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非开放磁体导航MRI引导下52例肝活检经验

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国际医学放射学杂志 2016年第5期 589-590页

作者： M.Moche S.Heinig N.Garnov J.Fuchs t-O.petersen D.Seider 陈军 Department of Diagnostic and Interventional Radiology Leipzig University Hospital

摘要目的评价非开放磁体导航MRI引导下的肝局灶性病变活检的临床与诊断效率。材料与方法 52例病人行55次活检。采用光学设备示踪的MRI导航系统用于图像引导和磁体外活检针置入。快速对照成像实时观察穿刺针的实际位置。记录活检流程与... 详细信息

摘要目的评价非开放磁体导航MRI引导下的肝局灶性病变活检的临床与诊断效率。材料与方法 52例病人行55次活检。采用光学设备示踪的MRI导航系统用于图像引导和磁体外活检针置入。快速对照成像实时观察穿刺针的实际位置。记录活检流程与持续时间,根据组织学检查及临床过

关键词： MRI 磁体机械元件诊断准确度

(η^(5)-C_(5)H_(5))_(2)Nb[CH_(2)Si(CH_(3))_(3)]_(2)的晶体结构和EPR研究

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高等学校化学学报 1985年第2期6卷 103-108页

作者：刘举正 petersen,J.L. 吉林大学理论化学研究所美国West Virginia大学化学系

合成了(η^(5)-C_(5)H_(5))_(2)Nb[CH_(2)Si(CH_(3))_(3)]_(2)化合物,并测定了它的晶体结构及溶液和玻璃态固体的EPR;通过计算机模拟玻璃态固体EPR得到了g和t的分量;测得最高占据分子轨道的a^(2)/b^(2)=10.3。

关键词：晶体结构分子轨道计算机模拟玻璃态 EPR

白介素-33至白介素-13信号级联调节小鼠胃组织上皮化生

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英国医学杂志中文版 2018年第7期21卷 418-418页

作者： Christine P petersen Anne R Meyer Carlo De Salvo Eunyoung Choi Cameron Schlegel Alec petersen Amy C Engevik Nripesh Prasad Shawn E Levy R Stokes Peebles theresa t Pizarro James R Goldenring 李佳宁(译) 吴东(校) 不详北京协和医院消化科

目的选择性活化巨噬细胞（Alternativelyactivated macrophages, M2）与胃部解痉多肽表达性化生（spasmolytic polypeptide-expressingmetaplasia, SPEM）过程相关。然而，诱导SPEM的确切机制及关键介质尚不明确。研究设计为确定这一... 详细信息

目的选择性活化巨噬细胞（Alternativelyactivated macrophages, M2）与胃部解痉多肽表达性化生（spasmolytic polypeptide-expressingmetaplasia, SPEM）过程相关。然而，诱导SPEM的确切机制及关键介质尚不明确。研究设计为确定这一过程中的关键基因，分离胃部SPEM小鼠（DMP-777处理）及高级胃部SPEM小鼠（L635处理）胃体的巨噬细胞进行RNA测序。评估白介素．33、白介素-33受体（St2）及白介素-13基因敲除小鼠，经L635处理急性壁细胞缺失后对上皮细胞化生过程的影响。结果胃部上皮化生相关性巨噬细胞中可鉴定出M2极化亚群。高级胃部SPEM小鼠巨噬细胞中自介素-33的表达显著上调。L635可在野生型小鼠胃组织中诱导上皮化生，但在白介素-33及白介素．33受体敲除鼠中未观察到这一现象。尽管在诱导上皮化生过程中不需白介素．5及白介素-9，白介素-13基因敲除小鼠无法在L635诱导下发生上皮化生。对白介素-33受体基因敲除小鼠应用白介素-13，可重新诱导急性壁细胞缺失后的上皮化生。结论壁细胞缺失后上皮化生及巨噬细胞极化过程通过白介素．33及白介素-13的细胞信号网络协调进行，将损伤应答过程中固有黏膜机制及M2浸润联系起来。

关键词： IL-13 组织变形调整老鼠串联信号胃

经导管动脉内植入新型股动脉闭合器后对MR增强血管成像的影响

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国际医学放射学杂志 2010年第4期 400-401页

作者： O.K.Mohrs S.E.petersen B.Nowak H.U.Kauczor t.Voigtlaender 郭丽君 Department of Cardiovascular Imaging at Alice-Hospital Darmstadt RadiologyDieburger Strasse 29-3164287 DarmstadtGermany

目的评价病人经导管动脉内植入新型股动脉闭合器后,行MR成像的安全性及MR增强血管成像的伪影。方法10例病人行冠状动脉造影并植入股动脉闭合器后24h内,依次行MR成

关键词：闭合器伪影 MR 血管成像股动脉经导管动脉内

冠状动脉搭桥术并非痴呆或阿尔茨海默病的危险因素

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世界核心医学期刊文摘(神经病学分册) 2006年第2期 41-42页

作者： Knopman D.S. petersen R.C. 赵天智 Department of Neurology Mayo Clinic 200 First Street SW Rochester MN 55905 United States.Dr

Objective: to study coronary artery bypass grafting (CABG) as a risk factor for dementia and Alzheimer disease (AD) using a case-control design. Methods: the authors used the records-linkage system of the Rochester Epidemiology Project to ascertain incident cases of dementia in Rochester, MN, for the 5-year period 1990 to 1994. the authors defined dementia and AD using the criteria of the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV). Each case was individually matched by age (±1 year) and sex to a person drawn randomly from the same population, and free of dementia in the index year (year of onset of dementia in the matched case). Results: Among 557 dementia cases, 24 (4.3%) had undergone a CABG prior to the onset of dementia with a median lag time of 5.5 years (range = 0.1 to 15.9). Among 557 controls, 28 subjects (5.0%) had undergone a CABG prior to the index year with a median lag time 3.9 years (rang e = 0.1 to 12.3); OR = 0.85 (95%CI = 0.49 to 1.49; p = 0.57) for dementia and O R = 0.78 (95%CI = 0.39 to 1.56; p = 0.48) for AD. the findings did not change a fter adjustment for education. the perioperative courses of cases and controls w ere comparable. Analyses including only the 481 cases of dementia with presumed neurodegenerative or cerebrovascular etiology were also negative. Conclusions: t his population-based case-control study suggests that coronary artery bypass g rafting is not a major risk factor for dementia overall, or for Alzheimer diseas e.

关键词：搭桥术危险因素危险隐患阿尔茨海默病冠状动脉

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应用概率地震危险计算期望损失

世界地震译丛 2000年第5期31卷 40-49页

作者：曹天青 M.D.petersen C.H.Cramer t.R.toppozada M.S.Reichle J.F.Davis 曹学锋孙振凯不详中国地震局地球物理研究所

在期望值计算的基础上,应用全部损失在承保人与受保人之间分配的概念,系统地给出通过概率地震危险计算期望损失的公式。计算中用到了从加速度到烈度到损失因子(破坏值与财产值的比率)的转换关系.地震危险值取自加利福尼亚4个地区,分别... 详细信息

在期望值计算的基础上,应用全部损失在承保人与受保人之间分配的概念,系统地给出通过概率地震危险计算期望损失的公式。计算中用到了从加速度到烈度到损失因子(破坏值与财产值的比率)的转换关系.地震危险值取自加利福尼亚4个地区,分别是加利福尼亚典型的高、低地震危险区以及北部和南部各一个人口最稠密地区。计算结果表明,期望损失受危险性和土质条件影响很大。分别对应于烈度、加速度和损失因子的部分损失值显示,与低危险区相比,高危险区的总损失更多地来自于高烈度和加速度。对应于损失因子的部分损失表明,即便是在高危险区,大部分损失仍来自低于15％～20％的损失因子。这个结果在总损失额大于免赔额时有重要影响。承保人的损失计算表明,仅仅5％的免赔额就使承保人在高危险区减少了40％～50％的损失,在低危险区则减少更多。不足额保险和通货膨胀的影响增加了承保人的损失,但小于免赔额在减少损失方面的影响。计算表明,关键在于调整地面运动与损失因子的转换关系。另外,土质条件校正需要用更多的近期强地面运动和地震破坏数据进行校准。

关键词：承保人免赔额损失计算期不足额保险通货膨胀产值烈度地震土质条件

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维生素E和多奈哌齐治疗轻度认知功能障碍

世界核心医学期刊文摘（神经病学分册） 2005年第10期1卷 5-6页

作者： petersen R.C. thomas R.G. Grundman M. 郭俊 Alzheimer’ s Disease Research Center Mayo Clinic College of Medicine 200 First St. SW R ochester MN 55905 United States Dr.

BACKGROUND: Mild cognitive impairment is a transitional state between the cog nitive changes of normal aging and early Alzheimer’ s disease. MEtHODS: In a do uble- blind study, we evaluated subjects with the amnestic subtype of mild cogn itive impairment. Subjects were randomly assigned to receive 2000 IU of vitamin E daily, 10 mg of donepezil daily, or placebo for three years. the primary outco me was clinically possible or probable Alzheimer’ s disease; secondary outcomes were cognition and function. RESULtS: A total of 769 subjects were enrolled, an d possible or probable Alzheimer’ s disease developed in 212. the overall rate of progression from mild cognitive impairment to Alzheimer’ s disease was 16 pe rcent per year. As compared with the placebo group, there were no significant di fferences in the probability of progression to Alzheimer’ s disease in the vita min E group (hazard ratio, 1.02; 95 percent confidence interval, 0.74 to 1.41; P =0.91) or the donepezil group (hazard ratio, 0.80; 95 percent confidence interva l, 0.57 to 1.13; P=0.42) during the three years of treatment. Prespecified analy ses of the treatment effects at 6- month intervals showed that as compared with the placebo group, the donepezil group had a reduced likelihood of progression to Alzheimer’ s disease during the first 12 months of the study (P=0.04), a fin ding supported by the secondary outcome measures. Among carriers of one or more apolipoprotein E e 4 alleles, the benefit of donepezil was evident throughout th e three- year follow- up. there were no significant differences in the rate of progression to Alzheimer’ s disease between the vitamin E and placebo groups a t any point, either among all patients or among apolipoprotein E e 4 carriers. C ONCLUSIONS: Vitamin E had no benefit in patients with mild cognitive impairment. Although donepezil therapy was associated with a lower rate of progression to A lzheimer’ s disease during the first 12 months of treatment, the rate of progr

关键词：多奈哌齐阿尔茨海默病认知功能进展率安慰剂载脂蛋白双盲研究携带者老化性随机分配

Performance and calibration of quark/gluon-jet taggers using 140 fb^(-1) of pp collisions at √s=13 teV with the AtLAS detector

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Chinese Physics C 2024年第2期48卷 1-25页

作者： G. Aad B. Abbott K. Abeling N.J. Abicht S.H. Abidi A. Aboulhorma H. Abramowicz H. Abreu Y. Abulaiti B.S. Acharya C. Adam Bourdarios L. Adamczyk S.V. Addepalli M.J. Addison J. Adelman A. Adiguzel t. Adye A.A. Affolder Y. Afik M.N. Agaras J. Agarwala A. Aggarwal C. Agheorghiesei A. Ahmad F. Ahmadov W.S. Ahmed S. Ahuja X. Ai G. Aielli A. Aikot M. Ait tamlihat B. Aitbenchikh I. Aizenberg M. Akbiyik t.P.A. Åkesson A.V. Akimov D. Akiyama N.N. Akolkar K. Al Khoury G.L. Alberghi J. Albert P. Albicocco G.L. Albouy S. Alderweireldt M. Aleksa I.N. Aleksandrov C. Alexa t. Alexopoulos F. Alfonsi M. Algren M. Alhroob B. Ali H.M.J. Ali S. Ali S.W. Alibocus M. Aliev G. Alimonti W. Alkakhi C. Allaire B.M.M. Allbrooke J.F. Allen C.A. Allendes Flores P.P. Allport A. Aloisio F. Alonso C. Alpigiani M. Alvarez Estevez A. Alvarez Fernandez M. Alves Cardoso M.G. Alviggi M. Aly Y. Amaral Coutinho A. Ambler C. Amelung M. Amerl C.G. Ames D. Amidei S.P. Amor Dos Santos K.R. Amos V. Ananiev C. Anastopoulos t. Andeen J.K. Anders S.Y. Andrean A. Andreazza S. Angelidakis A. Angerami A.V. Anisenkov A. Annovi C. Antel M.t. Anthony E. Antipov M. Antonelli F. Anulli M. Aoki t. Aoki J.A. Aparisi Pozo M.A. Aparo L. Aperio Bella C. Appelt A. Apyan N. Aranzabal S.J. Arbiol Val C. Arcangeletti A.t.H. Arce E. Arena J-F. Arguin S. Argyropoulos J.-H. Arling O. Arnaez H. Arnold G. Artoni H. Asada K. Asai S. Asai N.A. Asbah J. Assahsah K. Assamagan R. Astalos S. Atashi R.J. Atkin M. Atkinson H. Atmani P.A. Atmasiddha K. Augsten S. Auricchio A.D. Auriol V.A. Austrup G. Avolio K. Axiotis G. Azuelos D. Babal H. Bachacou K. Bachas A. Bachiu F. Backman A. Badea P. Bagnaia M. Bahmani A.J. Bailey V.R. Bailey J.t. Baines L. Baines O.K. Baker E. Bakos D. Bakshi Gupta V. Balakrishnan R. Balasubramanian E.M. Baldin P. Balek E. Ballabene F. Balli L.M. Baltes W.K. Balunas J. Balz E. Banas M. Bandieramonte A. Bandyopadhyay S. Bansal L. Barak M. Barakat E.L. Barberio D. Barberis M. Barbero M.Z. Barel K.N. Barends t. Barillari M-S. Barisits t. Barklow P. Baron D.A. Baron Mo the AtLAS Collaboration

the identification of jets originating from quarks and gluons,often referred to as quark/gluon tagging,plays an important role in various analyses performed at the Large Hadron Collider,as Standard Model measurements and searches for new particles decaying to quarks often rely on suppressing a large gluon-induced *** paper describes the measurement of the efficiencies of quark/gluon taggers developed within the AtLAS Collaboration,using √s=13 teV proton–proton collision data with an integrated luminosity of 140 fb^(-1) collected by the AtLAS *** taggers with high performances in rejecting jets from gluon over jets from quarks are studied:one tagger is based on requirements on the number of inner-detector tracks associated with the jet,and the other combines several jet substructure observables using a boosted decision tree.A method is established to determine the quark/gluon fraction in data,by using quark/gluon-enriched subsamples defined by the jet *** in tagging efficiency between data and simulation are provided for jets with transverse momentum between 500 GeV and 2 teV and for multiple tagger working points.

关键词： AtLAS JEt QUARK GLUON tAGGING

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长距离输气管线用X120级钢管的研究

焊管 2006年第3期29卷 27-32页

作者： D.P.Fairchild W.J.Sisak C.W.petersen S.D.Papka M.L.Macia K.t.Corbett R.J.t.Appleby J.Y.Koo N.V.Bangaru M.S.Weir 张帆美国埃克森-美孚石油公司中国石油天然气管道工程有限公司河北廊坊065000

X120级高强度管线钢的发展为天然气生产商提供了将长距离输气管线总造价降低5%～15%的机会,进而可降低向市场输送天然气的价格.成本降低来源于多个方面,包括材料、施工、（气体）压缩以及与综合设计方案结合所带来的节约.介绍了X120钢... 详细信息

X120级高强度管线钢的发展为天然气生产商提供了将长距离输气管线总造价降低5%～15%的机会,进而可降低向市场输送天然气的价格.成本降低来源于多个方面,包括材料、施工、（气体）压缩以及与综合设计方案结合所带来的节约.介绍了X120钢级发展方案的概况,包括大规模的试验和环缝焊接,同时讨论了X120级管线钢实际应用的方案,在这些方案中管道承压较高,管径较小,最终工程总造价可节约5%～15%.

关键词：输气管道 X120钢级性能研究应用方案