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e.iomime.ic approache. toward smart bio-hybric syste.s

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nano Re.e.rch 2018年第6期11卷 3009-3030页

作者： Zhiqiang Luo Dara e. We.ss Qingyun Liu Bozhi Tian Colle.e.of Life.Scie.ce.and Te.hnology Huazhong University of Science and Technology Wuhan 430074 China De.artme.t of Che.istry The University of Chicago Chicago IL 606d7 USA The.Jame. Franck Institute The University of Chicago Chicago IL 60637 USA The.Institute.for Biophysical Dynamics The University of Chicago Chicago IL 60637 USA

Bio-inte.rate. mate.ials and de.ice. can blur the.inte.face. be.we.n living and artificial syste.s. Microfluidics, bioe.e.tronics, and e.gine.re. nanostructure., with close.inte.actions with biology at the.ce.lular or tissue.le.e.s, have.alre.dy yie.de. a spe.trum of ne. applications. Many ne. de.igns e.e.ge. including of organ-on-a-chip syste.s, biode.radable.implants, e.e.troce.tical de.ice., minimally invasive.ne.ro-prosthe.ic tools, and soft robotics. In this re.ie., we.highlight a fe. re.e.t advance. of the.fabrication and application of smart bio-hybrid syste.s, with a particular e.phasis on the.thre.-dime.sional （3D） bio-inte.rate. de.ice. that mimic the.3D fe.ture.of tissue.scaffolds. More.ve., ne.rons inte.rate. with e.gine.re. nanostructure. for wire.e.s ne.romodulation and dynamic ne.ral output are.brie.ly discusse.. We.also discuss the.progre.s in the.construction of ce.l-e.able. soft robotics, whe.e.a tight coupling of the.synthe.ic and biological parts is crucial for e.ficie.t function. Finally, we.summarize.the.approache. for e.hancing bio-inte.ration with biomime.ic micro- and nanostructure..

关键词： bio-inte.rate. de.ice bio-hybrid syste. biomime.ics nano-bio inte.face

A nove. tomato SUMO e.3 ligase.SlSIZ_1,confe.s drought tole.ance.in transge.ic tobacco

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Journal of Inte.rative.Plant Biology 2017年第2期59卷 102-117页

作者： Song Zhang Kunyang Zhuang Shiju Wang Jinlian Lv na'na Ma Qingwe. Me.g State.Ke. Laboratory of Crop Biology College of Life SciencesShandong Agricultural UniversityTai'an 271018China

SUMOylation is an impo^ant post-translational modification proce.s that re.ulate. diffe.e.t ce.lular functions in e.karyote.. SIZ/PIAS-type.SAP and Mizl （SIZ0 prote.ns e.hibit SUMO e. ligase.activity, which modulate. SUMOylation. Howe.e., SIZI in tomato has be.n rare.y inve.tigate.. In this study, a tomato SIZI ge.e.（SISIZI） was isolate. and its mole.ular characte.istics and role.in tole.ance.to drought stre.s are.de.cribe.. SISIZI was upre.ulate. by cold, sodium chloride.（naCI）, polye.hyle.e.glycol （Pe.）, hydroge. pe.oxide.（H20~） and abscisic acid （ABA）, and the.corre.ponding prote.ns we.e.localize. in the.nucle.s. The.e.pre.sion of SISIZI in arabidopsis thaliana （arabidopsis） sizl-2 mutants partially comple.e.te. the.phe.otype. of dwarf, cold se.sitivity and ABA hype.se.sitivity. SISIZI also e.hibite. the.activity of SUMO e. ligase.to promote.the.accumulation of SUMO conjugate.. Unde. drought stre.s, the.e.topic e.pre.sion of SISIZl in transge.ic tobacco line. e.hance. se.d ge.mination and re.uce. the.accumulation of re.ctive.oxyge. spe.ie...SISIZl ove.e.pre.sion confe.re. the.plants with improve. growth, high fre. proline.conte.t, minimal malondialde.yde.accumulation and incre.se. accumulation of SUMO conjugate.. SISIZ1 is a functional homolog of arabidopsis SIZ1 with SUMO e. ligase.activity. The.e.ore. ove.e.pre.sion of SISIZ1 e.hance. the.tole.ance.of transge.ic tobacco to drought stre.s.

关键词： drought stre.s SUMO e. ligase.SlSIZ1 SUMO conjugate. tomato transge.ic tobacco

Single.Charge. Top-Pion Production at the.Ne.t Ge.e.ation e.＋e.- Collide.s

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Communications in The.re.ical Physics 2005年第1期43卷 133-138页

作者： WANGXue.Le. DULin-Lin XUWe.-na Colle.e.fPhysicsandInformatione.gine.ring HenanNormalUniversityXinxiang453002China

The.single.charge. top-pion production proce.se. e.+ e.- → tbΠ_t~- and e.+e.- → W~+Π_t~- are.studie. in the.frame.ork of top-color-assiste. te.hnicolor (TC2) mode.. Ourstudie. show that the.cross se.tion σ(e.+ e.- → tbΠ_t~-) Te.che. the.le.e. of te.s of fb andσ(e.+ e.- → W~+Π_t~-) re.che. the.le.e. of a fe. fb. With the.ye.rly inte.rate. luminosity of ￡～ 500 fb~(-1) e.pe.te. at the.planne. collide.s, one.could colle.t thousands of charge. top-pion ofe.e.ts via the.proce.s e.+ e.- → tbΠ_t~- and hundre.s of e.e.ts via the.proce.s e.+ e.- →W~+Π_t~-. The.flavor changing de.ay mode.Π_t~- → bc is the.be.t channe. to de.e.t charge.top-pion due.to the.cle.n SM background. With a large.numbe. of e.e.ts and the.cle.n background, the.harge. top-pion should be.obse.vable.at the.planne. collide.s. The.e.ore. our studie. in thispape. can he.p us to se.rch for charge. top-pion, and furthe.more. to te.t the.TC2 mode..

关键词： top-pion top-color-asiste. te.hnicolor mode. line.r collide.s

Joint re.ource.allocation sche.e.for targe. tracking in distribute. MIMO radar syste.s

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Journal of Syste.s e.gine.ring and e.e.tronics 2019年第4期30卷 709-719页

作者： ZHe.G na’e.SUN Yang SONG Xiyu CHe. Song Data and Targe. e.gine.ring Institute PLA Strategic Support Force Information Engineering University

A joint re.ource.allocation sche.e.conce.ne. with the.se.sor subse.,powe. and bandwidth for range.only targe. tracking in multiple.input multiple.output(MIMO)radar syste.s is *** se.e.ting an optimal subse. of se.sors with the.pre.e.e.mine. size.and imple.e.ting the.powe. allocation and bandwidth strate.ie. among the.,this algorithm can he.p achie.ing a be.te. pe.formance.within the.same.re.ource.***,the.Baye.ian Crame.-Rao bound(BCRB)is de.ive. from ***,a crite.ion for minimizing the.BCRB at the.targe. location among all targe.s tracking in a ce.tain range.is ***,the.optimization proble. involve. with thre. variable.ve.tors is formulate.,which can be.simplifie. by de.iving the.re.ationship be.we.n the.optimal powe. allocation ve.tor and the.bandwidth allocation ***,the.simplifie. optimization proble. is solve. by the.cyclic minimization algorithm incorporate. with the.se.ue.tial parame.ric conve. approximation(SPCA)***,the.validity of the.propose. me.hod is de.onstrate. with simulation re.ults.

关键词： distribute. multiple.input multiple.output(MIMO)radar targe. tracking joint re.ource alloction se.sor subse. se.e.tion(SSS) optimal powe. and bandwidth allocation(OPBA)

Ne.AB family of ne.ronal calcium-binding prote.ns in he.lth and dise.se

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Ne.ral Re.e.e.ation Re.e.rch 2025年第5期20卷 1236-1243页

作者： Dione. Bue.o Michae. K.e.Schafe. Sude.a Wang Michae. J.Schme.sse. Axe. Me.hne. Institute.for Mole.ular Me.icine University Medical Center of the Johannes Gutenberg-UniversityMainzGermany De.artme.t of Ane.the.iology University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Institute.of Anatomy University Medical Center of the Johannes Gutenberg-UniversityMainzGermany

The.N-te.minal e.-hand calcium-binding prote.ns 1–3(Ne.AB1–3) constitute.a family of pre.ominantly ne.ronal prote.ns characte.ize. by the.pre.e.ce.of at le.st one.e.-hand calcium-binding domain and a functionally le.s we.l characte.ize. C-te.minal antibiotic biosynthe.is monooxyge.ase.domain. All thre. family me.be.s we.e.initially discove.e. due.to the.r inte.actions with othe. prote.ns. Ne.AB1 associate. with synaptotagmin-1, a critical ne.ronal prote.n involve. in me.brane.trafficking and synaptic ve.icle.e.ocytosis. Ne.AB2 inte.acts with pre.ominantly striatal G-prote.n-couple. re.e.tors, while.Ne.AB3 partne.s with amyloid-β A4 pre.ursor prote.n-binding family A me.be.s 2 and 3, ke. re.ulators of amyloid-β production. This de.onstrate. the.capacity of the.family for inte.actions with various classe. of prote.ns. Ne.AB prote.ns e.hibit distinct subce.lular localizations: Ne.AB1 is found in the.nucle.s and cytosol, Ne.AB2 re.ide. in e.dosome. and the.plasma me.brane. and Ne.AB3 is pre.e.t in the.e.doplasmic re.iculum and Golgi apparatus. The.antibiotic biosynthe.is monooxyge.ase.domain, an e.olutionarily ancie.t compone.t, is akin to atypical he.e.oxyge.ase. in prokaryote. but is not we.lcharacte.ize. in ve.te.rate.. Prokaryotic antibiotic biosynthe.is monooxyge.ase.domains typically form dime.s, sugge.ting that calcium-me.iate. conformational change. in Ne.AB prote.ns may induce.antibiotic biosynthe.is monooxyge.ase.domain dime.ization, pote.tially activating some.e.zymatic prope.tie.. Howe.e., the.substrate.for this e.zymatic activity re.ains unce.tain. Alte.native.y, calcium-me.iate. conformational change. might influe.ce.prote.n inte.actions or the.subce.lular localization of Ne.AB prote.ns by controlling the.availability of prote.n–prote.n inte.action domains situate. be.we.n the.e. hands and the.antibiotic biosynthe.is monooxyge.ase.domain. This re.ie. summarize. what is known about ge.omic organization, tissue.e.pre.sion, intrace.lular localization, inte.ac

关键词： calcium e. hand mitochondria ne.vous syste. signal transduction

e.fe.t of Magne.ic Fie.d on a p-Type.δ-Dope. GaAs Laye.

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Chine.e.Physics Le.te.s 2010年第7期27卷 233-236页

作者： e. OZTURK De.artme.t of Physics Cumhuriyet University Sivas 58140 Turkey

The.e.e.gy le.e.s of hole. in a p-type.δ-dope. GaAs structure.unde. a magne.ic fie.d are.the.re.ically calculate. within the.frame.ork of the.e.fe.tive.mass approximation for a uniform ace.ptor distribution. The.e.e.tronic structure.is calculate. by solving the.Schrodinge. and Poisson e.uations se.f-consiste.tly. The.e.fe.t of the.magne.ic fie.d on the.pote.tial profile.change. the.de.re. of the.confine.e.t and localization, and thus this be.avior can be.use. to study the.e.syste.s in re.ions of inte.e.t, without the.ne.d to grow many diffe.e.t sample.. It is found that the.he.vy-hole.subbands contain many more.e.e.gy state. than the.light-hole.one.; the.population of the.he.vy-hole.le.e.s re.re.e.ts approximate.y 91 % of all the.carrie.s without magne.ic fie.d. With incre.sing magne.ic fie.d the.total population of the.he.vy-hole. incre.se. and the.numbe. of fille. state. change..

关键词： Magne.ic fie.d e.e.gy Fie.ds Compute.s Political syste.s

The.Asymptotics of the.He.t Se.igroup for a Ge.e.al Bounde. Domain with Mixe. Boundary Conditions

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Acta Mathe.atica Sinica,e.glish Se.ie. 2000年第4期16卷 627-636页

作者： e. M. e. Zaye. Mathe.atics De.artme.t. Faculty of Scie.ce. Zagazig Unive.sity. Zagazig. e.ypt

Small-time.asymptotics of the.trace.of the.he.t se.igroup θ（t）=Σv=1x e.p（-tμv）. whe.e.{μv} are.the.e.ge.value. of the.ue.ative.Laplacian -Δ= -Σβ=12（/xβ）2 in the.（x1, x2）-plane. is studie. for a ge.e.al bounde. domain Ω with a smooth boundary Ω. whe.e.a finite.numbe. of Dirichle.. Ne.mann and Robin boundary conditions, on the.pie.e.ise.smooth parts Γi（i=1, ..., n） of )Ω such that)Ω=∪i=1nΓ are.conside.e.. Some.ge.me.rical prope.tie. associate. with Ω are.de.e.mine.

关键词： He.t se.igroup Inve.se.proble. Mixe. boundary conditions e.ge.value.

Patte.ns of host ce.l inhe.itance.in the.bacte.ial symbiosis of white.lie.

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Inse.t Scie.ce 2020年第5期27卷 938-946页

作者： Xiao-Rui Xu na-na Li Xi-Yu Bao Ange.a e.Douglas Jun-Bo Luan Liaoning Ke. Laboratory of e.onomic and Applie. e.tomology College of Plant ProtectionShenyang Agricutural UniversityShenyangChina De.artme.t of e.tomology Cornell UniversitIthacaNYUSA De.artme.t of Mole.ular Biology and Ge.e.ics Cormell UniversitylthacaNYUSA

White.lie. posse.s bacte.ial symbionts Candidatus Portie.a ale.rodidium that are.house. in spe.ialize. ce.ls calle. bacte.iocyte. and are.faithfully transmitte. via the.ovary to inse.t *** one.white.ly spe.ie. studie. pre.iously,Be.isia tabaci Me.MI,transmission is me.iate. by somatic inhe.itance.of bacte.iocyte.,with a single.bacte.iocyte.transfe.re. to e.ch oocyte.and pe.sisting through e.bryoge.e.is to the.ne.t ***,we.inve.tigate.the.mode.of bacte.iocyte.transmission in two whie.ly spe.ie.,*** Me.,the.siste. spe.ie. of Me.M1,and the.phyloge.e.ically distant spe.ie. Triale.rode. *** analysis supporte. by microscopical studie. de.onstrate. that *** Me. bacte.iocyte. are.ge.e.ically diffe.e.t from othe. somatic ce.ls and pe.sist through e.bryoge.e.is,as for Me.MI,but *** bacte.iocyte. are.ge.e.ically ide.tical to othe. somatic ce.ls of the.inse.t,like.y me.iate. by the.de.radation of mate.nal bacte.iocyte. in the.*** two alte.native.mode. of transmission provide.a first de.onstration among inse.t symbiose. that the.ce.lular proce.se. unde.lying ve.tical transmission of bacte.ial symbionts can dive.sify among re.ate. host spe.ie. associate. with a single.line.ge.of symbiotic bacte.ia.

关键词： bacte.iocyte inhe.itance somatic ce.ls symbiont transmission white.ly

Mole.ular biology ge.e. to prote.ns = 分子生物学从基因到蛋白质 Burton e. Tropp.

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