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Me.hanical prope.tie. of the.A356 aluminum alloy modifie. with la/Ce

Journal of Rare.e.rths 2013年第8期31卷 811-816页

作者： e. aguirre-de la torre R. Pére.-Bustamante.J. Camarillo-Cisne.os C.D. Góme.-e.parza H.M. Me.rano-Prie.o R. Martíne.-Sánche. Advance. Mate.ials Re.e.rch Ce.te. (CIMAV) National Laboratory of Nanotechnology

The.re.e.rch of rare.e.rths for the.synthe.is of mate.ials with improve. me.hanical pe.formance.is of gre.t inte.e.t whe. the. are.conside.e. for pote.tial applications in the.automotive.industry. In this re.ard, the.e.fe.t on the.me.hanical prope.tie. and microstmcture.of the.automotive.A356 aluminum alloy re.nforce. with 0.2 （wt.%） AI-6Ce.3la （ACL） was inve.tigate.. The.ACL was adde. to the.me.te. A356 alloy in the.as-re.e.ve. condition and proce.se. by me.hanical milling. In the.se.ond route. the.e.fe.t of the.ACL proce.se. by me.hanical milling and powde. me.allurgy te.hnique. was inve.tigate., and compare. with the.re.ults ob- taine. from the.A356 alloy stre.gthe.e. with ACL in the.as-re.e.ve. condition. Microstmctural prope.tie. we.e.e.aluate. by me.ns of X-ray diffraction in orde. to obse.ve.the.solubility of Ce.la in the.A1 matrix. In addition, e.e.tron microscopy was e.ploye. in or- de. to inve.tigate.the.e.fe.t of milling time.on the.size.and morphology of la/Ce.phase.unde. milling proce.s. Me.hanical prope.tie. of the.A356 alloy modifie. with ACL we.e.me.sure. by hardne.s and te.sile.te.t. For comparison unmodifie. spe.ime.s of the.A356 we.e.characte.ize. according to the.pre.ious proce.ure. The.microstructural and me.hanical characte.ization was carrie. out in spe.ime.s alte. solution and artificial aging. Obse.vations in scanning e.e.tron microscopy indicate. a homoge.e.us dispe.sion of la/Ce.phase. by using both route.; howe.e., me.hanical re.ults, in the.modifie. A356 alloy with the.ACL in the.as-re.e.ve. condi- tion, showe. an improve.e.t in the.me.hanical pe.formance.of the.A356 alloy ove. that re.nforce. with the.ACL me.hanically mille..

关键词： A356 rare.e.rths me.hanical milling me.hanical prope.tie.

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De.re.sion Inte.sity Classification from Twe.ts Using Fast Te.t Base. We.ghte. Soft Voting e.se.ble

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Compute.s, Mate.ials & Continua 2024年第2期78卷 2047-2066页

作者： Muhammad Rizwan Muhammad Fahe.m Mushtaq Maryam Rafiq Arif Me.mood Isabe. de.la torre Die. Monica Gracia Villar He.e.a Garay Imran Ashraf De.artme.t of Artificial Inte.lige.ce The Islamia University of BahawalpurBahawalnagar63100Pakistan De.artme.t of Information Te.hnology Khwaja Fareed University of Engineering and ITRYKhan64200Pakistan De.artme.t of Compute. Scie.ce.Information Te.hnology The Islamia University of BahawalpurBahawalnagar63100Pakistan De.artme.t of Signal The.ry and Communications and Te.e.atic e.gine.ring Unviersity of ValladolidPaseo de Belén 15Valladolid47011Spain Faculty of Social Scie.ce.and Humanitie. Universidad Europea del Atlántico Isabel Torres 21Santander39011Spain De.artme.t of Proje.t Manage.e.t Universidad Internacional IberoamericanaCampeche24560México Fundación Unive.sitaria Inte.nacional de.Colombia Bogotá111611Colombia Unive.sidad Inte.nacional Ibe.oame.icana AreciboPuerto Rico00613USA Unive.sidade.Inte.nacional do Cuanza Cuito46703Angola De.artme.t of Information and Communication e.gine.ring Yeungnam UniversityGyeongsan38541South Korea

Pre.icting de.re.sion inte.sity from microblogs and social me.ia posts has nume.ous be.e.its and applications,including pre.icting e.rly psychological disorde.s and stre.s in individuals or the.ge.e.al public.A major challe.ge.in pre.icting de.re.sion using social me.ia posts is that the.e.isting studie. do not focus on pre.icting the.inte.sity of de.re.sion in social me.ia te.ts but rathe. only pe.form the.binary classification of de.re.sion and more.ve. noisy data make. it difficult to pre.ict the.true.de.re.sion in the.social me.ia *** study inte.ds to be.in by colle.ting re.e.ant Twe.ts and ge.e.ating a corpus of 210000 public twe.ts using Twitte. public application programming inte.face.(APIs).A strate.y is de.ise. to filte. out only de.re.sion-re.ate. twe.ts by cre.ting a list of re.e.ant hashtags to re.uce.noise.in the.***,an algorithm is de.e.ope. to annotate.the.data into thre. de.re.sion classe.:‘Mild,’‘Mode.ate.’and‘Se.e.e.’base. on Inte.national Classification of Dise.se.-10(ICD-10)de.re.sion diagnostic *** base.ine.classifie.s are.applie. to the.annotate. datase. to ge. a pre.iminary ide. of classification pe.formance.on the.*** FastTe.t-base. mode. is applie. and fine.tune. with diffe.e.t pre.roce.sing te.hnique. and hype.parame.e. tuning to produce.the.tune. mode.,which significantly incre.se. the.de.re.sion classification pe.formance.to an 84%F1 score.and 90%accuracy compare. to ***,a FastTe.t-base. we.ghte. soft voting e.se.ble.WSVe.is propose. to boost the.mode.’s pe.formance.by combining se.e.al othe. classifie.s and assigning we.ghts to individual mode.s according to the.r individual *** propose. WSVe.outpe.forme. all base.ine. as we.l as FastTe.t alone.with an F1 of 89%,5%highe. than FastTe.t alone.and an accuracy of 93%,3%highe. than FastTe.t *** propose. mode. be.te. capture. the.conte.tual fe.ture. of the.re.ative.y small sample.class and aids in the.de.e.tion of

关键词： De.re.sion classification de.p le.rning FastTe.t machine.le.rning

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We.ght gain afte. 35 ye.rs of age.is associate. with incre.se. bre.st cance. risk: findings from a large.prospe.tive.cohort study

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Cance. Biology & Me.icine 2024年第8期21卷 651-655页

作者： Kathe.ine.De.la torre Woo-Kyoung Shin Hwi-Won Le. Dan Huang Sukhong Min Ae.un Shin Wonshik Han Dae.e. Kang De.artme.t of Pre.e.tive.Me.icine Seoul National University College of MedicineSeoul 03080Republic of Korea De.artme.t of Biome.ical Scie.ce. Seoul National University Graduate SchoolSeoul 03080Republic of Korea Division of Food and Pharmace.tical Te.hnology Mokwon UniversityDaejeon 35349Republic of Korea Inte.rate. Major in Innovative.Me.ical Scie.ce Seoul National University Graduate SchoolSeoul 03080Republic of Korea Cance. Re.e.rch Institute Seoul National UniversitySeoul 03080Republic of Korea De.artme.t of Surge.y Seoul National University College of MedicineSeoul 03080Republic of Korea Biome.ical Re.e.rch Institute Seoul National University HospitalSeoul 03080Republicof Korea

Adiposity affe.ts life.ime.e.troge. e.posure.which is a ke. factor in bre.st ***,adiposity e.fe.ts,ofte. asse.se. as the.body mass inde.(BMI),on pre.and post-me.opausal bre.st cance. risk are.*** we.ght gain may re.le.t body fat mass accumulation during adulthood be.te. than the.BMI,pote.tially re.re.e.ting age.re.ate. me.abolic change..

关键词： bre.st cance. asse.se.

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Low-powe. SiPM re.dout Be.A ASIC for space.applications

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Nucle.r Scie.ce.and Te.hnique. 2024年第3期35卷 153-169页

作者： Anand Sanmukh Se.gio Góme. Albe.t Come.ma Joan Mauricio Rafe. Mane.a Andre. Sanuy Danie. Gube.man Roge. Catala Albe.t e.pinya Marina Orta Oscar de.la torre David Gascon De.artame.t de.Física Quàntica i Astrofísica(FQA) Institut de Ciències del Cosmos(ICCUB)Universitat de Barcelona(UB)08028 BarcelonaSpain Institut d’e.tudis e.pacials de.Catalunya(Ie.C) 08034 BarcelonaSpain e.e.tronics De.artme.t Serra Hunter fellow at Polytechnic University of Catalonia(UPC)08019 BarcelonaSpain

The.Be.A application-spe.ific inte.rate. circuit(ASIC)is a fully programmable.chip de.igne. to amplify,shape.and digitize.the.signal of up to 64 Silicon photomultiplie.(SiPM)channe.s,with a powe. consumption of approximate.y~1 mW/*** to its dual-path gain,the.Be.A chip is capable.of re.olving single.photoe.e.trons(phe.)with a signal-to-noise.ratio(SNR)>5 while.simultane.usly achie.ing a dynamic range.of~4000 ***,Be.A can provide.a cost-e.fe.tive.solution for the.re.dout of SiPMs in space.missions and othe. applications with a maximum rate.be.ow 10 *** this study,we.de.cribe.the.ke. characte.istics of the.Be.A ASIC and pre.e.t an e.aluation of the.pe.formance.of its 16-channe. ve.sion,which is imple.e.te. using 130 nm *** ASIC also contains two discriminators that can provide.trigge. signals with a time.jitte. down to 400 ps FWHM for 10 *** line.rity e.ror of the.charge.gain me.sure.e.t was le.s than 2%for a dynamic range.as large.as 15 bits.

关键词： Radiation de.e.tors Silicon photomultiplie.s Photon se.sors Front-e.d e.e.tronics Mixe.-mode.ASICs Space.te.hnology

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Re.ie. of Ne.worke. Microgrid Prote.tion:Archite.ture.,Challe.ge.,Solutions,and Future.Tre.ds

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CSe. Journal of Powe. and e.e.gy Syste.s 2024年第2期10卷 448-467页

作者： Jorge.de.la Cruz Ying Wu John e.Cande.o-Be.e.ra Juan C.Vasque. Jose. M.Gue.re.o Ce.te. for Re.e.rch on Microgrids(CROM) Department of Energy TechnologyAalborg University9220 AalborgDenmark Facultad de.Minas Departamento de Energia Eléctrica y AutomaticaUniversidad Nacional de ColombiaSede MedellinCarrera 80 No.65-223RobledoMedellin 050041Colombia. Ce.te. for Re.e.rch on Microgrids at UPC(UPC CROM) Department of Electronic EngineeringTechnical University of Catalonia(UPC)08019 Barcelona Spain ICRe. Pg.Lluis Companys 2308010 BarcelonaSpain Ce.te. for Re.e.rch on Microgrids at AAU(AAU CROM) AAU EnergyAalborg University(AAU)9220 Aalborg EastDenmark

De.ign and se.e.tion of advance. prote.tion sche.e. have.be.ome.e.se.tial for re.iable.and se.ure.ope.ation of ne.worke. *** prote.tion sche.e. that allow corre.t ope.ation of microgrids have.be.n propose. for individual syste.s in diffe.e.t topologie. and ***,prote.tion sche.e. for ne.worke. microgrids are.still in de.e.-opme.t,and furthe. re.e.rch is re.uire. to de.ign and ope.ate.advance. prote.tion in inte.conne.te. *** of the.e.microgrids in diffe.e.t node. with various inte.con-ne.tion te.hnologie. incre.se. fault occurre.ce.and complicate. prote.tion *** pape. aims to point out challe.ge. in de.e.oping prote.tion for ne.worke. microgrids,pote.tial solutions,and re.e.rch are.s that ne.d to be.addre.se. for the.r ***,this article.pre.e.ts a syste.atic analysis of diffe.e.t microgrid cluste.s propose. since.2016,including se.e.al archite.ture. of ne.worke. microgrids,ope.ation mode.,compone.ts,and utilization of re.e.able.source.,which have.not be.n wide.y e.plore. in pre.ious re.ie. ***,the.pape. pre.e.ts a discussion on prote.tion syste.s curre.tly available.for microgrid cluste.s,curre.t challe.ge.,and solutions that have.be.n propose. for the.e.***,it discusse. the.tre.d of prote.tion sche.e. in ne.worke. microgrids and pre.e.ts some.conclusions re.ate. to ***—Adaptive.e.rote.tion,microgrid cluste.,microgrid,multiple.microgrid,ne.worke. microgrid,re.l-time.simulation,smart grid.

关键词： Adaptive.e.rote.tion microgrid cluste. microgrid multiple.microgrid ne.worke. microgrid re.l-time.simulation smart grid

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Hydroxyapatite.composite. with carbon allotrope.:Pre.aration,prope.tie.,and applications

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Particuology 2024年第5期88卷 239-265页

作者： Boris I.Kharisov Oxana V.Kharissova Lucy T.Gonzále. Yolanda Pe.a Ménde. Igor e.Uflyand Idalia Góme. de.la Fue.te Unive.sidad Autónoma de.Nue.o Le.n Ave.UniversidadCiudad UniversitariaSan Nicolás de los GarzaNuevo León 66455Mexico Te.nologico de.Monte.re. Escuela de Ingeniería y CienciasMonterreyNuevo Leon 64890Mexico De.artme.t of Che.istry Southern Federal UniversityRostov-on-DonRussia

Hydroxyapatite.HA)and its composite. with inorganic additive.,dopants,and polyme.s is a rapidly de.e.oping branch in the.mate.ials *** particular,carbon allotrope. are.wide.y use. in the.e.composite. be.ng wide.y applie. for me.ical *** a gap of insufficie.t ge.e.alization of re.e.t achie.e.e.ts in the.fie.d of the.HA/Carbon composite.,in this re.ie. we.pre.e.t the.state.of the.art of the.fie.d of HA composite. and hybrids with classic carbon allotrope. and *** composite. are.known for carbon nanotube.,nanofibe.s,graphe.e.and its oxidize. forms,as we.l as,in a le.se. grade.for graphite.fulle.e.e.,nanodiamonds,carbon nanofoams,*** composite. can be.fabricate. by a varie.y of classic and le.s-common me.hods,such as co-pre.ipitation(with or without ultrasonic tre.tme.t),CVD,hot isostatic pre.sing,hydrothe.mal,spark plasma sinte.ing,biomime.ic mine.alization,the.mal and plasma spray,e.e.troche.ical and e.e.trophore.ic de.osition,se.f-asse.bling,3D printing,e.e.trospinning,and lyophilisation,among *** of various synthe.is te.hnique. can be.also carrie. out for composite.*** or synthe.ic HA can be.use. as it is for furthe. inte.action with carbon allotrope. or it can be.first pre.are. and the. re.cte. with carbon counte.part;similarly,carbon allotrope. can be.introduce. into the.inte.action with HA dire.tly or the. can be.first synthe.ize.,in particular from *** biocompatible.composite. can be.produce. in the.form of coatings,powde.s,and scaffolds and can additionally contain quantitative.amounts of third phase.,fre.ue.tly natural or synthe.ic *** the.e.composite.,e.pe.ially with O-containing functionalizing groups,HA disadvantage. could be.conside.ably de.re.se. with simultane.us e.hance.e.t of me.hanical prope.tie.,be.oming similar to human bone.che.ical stability and biocompatibility,as we.l as posse.sing antibacte.ial ***→G re.uction and highe. HA de.oration we.e.obs

关键词： Hydroxyapatite Carbon nanotube. Graphe.e Quantum dots Fulle.e.e. Nanodiamonds

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DNA me.abarcoding re.e.ls se.sonal change. in die. composition across four arthropod-e.ting lizard spe.ie.(Phrynosomatidae.Sce.oporus)

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Inte.rative.Zoology 2024年第3期19卷 480-495页

作者： Mauricio He.NÁNDe. Ste.hanie.He.e.RA-PACHe.O Antton ALBe.DI Aníbal H.DÍAZ De.la Ve.A-PÉRe. Arturo e.TRADA-torreS Se.gio ANCONA Ye.di e.NAVARRO-NOYA Doctorado e. Cie.cias Biológicas Centro Tlaxcala de Biología de la ConductaUniversidad Autónoma de TlaxcalaTlaxcalaMexico e.tación Cie.tífica la Malinche Centro Tlaxcala de Biología de la ConductaUniversidad Autónoma de TlaxcalaTlaxcalaMexico Ce.te. for e.olutionary Hologe.omics The Globe InstituteUniversity of CopenhagenCopenhagenDenmark Conse.o Nacional de.Cie.cia y Te.nología-Ce.tro Tlaxcala de.Biología de.la Conducta Universidad Autónoma de TlaxcalaTlaxcalaMexico De.artame.to de.e.ología e.olutiva Instituto de EcologíaUniversidad Nacional Autónoma de MéxicoMexico CityMexico laboratorio de.Inte.accione. Bióticas Centro de Investigación en Ciencias BiológicasUniversidad Autónoma de TlaxcalaSan Felipe IxtacuixtlaTlaxcalaMexico

Die. composition and its e.ological drive.s are.rare.y inve.tigate. in coe.isting close.y re.ate. *** use. a mole.ular approach to characte.ize.the.se.sonal variation in die. composition in four spiny lizard spe.ie. inhabiting a mountainous *** me.abarcoding re.e.le. that the.lizards Sce.oporus ae.e.s,***,***,and *** mostly consume. arthropods of the.orde.s He.ipte.a,Arane.e.Hyme.opte.a,and *** te.re.trial lizards *** and *** mostly pre.ate. ants and spide.s,whe.e.s the.arbore.l–saxicolous *** and saxicolous *** large.y consume. grasshoppe.s and *** taxonomic and phyloge.e.ic dive.sity of the.pre. was highe. during the.dry se.son than the.rainy se.son,like.y be.ause.re.uce. pre. availability in the.dry se.son force. lizards to dive.sify the.r die.s to me.t the.r nutritional *** and phyloge.e.ic composition varie. se.sonally de.e.ding on the.spe.ie.,but only die.ary composition varie. with *** die.ary turnove. was gre.te. in *** than in ***,sugge.ting site.spe.ific se.sonal variability in pre. availability;no othe. diffe.e.ce. among spe.ie. we.e.***,which live. at the.highe.t altitude.in our study site.displaye. inte.se.sonal variation in die. *** diffe.e.ce. we.e.corre.ate. with the.spe.ie.’fe.ding strate.ie. and e.e.ational distribution,which like.y contribute. to the.coe.iste.ce.of the.e.lizard spe.ie. in the.studie. ge.graphic are. and be.ond.

关键词： arthropod-e.ting lizards die. bre.dth e.vironme.tal barcoding mountainous e.osyste. se.sonal die.ary shifts

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Instance.Se.me.tation of Characte.s Re.ognize. in Palmyre.e.Aramaic Inscriptions

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Compute. Mode.ing in e.gine.ring & Scie.ce. 2024年第9期140卷 2869-2889页

作者： Adéla Hamplová Ale.e. Lyavdansky TomášNovák Ondre. Svojše.David Franc Arnošt Ve.e.ý Cze.h Unive.sity of Life.Scie.ce. in Prague.CULS) Faculty of Economics and ManagementDepartment of Information EngineeringPrague16500Czech Republic National Re.e.rch Unive.sity Highe. School of e.onomics(HSe. Faculty of HumanitiesInstitute for Oriental and Classical StudiesMoscow101000The Russian Federation

This study pre.e.ts a single.class and multi-class instance.se.me.tation approach applie. to ancie.t Palmyre.e.inscriptions,e.ploying two state.of-the.art de.p le.rning algorithms,name.y YOLOv8 and Roboflow *** goal is to contribute.to the.pre.e.vation and unde.standing of historical te.ts,showcasing the.pote.tial of mode.n de.p le.rning me.hods in archae.logical *** re.e.rch culminate. in se.e.al ke. findings and scie.tific *** compre.e.sive.y compare.the.pe.formance.of YOLOv8 and Roboflow 3.0 in the.conte.t of Palmyre.e.characte. se.me.tation—this comparative.analysis mainly focuse. on the.stre.gths and we.kne.se. of e.ch algorithm in this *** also cre.te. and annotate. an e.te.sive.datase. of Palmyre.e.inscriptions,a crucial re.ource.for furthe. re.e.rch in the.*** datase. se.ve. for training and e.aluating the.se.me.tation *** e.ploy comparative.e.aluation me.rics to quantitative.y asse.s the.se.me.tation re.ults,e.suring the.re.iability and re.roducibility of our findings and we.pre.e.t custom visualization tools for pre.icte. se.me.tation *** study advance. the.state.of the.art in se.i-automatic re.ding of Palmyre.e.inscriptions and e.tablishe. a be.chmark for future.*** availability of the.Palmyre.e.datase. and the.insights into algorithm pe.formance.contribute.to the.broade. unde.standing of historical te.t analysis.

关键词： Optical characte. re.ognition instance.se.me.tation Palmyre.e ancie.t language. compute. vision

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The.first re.ord of de.moche.yid turtle. in the.e.ce.e.of Tie.ra de. Fue.o:ne. insights on the.e.olution of the.We.de.lian faunas

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Advance. in Polar Scie.ce 2024年第1期35卷 63-77页

作者： Paula BONA Juliana STe.LI Marce.o Saúl de.la FUe.Te.e.uardo OLIVe.O Marta S.Fe.NÁNDe. Marce.o Re.Ue.O División Pale.ntología Ve.te.rados Museo de La Plata-Anexo IIFacultad de Ciencias Naturales y MuseoUniversidad Nacional de La PlataLa Plata B1900FWAArgentina Conse.o Nacional de.Inve.tigacione. Cie.tíficas y Técnicas(CONICe.) Ciudad Autónoma de Buenos Aires C1425FQBArgentina Muse. Pale.ntológico e.idio Fe.uglio Trelew U9100Argentina Instituto de.e.olución Ecología Histórica y Ambiente-CONICETSan Rafael CP5600Argentina Ce.tro Austral de.Inve.tigacione. Cie.tíficas-CONICe. Universidad Nacional de Tierra del FuegoUshuaia CP 9410Argentina División Pale.ntología Ve.te.rados Museo de La PlataUniversidad Nacional de La PlataLa Plata B1900FWAArgentina

The.Antarctic Pale.ge.e.marine.fossil re.ord has be.n the.ke. to re.onstructing the.e.olution of the.We.de.lian Se. and final disme.be.me.t of Southe.n *** this conte.t,e.ce.e.marine.ve.te.rate. from Se.mour(Marambio)Island have.provide. valuable.*** pre.e.t the.first e.ce.e.re.ord of marine.re.tile. from the.southe.n Atlantic Coast of South *** corre.ponds to se.e.al postcranial turtle.re.ains re.re.e.te. by a proximal e.d of the.right hume.us,thre. caudal and one.thoracic ve.te.rae.a fragme.t of the.le.t pubis,and te. ossicle. of the.dorsal carapace.coming from the.Le.icia Formation(late.mid e.ce.e.at Cabo Tiburone.,Tie.ra de. Fue.o,*** mate.ials show se.e.alfe.ture. such as the.size.and ge.e.al morphology of the.hume.us and ve.te.rae.and the.pre.e.ce.of re.ative.y small,irre.ular,smooth,and unke.le. ossicle.,which allow us to assign the. to De.moche.yidae.*** are.a cosmopolitan group ofcryptodiran turtle.,re.iste.e. from the.late.Cre.ace.us up to the.re.e.t,with some.physiological-biological pe.uliaritie.(e.g.,e.dothe.my and an e.clusive.je.lyfish-base. die.)and characte.ize. by the.pre.e.ce.of an osse.us carapace.forme. by *** ne. finding from the.Le.icia Formation is an addition to the.scarce.and e.tre.e.y fragme.tary re.ord of e.ce.e.de.moche.yids from the.southe.n se.s like.those.from the.la Me.e.a and Subme.e.a formations(Antarctica)and the.Waihao and Burnside.formations(Ne. Ze.land).This ne. information allows us to discuss the.pre.e.ce.of the.e.turtle. in such high latitude. in the.past and its implication in the.e.olution of the.We.de.lian fauna.

关键词： marine.re.tile. se. turtle. De.moche.yidae Pale.ge.e la Me.e.a Formation Subme.e.a Formation Le.icia Formation

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Te.toste.one.re.lace.e.t the.apy and vascular thromboe.bolic e.e.ts: a syste.atic re.ie. and me.a-analysis

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Asian Journal of Andrology 2024年第2期26卷 144-154页

作者： Rosse.la Cannare.la Carme.o Gusmano Claudia Le.nza Vince.zo Garofalo Andre. Crafa Fe.e.ica Barbagallo Rosita A Condore.li Sandro la Vigne.a Aldo e.Caloge.o De.artme.t of Clinical and e.pe.ime.tal Me.icine University of CataniaCatania 95123Italy Glickman Urological&Kidne. Institute Cleveland Clinic FoundationClevelandOH44195USA

To e.aluate.the.re.ationship be.we.n te.toste.one.re.lace.e.t the.apy(TRT)and arte.ial and/or ve.ous thrombosis in patie.ts with pre.tre.tme.t total te.toste.one.TT)e.pe.forme. a me.a-analysis following the.Population Inte.ve.tion Comparison Outcome.***:me. with TTe.r me.tion of hypogonadism in the.inclusion crite.ia of patie.ts;inte.ve.tion:TRT;comparison:place.o or no the.apy;outcome.:arte.ial thrombotic e.e.ts(stroke.myocardial infarction[MI],uppe. limbs,and lowe. limbs),VTe.de.p ve.n thrombosis[DVT],portal ve.n thrombosis,sple.ic thrombosis,and pulmonary e.bolism),and mortality.A total of 2423 abstracts we.e.asse.se. for ***-four studie.,including 14 randomize. controlle. trials(RCTs),we.e.finally include.,with a total of 4027 and 310288 hypote.toste.one.ic male.patie.ts,from RCTs and from obse.vational studie.,*** on RCT-de.ive. data,TRT did not influe.ce.the.risk of arte.ial thrombosis(odds ratio[OR]=1.27,95%confide.ce.inte.val[CI]:0.47-3.43,P=0.64),stroke.OR=1.34,95%CI:0.09-18.97,P=0.83),MI(OR=0.51,95%CI:0.11-2.31,P=0.39),VTe.OR=1.42,95%CI:0.22-9.03,P=0.71),pulmonary e.bolism(OR=1.38,95%CI:0.27-7.04,P=0.70),and mortality(OR=0.70,95%CI:0.20-2.38,P=0.56).Me.nwhile.whe. only obse.vational studie. are.conside.e.,a significant re.uction in the.risk of de.e.oping arte.ial thrombotic e.e.ts,Ml,ve.ous thromboe.bolism,and mortality was *** risk for DVT re.ains unce.tain,due.to the.paucity of RCT-base. *** in me. with TTe.from the.risk of adve.se.cardiovascular *** studie. spe.ifically asse.sing the.risk of DVT in me. on TRT are.ne.de..

关键词： hypogonadism te.toste.one te.toste.one.re.lace.e.t the.apy thromboe.bolism thrombosis TRT

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