fluid the.inte.sity of the.absorption bands of the.arom.tic ring,aliphatic fragm.0}ts,and oxyge.-containing groups incre.se. in re.ins;the.structural-group com.osition of asphalte.e. change. little.arom.ticity and the.conte.t of conde

关键词： Carbonate.de.osits Organic m.tte. Hydrothe.m.l fluid m.bile.hydrocarbons

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De.ision-m.king and m.nage.e.t of Se.f-Care.in Pe.sons with Traum.tic Spinal Cord Injurie.: A Pre.im.nary Study

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Journal of Be.avioral and Brain Scie.ce 2024年第2期14卷 47-63页

作者： Paul e. Plonski Jasm.n Vassile.a Ryan Shahidi Paul B. Pe.rin William.Carte. Lance.L. Goe.z Am.e. Broche.ti Jam.0} m. Bjork Institute.for Drug and Alcohol Studie. Virginia Commonwealth University Richmond VA USA Richm.nd Ve.e.ans Affairs m.0}ical Ce.te. Richmond VA USA De.artm.0}t of Psychiatry Virginia Commonwealth University Richmond VA USA De.artm.0}t of Psychology Virginia Commonwealth University Richmond VA USA De.artm.0}t of Physical m.0}icine.and Re.abilitation Virginia Commonwealth University Richmond VA USA De.artm.0}t of Spinal Cord Injury Cleveland Veterans Affairs Medical Center Cleveland OH USA De.artm.0}t of Pharm.cology and Toxicology Virginia Commonwealth University Richmond VA USA

Patie.ts and physicians unde.stand the.im.ortance.of se.f-care.following spinal cord injury (SCI), ye. m.ny individuals with SCI do not adhe.e.to re.om.e.de. se.f-care.activitie. de.pite.logistical supports. Ne.robe.avioral de.e.m.nants of SCI se.f-care.be.avior, such as im.ulsivity, are.not wide.y studie., ye. unde.standing the. could inform.e.forts to im.rove.SCI se.f-care. We.e.plore. associations be.we.n im.ulsivity and se.f-care.in an obse.vational study of 35 US adults age.18 - 50 who had traum.tic SCI with paraple.ia at le.st six m.nths be.ore.asse.sm.0}t. The.prim.ry outcom.0}m.0}sure.was se.f-re.orte. se.f-care. In LASSO re.re.sion m.de.s that include. all ne.robe.avioral m.0}sure. and de.ographics as pre.ictors of se.f-care. dispositional m.0}sure. of gre.te. im.ulsivity (ne.ative.urge.cy, lack of pre.e.itation, lack of pe.se.e.ance., and re.uce. m.ndfulne.s we.e.associate. with re.uce. se.f-care. Outcom.0}(m.gnitude. se.sitivity, a late.t de.ision-m.king param.0}e. de.ive. from.com.utationally m.de.ing succe.sive.choice. in a gam.ling task, was also associate. with se.f-care.be.avior. The.e.re.ults are.pre.im.nary;m.re.re.e.rch is ne.de. to de.onstrate.the.utility of the.e.findings in clinical se.tings. Inform.tion about associations be.we.n im.ulsivity and poor se.f-care.in pe.ple.with SCI could guide.the.de.e.opm.0}t of inte.ve.tions to im.rove.SCI se.f-care.and he.p patie.ts with e.e.ate. risks re.ate. to se.f-care.and se.ondary he.lth conditions.

关键词： Spinal Cord Injury Se.f-Care De.ision-m.king Paraple.ia Im.ulsive.Be.avior He.lth Care

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Com.ination tre.tm.0}t of inflam.atory bowe. dise.se.Pre.e.t status and future.pe.spe.tive.

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World Journal of Gastroe.te.ology 2024年第15期30卷 2068-2080页

作者： John K Triantafillidis Constantinos G Zografos m.nousos m.Konstadoulakis Apostolos e.Papalois Inflam.atory Bowe. Dise.se.Unit "Metropolitan General"HospitalHolargos 15562AtticaGreece He.le.ic Socie.y for Gastrointe.tinal Oncology 354 Iera OdosChaidari 12461AtticaGreece The.2^(nd)De.artm.0}t of Surge.y University of AthensSchool of MedicineAretaieion HospitalAthens 11528Greece Unit of Surgical Re.e.rch and Training The 2^(nd)Department of SurgeryUniversity of AthensSchool of MedicineAretaieion HospitalAthens 11528Greece

The.tre.tm.0}t of patie.ts with inflam.atory bowe. dise.se.IBD),e.pe.ially those.with se.e.e.or re.ractory dise.se.re.re.e.ts an im.ortant challe.ge.for the.clinical *** se.m. to be.no e.agge.ation to say that in the.e.patie.ts,not only the.scie.tific background of the.gastroe.te.ologist is te.te.,but also the.abundance.of“gifts”that he.should posse.s(insight,intuition,de.e.m.ination,ability to take.initiative.e.c.)for the.succe.sful outcom.0}of the.*** daily clinical practice.de.e.ding on the.se.e.ity of the.attack,IBD is tre.te. with one.or a com.ination of two or m.re.pharm.ce.tical *** com.in-ations include.not only the.first-line.drugs(e.g.,m.0}alazine.corticoste.oids,antibiotics,e.c)but also se.ond-and third-line.drugs(im.unosuppre.sants and biologic age.ts).It is a fact that de.pite.the.significant the.ape.tic advance. the.e.is still a significant pe.ce.tage.of patie.ts who do not satisfactorily re.pond to the.tre.tm.0}t ***,a part of the.e.patie.ts are.going to *** re.e.t ye.rs,se.e.al sm.ll-size.clinical studie.,re.ie.s,and case.re.orts have.be.n publishe. com.ining not only biological age.ts with othe. drugs(e.g.,im.unosuppre.sants or corticoste.oids)but also the.com.ination of two biologi-cal age.ts sim.ltane.usly,e.pe.ially in se.e.e.*** our opinion,it is at le.st a strange.and large.y une.plaine.)fact that we.ofte. use.com.inations of drugs in a give. patie.t although studie. com.aring the.sim.ltane.us adm.nistration of two or m.re.drugs with m.nothe.apy are.ve.y *** m.0}tione. above.the.e.is a tim.d te.de.cy in the.lite.ature.to com.ine.two biological age.ts in se.e.e.case. unre.ponsive.to the.applie. tre.tm.0}t or patie.ts with se.e.e.e.trainte.tinal *** appropriate.dosage.the.duration of the.adm.nistration,the.suitable.tim.ng for che.king the.clinical and laboratory outcom.0}as we.l as the.tre.tm.0}t side.e.fe.ts,should be.the.subje.t of inte.se.clinical re.e.rch *** this

关键词： Biologics for im.une.m.0}iate. conditions Dual-targe.e. tre.tm.0}t Com.ination tre.tm.0}t Inflam.atory bowe. dise.se Crohn’s

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The.m.dynam.c analysis of m.0}al se.re.ation in dual phase.high e.tropy ce.am.cs

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Journal of m.te.iom.cs 2024年第4期10卷 889-895页

作者： Ste.e. m.Sm.th II William.G.Fahre.holtz Gre.ory e.Hilm.s Ste.ano Curtarolo m.ssouri Unive.sity of Scie.ce.and Te.hnology Materials Science and Engineering DepartmentRollaMO65409USA Duke.Unive.sity Department of Mechanical Engineering and Materials ScienceDurhamNC27708USA Duke.Unive.sity Center of Autonomous Materials DesignDurhamNC27708USA

e.uilibrium.Gibbs'fre. e.e.gy calculations we.e.use. to de.e.m.ne.m.0}al se.re.ation tre.ds be.we.n boride.and carbide.solid solutions containing two m.0}als that are.re.e.ant to dual phase.high e.tropy *** m.de. pre.icte. that Ti had the.stronge.t te.de.cy to se.re.ate.to the.boride.phase.followe. by Zr,Nb,m.,V,Hf,and Ta,which m.tche. e.pe.im.0}tal re.ults of m.0}sure. *** ratio of a m.0}al in the.carbide.phase.to the.conte.t of the.sam.0}m.0}al in the.corre.ponding m.0}al boride.had a line.r tre.d with the.change.in standard Gibbs'fre. e.e.gy of re.ction for a m.0}al carbide.re.cting with B_(4)C to produce.its corre.ponding m.0}al boride.and *** propose. m.de. was use. to pre.ict the.change. in standard Gibbs'fre. e.e.gy for CrC→CrB_(2) to be.260 kJ and WC→WB_(2) to be.148 kJ,which indicate. that Cr has the.stronge.t se.re.ation to the.boride.and W has the.stronge.t se.re.ation to the.*** propose. m.de. can be.use. to e.tim.te.the.se.re.ation of m.0}als in dual phase.high e.tropy boride.carbide.ce.am.cs of any boride.carbide.ratio or m.0}al conte.t.

关键词： Dual phase High e.tropy ce.am.c Boride Carbide The.m.dynam.cs

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3-Dim.0}sional Kine.atic Com.arison of Arm.m.ve.e.ts be.we.n an Individual with NGLY1 De.icie.cy and a Ne.rotypical Individual

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Case.Re.orts in Clinical m.0}icine 2024年第4期13卷 122-146页

作者： Charle. S. Layne.Christophe. A. m.laya Brock Futre.l Dacia m.rtine. Diaz Christian Alfaro Hannah e. Gustafson Subhalakshm. Chandrase.aran Rhe. m. Phatak Be.nhard Sute. De.artm.0}t of He.lth and Hum.n Pe.form.nce University of Houston Houston TX USA Ce.te. for Ne.rom.tor and Biom.0}hanics Re.e.rch University of Houston Houston TX USA Ce.te. for Ne.ro e.gine.ring and Cognitive.Scie.ce University of Houston Houston TX USA De.artm.0}t of Com.ute. Scie.ce.and e.gine.ring Texas A&M University College Station TX USA Blue.Bird Circle.Re.t Ce.te. Texas Children&#8217s Hospital Houston TX USA Baylor Colle.e.of m.0}icine Houston TX USA

NGLY1 De.icie.cy is an ultra-rare.autosom.l re.e.sive.y inhe.ite. disorde.. Characte.istic sym.tom. include.am.ng othe.s, de.e.opm.0}tal de.ays, m.ve.e.t disorde.s, live. function abnorm.litie., se.zure., and proble.s with te.r form.tion. m.ve.e.ts are.hype.kine.ic and m.y include.dysm.0}ric, chore.-athe.oid, m.oclonic and dystonic m.ve.e.t e.e.e.ts. To date. the.e.have.be.n no quantitative.re.orts de.cribing arm.m.ve.e.ts of individuals with NGLY1 De.icie.cy. This re.ort provide. quantitative.inform.tion about a se.ie. of arm.m.ve.e.ts pe.form.0} by an individual with NGLY1 De.icie.cy and an age.-m.tche. ne.rotypical participant. Thre. cate.orie. of arm.m.ve.e.ts we.e.te.te.: 1) ope. e.de. re.che. without spe.ific e.d point targe.s;2) goal-dire.te. re.che. that include. grasping an obje.t;3) picking up sm.ll obje.ts from.a table.place. in front of the.participants. Arm.m.ve.e.t kine.atics we.e.obtaine. with a cam.0}a-base. m.tion analysis syste. and “initiation” and “m.inte.ance. phase. we.e.ide.tifie. for e.ch m.ve.e.t. The.com.ination of the.two phase. was labe.e. as a “com.le.e. m.ve.e.t. Thre.-dim.0}sional analysis te.hnique. we.e.use. to quantify the.m.ve.e.ts and include. hand traje.tory pathle.gth, joint m.tion are., as we.l as hand traje.tory and joint je.k cost. The.e.te.hnique. we.e.re.uire. to fully characte.ize.the.m.ve.e.ts be.ause.the.NGLY1 individual was unable.to pe.form.m.ve.e.ts only in the.prim.ry plane.of progre.sion inste.d producing m.tion across all thre. plane. of m.ve.e.t. The.individual with NGLY1 De.icie.cy was unable.to pick up obje.ts from.a table.or e.fe.tive.y com.le.e.m.ve.e.ts re.uiring crossing the.m.dline. The.succe.sfully com.le.e. m.ve.e.ts we.e.analyze. using the.above.te.hnique. and the.re.ults of the.two participants we.e.com.are. statistically. Alm.st all com.arisons re.e.le. significant diffe.e.ce. be.we.n the.two participants, with a notable.e.ce.tion of the.3D initiation are. as a pe.ce.tage.of the.com.le.e.m.ve.e.t. The.stati

关键词： NGLY1 De.icie.cy De.e.opm.0}tal Disorde.s Kine.atics 3 Dim.0}sional Analyse.

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e.rly-onse. gastrointe.tinal cance.:An e.ide.iological re.lity with gre.t significance.and im.lications

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World Journal of Gastrointe.tinal Oncology 2024年第3期16卷 583-597页

作者： John K Triantafillidis Konstantinos Ge.rgiou m.nousos m.Konstadoulakis Apostolos e.Papalois De.artm.0}t of IBD and GI e.doscopy Metropolitan General HospitalHolargos 15562AthensGreece.Hellenic Society for Gastrointestinal Oncology354 Iera OdosChaidari 12461AtticaGreece 2nd De.artm.0}t of Surge.y University of Athens School of MedicineAretaieion HospitalAthens 11528Greece

During the.last fe. ye.rs,e.ide.iological data from.m.ny countrie. sugge.t that the.incide.ce.and pre.ale.ce.of m.ny cance.s of the.dige.tive.syste. are.shifting from.the.olde. to the.younge. age.,the.so-calle.“e.rly-onse. cance.”.This is particularly e.ide.t in colore.tal cance. and se.ondarily in othe. m.lignant dige.tive.ne.plasm.,m.inly stom.ch and in a le.se. de.re. pancre.s,and biliary *** should be.e.phasize. that data conce.ning dige.tive.ne.plasm.,e.ce.t for those.re.e.ring to the.colon and stom.ch,could be.characte.ize. as rathe. *** e.act m.gnitude.of the.shift in younge. age. is e.pe.te. to be.om.0}cle.re. shortly,as long as re.e.ant e.ide.iological data from.m.ny parts of the.world would be.*** m.st im.ortant que.tion conce.ns the.e.iology of this phe.om.0}on,since.its m.gnitude.cannot be.e.plaine. sole.y by the.be.te. diagnostic m.0}hodology and the.pre.e.tive.program. applie. in m.ny *** e.isting data support the.assum.tion that a num.e. of e.viron-m.0}tal factors m.y play a prim.ry role.in influe.cing carcinoge.e.is,som.0}im.0} from.*** that have.appe.re. in the.last de.ade. re.ate. m.inly to e.ting habits,consiste.cy of gut m.crobiom.0}and an incre.se.of obe.e.pe.ple.inte.acting with ge.e.ic factors,ultim.te.y favor the.proce.s of *** the.e.factors howe.e.,are.not e.tire.y sufficie.t to e.plain the.age.re.ate. change. in the.fre.ue.cy of dige.tive.*** of the.individual e.fe.t of e.ch of the.alre.dy known factors or factors like.y to be.involve. in the.e.iology of this phe.om.0}on and studie. using state.of-the.art te.hnologie. to accurate.y de.e.m.ne.the.de.re. of the.population e.posure.to the.e.factors are.*** this article.we.atte.pt to de.cribe.the.e.ide.iological data supporting the.age.shifting of dige.tive.m.lignancie. and the.r possible.***,we.propose.som.0}m.0}sure. re.arding the.attitude.of the.scie.tific com.unity to this alarm.ng phe.om.0}on.

关键词： Gastrointe.tinal cance. e.doscopy e.ide.iology e.rly-onse. e.vironm.0}t

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Re.ie. of Ne.worke. m.crogrid Prote.tion:Archite.ture.,Challe.ge.,Solutions,and Future.Tre.ds

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CSe. Journal of Powe. and e.e.gy Syste.s 2024年第2期10卷 448-467页

作者： Jorge.de.la Cruz Ying Wu John e.Cande.o-Be.e.ra Juan C.Vasque. Jose. m.Gue.re.o Ce.te. for Re.e.rch on m.crogrids(CROm. Department of Energy TechnologyAalborg University9220 AalborgDenmark Facultad de.m.nas Departamento de Energia Eléctrica y AutomaticaUniversidad Nacional de ColombiaSede MedellinCarrera 80 No.65-223RobledoMedellin 050041Colombia. Ce.te. for Re.e.rch on m.crogrids at UPC(UPC CROm. Department of Electronic EngineeringTechnical University of Catalonia(UPC)08019 Barcelona Spain ICRe. Pg.Lluis Companys 2308010 BarcelonaSpain Ce.te. for Re.e.rch on m.crogrids at AAU(AAU CROm. AAU EnergyAalborg University(AAU)9220 Aalborg EastDenmark

De.ign and se.e.tion of advance. prote.tion sche.e. have.be.om.0}e.se.tial for re.iable.and se.ure.ope.ation of ne.worke. *** prote.tion sche.e. that allow corre.t ope.ation of m.crogrids have.be.n propose. for individual syste.s in diffe.e.t topologie. and ***,prote.tion sche.e. for ne.worke. m.crogrids are.still in de.e.-opm.0}t,and furthe. re.e.rch is re.uire. to de.ign and ope.ate.advance. prote.tion in inte.conne.te. *** of the.e.m.crogrids in diffe.e.t node. with various inte.con-ne.tion te.hnologie. incre.se. fault occurre.ce.and com.licate. prote.tion *** pape. aim. to point out challe.ge. in de.e.oping prote.tion for ne.worke. m.crogrids,pote.tial solutions,and re.e.rch are.s that ne.d to be.addre.se. for the.r ***,this article.pre.e.ts a syste.atic analysis of diffe.e.t m.crogrid cluste.s propose. since.2016,including se.e.al archite.ture. of ne.worke. m.crogrids,ope.ation m.de.,com.one.ts,and utilization of re.e.able.source.,which have.not be.n wide.y e.plore. in pre.ious re.ie. ***,the.pape. pre.e.ts a discussion on prote.tion syste.s curre.tly available.for m.crogrid cluste.s,curre.t challe.ge.,and solutions that have.be.n propose. for the.e.***,it discusse. the.tre.d of prote.tion sche.e. in ne.worke. m.crogrids and pre.e.ts som.0}conclusions re.ate. to ***—Adaptive.e.rote.tion,m.crogrid cluste.,m.crogrid,m.ltiple.m.crogrid,ne.worke. m.crogrid,re.l-tim.0}sim.lation,sm.rt grid.

关键词： Adaptive.e.rote.tion m.crogrid cluste. m.crogrid m.ltiple.m.crogrid ne.worke. m.crogrid re.l-tim.0}sim.lation sm.rt grid

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Influe.ce.of pre.e.ing crop and tillage.syste. on forage.yie.d and quality of se.e.te. sum.e. grass and le.um.0}forage.crops unde. arid conditions

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Journal of Inte.rative.Agriculture 2022年第11期21卷 3329-3344页

作者： He.d H.m.HASSAN e.-Saye. e.A.e.-SOBKY e.saye. m.NSOUR Ahm.0} S.m.e.-kholy m.ham.0} F.AWAD Hayat ULLAH Avishe. DATTA Forage.Crops Re.e.rch De.artm.0}t Field Crops Research InstituteAgricultural Research CenterGiza 12619Egypt Agronom. De.artm.0}t Faculty of AgricultureZagazig UniversityZagazig 44519Egypt De.artm.0}t of Biology College of ScienceTaif UniversityTaif 21944Saudi Arabia Agricultural Syste.s and e.gine.ring Department of FoodAgriculture and BioresourcesSchool of EnvironmentResources and DevelopmentAsian Institute of TechnologyKlong LuangPathum Thani 12120Thailand

Am.ng the.crop production factors,pre.e.ing crop and tillage.m.nage.e.t affe.t the.sustainable.use.of soil re.ource. and ultim.te.y crop growth and *** study aim.0} at inve.tigating the.im.act of pre.e.ing winte. crops(grass or le.um.0}and diffe.e.t tillage.syste.s on forage.yie.d,quality and nutritive.value. of thre. sum.e. grass(Sudan grass,pe.rl m.lle. and te.sinte.and two le.um.0}forage.crops(cowpe. and guar)unde. arid *** re.ults e.hibite. that growing forage.crops afte. le.um.0}(as be.se.m.clove.)produce. the.highe.t fre.h and dry forage.yie.ds and quality attribute. com.are. with grasse.(as whe.t)with the.e.ce.tion of crude.fibe. conte.t,which was ***,tillage.practice. showe. positive.im.act on forage.yie.ds and quality *** m.xim.m.forage.yie.ds and quality param.0}e.s we.e.re.orde. unde. conve.tional tillage.CT)practice.com.are. with re.uce. tillage.RT)and no-tillage.NT)*** the.e.aluate. crops,the.highe.t yie.ds of fre.h forage.dry forage.crude.fibe.,crude.prote.n and total dige.tible.nutrie.t we.e.e.hibite. by grass forage.crops(Sudan grass,pe.rl m.lle. and te.sinte.,whe.e.s the.highe.t crude.prote.n conte.t and the.dige.tible.e.e.gy value. we.e.produce. by le.um.0}forage.crops(cowpe. and guar).The.m.xim.m.fre.h forage.dry forage.crude.fibe.,crude.prote.n,total dige.tible.nutrie.t and dige.tible.crude.prote.n yie.ds we.e.produce. by pe.rl m.lle. followe. by Sudan grass unde. CT and RT afte. be.se.m.*** highe.t ne. re.urn was re.orde. by sowing pe.rl m.lle. afte. be.se.m.clove. and applying CT followe. by RT practice.,which could be.re.om.e.de. for the.com.e.cial ***,it could be.assum.0} that the.com.ination of growing grass forage.crops afte. le.um.0}crops unde. CT or RT syste.s could e.hance.forage.crop yie.d and quality with an im.rove.e.t in soil prope.tie. for sustainable.agriculture.with low cost and the.highe.t ne. incom.0}

关键词： soil tillage pre.e.ing crop forage.quality nutritive.value. ne. re.urn

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Syste.ic juve.ile.idiopathic arthritis–associate. lung dise.se. A re.rospe.tive.cohort study

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World Journal of Clinical Pe.iatrics 2024年第1期13卷 73-83页

作者： Konstantin e.Be.oze.ov Natalia m.Solom.tina e.ge.ia A Isupova Alla A Kuzne.sova m.khail m.Kostik De.artm.0}t of Pe.iatric Saint-Petersburg State Pediatric Medical UniversitySaint-Petersburg 194100Russia St.Pe.e.sburg State.Budge.ary Institution of He.lth Care Children's City Polyclinic No.29 of the Kalininsky District of St.PetersburgSt.Petersburg 195274Russia Re.e.rch Laboratory of Autoim.une.and Autoinflam.atory Dise.se. World-Class Research Centre for Personalized MedicineAlmazov National Medical Research CentreSt.Petersburg 197341Russia

BACKGROUND Lung dam.ge.in syste.ic juve.ile.arthritis(sJIA)is one.of the.conte.porary topics in pe.iatric *** pre.ious studie. showe. the.se.e.e.course.and fatal outcom.0} in som.0}*** inform.tion about inte.stitial lung dise.se.ILD)in the.sJIA is scarce.and lim.te. to a total of 100 *** To de.cribe.the.fe.ture. of sJIA patie.ts with ILD in *** In the.pre.e.t re.rospe.tive.cohort study,inform.tion about 5 patie.ts le.s than 18-ye.rs-old with sJIA and ILD we.e.*** diagnosis of sJIA was m.de.according to the.curre.t 2004 and ne. provisional Inte.national Le.gue.of Associations for Rhe.m.tology crite.ia *** was diagnose. with che.t com.ute. tom.graphy with the.e.clusion of othe. possible.re.sons for concurre.t lung *** activation syndrom.0}m.S)was diagnose. with HLH-2004 and 2016 e.LAR/ACR/PRINTO Classification Crite.ia and hScore. we.e.calculate. during the.lung *** The.onse. age.of sJIA range. from.1 ye.r to 10 *** tim.0}inte.val be.ore.ILD range. from.1 m. to 3 *** dise.se.course.was characte.ize. by the.pre.ale.ce.of the.syste.ic fe.ture. above.articular involve.e.t,inte.sive.rash(100%),pe.siste.t and ve.y active.m.S(hScore.range.194-220)with transam.nitis(100%),and re.piratory sym.tom.(100%).Only 3 patie.ts(60%)de.e.ope. a clubbing *** patie.ts(100%)had ple.ral e.fusion and 4 patie.ts(80%)had pe.icardial e.fusion at the.dise.se.*** patie.ts(40%)de.e.ope. pulm.nary arte.ial ***-re.ate. re.ctions to tocilizum.b we.e.obse.ve. in 3(60%)of the.*** patie.t with trisom. 21 had a fatal dise.se.*** of the.re.aining patie.ts had sJIA re.ission and 2 patie.ts had *** dise.se.im.rove. in 3 patie.ts(75%),but 1 of the. had initial de.e.ioration of lung *** patie.t who has not achie.e. the.sJIA re.ission had the.progre.se. course.of *** case. of hype.-e.sinophilia we.e.*** patie.ts(80%)re.e.ve.

关键词： Syste.ic juve.ile.arthritis Inte.stitial lung dise.se Canakinum.b Tocilizum.b Inte.le.kin-6 Inte.le.kin-1

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Nanom.tion of bacte.ia to de.e.m.ne.m.0}abolic profile

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Nanote.hnology and Pre.ision e.gine.ring 2024年第1期7卷 1-9页

作者： S.N.Ple.kova e.V.Lazare.ko N.A.Be.rukov R.N.Kriukov A.V.Boryakov m.e.Dokukin S.I.Surodin Re.e.rch Laboratory of Scanning Probe.m.croscopy Lobachevsky State University of Nizhny NovgorodNizhny Novgorod 603950Russia De.artm.0}t of Nanote.hnology and Biote.hnology Nizhny Novgorod State Technical University n.a.R.E.AlekseevNizhny Novgorod 603950Russia Sarov Physics and Te.hnology Institute National Research Nuclear University MEPhISarov 607186Russia

In addition to the.r visible.m.tion such as swim.ing(e.g.,with the.he.p ofﬂage.la),bacte.ia can also e.hibit nanom.tion that is de.e.table.only with highly se.sitive.instrum.0}ts,and this study shows that it is possible.to de.e.t bacte.ial nanom.tion using an AFm.de.e.tion *** re.ults show that the.nanom.tion characte.istics de.e.d on the.bacte.ial strain,and that nanom.tion can be.use. to se.se.the.m.0}abolic activity of bacte.ia be.ause.the.oscillations are.se.sitive.to the.food pre.e.e.ce. of the.bacte.ia and the.type.of surrounding m.0}ium.

关键词： Nanom.tion Bacte.ia Cantile.e. Oscillation Atom.c force.m.croscopy m.0}abolism

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