检索结果-南通市图书馆

Differential response of injured and healthy retinas to syngeneic and allogeneic transplantation of a clonal cell line of immortalized olfactory ensheathing glia:a double-edged sword

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第8期20卷 2395-2407页

作者： María Norte-Muñoz María Portela-Lomba Paloma Sobrado-Calvo Diana Simón Johnny Di Pierdomenico Alejandro Gallego-Ortega Mar Pérez JoséMCabrera-Maqueda Javier Sierra Manuel vidal-Sanz María Teresa Moreno-Flores Marta Agudo-Barriuso Grupo de Investigación Oftalmología experimental Departamento de OftalmologíaOptometríaOtorrinolaringología y Anatomía PatológicaFacultad de MedicinaUniversidad de MurciaInstituto Murciano de Investigación Biosanitaria(IMIB)Campus de Ciencias de la SaludMurciaSpain experimental Sciences Faculty Universidad Francisco de VitoriaPozuelo de AlarcónMadridSpain Anatomy Histology and Neuroscience DepartmentMedicine FacultyUniversidad Autónoma de MadridMadridSpain Center of Neuroimmunology Service of NeurologyLaboratory of Advanced Imaging in Neuroimmunological DiseasesHospital Clínic of BarcelonaInstitut d’Investigacions Biomèdiques August Pi i Sunyer(IDIBAPS)and Universitat de BarcelonaBarcelonaSpain Medicine Faculty Universidad Francisco de VitoriaPozuelo de AlarcónMadridSpain

Olfactory ensheathing glia promote axonal regeneration in the mammalian central nervous system,including retinal ganglion cell axonal growth through the injured optic ***,it is unknown whether olfactory ensheathing glia also have neuroprotective *** ensheathing glia express brain-derived neurotrophic factor,one of the best neuroprotectants for axotomized retinal ganglion ***,we aimed to investigate the neuroprotective capacity of olfactory ensheating glia after optic nerve *** ensheathing glia cells from an established rat immortalized clonal cell line,TeG3,were intravitreally injected in intact and axotomized retinas in syngeneic and allogeneic mode with or without microglial inhibition or immunosuppressive *** and gene expression analyses were *** bulb-derived primary olfactory ensheathing glia and TeG3 express major histocompatibility complex classⅡ*** and syngenically transplanted TeG3 cells survived in the vitreous for up to 21 days,forming an *** axotomized retinas,only the allogeneic TeG3 transplant rescued retinal ganglion cells at 7 days but not at 21 *** these retinas,microglial anatomical activation was higher than after optic nerve crush *** intact retinas,both transplants activated microglial cells and caused retinal ganglion cell death at 21 days,a loss that was higher after allotransplantation,triggered by pyroptosis and partially rescued by microglial inhibition or ***,neuroprotection of axotomized retinal ganglion cells did not improve with these *** different neuroprotective properties,different toxic effects,and different responses to microglial inhibitory treatments of olfactory ensheathing glia in the retina depending on the type of transplant highlight the importance of thorough preclinical studies to explore these variables.

关键词： cell therapy immune recognition major histocompatibility complex class II(MHCII) neuroprotection olfactory ensheathing glia retinal ganglion cells

editorial review of HPLSe special issue on laboratory astrophysics

在线全文

学校读者我要写书评

暂无评论

High Power Laser Science and engineering 2019年第1期7卷 134-143页

作者： Francisco suzuki-vidal Yutong Li Carolyn Kuranz Colin Danson Blackett Laboratory Imperial College London Institute of Physics Chinese Academy of Sciences Climate and Space Science and engineering University of Michigan AWe plc

In 2018 the journal High Power Laser Science and engineering produced a Special Issue on Laboratory *** scope of the special issue was to span the latest research and reviews on the following topics related to laboratory astrophysics and related *** topics invited for inclusion were:·collisionless shocks;·planetary formation dynamics and planetary interiors;·warm dense matter;·hydrodynamic and magnetohydrodynamic instabilities;·magnetic reconnection;·relativistic plasmas;·magnetic turbulence and magnetic amplification;·nuclear astrophysics;·radiative transfer and radiation hydrodynamics;·target design;·laser-based HeD *** this was not meant as an exhaustive *** is usual with a special issue of this type Guest editors were invited to lead in sourcing articles.

关键词： High Power Laser Science HPLSe laboratory astrophysics

Comparative stability analyses of traditional and selective room-and-pillar mining techniques for sub-horizontal tungsten veins

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2011年第1期18卷 1-8页

作者： vidal Felix Navarro Torres Carlos Dinis da Gama Matilde Costa e Silva Paula Falcao Neves Qiang Xie Mining and Geo-resources engineering Department of IST Technical University of Lisbon 1049-001 Portugal Faculty of Civil engineering Chongqing University Chongqing 400045 China

The stability and productivity concerning a modification on the traditional room and pillar for a new selective technique at the Portuguese Panasqueira Mine have been *** traditional room-and-pillar stoping uses 5.0-m wide rooms with 3.0 m×3.0 m pillars,while the selective room-and-pillar mining technique consists in stoping with rooms of 4.0 m wide and pillars of 4 m×4 m with a subsequent selective cutting of the quartz veins at the mid pillar of approximately 0.5 m high,to obtain a pillar section with an area of 3.0 m×3.0 *** stability and productivity analyses indicate that the selective technique obtains smaller average pillar safety factor,more rock mass displacement,more extraction and selectivity ratios,and ore grade improvement,compared with the traditional *** results show that the selective technique is also more *** proposed selective room-and-pillar mining technique is applicable to any sub-horizontal narrow quartz veins with wolfram,gold,*** as the famous La Rinconada gold mine in the Peruvian Andes.

关键词： mines and mining tungsten deposits productivity stability stoping

Pupil apodization for increasing data storage density

在线全文

学校读者我要写书评

暂无评论

Chinese Optics Letters 2009年第8期7卷 720-723页

作者： vidal F.Canales Pedro J.Valle Jose e.Oti Manuel P.Cagigal Department of Física Aplicada University of CantabriaLos Castros S/NSantander 39005Spain AOTeK S.COOP. Bo San Andrés 19Arrasate-Mondragón 20500Spain

We introduce a technique for increasing density in optical data storage systems. This technique is based on the use of a superresolving filter at the pupil of a confocal readout system. The main characteristic of this confocal readout system is that the light beam traverses twice through the pupil filter. We describe how to analyze the system performance for general filters, but we focus the study on filters with no focus displacement. Although the storage density attainable depends on the filter characteristics, we show that the storage density can be easily duplicated.

关键词： Pupil apodization for increasing data storage density PSF data

Global standard names for the Lowermost Cambrian Series and Stage

在线全文

学校读者我要写书评

暂无评论

episodes 2007年第4期30卷 287-289页

作者： ed Landing Shanchi Peng Loren e. Babcock Gerd Geyer Malgorzata Moczydlowska- vidal New York State Museum Madison Avenue Albany New York 12230 USA. State Key Laboratory of Stratigraphy and Palaeobiology Nanjing Institute of Geology and Palaeontology 39 East Beijing Road Nanjing 210008 China School of earth Sciences The Ohio State University Columbus Ohio 43210 USA Institut für Palaiontologie Bayerische Julius-Maximillians-Universitat Pleicherwall 1 D97070 Würzburg Germany Department of earth Sciences Uppsala University Norbyvaigen 22 Sweden.

The GSSP marking the base of the Cambrian System was ratified by the lUGS in 1992. Ratification of the GSSP point at the base of the Trichophycus pedum Ichnozone in the Fortune Head section, eastern Newfoundland, Canada, automatically defined the conterminant base of the lowermost series and stage of the Cambrian although names for those subdivisions were not proposed at the time of the decision. In 2007, the lUGS ratified the names Terreneuvian Series and Fortunian Stage for these previously unnamed chronostratigraphic subdivisions. The Terreneuvian Series replaces the provisional name ＂Series 1,＂ and the Fortunian Stage replaces the provisional name ＂Stage 1,＂ of the Cambrian System.

关键词：寒武纪全球标准地质学测量方法

Finger pad friction and tactile perception of laser treated,stamped and cold rolled micro-structured stainless steel sheet surfaces

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Friction 2017年第2期5卷 207-218页

作者： S.ZHANG X.ZeNG D.T.A MATTHeWS A.IGARTUA e.RODRIGUeZ-vidal J.CONTReRAS FORTeS e.VAN DeR HeIDe State Key Laboratory of Tribology Tsinghua University Beijing 100084 ChinaLaboratory for Surface Technology and Tribology Faculty of Engineering Technology University of Twente Drienerlolaan 5 Enschede 7522 NB the Netherlands Shanghai Advanced Research Institute Chinese Academy of Sciences China Laboratory for Surface Technology and Tribology Faculty of Engineering Technology University of Twente Drienerlolaan 5 Enschede 7522 NB the NetherlandsTata Steel Research & Development PO Box 10000 IJmuiden 1970CA the Netherlands IK4-Tekniker C/Ignacio Goenaga 5 Eibar 20600 Spain Acerinox europa SAU Los Barrios Spain Laboratory for Surface Technology and Tribology Faculty of Engineering Technology University of Twente Drienerlolaan 5 Enschede 7522 NB the NetherlandsTU Delft Faculty of Civil Engineering and Geosciences Stevinweg 1 Delft 2628 CN the Netherlands

Tactile perception is a complex system,which depends on frictional interactions between skin and *** contact mechanics of tactile friction is governed by many factors such as the state and properties of skin and *** order to discover the connection between perception and tactile friction on textured stainless steel sheets,both perception experiments (subjective) and tactile friction measurements (objective) were performed in this *** perception experiments were carried out by using a panel test method to identify the perceived roughness,perceived stickiness and comfort level from the *** the friction experiments,tactile friction was measured by a multi-axis force/torque transducer in *** perceived stickiness was illustrated as an effective subjective stimulus,which has a negative correlation to the comfort *** significant evidence was revealed to the connection between the perceived roughness and comfort perception,and this relationship may be influenced by the participants' individual experience,gender and moisture level of ***,the kinetic tactile friction was concluded as an objective stimulus to the comfort perception with a negative correlation.

关键词： tactile friction perception pleasant touch biotribology

Low-Cost Tiled Display System Architecture with Dynamic Web-Based Management

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China Communications 2022年第10期19卷 143-168页

作者： Daniel Marfil Fernando Boronat F.Javier Pastor Anna vidal Communications Department Gandia CampusUniversitat Politecnica de ValenciaCalle Paraninfo146730Grao de GandiaValencia(Spain) Drawing Department Gandia CampusUniversitat Politecnica de ValenciaCalle Paraninfo146730Grao de GandiaValencia(Spain) Applied Mathematics Department Gandia CampusUniversitat Politecnica de ValenciaCalle Paraninfo146730Grao de GandiaValencia(Spain)

In this paper, a scalable hardware and software architecture for tiled display systems (a.k.a. videowalls), which can be implemented by using low-cost devices, together with a dynamic web-based management and configuration service are proposed. It has been designed to support both stored and live broadcast/broadband content, in mosaic or warp distributions. The displays and devices can be dynamically configured via web in different ways: the displays can create a single display of a larger size;or they can be configured in a customized way in order to playout different media contents in different display combinations. As display renderers, low-cost devices are proposed as the main hardware element to obtain affordable videowall systems. As a proof of concept, two prototypes have been implemented, including an accurate synchronization mechanism based on a Master/Slave control scheme and aggressive and smooth playout adjustment techniques. To evidence the good performance of the prototypes and configuration service, both objective and subjective evaluations have been conducted regarding synchronization accuracy and usability. On the one hand, the mean values of the asynchronies between the video playout processes in each display are kept below 25ms (i.e., frame accuracy). On the other hand, the obtained usability score in the System Usability Scale (SUS) test has been 88.65, which is considered as excellent.

关键词： AMP media synchronization multi-screen playout adjustment tiled displays videowall

A slow-growth high-mortality meta-analysis for insects： A comment on Chen and Chen

在线全文

学校读者我要写书评

暂无评论

Insect Science 2018年第2期25卷 352-354页

作者： Shannon M. Murphy Mayra C. vidal Claudia J. Hallagan elizabeth e. Barnes e. Dale Broder Department of Biological Sciences University of Denver Denver CO US

Dear editor, Insect Science recently published a meta-analysis that tried to test support for the slow-growth high-mortality （hereafter SG-HM） hypothesis （Chen＆ Chen, 2018）. Meta-analysis is a powerful statistical tool used to quantitatively compare and summarize multiple studies （Arnqvist ＆ Wooster, 1995）. However, results from a meta-analysis must be carefully interpreted when only limited sample sizes are available. Many conclusions made by Chen and Chen （2018） are based on low sam- rile sizes and/or have small fail-safe numbers,

关键词：

Therapeutic potential of insulin-like growth factor 2 in Huntington's disease: controlling proteostasis to alleviate the load of misfolded protein

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2021年第8期16卷 1564-1565页

作者： Paulina Troncoso-escudero Claudio Hetz Rene L.vidal Biomedical Neuroscience Institute Faculty of MedicineUniversity of ChileSantiagoChile Center for Geroscience Brain Health and MetabolismSantiagoChile Program of Cellular and Molecular Biology Institute of Biomedical SciencesUniversity of ChileSantiagoChile Center for Integrative Biology Faculty of SciencesUniversity MayorChile Buck Institute for Research on Aging NovatoCAUSA

Huntington's disease(HD) is an inherited autosomal dominant neurodegenerative disorder characterized by the development of adult-onset motor dysfunction,psychiatric disturbances and intellectual *** is associated with an expansion of CAG repeat sequence in the huntingtin gene(Htt).exon 1 of Htt normally contains between 6 to 35 CAG repeats,whereas in patients affected with HD it contains more than 40 trinucleotides.

关键词： Huntington Therapeutic stasis